The natural anti-tumor compound Celastrol targets a Myb-C/EBPβ-p300 transcriptional module implicated in myeloid gene expression
出版年份 2018 全文链接
标题
The natural anti-tumor compound Celastrol targets a Myb-C/EBPβ-p300 transcriptional module implicated in myeloid gene expression
作者
关键词
Cysteine, Acute myeloid leukemia, Fibroblasts, Reporter genes, Transcription factors, Chickens, Gene expression, Transfection
出版物
PLoS One
Volume 13, Issue 2, Pages e0190934
出版商
Public Library of Science (PLoS)
发表日期
2018-02-03
DOI
10.1371/journal.pone.0190934
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Helenalin Acetate, a Natural Sesquiterpene Lactone with Anti-inflammatory and Anti-cancer Activity, Disrupts the Cooperation of CCAAT Box/Enhancer-binding Protein β (C/EBPβ) and Co-activator p300
- (2016) Anke Jakobs et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- C/EBPβ regulates homeostatic and oncogenic gastric cell proliferation
- (2016) Goncalo Regalo et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Small-Molecule Disruption of the Myb/p300 Cooperation Targets Acute Myeloid Leukemia Cells
- (2016) Sagar Uttarkar et al. MOLECULAR CANCER THERAPEUTICS
- Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction
- (2015) Sagar Uttarkar et al. BLOOD
- Naphthol AS-E Phosphate Inhibits the Activity of the Transcription Factor Myb by Blocking the Interaction with the KIX Domain of the Coactivator p300
- (2015) S. Uttarkar et al. MOLECULAR CANCER THERAPEUTICS
- BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia
- (2015) Jae-Seok Roe et al. MOLECULAR CELL
- CCAAT/enhancer binding protein β induces motility and invasion of glioblastoma cells through transcriptional regulation of the calcium binding protein S100A4
- (2015) Diana Aguilar-Morante et al. Oncotarget
- An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element
- (2014) M. R. Mansour et al. SCIENCE
- Structural insights into interactions of C/EBP transcriptional activators with the Taz2 domain of p300
- (2014) Prasenjit Bhaumik et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
- (2013) Jakob Lovén et al. CELL
- Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
- (2013) Warren A. Whyte et al. CELL
- Super-Enhancers in the Control of Cell Identity and Disease
- (2013) Denes Hnisz et al. CELL
- Interaction and Cooperation of the CCAAT-box Enhancer-binding Protein β (C/EBPβ) with the Homeodomain-interacting Protein Kinase 2 (Hipk2)
- (2013) Simone Steinmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas
- (2013) NATURE GENETICS
- An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance
- (2011) J. Zuber et al. GENES & DEVELOPMENT
- Inhibition of Myb-dependent gene expression by the sesquiterpene lactone mexicanin-I
- (2011) T Bujnicki et al. LEUKEMIA
- Celastrol: Molecular targets of Thunder God Vine
- (2010) Antero Salminen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Crosstalk between C/EBPβ phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code
- (2010) Elisabeth Kowenz-Leutz et al. EMBO JOURNAL
- C/EBP regulates transcription factors critical for proliferation and survival of multiple myeloma cells
- (2009) R. Pal et al. BLOOD
- Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a Transcriptional Program Shared with Embryonic Rather Than Adult Stem Cells
- (2009) Tim C.P. Somervaille et al. Cell Stem Cell
- The transcriptional network for mesenchymal transformation of brain tumours
- (2009) Maria Stella Carro et al. NATURE
- v-Myc inhibits C/EBPβ activity by preventing C/EBPβ-induced phosphorylation of the co-activator p300
- (2009) S Steinmann et al. ONCOGENE
- Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck
- (2009) M. Persson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- C/EBPβ regulates metastatic gene expression and confers TNF-α resistance to prostate cancer cells
- (2009) Myoung H. Kim et al. PROSTATE
- G9a-mediated Lysine Methylation Alters the Function of CCAAT/Enhancer-binding Protein-β
- (2008) Ole Pless et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- C/EBP Induces Chromatin Opening at a Cell-Type-Specific Enhancer
- (2008) A. Plachetka et al. MOLECULAR AND CELLULAR BIOLOGY
- Acetylation and deacetylation regulate CCAAT/enhancer binding protein β at K39 in mediating gene transcription
- (2008) Teresa I. Ceseña et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started