Article
Nutrition & Dietetics
Sigrun Henjum, Synne Groufh-Jacobsen, Allen Lindsay, Ellen Raael, Anna Maria Israelsson, Setareh Shahab-Ferdows, Daniela Hampel
Summary: Plant-based diets may lead to vitamin B12 deficiency, but folate intake is increased. A study on Norwegian vegans and vegetarians found that their B12 status was adequate, while folate levels were higher in vegetarians.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Medicine, General & Internal
Maximilian Andreas Storz, Alexander Mueller, Lisa Niederreiter, Amy M. Zimmermann-Klemd, Martin Suarez-Alvarez, Stefanie Kowarschik, Monique Strittmatter, Evelyn Schlachter, Cristian Pasluosta, Roman Huber, Luciana Hannibal
Summary: The study found that even among homogeneously healthy individuals, different diets led to measurable differences in dietary intake and health biomarkers. Plant-based diets, especially the vegan diet, showed the most favorable patterns of lipid metabolism and glycemic control, but had the lowest food intake of vitamin B12.
ANNALS OF MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Sigrun Henjum, Synne Groufh-Jacobsen, Tonje Holte Stea, Live Edvardsen Tonheim, Kari Almendingen
Summary: Although the majority of participants had sufficient iron status despite consuming a plant-based diet, female vegans and vegetarians of reproductive age are at risk of low iron status and should have their iron status monitored regularly.
Article
Medical Laboratory Technology
Anders Abildgaard, Cindy Soendersoe Knudsen, Carsten Schriver Hoejskov, Eva Greibe, Tina Parkner
Summary: This study aimed to establish age-adjusted reference intervals for plasma B12 and serum/plasma MMA in the Danish population. The results showed that the concentrations of B12 and MMA are closely related to age and vary among different age groups. Therefore, it is suggested to use age-dependent cut-off values for screening B12 deficiency.
CLINICA CHIMICA ACTA
(2022)
Review
Food Science & Technology
Katie E. Lane, Megan Wilson, Teuta G. Hellon, Ian G. Davies
Summary: Emerging research examines the effects of plant-based omega-3 on vegetarians and vegans, finding that microalgal oil supplements can increase O3I levels, while high-dose flaxseed or echium seed oil supplements may not. Further studies are needed to establish optimal EPA and DHA ratios and dosages for vegetarian and vegan populations.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Nutrition & Dietetics
Patricia Lipari Pinto, Cristina Florindo, Patricia Janeiro, Rita Loureiro Santos, Sandra Mexia, Hugo Rocha, Isabel Tavares de Almeida, Laura Vilarinho, Ana Gaspar
Summary: Early diagnosis and intervention in vitamin B12 deficiency in exclusively breastfed infants by mothers with low vitamin B12 are crucial in preventing irreversible neurologic damage, megaloblastic anemia, and failure to thrive. Monitoring serum vitamin B12 levels during pregnancy is important. Acquired B12 deficiency should be ruled out before proceeding in a differential diagnosis of cobalamin metabolism deficits, methylmalonic acidemia, and homocystinuria.
Article
Agriculture, Multidisciplinary
Mengle Wang, Stefan Asam, Jianqi Chen, Michael Rychlik
Summary: The study developed a method for the simultaneous determination of four cobalamins, demonstrating excellent sensitivity, recovery, accuracy, and reproducibility.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Review
Agriculture, Dairy & Animal Science
Gerardo Siani, Beatrice Mercaldo, Maria Chiara Alterisio, Antonio Di Loria
Summary: Cobalamin plays a crucial role in cellular metabolism, particularly in processes such as DNA synthesis and mitochondrial metabolism. In cats, Cobalamin is bound by intrinsic factor and absorbed in the ileal tract. Diagnostic biomarkers for B12 status in cats include decreased levels of circulating total cobalamin and increased levels of methylmalonic acid. Therapy for hypocobalaminemia depends on the underlying disease, and oral cobalamin supplementation has been shown to be successful in dogs and cats.
Article
Multidisciplinary Sciences
Markus Muessig, Tamara M. Pfeiler, Boris Egloff
Summary: Research found that there are some differences in the Big Five personality traits between vegetarians and vegans. Based on two studies, it was found that vegetarians score slightly higher in Neuroticism, while vegans score slightly higher in Openness. However, there are no differences in Conscientiousness, Extraversion, or Agreeableness.
Article
Nutrition & Dietetics
Li Li, Qi Huang, Linjian Yang, Rui Zhang, Leili Gao, Xueyao Han, Linong Ji, Xiantong Zou
Summary: There is an association between non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) with levels of vitamin B12 and associated metabolites, while MMA and HCY may be associated with an increased risk for advanced fibrosis.
Article
Nutrition & Dietetics
Samuel Berkins, Helgi Birgir Schioth, Gull Rukh
Summary: The study found no significant association between vitamin B6, B12, and folate intakes and both global and subcortical brain volumes among participants with depression. However, vitamin B12 intake was positively associated with right pallidum among non-depressed participants, and a significant interaction between vitamin B12 intake and depression status on the right pallidum was observed. Additionally, a significant interaction between folate intake and depression status on grey matter volume and left thalamus was observed.
Article
Biochemical Research Methods
Arjen M. Punt, Kim C. M. van der Elst, Alwin D. R. Huitema, Eef G. W. M. Lentjes
Summary: Protein precipitation solvent trichloroacetic acid (TCA), combined with stable isotope labeled internal standard, is widely used in the analysis of compounds in serum and plasma with LC-MS/MS. However, long-term use of TCA was found to have negative effects on assay performance, affecting the source of the MS. To mitigate these effects, it is recommended to use a low sample injection volume and/or shift the mobile phase to waste during TCA elution in LC-MS/MS analysis.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2023)
Review
Food Science & Technology
Linnea Barebring, Christel Lamberg-Allardt, Birna Thorisdottir, Alfons Ramel, Fredrik Soderlund, Erik Kristoffer Arnesen, Bright I. Nwaru, Jutta Dierkes, Agneta Akesson
Summary: This systematic review aimed to assess the evidence for whether habitual or different levels of experimental intake of vitamin B12 from diet and supplements is sufficient to ensure adequate B12 status in groups most susceptible to vitamin B12 deficiency. The search yielded 18 included studies, and the conclusion was that the evidence is currently insufficient to determine if or which level of B12 intake is sufficient to maintain adequate status for all included populations.
FOOD & NUTRITION RESEARCH
(2023)
Review
Medical Laboratory Technology
Agata Sobczynska-Malefora, Edgard Delvin, Andrew McCaddon, Kourosh R. Ahmadi, Dominic J. Harrington
Summary: Vitamin B-12 is an essential cofactor in two metabolic pathways and is primarily obtained from animal-based foods. Deficiency in B-12 can mimic various illnesses and requires attention from different medical specialists for accurate diagnosis and treatment. Current tests and treatment options for B-12 deficiency have limitations that need to be addressed for better assessment and management.
CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES
(2021)
Article
Endocrinology & Metabolism
Carl Jenkinson, Reena Desai, Malcolm D. McLeod, Jonathan Wolf Mueller, Martin Hewison, David J. Handelsman
Summary: This study analyzed the contribution of sulfate and glucuronide vitamin D metabolites relative to unconjugated levels in human serum. The results showed that sulfate conjugates formed a higher proportion of circulating vitamin D metabolites compared to glucuronide conjugates. The findings suggest that a combination of both conjugated and unconjugated measurements may provide a more accurate assessment of vitamin D status.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Nutrition & Dietetics
Pilar De Miguel-Etayo, Luis A. Moreno, Javier Santabarbara, Miguel Martin-Matillas, Maria Cristina Azcona-San Julian, Amelia Marti del Moral, Cristina Campoy, Ascension Marcos, Jesus Ma Garagorri
CLINICAL NUTRITION
(2019)
Article
Nutrition & Dietetics
Angelica Gallego-Narbon, Belen Zapatera, M. Pilar Vaquero
Article
Nutrition & Dietetics
Ana M. Salvador, Elena Garcia-Maldonado, Angelica Gallego-Narbon, Belen Zapatera, M. Pilar Vaquero
Article
Nutrition & Dietetics
Kevin D. Cashman, Mairead E. Kiely, Rikke Andersen, Ida M. Gronborg, Katja H. Madsen, Janna Nissen, Inge Tetens, Laura Tripkovic, Susan A. Lanham-New, Laura Toxqui, M. Pilar Vaquero, Ulrike Trautvetter, Gerhard Jahreis, Vikram V. Mistry, Bonny L. Specker, Juergen Hower, Anette Knoll, Dennis Wagner, Reinhold Vieth, Inger Ohlund, Pia Karlsland Akeson, Neil R. Brett, Hope A. Weiler, Christian Ritz
Summary: IPD analysis shows that the vitamin D intake needed to maintain certain serum levels is higher than previously estimated through standard meta-regression analysis using aggregate data. The study provides further evidence that a food-based approach with a daily intake of 12 μg of vitamin D can prevent deficiency in the general population.
EUROPEAN JOURNAL OF NUTRITION
(2021)
Article
Multidisciplinary Sciences
M. Pilar Vaquero, Daniel Martinez-Maqueda, Angelica Gallego-Narbon, Belen Zapatera, Jara Perez-Jimenez
Article
Nutrition & Dietetics
Esther Garcia-Diez, Marta Cuesta-Hervas, Ana M. Veses-Alcobendas, Oscar Alonso-Gordo, Elena Garcia-Maldonado, Miriam Martinez-Suarez, Beatriz Herranz, M. Pilar Vaquero, Maria Dolores alvarez, Jara Perez-Jimenez
Summary: The study found that single grape powder supplementation did not significantly modify postprandial responses in obese subjects, likely due to insufficient polyphenol dosage. Further research is needed to explore the effects of a combination of grape with other polyphenol-rich products or chronic supplementation with grape powder on postprandial responses.
EUROPEAN JOURNAL OF NUTRITION
(2021)
Article
Endocrinology & Metabolism
M. Pilar Vaquero, Miriam Martinez-Suarez, Angel Garcia-Quismondo, Francisco J. del Canizo, Francisco J. Sanchez-Muniz
Summary: There is a lack of research on the relationship between iron status, obesity, and type 2 diabetes mellitus (T2DM). This study found that patients with obesity and T2DM may have altered iron metabolism. Women had lower iron markers but higher transferrin markers than men. The diabesity group showed the highest markers of inflammation and insulin resistance, with the lowest iron saturation.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Review
Food Science & Technology
Alexandra Alcorta, Adria Porta, Amparo Tarrega, Maria Dolores Alvarez, M. Pilar Vaquero
Summary: Plant-based diets have gained popularity in reducing environmental impact, improving health, and animal welfare. While the numbers of vegetarians and vegans have increased significantly in recent years, concerns remain regarding the sustainability, safety, and labeling of animal food substitutes.
Article
Plant Sciences
Angelica Gallego-Narbon, Jun Wen, Jing Liu, Virginia Valcarcel
Summary: The advances in sequencing techniques and analytical development have provided an opportunity to study the evolutionary history of lineages under complex patterns of evolution. This study used Hyb-Seq to analyze the phylogeny of the Asian Palmate group (AsPG) in the ginseng family (Araliaceae). The results suggested early radiation and hybridization events in the early evolution of the group. The findings support the hypothesis of radiation and identify extensive signals of hybridization and incomplete lineage sorting.
JOURNAL OF SYSTEMATICS AND EVOLUTION
(2022)
Article
Plant Sciences
Alejandro Alonso, Angelica Gallego-Narbon, Marina Coca-de-la-Iglesia, David Monjas, Nagore G. Medina, Mario Fernandez-Mazuecos, Virginia Valcarcel
Summary: The study aimed to evaluate the role of geographical and ecological forces in the origin and evolution of Madeiran ivy. The results showed that climatic differences played a major role in differentiating Madeiran ivy from other ivy species, and that the successful colonization of Madeira was mainly due to its adaptation to the Macaronesian climate.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Nutrition & Dietetics
Elena Garcia-Maldonado, Alexandra Alcorta, Belen Zapatera, M. Pilar Vaquero
Summary: This study investigated the serum fatty acid profile of lacto-ovo vegetarian, vegan, and omnivorous adults, and analyzed the effects of consuming a vegetable origin DHA supplement on the fatty acid profile. The results showed that the supplement effectively increased serum DHA levels and improved the n-6/n-3 ratio.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Elena Garcia-Maldonado, Belen Zapatera, Alexandra Alcorta, M. Pilar Vaquero
Summary: In this study, 207 Spanish adults were surveyed for their diet, physical characteristics, body composition, hematological and metabolic markers. The findings suggest that consuming a plant-based diet, combined with moderate to high physical activity, provides similar protection against cardiometabolic diseases compared to omnivorous diets.
Review
Nutrition & Dietetics
Elena Garcia-Maldonado, Angelica Gallego-Narbon, Ma Pilar Vaquero
NUTRICION HOSPITALARIA
(2019)
Article
Nutrition & Dietetics
Angelica Gallego-Narbon, Belen Zapatera, Laura Barrios, M. Pilar Vaquero
JOURNAL OF NUTRITIONAL SCIENCE
(2019)