标题
(Re)generating Human Beta Cells: Status, Pitfalls, and Perspectives
作者
关键词
-
出版物
PHYSIOLOGICAL REVIEWS
Volume 98, Issue 3, Pages 1143-1167
出版商
American Physiological Society
发表日期
2018-05-02
DOI
10.1152/physrev.00034.2016
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Artemether Does Not Turn α Cells into β Cells
- (2018) Talitha van der Meulen et al. Cell Metabolism
- Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2
- (2017) Nuria Cerdá-Esteban et al. Nature Communications
- Activation of the Wnt/β-catenin pathway in pancreatic beta cells during the compensatory islet hyperplasia in prediabetic mice
- (2016) D.A. Maschio et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- SerpinB1 Promotes Pancreatic β Cell Proliferation
- (2016) Abdelfattah El Ouaamari et al. Cell Metabolism
- PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2
- (2016) Jayalakshmi Lakshmipathi et al. DIABETES
- Inhibition of DYRK1A Stimulates Human β-Cell Proliferation
- (2016) Ercument Dirice et al. DIABETES
- Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor
- (2016) Rachel E. Stamateris et al. DIABETES
- Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia
- (2016) Bernhard J. Hering et al. DIABETES CARE
- Novel factors modulating human β-cell proliferation
- (2016) J. Shirakawa et al. DIABETES OBESITY & METABOLISM
- Extreme obesity induces massive beta cell expansion in mice through self-renewal and does not alter the beta cell lineage
- (2016) Aaron R. Cox et al. DIABETOLOGIA
- FoxO1 Plays an Important Role in Regulating β-Cell Compensation for Insulin Resistance in Male Mice
- (2016) Ting Zhang et al. ENDOCRINOLOGY
- Effects of Obesity and Diabetes on α- and β-Cell Mass in Surgically Resected Human Pancreas
- (2016) Jun Inaishi et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Sfrp5mediates glucose-induced proliferation in rat pancreatic β-cells
- (2016) Binbin Guan et al. JOURNAL OF ENDOCRINOLOGY
- Generation of Functional Beta-Like Cells from Human Exocrine Pancreas
- (2016) Maria J. Lima et al. PLoS One
- Human pancreatic beta-like cells converted from fibroblasts
- (2016) Saiyong Zhu et al. Nature Communications
- Generation of stem cell-derived β-cells from patients with type 1 diabetes
- (2016) Jeffrey R. Millman et al. Nature Communications
- Adipose- and muscle-derived Wnts trigger pancreatic β-cell adaptation to systemic insulin resistance
- (2016) Kamil Kozinski et al. Scientific Reports
- Resolving Discrepant Findings on ANGPTL8 in β-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy
- (2016) Aaron R. Cox et al. PLoS One
- Pregnancy Hyperglycemia in Prolactin Receptor Mutant, but Not Prolactin Mutant, Mice and Feeding-Responsive Regulation of Placental Lactogen Genes Implies Placental Control of Maternal Glucose Homeostasis1
- (2015) Saara M. Rawn et al. BIOLOGY OF REPRODUCTION
- Osteoprotegerin and Denosumab Stimulate Human Beta Cell Proliferation through Inhibition of the Receptor Activator of NF-κB Ligand Pathway
- (2015) Nagesha Guthalu Kondegowda et al. Cell Metabolism
- Human pancreas development
- (2015) R. E. Jennings et al. DEVELOPMENT
- Augmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human β-Cells
- (2015) Hainan Chen et al. DIABETES
- Induction of the ChREBPβ Isoform Is Essential for Glucose-Stimulated β-Cell Proliferation
- (2015) Pili Zhang et al. DIABETES
- New insights into the architecture of the islet of Langerhans: a focused cross-species assessment
- (2015) Rafael Arrojo e Drigo et al. DIABETOLOGIA
- Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro
- (2015) H. A. Russ et al. EMBO JOURNAL
- Insulin demand regulates β cell number via the unfolded protein response
- (2015) Rohit B. Sharma et al. JOURNAL OF CLINICAL INVESTIGATION
- TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors
- (2015) Inês Cebola et al. NATURE CELL BIOLOGY
- A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication
- (2015) Peng Wang et al. NATURE MEDICINE
- Diabetes mellitus—advances and challenges in human β-cell proliferation
- (2015) Peng Wang et al. Nature Reviews Endocrinology
- Ex Vivo Expansion and Differentiation of Human and Mouse Fetal Pancreatic Progenitors Are Modulated by Epidermal Growth Factor
- (2015) Paola Bonfanti et al. STEM CELLS AND DEVELOPMENT
- Inhibition of DYRK1A and GSK3B induces human β-cell proliferation
- (2015) Weijun Shen et al. Nature Communications
- A human beta cell line with drug inducible excision of immortalizing transgenes
- (2015) Marion Benazra et al. Molecular Metabolism
- Prolactin Receptors and Placental Lactogen Drive Male Mouse Pancreatic Islets to Pregnancy-Related mRNA Changes
- (2015) Lotte Goyvaerts et al. PLoS One
- Novel GATA6 Mutations in Patients with Pancreatic Agenesis and Congenital Heart Malformations
- (2015) Christina S. Chao et al. PLoS One
- Generation of Functional Human Pancreatic β Cells In Vitro
- (2014) Felicia W. Pagliuca et al. CELL
- Perspectives on the Activities of ANGPTL8/Betatrophin
- (2014) Peng Yi et al. CELL
- ANGPTL8/Betatrophin Does Not Control Pancreatic Beta Cell Expansion
- (2014) Viktoria Gusarova et al. CELL
- Reprogramming of human pancreatic exocrine cells to β-like cells
- (2014) M Lemper et al. CELL DEATH AND DIFFERENTIATION
- Analysis of Transcription Factors Key for Mouse Pancreatic Development Establishes NKX2-2 and MNX1 Mutations as Causes of Neonatal Diabetes in Man
- (2014) Sarah E. Flanagan et al. Cell Metabolism
- Reduced Ki67 Staining in the Postmortem State Calls Into Question Past Conclusions About the Lack of Turnover of Adult Human β-Cells
- (2014) Brooke A. Sullivan et al. DIABETES
- Betatrophin Versus Bitter-Trophin and the Elephant in the Room: Time for a New Normal in -Cell Regeneration Research
- (2014) A. F. Stewart DIABETES
- Human -Cell Proliferation and Intracellular Signaling Part 2: Still Driving in the Dark Without a Road Map
- (2014) E. Bernal-Mizrachi et al. DIABETES
- GATA4 Mutations Are a Cause of Neonatal and Childhood-Onset Diabetes
- (2014) C. Shaw-Smith et al. DIABETES
- Menin determines K-RAS proliferative outputs in endocrine cells
- (2014) Chester E. Chamberlain et al. JOURNAL OF CLINICAL INVESTIGATION
- Development of a conditionally immortalized human pancreatic β cell line
- (2014) Raphaël Scharfmann et al. JOURNAL OF CLINICAL INVESTIGATION
- Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers
- (2014) Simona Chera et al. NATURE
- Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells
- (2014) Alireza Rezania et al. NATURE BIOTECHNOLOGY
- Role of Endogenous GLP-1 and GIP in Beta Cell Compensatory Responses to Insulin Resistance and Cellular Stress
- (2014) Srividya Vasu et al. PLoS One
- Contribution of a Non-β-Cell Source to β-Cell Mass during Pregnancy
- (2014) Chiara Toselli et al. PLoS One
- Redifferentiation of Adult Human β Cells Expanded In Vitro by Inhibition of the WNT Pathway
- (2014) Ayelet Lenz et al. PLoS One
- Differentiated human stem cells resemble fetal, not adult, β cells
- (2014) Sinisa Hrvatin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell therapy for type 1 diabetes
- (2014) K. R. Muir et al. QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
- Revealing transcription factors during human pancreatic β cell development
- (2014) Elizabeth Conrad et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Pancreas development in humans
- (2014) Fong Cheng Pan et al. Current Opinion in Endocrinology Diabetes and Obesity
- Increased Circulating Betatrophin Concentrations in Patients with Type 2 Diabetes
- (2014) Daniel Espes et al. International Journal of Endocrinology
- The window period of NEUROGENIN3 during human gestation
- (2014) Rachel J Salisbury et al. Islets
- Islet β cell mass in diabetes and how it relates to function, birth, and death
- (2013) Gordon C. Weir et al. Annals of the New York Academy of Sciences
- RETRACTED: Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation
- (2013) Peng Yi et al. CELL
- Epigenomic Analysis of Multilineage Differentiation of Human Embryonic Stem Cells
- (2013) Wei Xie et al. CELL
- Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell
- (2013) Sudhir G. Tattikota et al. Cell Metabolism
- Toward the Development of a Global Induced Pluripotent Stem Cell Library
- (2013) Marc Turner et al. Cell Stem Cell
- Adult Duct-Lining Cells Can Reprogram into β-like Cells Able to Counter Repeated Cycles of Toxin-Induced Diabetes
- (2013) Keith Al-Hasani et al. DEVELOPMENTAL CELL
- Suppression of Epithelial-to-Mesenchymal Transitioning Enhances Ex Vivo Reprogramming of Human Exocrine Pancreatic Tissue Toward Functional Insulin-Producing β-Like Cells
- (2013) Maria João Lima et al. DIABETES
- Elevated Mouse Hepatic Betatrophin Expression Does Not Increase Human -Cell Replication in the Transplant Setting
- (2013) Y. Jiao et al. DIABETES
- Hepatocyte Growth Factor/c-Met Signaling Is Required for -Cell Regeneration
- (2013) J. C. Alvarez-Perez et al. DIABETES
- Conversion of Mature Human -Cells Into Glucagon-Producing -Cells
- (2013) H. S. Spijker et al. DIABETES
- Development of the Human Pancreas From Foregut to Endocrine Commitment
- (2013) R. E. Jennings et al. DIABETES
- Transcription factor gene MNX1 is a novel cause of permanent neonatal diabetes in a consanguineous family
- (2013) A. Bonnefond et al. DIABETES & METABOLISM
- BiallelicPDX1(insulin promoter factor 1) mutations causing neonatal diabetes without exocrine pancreatic insufficiency
- (2013) E. De Franco et al. DIABETIC MEDICINE
- Increased circulating levels of betatrophin in individuals with long-standing type 1 diabetes
- (2013) Daniel Espes et al. DIABETOLOGIA
- Downregulation of Sfrp5 promotes beta cell proliferation during obesity in the rat
- (2013) Sandra A. Rebuffat et al. DIABETOLOGIA
- Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes
- (2013) Valeria Nesca et al. DIABETOLOGIA
- Anonymous sources: where do adult β cells come from?
- (2013) Michael S. German JOURNAL OF CLINICAL INVESTIGATION
- No evidence for β cell neogenesis in murine adult pancreas
- (2013) Xiangwei Xiao et al. JOURNAL OF CLINICAL INVESTIGATION
- Epigenomic plasticity enables human pancreatic α to β cell reprogramming
- (2013) Nuria C. Bramswig et al. JOURNAL OF CLINICAL INVESTIGATION
- Small-Molecule Inducer of β Cell Proliferation Identified by High-Throughput Screening
- (2013) Weijun Shen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Nutrient Sensing, Metabolism, and Cell Growth Control
- (2013) Hai-Xin Yuan et al. MOLECULAR CELL
- Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice
- (2013) Luc Baeyens et al. NATURE BIOTECHNOLOGY
- Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis
- (2013) Michael N Weedon et al. NATURE GENETICS
- Mechanisms of Diabetic Complications
- (2013) Josephine M. Forbes et al. PHYSIOLOGICAL REVIEWS
- Serotonin regulates glucose-stimulated insulin secretion from pancreatic cells during pregnancy
- (2013) M. Ohara-Imaizumi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization of polyhormonal insulin-producing cells derived in vitro from human embryonic stem cells
- (2013) Jennifer E. Bruin et al. Stem Cell Research
- Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo
- (2013) Alireza Rezania et al. STEM CELLS
- The Inactivation of Arx in Pancreatic α-Cells Triggers Their Neogenesis and Conversion into Functional β-Like Cells
- (2013) Monica Courtney et al. PLoS Genetics
- Potent Induction Immunotherapy Promotes Long-Term Insulin Independence After Islet Transplantation in Type 1 Diabetes
- (2012) M. D. Bellin et al. AMERICAN JOURNAL OF TRANSPLANTATION
- In vitro Generation of Functional Insulin-producing Cells from Lipoaspirated Human Adipose Tissue-derived Stem Cells
- (2012) Mohamad Lizan Mohamad Buang et al. ARCHIVES OF MEDICAL RESEARCH
- Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure
- (2012) Chutima Talchai et al. CELL
- Differentiation of Human Adipose Tissue-Derived Stem Cells into Aggregates of Insulin-Producing Cells through the Overexpression of Pancreatic and Duodenal Homeobox Gene-1
- (2012) Jiyeon Lee et al. CELL TRANSPLANTATION
- ChREBP Mediates Glucose-Stimulated Pancreatic -Cell Proliferation
- (2012) M. R. Metukuri et al. DIABETES
- Maturation of Human Embryonic Stem Cell-Derived Pancreatic Progenitors Into Functional Islets Capable of Treating Pre-existing Diabetes in Mice
- (2012) A. Rezania et al. DIABETES
- -Cell Mass and Turnover in Humans: Effects of obesity and aging
- (2012) Y. Saisho et al. DIABETES CARE
- Hepatocyte Growth Factor Plays a Key Role in Insulin Resistance-Associated Compensatory Mechanisms
- (2012) Tiago G. Araújo et al. ENDOCRINOLOGY
- Redifferentiation of Expanded Human Pancreatic β-Cell-derived Cells by Inhibition of the NOTCH Pathway
- (2012) Yael Bar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Formation of a Human β-Cell Population within Pancreatic Islets Is Set Early in Life
- (2012) Brigid E. Gregg et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity
- (2012) Cécile Jacovetti et al. JOURNAL OF CLINICAL INVESTIGATION
- GW8510 Increases Insulin Expression in Pancreatic Alpha Cells through Activation of p53 Transcriptional Activity
- (2012) Dina Fomina-Yadlin et al. PLoS One
- Crosstalk between the developing pancreas and its blood vessels: An evolving dialog
- (2012) Alethia Villasenor et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines
- (2011) Christoph Bock et al. CELL
- Control of Pancreatic β Cell Regeneration by Glucose Metabolism
- (2011) Shay Porat et al. Cell Metabolism
- The Adult Mouse and Human Pancreas Contain Rare Multipotent Stem Cells that Express Insulin
- (2011) Simon R. Smukler et al. Cell Stem Cell
- Combination Therapy with a Dipeptidyl Peptidase-4 Inhibitor and a Proton Pump Inhibitor Induces β-Cell Neogenesis from Adult Human Pancreatic Duct Cells Implanted in Immunodeficient Mice
- (2011) Wilma L. Suarez-Pinzon et al. CELL TRANSPLANTATION
- Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas
- (2011) J. L. Kopp et al. DEVELOPMENT
- Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas
- (2011) D. Kopinke et al. DEVELOPMENT
- Pancreas organogenesis: From bud to plexus to gland
- (2011) Fong Cheng Pan et al. DEVELOPMENTAL DYNAMICS
- Specific Glucose-Induced Control of Insulin Receptor Substrate-2 Expression Is Mediated via Ca 2+ -Dependent Calcineurin/NFAT Signaling in Primary Pancreatic Islet β-Cells
- (2011) Damien Demozay et al. DIABETES
- Autologous Umbilical Cord Blood Transfusion in Young Children With Type 1 Diabetes Fails to Preserve C-Peptide
- (2011) M. J. Haller et al. DIABETES CARE
- Longevity of human islet α- and β-cells
- (2011) M. Cnop et al. DIABETES OBESITY & METABOLISM
- The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells
- (2011) C. L. Basford et al. DIABETOLOGIA
- Immunohistochemical characterisation of cells co-producing insulin and glucagon in the developing human pancreas
- (2011) M. J. Riedel et al. DIABETOLOGIA
- miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors
- (2011) Tal Melkman-Zehavi et al. EMBO JOURNAL
- Loss of Foxd3 Results in Decreased β-Cell Proliferation and Glucose Intolerance During Pregnancy
- (2011) Jennifer L. Plank et al. ENDOCRINOLOGY
- Participation of Akt, Menin, and p21 in Pregnancy-Induced β-Cell Proliferation
- (2011) Elizabeth Hughes et al. ENDOCRINOLOGY
- Guards and Culprits in the Endoplasmic Reticulum: Glucolipotoxicity andβ-Cell Failure in Type II Diabetes
- (2011) Udayakumar Karunakaran et al. Experimental Diabetes Research
- A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion
- (2011) Philippe Ravassard et al. JOURNAL OF CLINICAL INVESTIGATION
- Type 2 diabetes across generations: from pathophysiology to prevention and management
- (2011) Christopher J Nolan et al. LANCET
- GATA6 haploinsufficiency causes pancreatic agenesis in humans
- (2011) Hana Lango Allen et al. NATURE GENETICS
- Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration
- (2011) Chris Jopling et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Islet-Like Cell Aggregates Generated from Human Adipose Tissue Derived Stem Cells Ameliorate Experimental Diabetes in Mice
- (2011) Vikash Chandra et al. PLoS One
- Insulin-Producing Cells Generated from Dedifferentiated Human Pancreatic Beta Cells Expanded In Vitro
- (2011) Holger A. Russ et al. PLoS One
- Ectopic PDX-1 Expression Directly Reprograms Human Keratinocytes along Pancreatic Insulin-Producing Cells Fate
- (2011) Michal Mauda-Havakuk et al. PLoS One
- Kinetics and genomic profiling of adult human and mouse β-cell maturation
- (2011) Marta Szabat et al. Islets
- Non-β-cell progenitors of β-cells in pregnant mice
- (2011) Sylvie Abouna et al. Organogenesis
- Developmental Stages in Human Embryos: Revised and New Measurements
- (2010) Ronan O’Rahilly et al. CELLS TISSUES ORGANS
- Human bone marrow-derived mesenchymal cells differentiate and mature into endocrine pancreatic lineage in vivo
- (2010) Smruti M. Phadnis et al. CYTOTHERAPY
- Glucose and aging control the quiescence period that follows pancreatic beta cell replication
- (2010) S. J. Salpeter et al. DEVELOPMENT
- Disruption of Hepatocyte Growth Factor/c-Met Signaling Enhances Pancreatic -Cell Death and Accelerates the Onset of Diabetes
- (2010) J. Mellado-Gil et al. DIABETES
- -Cell Replication Is Increased in Donor Organs From Young Patients After Prolonged Life Support
- (2010) P. I. Veld et al. DIABETES
- Homozygous Mutations in NEUROD1 Are Responsible for a Novel Syndrome of Permanent Neonatal Diabetes and Neurological Abnormalities
- (2010) O. Rubio-Cabezas et al. DIABETES
- -Cell Growth and Regeneration: Replication Is Only Part of the Story
- (2010) S. Bonner-Weir et al. DIABETES
- Regeneration of insulin production by autologous bone marrow blood autotransplantation in patients with type 1 diabetes
- (2010) E. Esmatjes et al. DIABETOLOGIA
- Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD–severe combined immunodeficiency (SCID) mice
- (2010) H. E. Levitt et al. DIABETOLOGIA
- Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy
- (2010) A. Schraenen et al. DIABETOLOGIA
- Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy
- (2010) A. E. Butler et al. DIABETOLOGIA
- β-Cell Mass Dynamics and Islet Cell Plasticity in Human Type 2 Diabetes
- (2010) Stephen C. Hanley et al. ENDOCRINOLOGY
- Novel GLIS3 mutations demonstrate an extended multisystem phenotype
- (2010) P Dimitri et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Significant Human β-Cell Turnover Is Limited to the First Three Decades of Life as Determined byin VivoThymidine Analog Incorporation and Radiocarbon Dating
- (2010) S. Perl et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Regulation of pancreatic islet gene expression in mouse islets by pregnancy
- (2010) B T Layden et al. JOURNAL OF ENDOCRINOLOGY
- Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss
- (2010) Fabrizio Thorel et al. NATURE
- Rfx6 directs islet formation and insulin production in mice and humans
- (2010) Stuart B. Smith et al. NATURE
- Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine
- (2010) Kenichiro Furuyama et al. NATURE GENETICS
- Serotonin regulates pancreatic beta cell mass during pregnancy
- (2010) Hail Kim et al. NATURE MEDICINE
- Large Islets, Beta-Cell Proliferation, and a Glucokinase Mutation
- (2010) Sameer Kassem et al. NEW ENGLAND JOURNAL OF MEDICINE
- Adipose Tissue Derived Stem Cells for Regeneration and Differentiation into Insulin-Producing Cells
- (2010) Song Cheol Kim et al. Current Stem Cell Research & Therapy
- The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells
- (2009) Patrick Collombat et al. CELL
- Pancreatic Exocrine Duct Cells Give Rise to Insulin-Producing β Cells during Embryogenesis but Not after Birth
- (2009) Myriam Solar et al. DEVELOPMENTAL CELL
- Gestational Diabetes Mellitus Resulting From Impaired -Cell Compensation in the Absence of FoxM1, a Novel Downstream Effector of Placental Lactogen
- (2009) H. Zhang et al. DIABETES
- The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation
- (2009) M. Cnop et al. DIABETOLOGIA
- β-cell development and turnover during prenatal life in humans
- (2009) Juris J Meier et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- C-Peptide Levels and Insulin Independence Following Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus
- (2009) Carlos E. B. Couri JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Transdifferentiation of human adipose tissue-derived stromal cells into insulin-producing clusters
- (2009) Hanayuki Okura et al. JOURNAL OF ARTIFICIAL ORGANS
- Exendin-4 Promotes Liver Cell Proliferation and Enhances thePDX-1-induced Liver to Pancreas Transdifferentiation Process
- (2009) Vered Aviv et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Endocrine Cell Clustering During Human Pancreas Development
- (2009) Jongmin Jeon et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis
- (2009) Leanne Bellamy et al. LANCET
- Glucose Effects on Beta-Cell Growth and Survival Require Activation of Insulin Receptors and Insulin Receptor Substrate 2
- (2009) A. Assmann et al. MOLECULAR AND CELLULAR BIOLOGY
- The Transcriptional Response of the Islet to Pregnancy in Mice
- (2009) Sebastian Rieck et al. MOLECULAR ENDOCRINOLOGY
- Generation of pluripotent stem cells from patients with type 1 diabetes
- (2009) R. Maehr et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- miR-375 maintains normal pancreatic - and -cell mass
- (2009) M. N. Poy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expansion of β-cell mass in response to pregnancy
- (2009) Sebastian Rieck et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Combination Therapy with Glucagon-Like Peptide-1 and Gastrin Induces β-Cell Neogenesis from Pancreatic Duct Cells in Human Islets Transplanted in Immunodeficient Diabetic Mice
- (2008) Wilma L. Suarez-Pinzon et al. CELL TRANSPLANTATION
- Biphasic Ngn3 expression in the developing pancreas
- (2008) Alethia Villasenor et al. DEVELOPMENTAL DYNAMICS
- Transcriptional dynamics of endodermal organ formation
- (2008) Richard I. Sherwood et al. DEVELOPMENTAL DYNAMICS
- -Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of -Cell Mass in Humans
- (2008) J. J. Meier et al. DIABETES
- In Vitro Proliferation of Cells Derived From Adult Human -Cells Revealed By Cell-Lineage Tracing
- (2008) H. A. Russ et al. DIABETES
- Crucial role of insulin receptor substrate-2 in compensatory β-cell hyperplasia in response to high fat diet-induced insulin resistance
- (2008) I. Takamoto et al. DIABETES OBESITY & METABOLISM
- Pancreatic β-cell mass in European subjects with type 2 diabetes
- (2008) J. Rahier et al. DIABETES OBESITY & METABOLISM
- Transcription factor expression in the developing human fetal endocrine pancreas
- (2008) B. M. Lyttle et al. DIABETOLOGIA
- Maturation of Adult β-Cells Revealed Using aPdx1/InsulinDual-Reporter Lentivirus
- (2008) Marta Szabat et al. ENDOCRINOLOGY
- Prolactin Receptor Is Required for Normal Glucose Homeostasis and Modulation of β-Cell Mass during Pregnancy
- (2008) Carol Huang et al. ENDOCRINOLOGY
- Increased pancreatic islet mass is accompanied by activation of the insulin receptor substrate-2/serine-threonine kinase pathway and augmented cyclin D2 protein levels in insulin-resistant rats
- (2008) Alex Rafacho et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- Slow and steady is the key to β-cell replication
- (2008) Kristen Brennand et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- In vivo reprogramming of adult pancreatic exocrine cells to β-cells
- (2008) Qiao Zhou et al. NATURE
- Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
- (2008) Evert Kroon et al. NATURE BIOTECHNOLOGY
- Placental Growth Hormone-Related Proteins and Prolactin-Related Proteins
- (2007) D. Haig PLACENTA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started