Article
Environmental Sciences
Laura Yesenia Castillo, Jorge Rios-Carrillo, Juan Carlos Gonzalez-Orozco, Ignacio Camacho-Arroyo, Jean-Pascal Morin, Rossana C. Zepeda, Gabriel Roldan-Roldan
Summary: This study found that male rats are more susceptible to anxiety induced by BPA exposure during puberty compared to female rats, as evidenced by an increase in passive-coping behaviors and changes in brain gene expression. These findings highlight the importance of considering sex differences in peripubertal behavioral toxicology studies.
Article
Cell Biology
Makoto Sugiyama, Arata Yasunaga, Ryosuke Kobayashi, Hanae Fukasawa, Osamu Hashimoto, Shiro Kurusu, Hiroshi Sasada, Kazuki Yoshioka
Summary: The study demonstrated that re-evaluating and modifying the exfoliative cytology method can accurately identify the pro-estrous stage in mice, with the use of Alcian blue staining showing better results and significantly improving success rates.
CELL AND TISSUE RESEARCH
(2021)
Article
Cardiac & Cardiovascular Systems
Chenchen Zhuang, Guozi Yi, Wenjuan Wang, Runmin Sun, Miaomiao Qi, Jing Yu
Summary: The study found that Sacubitril/valsartan (SAC/VAL) treatment has potential therapeutic effects on improving sexual dysfunction and genital fibrosis in female hypertensive patients. SAC/VAL treatment was more effective than VAL treatment alone, prolonging estrus phase, increasing sexual receptivity and proceptive behaviors, decreasing aggressive behaviors, and improving the fibrosis of vaginal and clitoral tissues.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
(2022)
Article
Psychology, Biological
Cristobal Adrian Dominguez-Estrada, Enrique Hernandez-Arteaga, Abril Zagnitte Gomez-Mendez, Miguel Angel Guevara, Marisela Hernandez-Gonzalez
Summary: Female rats exhibit different behavioral changes and brain functionality during different stages of the estrous cycle, which are influenced by sex hormone levels. This study focused on the attention and EEG activation and coupling between brain regions in female rats during antagonistic phases of the estrous cycle. Results showed that only during the proestrus-estrus phase, females displayed higher attention and greater EEG coupling between medial prefrontal and posterior parietal cortices. This suggests that the functional coupling between these brain regions is important for manifesting proceptivity and receptivity behaviors.
PHYSIOLOGY & BEHAVIOR
(2023)
Article
Endocrinology & Metabolism
Fay A. A. Guarraci, Layla Avendano, Megan Kelly, Cleriza Estoesta, Bernard Sencherey, Hannah S. S. Valdivia, Amanda Gale, Lily Yepez, Jasmine B. B. Belfield, Kristen M. M. Carter, Natalie Williams, Andrea C. C. Gore
Summary: GnRH agonists delay puberty in rats and have different effects on sexual motivation and fertility in females and males.
BIOLOGY OF SEX DIFFERENCES
(2023)
Article
Cell Biology
Yiran Zhou, Han Yan, Wenjun Liu, Chengqing Hu, Yuan Zhou, Ruya Sun, Yida Tang, Chao Zheng, Jichun Yang, Qinghua Cui
Summary: This study provides a comprehensive transcriptomic landscape of female mice during different phases of the reproductive cycle, revealing the widespread regulation of neuro-functions, immune functions, and blood coagulation. The study also identifies key transcription factors and pathways involved in the estrous cycle. Moreover, the study demonstrates the significant impact of the estrous cycle on the cardiovascular system and highlights the enhanced efficacy of certain hypotensive drugs during the estrus phase. Overall, this research contributes valuable insights for investigating the reproductive cycle and precision medicine.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Psychology, Biological
Fay A. Guarraci, Layla Avendano, Megan Kelly, Cleriza Estoesta, Brooke Frohock, Isabel Candelario, Lourdes K. Davis, Matthew Oevermann, Bernard Sencherey, Erin Toro, Hannah S. Valdivia, Andrea C. Gore
Summary: The present study investigated the long-term effects of suppressing puberty with a GnRH agonist in female rats. The results showed that a higher dose of leuprolide acetate significantly delayed puberty in female rats, but had no significant effect on estrous cyclicity and sexual motivation.
PHYSIOLOGY & BEHAVIOR
(2022)
Article
Psychology, Biological
Fay A. Guarraci, Layla Avendano, Megan Kelly, Cleriza Estoesta, Brooke Frohock, Isabel Candelario, Lourdes K. Davis, Matthew Oevermann, Bernard Sencherey, Erin Toro, Hannah S. Valdivia, Andrea C. Gore
Summary: The study found that using a dose of 50 µg/kg of leuprolide significantly delayed puberty in female rats, but did not significantly affect estrous cyclicity or sexual motivation.
PHYSIOLOGY & BEHAVIOR
(2022)
Review
Endocrinology & Metabolism
Marija Kundakovic, Devin Rocks
Summary: This review addresses the increased risk of depression and anxiety disorders in women, focusing on the role of fluctuating sex hormones in brain plasticity and vulnerability. The molecular mechanism driven by sex hormones, namely chromatin organizational changes, is also discussed. Future directions in experimental and clinical studies are highlighted to facilitate innovative approaches in treating depression and anxiety disorders in women.
FRONTIERS IN NEUROENDOCRINOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
I. Rajesh, M. Gobikrushanth, J. E. Carrelli, M. Oba, D. J. Ambrose
Summary: The study aimed to determine the repeatability of anogenital distance (AGD) in different physiological states in cows. The results showed that AGD had high repeatability during the estrous cycle, gestation, and lactation, except during late gestation.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Nutrition & Dietetics
Yaxue Cao, Min Yang, Jie Song, Xuemei Jiang, Shengyu Xu, Lianqiang Che, Zhengfeng Fang, Yan Lin, Chao Jin, Bin Feng, De Wu, Lun Hua, Yong Zhuo
Summary: FGF21, a hormone released in the liver, has been identified as an important endocrine signal for dietary protein intake. This study investigated the role of FGF21 and hypothalamic changes in controlling estrous cyclicity by dietary protein intake. The research found that severe dietary protein restriction resulted in the cessation of estrous cyclicity and ovarian follicle development, and hepatic FGF21 and hypothalamic Kiss-1 were partially required for this process.
Article
Biology
Sara Pagliarani, Chiara Palmieri, Michael McGowan, Frank Carrick, Jackson Boyd, Stephen D. Johnston, Dongbao Chen
Summary: The koala has recently been listed as an endangered species due to challenges associated with habitat fragmentation, climate change, and disease. This article presents the findings of two PhD theses, providing a detailed description of the female koala reproductive anatomy and histology. The research focuses on artificial insemination and the histopathological changes in the urogenital system caused by Chlamydia spp. infections.
Article
Endocrinology & Metabolism
Klaudia Barabas, Gergely Kovacs, Viola Vertes, Erzsebet Kovesdi, Peter Faludi, Ildiko Udvaracz, Daniel Pham, Dora Reglodi, Istvan M. Abraham, Zsuzsanna Nagy
Summary: This study found that embryonic deletion of PACAP significantly alters the structure and function of the GnRH-kisspeptin neuronal network, leading to changes in fertility. Specifically, PACAP KO mice experienced altered estrous cycles with longer periods of diestrus and decreased time in estrus. Furthermore, the number of kisspeptin neurons decreased in the ARC region, while ERα expression levels showed differential changes in different brain regions.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Neurosciences
Luping Yin, Koichi Hashikawa, Yoshiko Hashikawa, Takuya Osakada, Julieta E. Lischinsky, Veronica Diaz, Dayu Lin
Summary: VMHvllCckar cells represent a key neural population that dynamically controls female sexual behaviors over the reproductive cycle.
Article
Multidisciplinary Sciences
Mari Aoki, Igor Gamayun, Amanda Wyatt, Ramona Grunewald, Martin Simon-Thomas, Stephan E. Philipp, Oliver Hummel, Stefan Wagenpfeil, Kathrin Kattler, Gilles Gasparoni, Jorn Walter, Sen Qiao, David R. Grattan, Ulrich Boehm
Summary: The integration between chemosensory cues detected in the nose and hormonal status is not fully understood. However, research on olfactory sensory neurons in mice reveals that the pituitary hormone prolactin can modulate responses to specific chemosensory cues, linking hormonal status with behavioral responses.
Article
Behavioral Sciences
Tania Molina-Jimenez, Liliana Landa-Cadena, Herlinda Bonilla-Jaime
HORMONES AND BEHAVIOR
(2017)
Article
Behavioral Sciences
Carlos M. Contreras, Ana G. Gutierrez-Garcia, Tania Molina-Jimenez
BEHAVIOURAL BRAIN RESEARCH
(2013)
Article
Neurosciences
Carlos M. Contreras, Ana G. Gutierrez-Garcia, Tania Molina-Jimenez, Remedios Mendoza-Lopez
NEUROPSYCHOBIOLOGY
(2012)
Article
Behavioral Sciences
Ana G. Gutierrez-Garcia, Carlos M. Contreras, Diana I. Vasquez-Hernandez, Tania Molina-Jimenez, Emma Jacome-Jacome
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
(2009)
Article
Behavioral Sciences
Tania Molina-Jimenez, Martin Jimenez-Tlapa, Malinalli Brianza-Padilla, Rossana Citlali Zepeda, Marisela Hernandez-Gonzalez, Herlinda Bonilla-Jaime
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
(2019)
Review
Plant Sciences
Claudia Juarez-Portilla, Tatiana Olivares-Banuelos, Tania Molina-Jimenez, Jose Armando Sanchez-Salcedo, Diana Del Moral, Thuluz Meza-Menchaca, Monica Flores-Munoz, Oscar Lopez-Franco, Gabriel Roldan-Roldan, Arturo Ortega, Rossana C. Zepeda
Article
Neurosciences
Ofelia Limon-Morales, Marcela Arteaga-Silva, Julio Cesar Rojas-Castaneda, Tania Molina-Jimenez, Gabriela Veronica Guadarrama-Cruz, Marco Cerbon, Herlinda Bonilla-Jaime
Review
Neurosciences
Oscar Lopez-Franco, Jean-Pascal Morin, Albertina Cortes-Sol, Tania Molina-Jimenez, Diana Del Moral, Monica Flores-Munoz, Gabriel Roldan-Roldan, Claudia Juarez-Portilla, Rossana C. Zepeda
Summary: Hepatic encephalopathy (HE) is a disabling metabolic disease caused by neurotoxins, leading to impaired brain function, with prevalence in cirrhotic patients potentially reaching up to 40%. Recent evidence suggests that cognitive deficits persist in cirrhotic patients with a history of HE even after liver transplant.
FRONTIERS IN NEUROSCIENCE
(2021)
Review
Neurosciences
Herlinda Bonilla-Jaime, Jose Armando Sanchez-Salcedo, M. Maetzi Estevez-Cabrera, Tania Molina-Jimenez, Jose Luis Cortes-Altamirano, Alfonso Alfaro-Rodriguez
Summary: Pain and depression are highly intertwined and may co-exacerbate physical and psychological symptoms. The serotonergic and norepinephrine systems play an important role in this comorbidity. Antidepressants continue to be a major therapeutic tool for managing chronic pain.
CURRENT NEUROPHARMACOLOGY
(2022)
Correction
Neurosciences
Oscar Lopez-Franco, Jean-Pascal Morin, Albertina Cortes-Sol, Tania Molina-Jimenez, Diana I. Del Moral, Monica Flores-Munoz, Gabriel Roldan-Roldan, Claudia Juarez-Portilla, Rossana C. Zepeda
FRONTIERS IN NEUROSCIENCE
(2021)
Editorial Material
Behavioral Sciences
Rossana C. Zepeda, Claudia Juarez-Portilla, Tania Molina-Jimenez
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2023)
Article
Psychiatry
Tania Molina-Jimenez, Ana G. Gutierrez-Garcia, Carlos M. Contreras
Article
Behavioral Sciences
Amine Bahi
Summary: Gestational environmental enrichment (EE) has protective effects on social stress-induced anxiety-like behaviors and excessive ethanol consumption through increasing BDNF levels.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
(2024)
Article
Behavioral Sciences
Sarabesh Natarajan, Grant Abass, Lucas Kim, Corinne Wells, Amir H. Rezvani, Edward D. Levin
Summary: Multiple neural systems, including dopamine D1 receptors and glutamate NMDA receptors, are involved in nicotine reinforcement. Acute blockade of D1 receptors decreases nicotine self-administration, while acute blockade of NMDA receptors increases it. Chronic blockade of NMDA receptors decreases nicotine self-administration. Memantine attenuates the decrease in nicotine self-administration caused by chronic D1 antagonist SCH-23390.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
(2024)
Article
Behavioral Sciences
David R. Maguire
Summary: The study found that Lorcaserin alone reduces ventilation and enhances the ventilatory-depressant effects of opioids. This suggests that combining a 5-HT2C receptor agonist with opioids may increase the risk of ventilatory depression without reducing abuse.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
(2024)
Article
Behavioral Sciences
Fen Liu, Qing Tian, Hui-Ling Tang, Xiang Cheng, Wei Zou, Ping Zhang
Summary: This study demonstrates the attenuating effect of H2S on PD-associated depression by improving hippocampal synaptic plasticity.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
(2024)
Article
Behavioral Sciences
Mehrsa Rahimi-Danesh, Mohammad-Ali Samizadeh, Amir-Ehsan Sajadi, Tara Rezvankhah, Salar Vaseghi
Summary: This study investigated the effects of lithium on freezing behavior and pain perception in a fear-conditioning model in rats. The results showed that lithium had no effect on freezing behavior and pain subthreshold in all rats. Extinction training decreased freezing behavior, with more efficacy in females. Gender differences were also observed in the effects of extinction training.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
(2024)