Chemo-enzymatic synthesis of (E)-2,3-diaryl-5-styryl-trans-2,3-dihydrobenzofuran-based scaffolds and their in vitro and in silico evaluation as a novel sub-family of potential allosteric modulators of the 90 kDa heat shock protein (Hsp90)

The Structural Asymmetry of Mitochondrial Hsp90 (Trap1) Determines Fine Tuning of Functional Dynamics

(2018) Elisabetta Moroni et al.   Journal of Chemical Theory and Computation

Recent trends in fungal laccase for various industrial applications: An eco-friendly approach - A review

(2016) T. Senthivelan et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Synthesis of Functionalized 2-(4-Hydroxyphenyl)-3-methylbenzofuran Allosteric Modulators of Hsp90 Activity

(2016) Sara Sattin et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Laccase-catalyzed dimerization of glycosylated lignols

(2016) Ivan Bassanini et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Insights into the properties of the two enantiomers of trans-δ-viniferin, a resveratrol derivative: antioxidant activity, biochemical and molecular modeling studies of its interactions with hemoglobin

(2016) Silvana Ficarra et al.   Molecular BioSystems

Molecular Dynamics Simulations Reveal the Mechanisms of Allosteric Activation of Hsp90 by Designed Ligands

(2016) Gerolamo Vettoretti et al.   Scientific Reports

Laccase-Catalyzed Dimerization of Piceid, a Resveratrol Glucoside, and its Further Enzymatic Elaboration

(2015) Paolo Gavezzotti et al.   ADVANCED SYNTHESIS & CATALYSIS

Electron transfer and reaction mechanism of laccases

(2015) Stephen M. Jones et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands

(2015) Sara Sattin et al.   CHEMISTRY-A EUROPEAN JOURNAL

Accurate and Reliable Prediction of Relative Ligand Binding Potency in Prospective Drug Discovery by Way of a Modern Free-Energy Calculation Protocol and Force Field

(2015) Lingle Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal-Free Reduction of Aromatic and Aliphatic Nitro Compounds to Amines: A HSiCl3-Mediated Reaction of Wide General Applicability

(2015) M. Orlandi et al.   ORGANIC LETTERS

Chemo-enzymatic synthesis of new resveratrol-related dimers containing the benzo[b]furan framework and evaluation of their radical scavenger activities

(2015) Elisa Beneventi et al.   TETRAHEDRON

PPARα agonists based on stilbene and its bioisosteres: biological evaluation and docking studies

(2015) Barbara De Filippis et al.   MedChemComm

Structural Asymmetry in the Closed State of Mitochondrial Hsp90 (TRAP1) Supports a Two-Step ATP Hydrolysis Mechanism

(2014) Laura A. Lavery et al.   MOLECULAR CELL

Scope and limitations of the Heck–Matsuda-coupling of phenol diazonium salts and styrenes: a protecting-group economic synthesis of phenolic stilbenes

(2013) Bernd Schmidt et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The Quest for New Mild and Selective Modifications of Natural Structures: Laccase-Catalysed Oxidation of Ergot Alkaloids Leads to Unexpected Stereoselective C-4 Hydroxylation

(2012) Cosimo Chirivì et al.   CHEMISTRY-A EUROPEAN JOURNAL

Resveratrol-Related Dehydrodimers: Laccase-Mediated Biomimetic Synthesis and Antiproliferative Activity

(2012) Vedamurthy M. Bhusainahalli et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Heat shock protein 90 in neurodegenerative diseases

(2012) Wenjie Luo et al.   Molecular Neurodegeneration

Corresponding Functional Dynamics across the Hsp90 Chaperone Family: Insights from a Multiscale Analysis of MD Simulations

(2012) Giulia Morra et al.   PLoS Computational Biology

Redox Reactions Catalyzed by Isolated Enzymes

(2011) Daniela Monti et al.   CHEMICAL REVIEWS

Complete NMR data of methoxylated cis- and trans-stilbenes as well as 1,2-diphenylethanes

(2011) Geunhyeong Jo et al.   MAGNETIC RESONANCE IN CHEMISTRY

Conformational dynamics of the molecular chaperone Hsp90

(2011) Kristin A. Krukenberg et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Prediction of Absolute Solvation Free Energies using Molecular Dynamics Free Energy Perturbation and the OPLS Force Field

(2010) Devleena Shivakumar et al.   Journal of Chemical Theory and Computation

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

(2010) Mikko Taipale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hsp90 and Environmental Stress Transform the Adaptive Value of Natural Genetic Variation

(2010) D. F. Jarosz et al.   SCIENCE

Synthetic Applications of Laccase in Green Chemistry

(2009) Suteera Witayakran et al.   ADVANCED SYNTHESIS & CATALYSIS

Laccases: a never-ending story

(2009) Paola Giardina et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

2′-O-Alkyl Derivatives and 5′-Analogues of 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) as Potential Hsp90 Inhibitors

(2009) Antonio Bracci et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Laccase-mediated oxidation of phenolic derivatives

(2009) Cristina Navarra et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Designer laccases: a vogue for high-potential fungal enzymes?

(2009) Caroline J. Rodgers et al.   TRENDS IN BIOTECHNOLOGY

Laccase-catalyzed coupling of catharanthine and vindoline: an efficient approach to the bisindole alkaloid anhydrovinblastine

(2008) Francesca Sagui et al.   TETRAHEDRON