Conformational dynamics of the molecular chaperone Hsp90

Asymmetric Activation of the Hsp90 Dimer by Its Cochaperone Aha1

(2010) Marco Retzlaff et al.   MOLECULAR CELL

Swe1Wee1-Dependent Tyrosine Phosphorylation of Hsp90 Regulates Distinct Facets of Chaperone Function

(2010) Mehdi Mollapour et al.   MOLECULAR CELL

Mechanistic Studies of Sansalvamide A-Amide: An Allosteric Modulator of Hsp90

(2010) Robert C. Vasko et al.   ACS Medicinal Chemistry Letters

Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine

(2009) Christian Graf et al.   EMBO JOURNAL

The Molecular Chaperone Hsp90 Modulates Intermediate Steps of Amyloid Assembly of the Parkinson-related Protein α-Synuclein

(2009) S. Fabio Falsone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HDAC6 Modulates Hsp90 Chaperone Activity and Regulates Activation of Aryl Hydrocarbon Receptor Signaling

(2009) Vikram D. Kekatpure et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

pH-Dependent Conformational Changes in Bacterial Hsp90 Reveal a Grp94-Like Conformation at pH 6 That Is Highly Active in Suppression of Citrate Synthase Aggregation

(2009) Kristin A. Krukenberg et al.   JOURNAL OF MOLECULAR BIOLOGY

Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90

(2009) Martin Hessling et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Grp94, the endoplasmic reticulum Hsp90, has a similar solution conformation to cytosolic Hsp90 in the absence of nucleotide

(2009) Kristin A. Krukenberg et al.   PROTEIN SCIENCE

Modeling Signal Propagation Mechanisms and Ligand-Based Conformational Dynamics of the Hsp90 Molecular Chaperone Full-Length Dimer

(2009) Giulia Morra et al.   PLoS Computational Biology

Drug–target identification from total cellular lysate by drug-induced conformational changes

(2008) Yoichi Nishiya et al.   ANALYTICAL BIOCHEMISTRY

Analysis of Hsp90 Cochaperone Interactions Reveals a Novel Mechanism for TPR Protein Recognition†

(2008) Ahmed Chadli et al.   BIOCHEMISTRY

Plasticity of the Hsp90 chaperone machine in divergent eukaryotic organisms

(2008) Jill L. Johnson et al.   CELL STRESS & CHAPERONES

Phase II Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Metastatic Melanoma

(2008) D. B. Solit et al.   CLINICAL CANCER RESEARCH

The ATPase Cycle of the Mitochondrial Hsp90 Analog Trap1

(2008) Adriane Leskovar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intra- and Intermonomer Interactions Are Required to Synergistically Facilitate ATP Hydrolysis in Hsp90

(2008) Christian N. Cunningham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Hsp90 Chaperone Machinery

(2008) Sebastian Karl Wandinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Studies on the Co-chaperone Hop and Its Complexes with Hsp90

(2008) S.C. Onuoha et al.   JOURNAL OF MOLECULAR BIOLOGY

Species-Dependent Ensembles of Conserved Conformational States Define the Hsp90 Chaperone ATPase Cycle

(2008) Daniel R. Southworth et al.   MOLECULAR CELL

Akt and CHIP coregulate tau degradation through coordinated interactions

(2008) C. A. Dickey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple Conformations of E. coli Hsp90 in Solution: Insights into the Conformational Dynamics of Hsp90

(2008) Kristin A. Krukenberg et al.   STRUCTURE