FGFR2 regulates Mre11 expression and double-strand break repair via the MEK-ERK-POU1F1 pathway in breast tumorigenesis
出版年份 2015 全文链接
标题
FGFR2 regulates Mre11 expression and double-strand break repair via the MEK-ERK-POU1F1 pathway in breast tumorigenesis
作者
关键词
-
出版物
HUMAN MOLECULAR GENETICS
Volume 24, Issue 12, Pages 3506-3517
出版商
Oxford University Press (OUP)
发表日期
2015-03-19
DOI
10.1093/hmg/ddv102
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium
- (2014) D Agarwal et al. BRITISH JOURNAL OF CANCER
- Fine-Scale Mapping of the FGFR2 Breast Cancer Risk Locus: Putative Functional Variants Differentially Bind FOXA1 and E2F1
- (2013) Kerstin B. Meyer et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Beyond GWASs: Illuminating the Dark Road from Association to Function
- (2013) Stacey L. Edwards et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A novel estrogen receptor-microRNA 190a-PAR-1-pathway regulates breast cancer progression, a finding initially suggested by genome-wide analysis of loci associated with lymph-node metastasis
- (2013) Hou-Wei Chu et al. HUMAN MOLECULAR GENETICS
- DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
- (2013) Atsushi Shibata et al. MOLECULAR CELL
- Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients
- (2012) Balázs Győrffy et al. ENDOCRINE-RELATED CANCER
- The Breast Cancer Susceptibility Gene Product Fibroblast Growth Factor Receptor 2 Serves as a Scaffold for Regulation of NF- B Signaling
- (2012) W. Wei et al. MOLECULAR AND CELLULAR BIOLOGY
- Playing the End Game: DNA Double-Strand Break Repair Pathway Choice
- (2012) J. Ross Chapman et al. MOLECULAR CELL
- The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
- (2012) Christina Curtis et al. NATURE
- EPD and EPDnew, high-quality promoter resources in the next-generation sequencing era
- (2012) René Dreos et al. NUCLEIC ACIDS RESEARCH
- FGFR2 Point Mutations in 466 Endometrioid Endometrial Tumors: Relationship with MSI, KRAS, PIK3CA, CTNNB1 Mutations and Clinicopathological Features
- (2012) Sara A. Byron et al. PLoS One
- Double-Strand Break End Resection and Repair Pathway Choice
- (2011) Lorraine S. Symington et al. Annual Review of Genetics
- Overexpressed fibroblast growth factor receptor 2 in the invasive front of colorectal cancer: A potential therapeutic target in colorectal cancer
- (2011) Yoko Matsuda et al. CANCER LETTERS
- MRE11 Deficiency Increases Sensitivity to Poly(ADP-ribose) Polymerase Inhibition in Microsatellite Unstable Colorectal Cancers
- (2011) E. Vilar et al. CANCER RESEARCH
- Current status of genome-wide association studies in cancer
- (2011) Charles C. Chung et al. HUMAN GENETICS
- The MRE11 complex: starting from the ends
- (2011) Travis H. Stracker et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Phosphorylation and Activation of Cell Division Cycle Associated 5 by Mitogen-Activated Protein Kinase Play a Crucial Role in Human Lung Carcinogenesis
- (2010) M.-H. Nguyen et al. CANCER RESEARCH
- GP369, an FGFR2-IIIb-Specific Antibody, Exhibits Potent Antitumor Activity against Human Cancers Driven by Activated FGFR2 Signaling
- (2010) A. Bai et al. CANCER RESEARCH
- A role for ATM kinase activity and Mre11 in microhomology-mediated end-joining
- (2010) Anthony J. Davis et al. CELL CYCLE
- Poly(ADP-Ribose) Polymerase 1 Modulates the Lethality of CHK1 Inhibitors in Carcinoma Cells
- (2010) C. Mitchell et al. MOLECULAR PHARMACOLOGY
- The Pit-1/Pou1f1 transcription factor regulates and correlates with prolactin expression in human breast cell lines and tumors
- (2009) I Ben-Batalla et al. ENDOCRINE-RELATED CANCER
- FGFR2 Abnormalities Underlie a Spectrum of Bone, Skin, and Cancer Pathologies
- (2009) Masaru Katoh JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The DNA-damage response in human biology and disease
- (2009) Stephen P. Jackson et al. NATURE
- FGFR2 Is a Breast Cancer Susceptibility Gene in Jewish and Arab Israeli Populations
- (2008) L. Raskin et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- FGFR2-Amplified Gastric Cancer Cell Lines Require FGFR2 and Erbb3 Signaling for Growth and Survival
- (2008) K. Kunii et al. CANCER RESEARCH
- Hormone-dependent effects of FGFR2 and MAP3K1 in breast cancer susceptibility in a population-based sample of post-menopausal African-American and European-American women
- (2008) T. R. Rebbeck et al. CARCINOGENESIS
- Genetic variants in fibroblast growth factor receptor 2 (FGFR2) contribute to susceptibility of breast cancer in Chinese women
- (2008) J. Liang et al. CARCINOGENESIS
- Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair
- (2008) Wen-Cheng Chou et al. EMBO JOURNAL
- Mre11–Rad50–Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity
- (2008) Ali Jazayeri et al. EMBO JOURNAL
- Regulation of DNA repair throughout the cell cycle
- (2008) Dana Branzei et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Allele-Specific Up-Regulation of FGFR2 Increases Susceptibility to Breast Cancer
- (2008) Kerstin B Meyer et al. PLOS BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now