Glucocerebrosidase deficiency accelerates the accumulation of proteinase K-resistant α-synuclein and aggravates neurodegeneration in aDrosophilamodel of Parkinson's disease
出版年份 2015 全文链接
标题
Glucocerebrosidase deficiency accelerates the accumulation of proteinase K-resistant α-synuclein and aggravates neurodegeneration in aDrosophilamodel of Parkinson's disease
作者
关键词
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出版物
HUMAN MOLECULAR GENETICS
Volume 24, Issue 23, Pages 6675-6686
出版商
Oxford University Press (OUP)
发表日期
2015-09-12
DOI
10.1093/hmg/ddv372
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Augmentation of phenotype in a transgenic Parkinson mouse heterozygous for a Gaucher mutation
- (2014) Ianai Fishbein et al. BRAIN
- iPSC-derived neurons from GBA1-associated Parkinson’s disease patients show autophagic defects and impaired calcium homeostasis
- (2014) David C. Schöndorf et al. Nature Communications
- Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons
- (2013) Jing L. Guo et al. CELL
- Neuronal accumulation of glucosylceramide in a mouse model of neuronopathic Gaucher disease leads to neurodegeneration
- (2013) T. Farfel-Becker et al. HUMAN MOLECULAR GENETICS
- Advances in the genetics of Parkinson disease
- (2013) Joanne Trinh et al. Nature Reviews Neurology
- Unfolded protein response in Gaucher disease: from human to Drosophila
- (2013) Gali Maor et al. Orphanet Journal of Rare Diseases
- Loss of β-Glucocerebrosidase Activity Does Not Affect Alpha-Synuclein Levels or Lysosomal Function in Neuronal Cells
- (2013) Georgia Dermentzaki et al. PLoS One
- Expression of Human Gaucher Disease Gene GBA Generates Neurodevelopmental Defects and ER Stress in Drosophila Eye
- (2013) Takahiro Suzuki et al. PLoS One
- Structural and functional characterization of two alpha-synuclein strains
- (2013) Luc Bousset et al. Nature Communications
- A Multicenter Study of Glucocerebrosidase Mutations in Dementia With Lewy Bodies
- (2013) Michael A. Nalls et al. JAMA Neurology
- Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains
- (2012) Matthew E. Gegg et al. ANNALS OF NEUROLOGY
- Ambroxol as a pharmacological chaperone for mutant glucocerebrosidase
- (2012) Inna Bendikov-Bar et al. BLOOD CELLS MOLECULES AND DISEASES
- Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein
- (2012) Nunilo Cremades et al. CELL
- Glucocerebrosidase Mutations alter the endoplasmic reticulum and lysosomes in Lewy body disease
- (2012) Marzena Kurzawa-Akanbi et al. JOURNAL OF NEUROCHEMISTRY
- Accumulation of Toxic -Synuclein Oligomer within Endoplasmic Reticulum Occurs in -Synucleinopathy In Vivo
- (2012) E. Colla et al. JOURNAL OF NEUROSCIENCE
- Endoplasmic Reticulum Stress Is Important for the Manifestations of -Synucleinopathy In Vivo
- (2012) E. Colla et al. JOURNAL OF NEUROSCIENCE
- Increased dimerization of alpha-synuclein in erythrocytes in Gaucher disease and aging
- (2012) Assimina Argyriou et al. NEUROSCIENCE LETTERS
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- Acid β-glucosidase mutants linked to gaucher disease, parkinson disease, and lewy body dementia alter α-synuclein processing
- (2011) Valerie Cullen et al. ANNALS OF NEUROLOGY
- Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies
- (2011) Joseph R. Mazzulli et al. CELL
- Glucosylceramide synthase in the fat body controls energy metabolism inDrosophila
- (2011) Ayako Kohyama-Koganeya et al. JOURNAL OF LIPID RESEARCH
- Improved Immunodetection of Endogenous α-Synuclein
- (2011) Byung Rho Lee et al. PLoS One
- Proteinase K-resistant α-synuclein is deposited in presynapses in human Lewy body disease and A53T α-synuclein transgenic mice
- (2010) Kunikazu Tanji et al. ACTA NEUROPATHOLOGICA
- Cerebroside-β-glucosidase activity in Gaucher brain
- (2010) Lars Svennerholm et al. CLINICAL GENETICS
- Lysosomal Degradation of α-Synucleinin Vivo
- (2010) Sally K. Mak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The risk of Parkinson’s disease in type 1 Gaucher disease
- (2010) Gilberto Bultron et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson’s disease
- (2010) Arianna Bellucci et al. JOURNAL OF NEUROCHEMISTRY
- Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease
- (2009) Juliane Neumann et al. BRAIN
- Ubiquitin Carboxyl-Terminal Hydrolase L3 Promotes Insulin Signaling and Adipogenesis
- (2009) Mari Suzuki et al. ENDOCRINOLOGY
- Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
- (2009) Wataru Satake et al. NATURE GENETICS
- Genome-wide association study reveals genetic risk underlying Parkinson's disease
- (2009) Javier Simón-Sánchez et al. NATURE GENETICS
- Alpha-synuclein-glucocerebrosidase interactions in pharmacological Gaucher models: A biological link between Gaucher disease and parkinsonism
- (2009) Amy B. Manning-Boğ et al. NEUROTOXICOLOGY
- Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease
- (2009) E. Sidransky et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inclusion formation and neuronal cell death through neuron-to-neuron transmission of -synuclein
- (2009) P. Desplats et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells
- (2008) Tereza Vogiatzi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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