Article
Peripheral Vascular Disease
So-Ryoung Lee, Kyung-Do Han, Eue-Keun Choi, Hyo-Jeong Ahn, Seil Oh, Gregory Y. H. Lip
Summary: The study found that in young adults, stage 1 isolated diastolic hypertension and isolated systolic hypertension were associated with a higher risk of incident atrial fibrillation compared to normal blood pressure, while stage 2 hypertension (including diastolic, systolic, and systolic-diastolic combined) was associated with even higher risks of atrial fibrillation.
Article
Cardiac & Cardiovascular Systems
Nathan K. Itoga, Daniel S. Taw, Maria E. Montez-Rath, Tara I. Chang
Summary: The study found that there are differences in the risk pattern of systolic blood pressure (SBP) and diastolic blood pressure (DBP) depending on clinical outcomes, with different SBP and DBP ranges associated with the lowest risk for different cardiovascular events. This suggests that individualization of blood pressure targets may be necessary based on the specific cardiovascular event for which a patient is most at risk.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Geriatrics & Gerontology
Sibo Liu, Mengxing Wang, Dean Gu, Yanzhao Li, Xin Zhang, Hang Li, Chenhua Ji, Ximing Nie, Jinjie Liu
Summary: This study investigated the optimal control thresholds for systolic and diastolic blood pressure in patients with white matter hyperintensity (WMH). The results showed that both SBP and DBP were strongly associated with the severity of WMH. A target mean SBP below 130 mmHg and mean DBP below 80 mmHg were associated with a lower risk of WMH progression.
FRONTIERS IN AGING NEUROSCIENCE
(2023)
Article
Clinical Neurology
Yohwan Lim, Bo Chang Kim, Sung Soo Yoon, Hye Jun Kim, Sang Jun Lee, Myeong Hoon Lee, Ju Hee Kim, Sun Jae Park, Seogsong Jeong, Hyun Wook Han
Summary: This study investigates the association between changes in blood pressure (systolic and diastolic) and incident depression. Analysis of 224,192 participants reveals that individuals who experienced a decrease in systolic blood pressure from above 140 mmHg to 120-129 mmHg, as well as a decrease in diastolic blood pressure from above 90 mmHg to 60-79 mmHg, have a higher risk of developing depression.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Biochemistry & Molecular Biology
Tomislav Bulum, Martina Tomic, Romano Vrabec, Neva Brkljacic, Spomenka Ljubic
Summary: This study investigated the risk factors for diabetic retinopathy (DR) in patients with type 2 diabetes (T2DM) with and without diabetic nephropathy (DN). The main predictors of DR in patients with T2DM were found to be diabetes duration, glycemic control (HbA1c), and systolic and diastolic blood pressure. The influence of blood pressure on DR development remained significant even after adjusting for diabetes duration and HbA1c.
Article
Nutrition & Dietetics
Nives Bogataj Jontez, Sasa Kenig, Karin Sik Novak, Ana Petelin, Zala Jenko Praznikar, Nina Mohorko
Summary: This study compared the dietary patterns of individuals following LCHF, vegan, vegetarian, and omnivorous diets. The results showed that compared to other groups, the LCHF group had higher intakes of saturated fats, cholesterol, and animal proteins, while the intakes of sugars and dietary fibers were lower. The levels of total and LDL cholesterol were significantly higher in the LCHF group. Thus, it is recommended to select healthy fat sources, increase dietary fiber intake, and partially replace animal sources with plant sources in the LCHF diet.
FRONTIERS IN NUTRITION
(2023)
Article
Nutrition & Dietetics
Philip J. Prins, Timothy D. Noakes, Alex Buga, Dominic P. D'Agostino, Jeff S. Volek, Jeffrey D. Buxton, Kara Heckman, Dalton W. Jones, Naomi E. Tobias, Holly M. Grose, Anna K. Jenkins, Kelli T. Jancay, Andrew P. Koutnik
Summary: Recent research challenges the notion that high carbohydrate, low fat (HCLF) diets are superior for athletic performance and highlights the potential health benefits of low carbohydrate, high fat (LCHF) diets. In this study, highly trained competitive middle-aged athletes followed either a HCLF or LCHF diet for 31 days and found that there were no significant differences in performance, body composition, or metabolic markers between the two groups. However, the LCHF diet resulted in higher rates of fat oxidation and improved glycemic control, especially in individuals at risk for diabetes.
FRONTIERS IN NUTRITION
(2023)
Article
Engineering, Biomedical
Branko G. Celler, Mark Butlin, Ahmadreza Argha, Isabella Tan, Andy Yong, Alberto Avolio
Summary: Non-invasive blood pressure measurements often underestimate systolic blood pressure and overestimate diastolic blood pressure. The study found that Korotkoff sounds accurately detect the onset of blood flow and closely coincide with diastolic blood pressure.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2021)
Article
Genetics & Heredity
Nhu Ngoc Le, Tran Q. B. Tran, Stefanie Lip, Linsay McCallum, John McClure, Anna F. Dominiczak, Dipender Gill, Sandosh Padmanabhan
Summary: The genetic predisposition to high systolic blood pressure is associated with an increased risk of cardiovascular diseases such as coronary artery disease, stroke, heart failure, atrial fibrillation, and type 2 diabetes mellitus. Similarly, genetic predisposition to high diastolic blood pressure is associated with an increased risk of stroke and coronary artery disease.
Review
Nutrition & Dietetics
Piotr Machowiec, Gabriela Reka, Marcela Maksymowicz, Halina Piecewicz-Szczesna, Agata Smolen
Summary: The study found that supplementation of Spirulina can significantly lower diastolic and systolic blood pressure, especially among hypertensive patients. This suggests that Spirulina administration may have a positive impact on the prevention and treatment of hypertension. Further, more precise randomized controlled trials are needed to confirm the effects of Spirulina supplementation on blood pressure.
Article
Peripheral Vascular Disease
Yukako Tatsumi, Michihiro Satoh, Kei Asayama, Takahisa Murakami, Takuo Hirose, Azusa Hara, Megumi Tsubota-Utsugi, Ryusuke Inoue, Masahiro Kikuya, Kyoko Nomura, Hirohito Metoki, Atsushi Hozawa, Hideki Katagiri, Yutaka Imai, Takayoshi Ohkubo
Summary: This study investigated the association between different hypertension subtypes and glucose metabolism among the Japanese population, and found that participants with evening hypertension subtype and office blood pressure hypertension subtype had higher blood glucose levels and insulin resistance compared to those with normal blood pressure, highlighting the importance of measuring evening blood pressure and office blood pressure for early detection of hypertension and diabetes.
JOURNAL OF HYPERTENSION
(2022)
Article
Peripheral Vascular Disease
Odayme Quesada, Brian Claggett, Fatima Rodriguez, Jianwen Cai, Ashley E. Moncrieft, Karin Garcia, Marina Del Rios Rivera, David B. Hanna, Martha L. Daviglus, Gregory A. Talavera, C. Noel Bairey Merz, Scott D. Solomon, Susan Cheng, Natalie A. Bello
Summary: In a study of Hispanic/Latino adults without diabetes or taking antihypertensive medications, insulin resistance was found to be positively associated with both systolic and diastolic blood pressure. The association between insulin resistance and systolic blood pressure was linear in men but nonlinear in women. Prediabetes status did not significantly affect the association between insulin resistance and blood pressure.
Article
Peripheral Vascular Disease
Tanika N. Kelly, Xiao Sun, Karen Y. He, Michael R. Brown, Sarah A. Gagliano Taliun, Jacklyn N. Hellwege, Marguerite R. Irvin, Xuenan Mi, Jennifer A. Brody, Nora Franceschini, Xiuqing Guo, Shih-Jen Hwang, Paul S. de Vries, Yan Gao, Arden Moscati, Girish N. Nadkarni, Lisa R. Yanek, Tali Elfassy, Jennifer A. Smith, Ren-Hua Chung, Amber L. Beitelshees, Amit Patki, Stella Aslibekyan, Brandon M. Blobner, Juan M. Peralta, Themistocles L. Assimes, Walter R. Palmas, Chunyu Liu, Adam P. Bress, Zhijie Huang, Lewis C. Becker, Chii-Min Hwa, Jeffrey R. O'Connell, Jenna C. Carlson, Helen R. Warren, Sayantan Das, Ayush Giri, Lisa W. Martin, W. Craig Johnson, Ervin R. Fox, Erwin P. Bottinger, Alexander C. Razavi, Dhananjay Vaidya, Lee-Ming Chuang, Yen-Pei C. Chang, Take Naseri, Deepti Jain, Hyun Min Kang, Adriana M. Hung, Vinodh Srinivasasainagendra, Beverly M. Snively, Dongfeng Gu, May E. Montasser, Muagututi'a Sefuiva Reupena, Benjamin D. Heavner, Jonathon LeFaive, James E. Hixson, Kenneth M. Rice, Fei Fei Wang, Jonas B. Nielsen, Jianfeng Huang, Alyna T. Khan, Wei Zhou, Jovia L. Nierenberg, Cathy C. Laurie, Nicole D. Armstrong, Mengyao Shi, Yang Pan, Adrienne M. Stilp, Leslie Emery, Quenna Wong, Nicola L. Hawley, Ryan L. Minster, Joanne E. Curran, Patricia B. Munroe, Daniel E. Weeks, Kari E. North, Russell P. Tracy, Eimear E. Kenny, Daichi Shimbo, Aravinda Chakravarti, Stephen S. Rich, Alex P. Reiner, John Blangero, Susan Redline, Braxton D. Mitchell, Dabeeru C. Rao, Yii-Der Ida Chen, Sharon L. R. Kardia, Robert C. Kaplan, Rasika A. Mathias, Jiang He, Bruce M. Psaty, Myriam Fornage, Ruth J. F. Loos, Adolfo Correa, Eric Boerwinkle, Jerome I. Rotter, Charles Kooperberg, Todd L. Edwards, Goncalo R. Abecasis, Xiaofeng Zhu, Daniel Levy, Donna K. Arnett, Alanna C. Morrison
Summary: This study conducted a multiancestry whole-genome sequencing analysis to explore the associations between coding and noncoding variants and blood pressure. The study identified two significant blood pressure signals and nineteen suggestive signals, providing insights for future blood pressure sequencing studies, including the use of aggregate analyses and the need for larger, diverse samples and family studies.
Article
Peripheral Vascular Disease
Atefeh Talebi, Rikke Normark Mortensen, Thomas Alexander Gerds, Jorgen Lykke Jeppesen, Christian Torp-Pedersen
Summary: The study found that adding systolic blood pressure, whether from office or 24-hour ambulatory monitoring, did not significantly improve the predictive ability for cardiovascular mortality and events. Additionally, office blood pressure did not provide additional prognostic information compared to diastolic pressure within a 10-year timeframe.
JOURNAL OF CLINICAL HYPERTENSION
(2022)
Article
Peripheral Vascular Disease
Saeed Shihab, Robert E. Boucher, Nikita Abraham, Guo Wei, Srinivasan Beddhu
Summary: The study aimed to investigate whether lowering systolic blood pressure would increase the risk of stroke in individuals with low baseline diastolic blood pressure. The results showed that intensive systolic control did not appear to increase the risk of stroke in this population. This finding is clinically significant for guiding practice.