Apigenin, a dietary flavonoid, induces apoptosis, DNA damage, and oxidative stress in human breast cancer MCF-7 and MDA MB-231 cells
出版年份 2018 全文链接
标题
Apigenin, a dietary flavonoid, induces apoptosis, DNA damage, and oxidative stress in human breast cancer MCF-7 and MDA MB-231 cells
作者
关键词
Apigenin, Breast cancer cells, Human lymphocytes, Cytogenotoxicity, Apoptosis, Anticancer effect
出版物
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Volume 391, Issue 5, Pages 537-550
出版商
Springer Nature
发表日期
2018-03-14
DOI
10.1007/s00210-018-1486-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Apigenin: A dietary flavonoid with diverse anticancer properties
- (2018) Josip Madunić et al. CANCER LETTERS
- Cytochrome P450 CYP1 metabolism of hydroxylated flavones and flavonols: Selective bioactivation of luteolin in breast cancer cells
- (2017) Nicola E. Wilsher et al. FOOD AND CHEMICAL TOXICOLOGY
- Apigenin inhibits proliferation and invasion, and induces apoptosis and cell cycle arrest in human melanoma cells
- (2017) Guangming Zhao et al. ONCOLOGY REPORTS
- Inhibition of MDA-MB-231 breast cancer cell proliferation and tumor growth by apigenin through induction of G2/M arrest and histone H3 acetylation-mediated p21WAF1/CIP1expression
- (2016) Tsui-Hwa Tseng et al. ENVIRONMENTAL TOXICOLOGY
- Role of dietary bioactive natural products in estrogen receptor-positive breast cancer
- (2016) Min Ji Bak et al. SEMINARS IN CANCER BIOLOGY
- Natural Polyphenols for Prevention and Treatment of Cancer
- (2016) Yue Zhou et al. Nutrients
- The Anti-Cancer Effect of Polyphenols against Breast Cancer and Cancer Stem Cells: Molecular Mechanisms
- (2016) Ahmed Abdal Dayem et al. Nutrients
- Lead Phytochemicals for Anticancer Drug Development
- (2016) Sukhdev Singh et al. Frontiers in Plant Science
- Nutrition, aging and cancer: lessons from dietary intervention studies
- (2016) Giuseppe Carruba et al. Immunity & Ageing
- Apigenin potentiates TRAIL therapy of non-small cell lung cancer via upregulating DR4/DR5 expression in a p53-dependent manner
- (2016) Minghui Chen et al. Scientific Reports
- Apigenin and Breast Cancers: From Chemistry to Medicine
- (2015) Seyed Nabavi et al. Anti-Cancer Agents in Medicinal Chemistry
- Induction of caspase-dependent extrinsic apoptosis by apigenin through inhibition of signal transducer and activator of transcription 3 (STAT3) signalling in HER2-overexpressing BT-474 breast cancer cells
- (2015) H.-S. Seo et al. BIOSCIENCE REPORTS
- Flavones inhibit breast cancer proliferation through the Akt/FOXO3a signaling pathway
- (2015) Chia-Hung Lin et al. BMC CANCER
- Apigenin induces caspase-dependent apoptosis by inhibiting signal transducer and activator of transcription 3 signaling in HER2-overexpressing SKBR3 breast cancer cells
- (2015) HYE-SOOK SEO et al. Molecular Medicine Reports
- Apigenin induced apoptosis in esophageal carcinoma cells by destruction membrane structures
- (2015) Haiyan Zhu et al. SCANNING
- Quantification of malondialdehyde by HPLC-FL - application to various biological samples
- (2014) Ana-Marija Domijan et al. BIOMEDICAL CHROMATOGRAPHY
- The differential susceptibilities of MCF-7 and MDA-MB-231 cells to the cytotoxic effects of curcumin are associated with the PI3K/Akt-SKP2-Cip/Kips pathway
- (2014) Tao Jia et al. Cancer Cell International
- Exposure of breast cancer cells to a subcytotoxic dose of apigenin causes growth inhibition, oxidative stress, and hypophosphorylation of Akt
- (2014) Megan E. Harrison et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Apigenin Induces the Apoptosis and Regulates MAPK Signaling Pathways in Mouse Macrophage ANA-1 Cells
- (2014) Yuexia Liao et al. PLoS One
- Apigenin induced MCF-7 cell apoptosis-associated reactive oxygen species
- (2014) Haihua Bai et al. SCANNING
- Cruciferous Vegetables: Dietary Phytochemicals for Cancer Prevention
- (2013) Ahmad Faizal Abdull Razis et al. Asian Pacific Journal of Cancer Prevention
- Physico-chemical characterization and the in vitro genotoxicity of medical implants metal alloy (TiAlV and CoCrMo) and polyethylene particles in human lymphocytes
- (2013) Goran Gajski et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Apigenin shows synergistic anticancer activity with curcumin by binding at different sites of tubulin
- (2013) Diptiman Choudhury et al. BIOCHIMIE
- Flavonoids as prospective compounds for anti-cancer therapy
- (2013) Divyashree Ravishankar et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Patterns of Recurrence and Outcome According to Breast Cancer Subtypes in Lymph Node–Negative Disease: Results From International Breast Cancer Study Group Trials VIII and IX
- (2013) Otto Metzger-Filho et al. JOURNAL OF CLINICAL ONCOLOGY
- Modulation of radiation-induced and mitomycin C-induced chromosome damage by apigenin in human lymphocytes in vitro
- (2013) Narinder K. Sharma JOURNAL OF RADIATION RESEARCH
- Effects of Dietary Apigenin on Tumor Latency, Incidence and Multiplicity in a Medroxyprogesterone Acetate- Accelerated 7,12-Dimethylbenz(a)anthracene- Induced Breast Cancer Model
- (2013) Benford Mafuvadze et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Herbacetin, A Constituent of Ephedrae herba, Suppresses the HGF-Induced Motility of Human Breast Cancer MDA-MB-231 Cells by Inhibiting c-Met and Akt Phosphorylation
- (2013) Sumiko Hyuga et al. PLANTA MEDICA
- Molecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets
- (2013) D. Arango et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Apigenin induces DNA damage through the PKCδ-dependent activation of ATM and H2AX causing down-regulation of genes involved in cell cycle control and DNA repair
- (2012) Daniel Arango et al. BIOCHEMICAL PHARMACOLOGY
- A Prooxidant Mechanism for the Anticancer and Chemopreventive Properties of Plant Polyphenols
- (2012) Husain Yar Khan et al. CURRENT DRUG TARGETS
- Apigenin ameliorates gamma radiation-induced cytogenetic alterations in cultured human blood lymphocytes
- (2012) Naziya Begum et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- Evidence for activation of mutated p53 by apigenin in human pancreatic cancer
- (2011) Jonathan C. King et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Apoptotic Effects of Genistein, Biochanin-A and Apigenin on LNCaP and PC-3 Cells by p21 through Transcriptional Inhibition of Polo-like Kinase-1
- (2011) Young Jin Seo et al. JOURNAL OF KOREAN MEDICAL SCIENCE
- Apigenin Induces Apoptosis in Human Leukemia Cells and Exhibits Anti-Leukemic Activity In Vivo
- (2011) A. Budhraja et al. MOLECULAR CANCER THERAPEUTICS
- Triple-Negative Breast Cancer: An Unmet Medical Need
- (2011) C. A. Hudis et al. ONCOLOGIST
- Spectrophotometric analysis of flavonoid-DNA interactions and DNA damaging/protecting and cytotoxic potential of flavonoids in human peripheral blood lymphocytes
- (2010) Gordana Rusak et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Anticlastogenic effect of apigenin in human lymphocytes treated with ethinylestradiol
- (2010) Yasir Hasan Siddique et al. FITOTERAPIA
- Apigenin induces apoptosis in human lung cancer H460 cells through caspase- and mitochondria-dependent pathways
- (2010) Hsu-Feng Lu et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Protoapigenone, a natural derivative of apigenin, induces mitogen-activated protein kinase-dependent apoptosis in human breast cancer cells associated with induction of oxidative stress and inhibition of glutathione S-transferase π
- (2010) Wen-Ying Chen et al. INVESTIGATIONAL NEW DRUGS
- Apigenin: A Promising Molecule for Cancer Prevention
- (2010) Sanjeev Shukla et al. PHARMACEUTICAL RESEARCH
- Evaluation of the Cytogenetic Status of Human Lymphocytes After Exposure to a High Concentration of Bee Venom In Vitro
- (2009) Verica Garaj-Vrhovac et al. Arhiv za Higijenu Rada i Toksikologiju-Archives of Industrial Hygiene and Toxicology
- Biology, Metastatic Patterns, and Treatment of Patients with Triple-Negative Breast Cancer
- (2009) Carey K. Anders et al. Clinical Breast Cancer
- 5-Fluorouracil combined with apigenin enhances anticancer activity through induction of apoptosis in human breast cancer MDA-MB-453 cells
- (2009) Choi ONCOLOGY REPORTS
- Apigenin-induced prostate cancer cell death is initiated by reactive oxygen species and p53 activation
- (2008) Sanjeev Shukla et al. FREE RADICAL BIOLOGY AND MEDICINE
- Apigenin causes G2/M arrest associated with the modulation of p21Cip1 and Cdc2 and activates p53-dependent apoptosis pathway in human breast cancer SK-BR-3 cells
- (2008) Eun Jeong Choi et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Apigenin inhibits antiestrogen-resistant breast cancer cell growth through estrogen receptor- -dependent and estrogen receptor- -independent mechanisms
- (2008) X. Long et al. MOLECULAR CANCER THERAPEUTICS
- Phytochemistry and pharmacogenomics of natural products derived from traditional chinese medicine and chinese materia medica with activity against tumor cells
- (2008) T. Efferth et al. MOLECULAR CANCER THERAPEUTICS
- Cancer is a Preventable Disease that Requires Major Lifestyle Changes
- (2008) Preetha Anand et al. PHARMACEUTICAL RESEARCH
- Apigenin inhibits HGF-promoted invasive growth and metastasis involving blocking PI3K/Akt pathway and β4 integrin function in MDA-MB-231 breast cancer cells
- (2007) Wei-Jiunn Lee et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
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