Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza

Influenza lung injury: mechanisms and therapeutic opportunities

(2015) David J. Gregory et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Neutrophil trails guide influenza-specific CD8+ T cells in the airways

(2015) K. Lim et al.   SCIENCE

Accumulation of Human-Adapting Mutations during Circulation of A(H1N1)pdm09 Influenza Virus in Humans in the United Kingdom

(2014) R. A. Elderfield et al.   JOURNAL OF VIROLOGY

Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

(2014) Katrin D. Mayer-Barber et al.   NATURE

Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression

(2014) Netanya G. Sandler et al.   NATURE

The application of transcriptional blood signatures to enhance our understanding of the host response to infection: the example of tuberculosis

(2014) S. Blankley et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Pathogenic potential of interferon αβ in acute influenza infection

(2014) Sophia Davidson et al.   Nature Communications

Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study

(2014) Andrew C Hayward et al.   Lancet Respiratory Medicine

Systems Scale Interactive Exploration Reveals Quantitative and Qualitative Differences in Response to Influenza and Pneumococcal Vaccines

(2013) Gerlinde Obermoser et al.   IMMUNITY

A(H1N1)pdm09 hemagglutinin D222G and D222N variants are frequently harbored by patients requiring extracorporeal membrane oxygenation and advanced respiratory assistance for severe A(H1N1)pdm09 infection

(2013) Tina Ruggiero et al.   Influenza and Other Respiratory Viruses

Bacterial Complications of Respiratory Tract Viral Illness: A Comprehensive Evaluation

(2013) A. R. Falsey et al.   JOURNAL OF INFECTIOUS DISEASES

Pathogenesis of influenza-induced acute respiratory distress syndrome

(2013) Kirsty R Short et al.   LANCET INFECTIOUS DISEASES

Molecular signatures of antibody responses derived from a systems biology study of five human vaccines

(2013) Shuzhao Li et al.   NATURE IMMUNOLOGY

Protective and dysregulated T cell immunity in RSV infection

(2013) Peter J Openshaw et al.   Current Opinion in Virology

Can procalcitonin tests aid in identifying bacterial infections associated with influenza pneumonia? A systematic review and meta-analysis

(2012) Meng-Huan Wu et al.   Influenza and Other Respiratory Viruses

Plasticity and Virus Specificity of the Airway Epithelial Cell Immune Response during Respiratory Virus Infection

(2012) I. Ioannidis et al.   JOURNAL OF VIROLOGY

Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study

(2012) Fatimah S Dawood et al.   LANCET INFECTIOUS DISEASES

Into the Eye of the Cytokine Storm

(2012) J. R. Tisoncik et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

IFITM3 restricts the morbidity and mortality associated with influenza

(2012) Aaron R. Everitt et al.   NATURE

Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis

(2011) Teluguakula Narasaraju et al.   AMERICAN JOURNAL OF PATHOLOGY

Neutrophils sustain effective CD8+ T-cell responses in the respiratory tract following influenza infection

(2011) Michelle D Tate et al.   IMMUNOLOGY AND CELL BIOLOGY

Systems biology of vaccination for seasonal influenza in humans

(2011) Helder I Nakaya et al.   NATURE IMMUNOLOGY

A Genomic Approach to Human Autoimmune Diseases

(2010) Virginia Pascual et al.   Annual Review of Immunology

Introduction of Virulence Markers in PB2 of Pandemic Swine-Origin Influenza Virus Does Not Result in Enhanced Virulence or Transmission

(2010) S. Herfst et al.   JOURNAL OF VIROLOGY

Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Risk factors for hospitalisation and poor outcome with pandemic A/H1N1 influenza: United Kingdom first wave (May-September 2009)

(2010) J. S. Nguyen-Van-Tam et al.   THORAX

Gene Expression Signatures Diagnose Influenza and Other Symptomatic Respiratory Viral Infections in Humans

(2009) Aimee K. Zaas et al.   Cell Host & Microbe

Clinical Management of Pandemic 2009 Influenza A(H1N1) Infection

(2009) David S. Hui et al.   CHEST

Development of a real-time RT-PCR for the detection of Swine-lineage Influenza A (H1N1) virus infections

(2009) Michael J. Carr et al.   JOURNAL OF CLINICAL VIROLOGY

A Systemic Neutrophil Response Precedes Robust CD8+ T-Cell Activation during Natural Respiratory Syncytial Virus Infection in Infants

(2009) M. V. Lukens et al.   JOURNAL OF VIROLOGY

Innate immune responses to influenza A H5N1: friend or foe?

(2009) Joseph Sriyal Malik Peiris et al.   TRENDS IN IMMUNOLOGY

Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis

(2009) Rungnapa Pankla et al.   GENOME BIOLOGY

A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus

(2008) Damien Chaussabel et al.   IMMUNITY