Resistance of HIV-infected macrophages to CD8+ T lymphocyte–mediated killing drives activation of the immune system

HIV persistence in tissue macrophages of humanized myeloid-only mice during antiretroviral therapy

(2017) Jenna B Honeycutt et al.   NATURE MEDICINE

Brain Macrophages in Simian Immunodeficiency Virus-Infected, Antiretroviral-Suppressed Macaques: a Functional Latent Reservoir

(2017) Claudia R. Avalos et al.   mBio

Short Communication: HIV Controller T Cells Effectively Inhibit Viral Replication in Alveolar Macrophages

(2016) Victoria E. Walker-Sperling et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Macrophages and HIV-1: An Unhealthy Constellation

(2016) Quentin J. Sattentau et al.   Cell Host & Microbe

Macrophages sustain HIV replication in vivo independently of T cells

(2016) Jenna B. Honeycutt et al.   JOURNAL OF CLINICAL INVESTIGATION

Quantitation of Productively Infected Monocytes and Macrophages of Simian Immunodeficiency Virus-Infected Macaques

(2016) Claudia R. Avalos et al.   JOURNAL OF VIROLOGY

Macrophages in Progressive Human Immunodeficiency Virus/Simian Immunodeficiency Virus Infections

(2016) Sarah R. DiNapoli et al.   JOURNAL OF VIROLOGY

SIV Encephalitis Lesions Are Composed of CD163+ Macrophages Present in the Central Nervous System during Early SIV Infection and SIV-Positive Macrophages Recruited Terminally with AIDS

(2015) Brian T. Nowlin et al.   AMERICAN JOURNAL OF PATHOLOGY

Blocking interferon γ reduces expression of chemokines CXCL9, CXCL10 and CXCL11 and decreases macrophage infiltration in ex vivo cultured arteries from patients with giant cell arteritis

(2015) Marc Corbera-Bellalta et al.   ANNALS OF THE RHEUMATIC DISEASES

Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time

(2015) Misty R. Jenkins et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Nef Is Dispensable for Resistance of Simian Immunodeficiency Virus-Infected Macrophages to CD8+T Cell Killing

(2015) Jennifer N. Rainho et al.   JOURNAL OF VIROLOGY

Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice

(2015) José Belizário et al.   MEDIATORS OF INFLAMMATION

Comparative Analysis of the Capacity of Elite Suppressor CD4+ and CD8+ T Cells To Inhibit HIV-1 Replication in Monocyte-Derived Macrophages

(2014) V. E. K. Walker-Sperling et al.   JOURNAL OF VIROLOGY

HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes

(2014) F. Pereyra et al.   JOURNAL OF VIROLOGY

Granzyme M targets topoisomerase II alpha to trigger cell cycle arrest and caspase-dependent apoptosis

(2013) S A H de Poot et al.   CELL DEATH AND DIFFERENTIATION

High-Multiplicity HIV-1 Infection and Neutralizing Antibody Evasion Mediated by the Macrophage-T Cell Virological Synapse

(2013) C. J. A. Duncan et al.   JOURNAL OF VIROLOGY

Granzyme H induces cell death primarily via a Bcl-2-sensitive mitochondrial cell death pathway that does not require direct Bid activation

(2013) Catherine L. Ewen et al.   MOLECULAR IMMUNOLOGY

Increased coronary atherosclerosis and immune activation in HIV-1 elite controllers

(2012) Florencia Pereyra et al.   AIDS

HIV-1 Nef in Macrophage-Mediated Disease Pathogenesis

(2012) Susanna L. Lamers et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Tyrosine kinase pathways modulate tumor susceptibility to natural killer cells

(2012) Roberto Bellucci et al.   JOURNAL OF CLINICAL INVESTIGATION

The Majority of Freshly Sorted Simian Immunodeficiency Virus (SIV)-Specific CD8+T Cells Cannot Suppress Viral Replication in SIV-Infected Macrophages

(2012) Lara Vojnov et al.   JOURNAL OF VIROLOGY

Granzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737

(2012) V R Sutton et al.   Cell Death & Disease

Endosomal clathrin drives actin accumulation at the immunological synapse

(2011) C. Calabia-Linares et al.   JOURNAL OF CELL SCIENCE

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

T Cell Immunity in Acute HIV‐1 Infection

(2010) Hendrik Streeck et al.   JOURNAL OF INFECTIOUS DISEASES

Perforin Expression Directly Ex Vivo by HIV-Specific CD8+ T-Cells Is a Correlate of HIV Elite Control

(2010) Adam R. Hersperger et al.   PLoS Pathogens

Control of granzymes by serpins

(2009) D Kaiserman et al.   CELL DEATH AND DIFFERENTIATION

Neutralization of IFNγ defeats haemophagocytosis in LCMV-infected perforin- and Rab27a-deficient mice

(2009) Jana Pachlopnik Schmid et al.   EMBO Molecular Medicine

Defective Human Immunodeficiency Virus-Specific CD8+ T-Cell Polyfunctionality, Proliferation, and Cytotoxicity Are Not Restored by Antiretroviral Therapy

(2009) S. A. Migueles et al.   JOURNAL OF VIROLOGY

Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses

(2008) F. Groot et al.   BLOOD

Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control

(2008) Stephen A. Migueles et al.   IMMUNITY

Magnitude and Complexity of Rectal Mucosa HIV-1-Specific CD8+ T-Cell Responses during Chronic Infection Reflect Clinical Status

(2008) J. William Critchfield et al.   PLoS One