Article
Chemistry, Applied
Zhang-Zhen Bai, Jing Ni, Jun-Man Tang, Dao-Yang Sun, Zhen-Guo Yan, Jing Zhang, Li-Xin Niu, Yan-Long Zhang
Summary: This study identified and quantified 29 bioactive components in tree peony fruit, with specific chemical markers identified between seeds and pods. Significant correlations between antioxidant activities and total phenolic content and total flavonoid content were observed. The study suggests that tree peony fruit could be a potential source of bioactive compounds with various functional properties.
Article
Agriculture, Multidisciplinary
Wenjia He, Oskar Laaksonen, Ye Tian, Tuuli Haikonen, Baoru Yang
Summary: The phenolic profiles and other major metabolites in European pear juices were investigated using UHPLC-DAD-ESI-QTOF-MS and GC-FID. A total of 39 phenolic compounds were detected, and the content variations were mainly dependent on the cultivar. The genetic background and breeding selections also played a role in the chemical compositions. The results provide important information for industry and pear breeding.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Food Science & Technology
Zhang-Zhen Bai, Jun-Man Tang, Jing Ni, Tian-Tian Zheng, Yang Zhou, Dao-Yang Sun, Guang-Ning Li, Pu Liu, Li-Xin Niu, Yan-Long Zhang
Summary: This study comprehensively investigated the phytochemical constituents and biological activities of different parts of tree peony fruits, revealing that the extracts from fruit pod and seed coat showed stronger antioxidant, antibacterial, and anti-neuroinflammatory activities compared to the seed kernel. The research highlights the potential utilization of tree peony fruit as a natural source of bioactive components in food and pharmaceutical industries.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Biochemistry & Molecular Biology
Mindaugas Liaudanskas, Irena Noreikiene, Kristina Zymone, Rugile Juodyte, Vaidotas Zvikas, Valdimaras Janulis
Summary: In this study, qualitative and quantitative analysis of phenolic compounds in the fruit of Rosa L. cultivars grown in Lithuania revealed variations in the composition and antioxidant activity among different cultivars. The total content of phenolic compounds and the antioxidant activity showed strong correlation, indicating the potential health benefits of consuming these fruits.
Article
Food Science & Technology
Yunting Zhang, Chengwu Song, Hongzhi Du, Yulin Chen, Xiao Huang, Ling Gong, Pengtao You, Juan Deng, Yimei Liu, Haidong Feng, Zezhi Zhang, Kun Yu, Yunzhong Chen
Summary: Polygonum cuspidatum shoots, consumed as a traditional vegetable in the Shennongjia region of China, have been found to have biological effects such as antibacterial, anti-aging, and antioxidant. This study evaluated the safety, chemical composition, and antioxidant activity of SPC in vivo and in vitro. The results showed that SPC is a safe, multifunctional food with antioxidant and hepatoprotective activities.
FOOD QUALITY AND SAFETY
(2022)
Article
Food Science & Technology
Yunting Zhang, Chengwu Song, Hongzhi Du, Yulin Chen, Xiao Huang, Ling Gong, Pengtao You, Juan Deng, Yimei Liu, Haidong Feng, Zezhi Zhang, Kun Yu, Yunzhong Chen
Summary: The shoots of Polygonum cuspidatum (SPC) have been consumed as a traditional vegetable in China for centuries. This study evaluated the safety, chemical composition, and antioxidant activity of SPC, and found that it is a safe and multifunctional food with antioxidant and hepatoprotective activities. The chemical composition of SPC includes phenolic, flavonoid, stilbene, and anthraquinone compounds. Consumption of SPC as a functional food provides a novel strategy for the efficient utilization of invasive plants.
FOOD QUALITY AND SAFETY
(2022)
Article
Plant Sciences
Soraia I. Pedro, Tiago A. Fernandes, Angelo Luis, Alexandra M. M. Antunes, Jose C. Goncalves, Jorge Gominho, Eugenia Gallardo, Ofelia Anjos
Summary: This study evaluated the potential industrial applications of various Acacia species by examining their chemical composition, antioxidant, and antimicrobial properties. Among the studied species, A. pycnantha exhibited a higher concentration of total phenolic compounds and displayed notable antibacterial activity. Vibrational spectroscopy was a reliable method for distinguishing between species.
Article
Biochemistry & Molecular Biology
Habiba Rechek, Ammar Haouat, Kaouther Hamaidia, Hamza Allal, Tarek Boudiar, Diana C. G. A. Pinto, Susana M. Cardoso, Chawki Bensouici, Noureddine Soltani, Artur M. S. Silva
Summary: The study analyzed the phenolic profile, chemical composition, and antioxidant activity of the North African endemic plant Warionia saharae. Results showed that the extract has a high capacity to capture radicals, strong alpha-glucosidase inhibition, and anti-inflammatory activity.
Article
Biochemistry & Molecular Biology
Yeong Ran Im, Inhwan Kim, Jihyun Lee
Summary: The outer layer of purple sweet potato is a potential source of phenolics, especially anthocyanins, and exhibits high antioxidant activity. Cultivars 'Sinjami' and 'Jami' have higher levels of anthocyanins and other phenolic compounds in their outer layers, contributing to greater antioxidant activity.
Article
Biochemistry & Molecular Biology
Vanessa B. Paula, Leticia M. Estevinho, Susana M. Cardoso, Luis G. Dias
Summary: Propolis, a natural product produced by bees, contains a complex mixture of compounds that contribute to its biological activities, such as antioxidant capacity. This study analyzed the pollen profile, phenolic compound content, antioxidant properties, and phenolic compound profile of four propolis samples from Portugal. Different techniques were used to determine total phenolic content and antioxidant capacity, and the presence of specific compounds in propolis samples significantly impacted their antioxidant capacity and quantification of total phenolic content. The major compounds identified in the propolis samples were chrysin, caffeic acid isoprenyl ester, pinocembrin, galangin, pinobanksin-3-O-acetate, and caffeic acid phenyl ester. The study highlights the importance of method selection for determining phenolic content and antioxidant activity in propolis samples and the contribution of specific compounds to their quantification.
Article
Plant Sciences
Laima Cesoniene, Paulina Streimikyte, Mindaugas Liaudanskas, Vaidotas Zvikas, Pranas Viskelis, Jonas Viskelis, Remigijus Daubaras
Summary: The research found that berries and leaves of Actinidia kolomikta contain various phenolic compounds and their antioxidant activity is cultivar-dependent. The highest total content of phenolic compounds was found in the leaves of the cultivar 'Aromatnaja' and in the berries of the cultivar 'VIR-2'.
Article
Plant Sciences
Patrick Yamen Mbopi, Hermann Didy S. Fozeng, Yves Martial M. Nguekeu, Gabin Thierry M. Bitchagno, Claude Berenger N. Ngantchouko, Maurice Ducret Awouafack, Till Opatz, Sylvere Augustin Ngouela, Hiroyuki Morita, Mathieu Tene
Summary: This study investigated the phytochemical constituents of the ethanol extract of Dicliptera verticillata and evaluated its antioxidant and antibacterial activities. Results showed moderate antioxidant activity, weak total phenolic content, and bactericidal effect against both Gram-positive and Gram-negative bacteria.
SOUTH AFRICAN JOURNAL OF BOTANY
(2021)
Article
Biochemistry & Molecular Biology
Rachid Chawech, Sabrina Pesnel, Maroua Ben Haddada, Anne Gauvin-Bialecki, Anne-Laure Morel
Summary: This study investigated the phytochemical components and antioxidant properties of an aqueous extract from the medicinal plant Hubertia ambavilla, endemic to Reunion Island. The study identified 37 compounds using high-performance liquid chromatography (UHPLC) and determined the quantities of secondary metabolites in the extract. The results showed that the aqueous extract had effective antioxidant properties, indicating its potential as a natural alternative source of antioxidants for the food and health industries.
CHEMISTRY & BIODIVERSITY
(2022)
Article
Agronomy
Eman A. Mohammed, Ismat G. Abdalla, Mohammed A. Alfawaz, Mohammed A. Mohammed, Salah A. Al Maiman, Magdi A. Osman, Abu ElGasim A. Yagoub, Amro B. Hassan
Summary: This study investigated the total phenolics, total flavonoids, and antioxidant activity of the aerial parts of onion, white radish, red radish, carrot, and beet. The results showed that these vegetables have high antioxidant properties, with root vegetables exhibiting particularly strong antioxidant capacity.
Article
Food Science & Technology
Mehdi Akbari, Seyed Hadi Razavi, Faramarz Khodaiyan, Jesus Blesa, Maria J. Esteve
Summary: This study evaluated the potential of solid-state fermentation with Lactobacillus reuteri and Lactobacillus plantarum for improving phenolic compounds and antioxidant activity in corn bran. The results showed that fermentation significantly increased the total phenolic content and antioxidant activity of the fermented samples. It also increased the concentration of free phenolic acids. Therefore, solid-state fermentation is an effective method for enhancing phenolic compounds and antioxidant activity.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Virology
Chong Yu, Zhiguo Zhang, Yujiao Guo, Jing Shi, Guangchang Pei, Ying Yao, Wenhui Liao, Rui Zeng
Summary: This retrospective study of 128 hospitalized patients with COVID-19 pneumonia, 64 of whom were coinfected with influenza A/B, found that patients with coinfection had a longer duration of viral shedding and lopinavir/ritonavir treatment was associated with faster resolution of pneumonia. Lopinavir/ritonavir eliminated the difference in lung involvement between influenza coinfection and noninfection groups in COVID-19 patients, suggesting its potential in pneumonia resolution.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Engineering, Environmental
Jin-Shuai Lan, Li Liu, Rui-Feng Zeng, Yan-Hong Qin, Jian-Wei Hou, Sai-Sai Xie, Shuai Yue, Jun Yang, Rodney J. Y. Ho, Yue Ding, Tong Zhang
Summary: Combining chemotherapy and photodynamic therapy with a novel carrier-free nanodrug has shown promising results in enhancing treatment efficacy, indicating that depleting GSH through chemotherapy can improve the effectiveness of PDT.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Engineering, Environmental
Jin-Shuai Lan, Rui-Feng Zeng, Yu Wang, Lu Zhen, Yun Liu, Rodney J. Y. Ho, Yue Ding, Tong Zhang
Summary: A fluorescent probe based on intramolecular charge transfer was developed for the detection of SO2 derivatives, allowing for accurate quantification, real-time monitoring, and bioimaging of SO32-/HSO3-.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Review
Cell & Tissue Engineering
Ruijie Zeng, Jinghua Wang, Zewei Zhuo, Yujun Luo, Weihong Sha, Hao Chen
Summary: Necrotizing enterocolitis (NEC) is a devastating disease predominantly affecting neonates, with stem cells and exosomes showing promising effects for treatment. Further research, bioengineering improvements, and rigorous clinical trials are needed for the development of novel therapeutic strategies.
STEM CELL RESEARCH & THERAPY
(2021)
Article
Oncology
Huai-yu Wang, Suyuan Peng, Zhanghui Ye, Pengfei Li, Qing Li, Xuanyu Shi, Rui Zeng, Ying Yao, Fan He, Junhua Li, Liu Liu, Shuwang Ge, Xianjun Ke, Zhibin Zhou, Gang Xu, Ming-hui Zhao, Haibo Wang, Luxia Zhang, Erdan Dong
Summary: The study found that the use of RAS-I and ARB in COVID-19 patients can reduce the risk of all-cause mortality, especially for patients with hypertension.
FRONTIERS OF MEDICINE
(2022)
Article
Polymer Science
Xinyi Luo, Kunlun Zhang, Ruiming Zeng, Ying Chen, Li Zhang, Jianbo Tan
Summary: A novel difunctional RAFT agent with an asymmetric structure was synthesized and used to prepare segmented macro-RAFT agents, leading to the formation of segmented copolymers with different blocks. Introduction of a certain number of trithiocarbonate groups on the surface of block copolymer nano-objects was achieved, providing a platform for further chain extension and functionalization. This study not only provides important mechanistic insights into RAFT polymerization mediated by multifunctional RAFT agents but also enables the preparation of functional block copolymer nano-objects.
Article
Chemistry, Medicinal
Guanlan Chen, Rui Zeng, Xin Wang, Hongying Cai, Jiajia Chen, Yingxiong Zhong, Saiyi Zhong, Xuejing Jia
Summary: Clam heparinoid G2 and its depolymerized derivatives DG1 and DG2 have shown excellent fibrinolytic and anticoagulant activity. Results indicate that G2 has a high anticoagulant effect, while DG2 has a greater thrombolytic activity. Furthermore, oral administration of DG1 reduces thrombus formation, increases tissue-type plasminogen activator levels, and improves changes in intestinal bacteria. These findings suggest that DG1 could be an oral agent with antithrombotic properties.
Article
Medicine, General & Internal
R. Zeng, H. Wu, X. Qiu, Z. Zhuo, W. Sha, H. Chen
Summary: This study developed an effective prognostic signature for predicting colorectal cancer (CRC) by evaluating the signal transducer and activator of transcription (STAT) signaling. The signature was significantly associated with CRC survival and correlated with the tumor immune microenvironment. The hub gene Caveolin-1 (CAV1) within the signature was found to inhibit cell proliferation, induce apoptosis and senescence, and suppress tumor angiogenesis in CRC. This research highlights the importance of the STAT regulator CAV1 and suggests that modulating STAT and its regulators could be a promising strategy for CRC in clinical practice.
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Barbara Santos, Rui Zeng, Sasa F. Jorge, Jose Ribamar Ferreira-Junior, Antoni Barrientos, Mario H. Barros
Summary: Mitoribosomes in Saccharomyces cerevisiae consist of a 54S large subunit and a 37S small subunit, containing a total of 73 mitoribosome proteins and two ribosomal RNAs. These proteins have adapted by acquiring new proteins, extensions, and RNA segments, to synthesize highly hydrophobic membrane proteins. The study investigates the functional relevance of mitochondria-specific protein extensions in the mtLSU, revealing their importance in mitochondrial protein synthesis capacities and rRNAs interactions.
Review
Multidisciplinary Sciences
Ruijie Zeng, Zewei Zhuo, Yujun Luo, Weihong Sha, Hao Chen
Summary: Rho GTPases play crucial roles in the pathogenesis of various rheumatic diseases, promoting disease progression through activation of downstream pathways. Therapeutic strategies using Rho GTPase inhibitors have shown promising effects in the treatment of rheumatic diseases. Future studies should focus on further exploring the role of Rho GTPases in rheumatic diseases based on current understandings.
Article
Oncology
Yue Zheng, Kehang Guo, Ruijie Zeng, Zhendao Chen, Wanwei Liu, Xiaoguang Zhang, Weimin Liang, Jianhua Liu, Hao Chen, Weihong Sha
Summary: This study found that modified endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are safe and effective endoscopic approaches for the resection of rectal neuroendocrine tumors (NETs) with a diameter less than or equal to 15 mm. Preoperative evaluation of risk factors, including tumor invasion depth and diameter, is crucial for successful endoscopic resection.
JOURNAL OF GASTROINTESTINAL ONCOLOGY
(2021)
Article
Environmental Sciences
Tianfang Xu, Qianqiu Longyang, Conor Tyson, Ruijie Zeng, Bethany T. Neilson
Summary: This study presents a hybrid modeling approach that combines a physically based snow model with a deep learning karst model to predict streamflow in mountainous karst watersheds. The approach is tested on a watershed in northern Utah and shows high accuracy in simulating streamflow. The deep learning model captures the spatiotemporal recharge and discharge patterns and provides valuable insights into hydrologic responses influenced by complex surface and subsurface properties.
WATER RESOURCES RESEARCH
(2022)
Review
Medicine, General & Internal
Chujin Cao, Han Zhu, Ying Yao, Rui Zeng
Summary: Gut dysbiosis is a major mechanism in the development of kidney diseases, and improving the gut microbiota can potentially slow down the progression of kidney diseases.
FRONTIERS IN MEDICINE
(2022)
Proceedings Paper
Computer Science, Interdisciplinary Applications
Zixin Peng, Genglin Zhu, Mu Li, Ruifeng Zeng, Sibo Cheng, Kaisheng Wang
Summary: This paper investigates how to balance the safety and cost-effectiveness of UAVs in fighting forest fires. Through a case study, the particle swarm algorithm, topology spanning tree algorithm, and ant colony algorithm are used to optimize the patrol paths and minimize the cost of the drones.
2ND INTERNATIONAL CONFERENCE ON APPLIED MATHEMATICS, MODELLING, AND INTELLIGENT COMPUTING (CAMMIC 2022)
(2022)
Article
Oncology
Zheng Li, Haijie Xu, Jiaming Yu, Cantong Liu, Chunwen Zheng, Ruijie Zeng, Liyan Xu, Enmin Li, Yuhui Peng, Yiwei Xu
Summary: IL-8 levels in both mRNA expression and serum were significantly higher in EJA patients compared to normal controls, indicating a potential diagnostic value for early-stage EJA. Significant correlations were also found between IL-8 levels and clinical parameters such as patient gender, depth of invasion, lymph node metastasis, and TNM stage.