Review
Nutrition & Dietetics
Mihnea-Alexandru Gaman, Elena-Codruta Dobrica, Matei-Alexandru Cozma, Ninel-Iacobus Antonie, Ana Maria Alexandra Stanescu, Amelia Maria Gaman, Camelia Cristina Diaconu
Summary: This review explores the associations between magnesium and lipid profiles, showing a correlation between magnesium concentrations in the body and serum lipids in dyslipidemia and related disorders. Further research is needed to clarify whether higher magnesium intake through diet or supplements can affect lipid profiles.
Article
Biochemistry & Molecular Biology
Jingang Xu, Guofeng Xu, Junkang Fang
Summary: This study examined the relationship between serum copper and lipid levels in a sample of 3425 participants aged 20 and above. The results showed a positive association between serum copper concentrations and total cholesterol and LDL cholesterol levels among women. Additionally, higher serum copper levels were associated with increased risk of high total cholesterol in men. No significant association was found between serum copper and triglycerides levels. Further research with prospective data is needed to confirm the impact of copper on stroke health through effects on lipid levels.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Taiyue Jin, Eun Young Park, Byungmi Kim, Jin-Kyoung Oh
Summary: This study evaluated the association between serum folate concentrations and the prevalence of dyslipidemia and found a possible non-linear relationship. The findings suggest the need for more accurate recommendations regarding folate intake and supplementation.
EPIDEMIOLOGY AND HEALTH
(2022)
Editorial Material
Pharmacology & Pharmacy
Marko Nemet, Milica Vasilic, Ana Tomas
Summary: Carob pulp has been recognized as an effective natural product for the treatment of dyslipidemia due to its beneficial effects on lipid metabolism. Its main components, polyphenols and insoluble fiber, have been found to lower lipid levels and potentially affect the gastrointestinal tract, liver, and adipose tissue. Additionally, carob products exhibit antioxidative, anti-inflammatory, and vascular-protective activity.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Chao-Ying Miao, Xiao-Fei Ye, Wei Zhang, Chang-Sheng Sheng, Qi-Fang Huang, Ji-Guang Wang
Summary: This study investigated the relationship between serum triglycerides and all-cause, cardiovascular, and non-cardiovascular mortality in an elderly Chinese population. The results showed a high prevalence of hypertriglyceridemia, especially in those with borderline levels and in obese and overweight individuals. There was a slight but non-significant increase in the risk of cardiovascular mortality associated with serum triglycerides compared to the middle level.
JOURNAL OF GERIATRIC CARDIOLOGY
(2022)
Article
Endocrinology & Metabolism
Amanda J. Berberich, Robert A. Hegele
Summary: We have been using DNA sequencing in our lipid clinic for more than 20 years. Dyslipidemia is usually determined biochemically. For moderate deviations in the lipid profile, the etiology is often a combination of a polygenic susceptibility component and secondary non-genetic factors. Severe dyslipidemia is more likely to have a monogenic etiology, although a specific single-gene cause is often not found. A severe phenotype can also result from a strong polygenic predisposition aggravated by secondary factors. An early age of onset, a family history of dyslipidemia or atherosclerotic cardiovascular disease may suggest a monogenic etiology. Clinical examination focuses on detecting manifestations of monogenic syndromic conditions for severe dyslipidemia. Secondary causes must be ruled out for all patients with dyslipidemia. Here we describe an experience-based practical approach to genetic testing of patients with severe deviations in low-density lipoprotein, triglycerides, high-density lipoprotein, as well as combined hyperlipidemia and dysbetalipoproteinemia.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Genetics & Heredity
Hongqun Yang, Lanlan Chen, Kaiyu Liu, Chengnan Li, Haitao Li, Kezhen Xiong, Zehan Li, Chuang Lu, Wei Chen, Yahui Liu
Summary: The study found a minor protective effect of LDL cholesterol on cholecystitis, while total cholesterol, triglycerides, and HDL cholesterol showed no causal effect. The protective effect of serum lipids on cholecystitis, though possible, remain less certain.
BMC MEDICAL GENOMICS
(2021)
Article
Pharmacology & Pharmacy
Maisa Siddiq Abduh, Sultan A. M. Saghir, Amir M. Al Hroob, Albandari Bin-Ammar, Ayat H. Al-Tarawni, Vikneswaran Murugaiyah, Ayman M. Mahmoud
Summary: This study assessed the anti-hyperlipidemic and antioxidant activities of different fractions of the methanolic extract of the star fruit's leaves. The ethyl acetate fraction showed the most effective anti-hyperlipidemic and antioxidant effects. The findings suggest that the leaves of the star fruit can be a safe alternative for individuals with compromised kidney function who are unable to consume the fruit.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Urology & Nephrology
Gustavo Andrade, Ivan Iori, Mariana K. Hsieh, Giovanna Milani, Pedro C. E. Zandona, Thiago A. Teixeira, Joel R. Drevet, Elaine Maria Costa, Jorge Hallak
Summary: This study aimed to determine the relationship between serum lipid profile and testicular function. A retrospective study was conducted on 278 infertile men, and data on seminal analysis, lipid profile, and total serum testosterone were collected. The results showed that seminal creatine kinase activity was negatively related to HDL and triglycerides, while total testosterone and seminal volume were both negatively related to triglycerides. Therefore, a comprehensive assessment, including blood lipid profile, hormonal status, and routine seminal examinations, is recommended for infertile men.
INTERNATIONAL UROLOGY AND NEPHROLOGY
(2023)
Article
Geriatrics & Gerontology
Zoe White, Marine Theret, Nadia Milad, Lin Wei Tung, William Wei-Han Chen, Martin G. Sirois, Fabio Rossi, Pascal Bernatchez
Summary: Cholesterol exacerbates muscular dystrophy in rodent models, but specific inhibition of cholesterol absorption with ezetimibe can safely attenuate human MD severity and delay death.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Review
Biochemistry & Molecular Biology
Julia Nowowiejska, Anna Baran, Iwona Flisiak
Summary: Psoriasis is a common skin disease affecting about 1%-3% of the general population, often accompanied by cardiometabolic disorders. Research indicates that lipid expression and metabolism disorders are more common in psoriatic patients, playing a significant role in the pathogenesis of psoriasis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Endocrinology & Metabolism
Arthur Eumann Mesas, Miriam Garrido-Miguel, Ruben Fernandez-Rodriguez, Sofia Fernandez Franco, Cristina Lugones-Sanchez, Luis Garcia-Ortiz, Vicente Martinez-Vizcaino
Summary: This study examined the relationship between egg consumption and blood lipid parameters and found that higher egg consumption was not associated with total cholesterol, HDL cholesterol, and triglyceride levels, but was associated with lower LDL cholesterol levels and LDL/HDL ratio. In individuals with chronic metabolic disorders, higher egg consumption was not associated with lipid abnormalities, while in individuals without these conditions, those who consumed more eggs had better lipid profiles.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Hematology
Minghao Kou, Ning Ding, Shoshana H. Ballew, Maya J. Salameh, Seth S. Martin, Elizabeth Selvin, Gerardo Heiss, Christie M. Ballantyne, Kunihiro Matsushita, Ron C. Hoogeveen
Summary: Triglyceride-related and HDL-related lipids were independently associated with incident PAD, indicating implications for preventive strategies. Principal component analysis identified three components related to PAD risk.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2021)
Article
Medicine, General & Internal
Meleeka Akbarpour, Divya Devineni, Yufan Gong, Nathan D. Wong
Summary: This study examined lipid levels and treatment status in patients with diabetes mellitus (DM), finding a lack of guideline-recommended use of high-intensity statins and inadequately controlled LDL-C among high-risk DM patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
Guizhi Deng, Yunjie Li, Wenke Cheng
Summary: The study aimed to investigate the relationship between lipid profile and prevalence of hypertension in Chinese adult women. The results showed that TC, LDL-c, and non-HDL-c were positively associated with hypertension prevalence, while HDL-c was negatively associated with hypertension prevalence but became nonsignificant after full adjustment for variables.
FRONTIERS IN ENDOCRINOLOGY
(2022)