Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer’s Disease
出版年份 2018 全文链接
标题
Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer’s Disease
作者
关键词
Memantine, Obesity, Diabetes, APPswe/PS1dE9, High-fat diet, Alzheimer’s disease
出版物
MOLECULAR NEUROBIOLOGY
Volume -, Issue -, Pages -
出版商
Springer Nature
发表日期
2018-02-05
DOI
10.1007/s12035-018-0868-4
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Pancreas-Brain Axis: Insight into Disrupted Mechanisms Associating Type 2 Diabetes and Alzheimer's Disease
- (2018) Gauri S. Desai et al. JOURNAL OF ALZHEIMERS DISEASE
- Memantine reduces the production of amyloid-β peptides through modulation of amyloid precursor protein trafficking
- (2017) Kaori Ito et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Glucose tolerance and insulin sensitivity are impaired in APP/PS1 transgenic mice prior to amyloid plaque pathogenesis and cognitive decline
- (2017) Lauren Macklin et al. EXPERIMENTAL GERONTOLOGY
- New potential strategies for Alzheimer's disease prevention: pegylated biodegradable dexibuprofen nanospheres administration to APPswe/PS1dE9
- (2017) Elena Sánchez-López et al. Nanomedicine-Nanotechnology Biology and Medicine
- A systemic view of Alzheimer disease — insights from amyloid-β metabolism beyond the brain
- (2017) Jun Wang et al. Nature Reviews Neurology
- Insulin potentiates the therapeutic effect of memantine against central STZ-induced spatial learning and memory deficit
- (2016) Abbas Bahramian et al. BEHAVIOURAL BRAIN RESEARCH
- NMDA Receptors as Potential Therapeutic Targets in Diabetic Nephropathy: Increased Renal NMDA Receptor Subunit Expression in Akita Mice and Reduced Nephropathy Following Sustained Treatment With Memantine or MK-801
- (2016) Hila Roshanravan et al. DIABETES
- IRS proteins and diabetic complications
- (2016) Deborah P. Lavin et al. DIABETOLOGIA
- Neuronal human BACE1 knockin induces systemic diabetes in mice
- (2016) Kaja Plucińska et al. DIABETOLOGIA
- Increased oxidative stress and apoptosis in the hypothalamus of diabetic male mice in the insulin receptor substrate-2 knockout model
- (2016) Eva Baquedano et al. Disease Models & Mechanisms
- Insulin Resistance and Neurodegeneration: Progress Towards the Development of New Therapeutics for Alzheimer’s Disease
- (2016) Suzanne M. de la Monte DRUGS
- The amyloid hypothesis of Alzheimer's disease at 25 years
- (2016) Dennis J Selkoe et al. EMBO Molecular Medicine
- Aβ Amyloid Pathology Affects the Hearts of Patients With Alzheimer’s Disease
- (2016) Luca Troncone et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Need for Better Diabetes Treatment: The Therapeutic Potential of NMDA Receptor Antagonists
- (2016) A. Welters et al. KLINISCHE PADIATRIE
- Gender differences of peripheral plasma and liver metabolic profiling in APP/PS1 transgenic AD mice
- (2016) Junfang Wu et al. NEUROSCIENCE
- Amantadine reduces glucagon and enhances insulin secretion throughout the oral glucose tolerance test: central plus peripheral nervous system mechanisms
- (2016) Fuad Lechin Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
- Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis
- (2015) Kirsten L. Viola et al. ACTA NEUROPATHOLOGICA
- A Key Role of Insulin Receptors in Memory: Figure 1
- (2015) Fernanda G. De Felice et al. DIABETES
- Effects of dextromethorphan as add-on to sitagliptin on blood glucose and serum insulin concentrations in individuals with type 2 diabetes mellitus: a randomized, placebo-controlled, double-blinded, multiple crossover, single-dose clinical trial
- (2015) J. Marquard et al. DIABETES OBESITY & METABOLISM
- Alzheimer-associated A oligomers impact the central nervous system to induce peripheral metabolic deregulation
- (2015) J. R. Clarke et al. EMBO Molecular Medicine
- Inhibitory Effect of Memantine on Streptozotocin-Induced Insulin Receptor Dysfunction, Neuroinflammation, Amyloidogenesis, and Neurotrophic Factor Decline in Astrocytes
- (2015) N. Rajasekar et al. MOLECULAR NEUROBIOLOGY
- Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment
- (2015) Jan Marquard et al. NATURE MEDICINE
- Beta cell glutamate receptor antagonists: novel oral antidiabetic drugs?
- (2015) Claes B Wollheim et al. NATURE MEDICINE
- Hippocampal insulin resistance and cognitive dysfunction
- (2015) Geert Jan Biessels et al. NATURE REVIEWS NEUROSCIENCE
- Aberrant insulin signaling in Alzheimer's disease: current knowledge
- (2015) Gaurav Bedse et al. Frontiers in Neuroscience
- Alzheimer's disease
- (2015) Colin L. Masters et al. Nature Reviews Disease Primers
- How does brain insulin resistance develop in Alzheimer's disease?
- (2014) Fernanda G. De Felice et al. Alzheimers & Dementia
- Is Alzheimer's disease a systemic disease?
- (2014) Jill K. Morris et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes to Alzheimer Disease
- (2014) F. G. De Felice et al. DIABETES
- IRS2 integrates insulin/IGF1 signalling with metabolism, neurodegeneration and longevity
- (2014) M. F. White DIABETES OBESITY & METABOLISM
- Clearance of Amyloid-Beta in Alzheimer’s Disease: Shifting the Action Site from Center to Periphery
- (2014) Yu-Hui Liu et al. MOLECULAR NEUROBIOLOGY
- Interaction study of acetylcholinestrase inhibitors on pharmacokinetics of memantine in rat plasma by HPLC-fluorescence method
- (2013) Mohamed G. Hassan et al. BIOMEDICAL CHROMATOGRAPHY
- Brain Insulin Resistance and Deficiency as Therapeutic Targets in Alzheimers Disease
- (2012) Suzanne M. de la Monte Current Alzheimer Research
- Amyloid- Induces Hepatic Insulin Resistance by Activating JAK2/STAT3/SOCS-1 Signaling Pathway
- (2012) Y. Zhang et al. DIABETES
- Amyloid- Induces Hepatic Insulin Resistance In Vivo via JAK2
- (2012) Y. Zhang et al. DIABETES
- Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
- (2012) Konrad Talbot et al. JOURNAL OF CLINICAL INVESTIGATION
- Insulin resistance and AD—extending the translational path
- (2012) Suzanne Craft Nature Reviews Neurology
- Can Alzheimer Disease Be a Form of Type 3 Diabetes?
- (2012) Giulia Accardi et al. REJUVENATION RESEARCH
- Brain Insulin Signaling and Alzheimer's Disease: Current Evidence and Future Directions
- (2011) Helgi B. Schiöth et al. MOLECULAR NEUROBIOLOGY
- Resolving controversies on the path to Alzheimer's therapeutics
- (2011) Dennis J Selkoe NATURE MEDICINE
- Brain insulin signaling: A key component of cognitive processes and a potential basis for cognitive impairment in type 2 diabetes
- (2011) Ewan C. McNay et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- IRS2 and PTP1B: Two opposite modulators of hepatic insulin signalling
- (2011) Ángela M. Valverde et al. ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
- Alzheimer's disease: clinical trials and drug development
- (2010) Francesca Mangialasche et al. LANCET NEUROLOGY
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Memantine lowers amyloid-β peptide levels in neuronal cultures and in APP/PS1 transgenic mice
- (2009) George M. Alley et al. JOURNAL OF NEUROSCIENCE RESEARCH
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