Wnt-signaling enhances neural crest migration of melanoma cells and induces an invasive phenotype

WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner

(2017) K Brown et al.   ONCOGENE

NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF

(2017) Mitchell E. Fane et al.   EBioMedicine

MITF and BRN2 contribute to metastatic growth after dissemination of melanoma

(2017) Jacinta L. Simmons et al.   Scientific Reports

ZEB1‐mediated melanoma cell plasticity enhances resistance to MAPK inhibitors

(2016) Geoffrey Richard et al.   EMBO Molecular Medicine

Improvement of overall survival in stage IV melanoma patients during 2011–2014: analysis of real-world data in 441 patients of the German Central Malignant Melanoma Registry (CMMR)

(2016) Andrea Forschner et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

A Nexus Consisting of Beta-Catenin and Stat3 Attenuates BRAF Inhibitor Efficacy and Mediates Acquired Resistance to Vemurafenib

(2016) Tobias Sinnberg et al.   EBioMedicine

Genomic Classification of Cutaneous Melanoma

(2015) Rehan Akbani et al.   CELL

Protein Depalmitoylation Is Induced by Wnt5a and Promotes Polarized Cell Behavior

(2015) Wei Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

(2015) Stefani Spranger et al.   NATURE

Microphthalmia-associated transcription factor in melanoma development and MAP-kinase pathway targeted therapy

(2015) Claudia Wellbrock et al.   Pigment Cell & Melanoma Research

LEF-1 Regulates Tyrosinase Gene Transcription In Vitro

(2015) Xueping Wang et al.   PLoS One

Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma

(2014) Tobias Bald et al.   NATURE

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

(2013) Omid Hamid et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Chick Embryo as an Experimental System for Melanoma Cell Invasion

(2013) Christian Busch et al.   PLoS One

A Wnt-er Migration: The Confusing Role of  -Catenin in Melanoma Metastasis

(2013) M. R. Webster et al.   Science Signaling

The Small GTPase ARF6 Stimulates  -Catenin Transcriptional Activity During WNT5A-Mediated Melanoma Invasion and Metastasis

(2013) A. H. Grossmann et al.   Science Signaling

Modeling Neural Crest Induction, Melanocyte Specification, and Disease-Related Pigmentation Defects in hESCs and Patient-Specific iPSCs

(2013) Yvonne Mica et al.   Cell Reports

MHC class I molecules act as tumor suppressor genes regulating the cell cycle gene expression, invasion and intrinsic tumorigenicity of melanoma cells

(2012) Cristina Garrido et al.   CARCINOGENESIS

FGF signaling transforms non-neural ectoderm into neural crest

(2012) Nathan Yardley et al.   DEVELOPMENTAL BIOLOGY

Extracellular Matrix Protein Anosmin Promotes Neural Crest Formation and Regulates FGF, BMP, and WNT Activities

(2012) Yukinori Endo et al.   DEVELOPMENTAL CELL

Human melanoma cells in the rhombencephalon of the chick embryo: a novel model for brain metastasis

(2012) Christian Busch et al.   EXPERIMENTAL DERMATOLOGY

Molecular basis for the tissue specificity of β-catenin oncogenesis

(2012) A Sharma et al.   ONCOGENE

β-Catenin Signaling Controls Metastasis in Braf-Activated Pten-Deficient Melanomas

(2011) William E. Damsky et al.   CANCER CELL

DHODH modulates transcriptional elongation in the neural crest and melanoma

(2011) Richard Mark White et al.   NATURE

In melanoma, beta-catenin is a suppressor of invasion

(2011) I Arozarena et al.   ONCOGENE

Melanoma cells in distinct growth phases retain specific invasive qualities during brain metastasis in vivo

(2011) Jelena Krochmann et al.   Pigment Cell & Melanoma Research

Silymarin Targets β-Catenin Signaling in Blocking Migration/Invasion of Human Melanoma Cells

(2011) Mudit Vaid et al.   PLoS One

β-Catenin Signaling Increases during Melanoma Progression and Promotes Tumor Cell Survival and Chemoresistance

(2011) Tobias Sinnberg et al.   PLoS One

Suppression of Casein Kinase 1  in Melanoma Cells Induces a Switch in  -Catenin Signaling to Promote Metastasis

(2010) T. Sinnberg et al.   CANCER RESEARCH

Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032

(2010) Jonas N Søndergaard et al.   Journal of Translational Medicine

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

(2010) Poulikos I. Poulikakos et al.   NATURE

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Anti-Inflammatory Drug Leflunomide Is an Agonist of the Aryl Hydrocarbon Receptor

(2010) Edmond F. O'Donnell et al.   PLoS One

A Re-evaluation of the “Oncogenic” Nature of Wnt/β-catenin Signaling in Melanoma and Other Cancers

(2010) Olivia M. Lucero et al.   Current Oncology Reports

Differential requirements of BMP and Wnt signalling during gastrulation and neurulation define two steps in neural crest induction

(2009) B. Steventon et al.   DEVELOPMENT

Silencing cAMP-response Element-binding Protein (CREB) IdentifiesCYR61as a Tumor Suppressor Gene in Melanoma

(2009) Andrey S. Dobroff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands

(2009) K. Kawajiri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activated Wnt/ss-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model

(2009) A. J. Chien et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lgl2 Executes Its Function as a Tumor Suppressor by Regulating ErbB Signaling in the Zebrafish Epidermis

(2009) Sven Reischauer et al.   PLoS Genetics

Crosstalk between AHR and Wnt signaling through R-Spondin1 impairs tissue regeneration in zebrafish

(2008) Lijoy K. Mathew et al.   FASEB JOURNAL

Noggin blocks invasive growth of murine B16-F1 melanoma cells in the optic cup of the chick embryo

(2007) Christian Busch et al.   INTERNATIONAL JOURNAL OF CANCER