The Small GTPase ARF6 Stimulates  -Catenin Transcriptional Activity During WNT5A-Mediated Melanoma Invasion and Metastasis

Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development

(2012) Renée van Amerongen et al.   DEVELOPMENTAL BIOLOGY

Interleukin receptor activates a MYD88–ARNO–ARF6 cascade to disrupt vascular stability

(2012) Weiquan Zhu et al.   NATURE

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

(2012) Andrew V. Biankin et al.   NATURE

Wnt5a: its signalling, functions and implication in diseases

(2011) A. Kikuchi et al.   Acta Physiologica

FoxM1 Promotes β-Catenin Nuclear Localization and Controls Wnt Target-Gene Expression and Glioma Tumorigenesis

(2011) Nu Zhang et al.   CANCER CELL

β-Catenin Signaling Controls Metastasis in Braf-Activated Pten-Deficient Melanomas

(2011) William E. Damsky et al.   CANCER CELL

Robo4-dependent Slit signaling stabilizes the vasculature during pathologic angiogenesis and cytokine storm

(2011) Nyall R London et al.   CURRENT OPINION IN HEMATOLOGY

SLIT/ROBO1 Signaling Suppresses Mammary Branching Morphogenesis by Limiting Basal Cell Number

(2011) Hector Macias et al.   DEVELOPMENTAL CELL

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

In melanoma, beta-catenin is a suppressor of invasion

(2011) I Arozarena et al.   ONCOGENE

Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching

(2011) Ossia M. Eichhoff et al.   Pigment Cell & Melanoma Research

β-Catenin Signaling Increases during Melanoma Progression and Promotes Tumor Cell Survival and Chemoresistance

(2011) Tobias Sinnberg et al.   PLoS One

Microvesicles: mediators of extracellular communication during cancer progression

(2010) V. Muralidharan-Chari et al.   JOURNAL OF CELL SCIENCE

An Accurate, Clinically Feasible Multi-Gene Expression Assay for Predicting Metastasis in Uveal Melanoma

(2010) Michael D. Onken et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lentiviral Vectors to Probe and Manipulate the Wnt Signaling Pathway

(2010) Christophe Fuerer et al.   PLoS One

Targeting Robo4-Dependent Slit Signaling to Survive the Cytokine Storm in Sepsis and Influenza

(2010) N. R. London et al.   Science Translational Medicine

ARF6-mediated endocytic recycling impacts cell movement, cell division and lipid homeostasis

(2010) Jill Kuglin Schweitzer et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

ADP-Ribosylation Factor 6 Regulates Tumorigenic and Invasive Properties In vivo

(2009) V. Muralidharan-Chari et al.   CANCER RESEARCH

ADP-Ribosylation Factor 6 Regulates Glioma Cell Invasion through the IQ-Domain GTPase-Activating Protein 1-Rac1-Mediated Pathway

(2009) B. Hu et al.   CANCER RESEARCH

Wnt11/5a Complex Formation Caused by Tyrosine Sulfation Increases Canonical Signaling Activity

(2009) Sang-Wook Cha et al.   CURRENT BIOLOGY

ARF6-Regulated Shedding of Tumor Cell-Derived Plasma Membrane Microvesicles

(2009) Vandhana Muralidharan-Chari et al.   CURRENT BIOLOGY

Towards an integrated view of Wnt signaling in development

(2009) R. van Amerongen et al.   DEVELOPMENT

Slit2–Robo4 signalling promotes vascular stability by blocking Arf6 activity

(2009) Christopher A. Jones et al.   NATURE CELL BIOLOGY

The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

(2009) M P O’Connell et al.   ONCOGENE

Activated Wnt/ss-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model

(2009) A. J. Chien et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interplay of Cadherin-Mediated Cell Adhesion and Canonical Wnt Signaling

(2009) J. Heuberger et al.   Cold Spring Harbor Perspectives in Biology

Targeting N-Cadherin Enhances Antitumor Activity of Cytotoxic Therapies in Melanoma Treatment

(2008) C. K. Augustine et al.   CANCER RESEARCH

WNT5A Expression Increases during Melanoma Progression and Correlates with Outcome

(2008) P. D. Da Forno et al.   CLINICAL CANCER RESEARCH

Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation

(2008) S.-W. Cha et al.   DEVELOPMENT

Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability

(2008) Christopher A Jones et al.   NATURE MEDICINE

Wnt5a Control of Cell Polarity and Directional Movement by Polarized Redistribution of Adhesion Receptors

(2008) E. S. Witze et al.   SCIENCE