Inhibition of hedgehog signaling ameliorates hepatic inflammation in mice with nonalcoholic fatty liver disease

Osteopontin induces ductular reaction contributing to liver fibrosis

(2014) Xiaodong Wang et al.   GUT

Osteopontin neutralisation abrogates the liver progenitor cell response and fibrogenesis in mice

(2014) J D Coombes et al.   GUT

Protein and mRNA expression of Shh, Smo and Gli1 and inhibition by cyclopamine in hepatocytes of rats with chronic fluorosis

(2014) Lina Zhao et al.   TOXICOLOGY LETTERS

Hedgehog pathway and pediatric nonalcoholic fatty liver disease

(2013) Marzena Swiderska-Syn et al.   HEPATOLOGY

Osteopontin: Versatile modulator of liver diseases

(2013) Sumiko Nagoshi   HEPATOLOGY RESEARCH

Non-canonical Hedgehog signaling contributes to chemotaxis in cholangiocarcinoma

(2013) Nataliya Razumilava et al.   JOURNAL OF HEPATOLOGY

Osteopontin delays resolution of liver fibrosis

(2013) Tung-Ming Leung et al.   LABORATORY INVESTIGATION

From NAFLD to NASH to cirrhosis—new insights into disease mechanisms

(2013) Alexander Wree et al.   Nature Reviews Gastroenterology & Hepatology

NAFLD, NASH and liver cancer

(2013) Gregory A. Michelotti et al.   Nature Reviews Gastroenterology & Hepatology

The mechanisms of Hedgehog signalling and its roles in development and disease

(2013) James Briscoe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Vismodegib Suppresses TRAIL-mediated Liver Injury in a Mouse Model of Nonalcoholic Steatohepatitis

(2013) Petra Hirsova et al.   PLoS One

Interactions among bone, liver, and adipose tissue predisposing to diabesity and fatty liver

(2013) Giovanni Musso et al.   TRENDS IN MOLECULAR MEDICINE

NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease

(2012) Wing-Kin Syn et al.   GUT

The Osteopontin Level in Liver, Adipose Tissue and Serum Is Correlated with Fibrosis in Patients with Alcoholic Liver Disease

(2012) Stéphanie Patouraux et al.   PLoS One

Hedgehog pathway activation parallels histologic severity of injury and fibrosis in human nonalcoholic fatty liver disease

(2011) Cynthia D. Guy et al.   HEPATOLOGY

Obesity, inflammation, and liver cancer

(2011) Beicheng Sun et al.   JOURNAL OF HEPATOLOGY

Increased production of sonic hedgehog by ballooned hepatocytes

(2011) Fatima Rangwala et al.   JOURNAL OF PATHOLOGY

Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

(2011) N. Kumashiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elevated Hedgehog/Gli signaling causes  -cell dedifferentiation in mice

(2011) L. Landsman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signals from dying hepatocytes trigger growth of liver progenitors

(2010) Y. Jung et al.   GUT

Cytosolic phospholipase A2α and peroxisome proliferator-activated receptor γ signaling pathway counteracts transforming growth factor β-mediated inhibition of primary and transformed hepatocyte growth

(2010) Chang Han et al.   HEPATOLOGY

Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis

(2010) Wing-Kin Syn et al.   HEPATOLOGY

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Osteopontin: A missing link between hedgehog signaling and fibrosis in nonalcoholic steatohepatitis

(2010) Mariana Verdelho Machado et al.   HEPATOLOGY

Hedgehog signaling in the liver

(2010) Alessia Omenetti et al.   JOURNAL OF HEPATOLOGY

Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis

(2009) Steve S. Choi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Elevated Expression of Osteopontin May Be Related to Adipose Tissue Macrophage Accumulation and Liver Steatosis in Morbid Obesity

(2008) A. Bertola et al.   DIABETES

Hedgehog: functions and mechanisms

(2008) M. Varjosalo et al.   GENES & DEVELOPMENT

Alpha-1 adrenergic receptor transactivates signal transducer and activator of transcription-3 (Stat3) through activation of Src and epidermal growth factor receptor (EGFR) in hepatocytes

(2008) Chang Han et al.   JOURNAL OF CELLULAR PHYSIOLOGY