Dietary lipophilic iron alters amyloidogenesis and microglial morphology in Alzheimer's disease knock-in APP mice

Altered peripheral profile of blood cells in Alzheimer disease

(2017) Si-Han Chen et al.   MEDICINE

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

(2017) Rebecca Sims et al.   NATURE GENETICS

Brain Metal Distribution and Neuro-Inflammatory Profiles after Chronic Vanadium Administration and Withdrawal in Mice

(2017) Oluwabusayo R. Folarin et al.   Frontiers in Neuroanatomy

Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy

(2017) Kevin A. Clayton et al.   Frontiers in Neuroscience

Three-Dimensional Tomographic Imaging and Characterization of Iron Compounds within Alzheimer's Plaque Core Material

(2017) Joanna F. Collingwood et al.   JOURNAL OF ALZHEIMERS DISEASE

Increased Iron and Free Radical Generation in Preclinical Alzheimer Disease and Mild Cognitive Impairment

(2017) Mark A. Smith et al.   JOURNAL OF ALZHEIMERS DISEASE

Characterizing microglia activation: a spatial statistics approach to maximize information extraction

(2017) Benjamin M. Davis et al.   Scientific Reports

Enhanced Histochemical Detection of Iron in Paraffin Sections of Mouse Central Nervous System Tissue

(2016) Scott A. Sands et al.   ASN Neuro

Microglia show altered morphology and reduced arborization in human brain during aging and Alzheimer's disease

(2016) Danielle S. Davies et al.   BRAIN PATHOLOGY

Patterns of Brain Iron Accumulation in Vascular Dementia and Alzheimer’s Dementia Using Quantitative Susceptibility Mapping Imaging

(2016) Yeonsil Moon et al.   JOURNAL OF ALZHEIMERS DISEASE

Cognitive deficits in single App knock-in mouse models

(2016) Akira Masuda et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Laser ablation-inductively coupled plasma-mass spectrometry imaging of white and gray matter iron distribution in Alzheimer's disease frontal cortex

(2016) Dominic J. Hare et al.   NEUROIMAGE

A combination of an iron chelator with an antioxidant effectively diminishes the dendritic loss, tau-hyperphosphorylation, amyloids-β accumulation and brain mitochondrial dynamic disruption in rats with chronic iron-overload

(2016) Jirapas Sripetchwandee et al.   NEUROSCIENCE

Quantitative analysis of co-oligomer formation by amyloid-beta peptide isoforms

(2016) Marija Iljina et al.   Scientific Reports

Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice culture model

(2016) Sinead Healy et al.   Scientific Reports

Colocalization of cerebral iron with Amyloid beta in Mild Cognitive Impairment

(2016) J. M. G. van Bergen et al.   Scientific Reports

Activated iron-containing microglia in the human hippocampus identified by magnetic resonance imaging in Alzheimer disease

(2015) Michael M. Zeineh et al.   NEUROBIOLOGY OF AGING

Oral iron acutely elevates bacterial growth in human serum

(2015) James H. Cross et al.   Scientific Reports

Cortical iron regulation and inflammatory response in Alzheimer's disease and APPSWE/PS1ΔE9 mice: a histological perspective

(2015) Mark D. Meadowcroft et al.   Frontiers in Neuroscience

Disease-related microglia heterogeneity in the hippocampus of Alzheimer’s disease, dementia with Lewy bodies, and hippocampal sclerosis of aging

(2015) Adam D Bachstetter et al.   Acta Neuropathologica Communications

Quantitative Analysis of Histological Staining and Fluorescence Using ImageJ

(2014) Ellen C. Jensen   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Evidence of Redox-Active Iron Formation Following Aggregation of Ferrihydrite and the Alzheimer’s Disease Peptide β-Amyloid

(2014) James Everett et al.   INORGANIC CHEMISTRY

Energetic and nutritional constraints on infant brain development: Implications for brain expansion during human evolution

(2014) Stephen C. Cunnane et al.   JOURNAL OF HUMAN EVOLUTION

Gestational Iron Deficiency Differentially Alters the Structure and Function of White and Gray Matter Brain Regions of Developing Rats

(2014) Allison R. Greminger et al.   JOURNAL OF NUTRITION

Iron Supplementation in Infancy Contributes to More Adaptive Behavior at 10 Years of Age

(2014) Betsy Lozoff et al.   JOURNAL OF NUTRITION

Ferrous iron formation following the co-aggregation of ferric iron and the Alzheimer's disease peptide  -amyloid (1-42)

(2014) J. Everett et al.   Journal of the Royal Society Interface

An anemia of Alzheimer's disease

(2014) N G Faux et al.   MOLECULAR PSYCHIATRY

Single App knock-in mouse models of Alzheimer's disease

(2014) Takashi Saito et al.   NATURE NEUROSCIENCE

Iron overload accelerates neuronal amyloid-β production and cognitive impairment in transgenic mice model of Alzheimer's disease

(2014) Javier Becerril-Ortega et al.   NEUROBIOLOGY OF AGING

TNF and Increased Intracellular Iron Alter Macrophage Polarization to a Detrimental M1 Phenotype in the Injured Spinal Cord

(2014) Antje Kroner et al.   NEURON

The effect of iron in MRI and transverse relaxation of amyloid-beta plaques in Alzheimer's disease

(2014) Mark D. Meadowcroft et al.   NMR IN BIOMEDICINE

β-Amyloid Precursor Protein Does Not Possess Ferroxidase Activity but Does Stabilize the Cell Surface Ferrous Iron Exporter Ferroportin

(2014) Bruce X. Wong et al.   PLoS One

A mutation in the HFE gene is associated with altered brain iron profiles and increased oxidative stress in mice

(2013) Wint Nandar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Alzheimer's Aβ42 and Aβ40 peptides form interlaced amyloid fibrils

(2013) Lei Gu et al.   JOURNAL OF NEUROCHEMISTRY

A quantitative spatiotemporal analysis of microglia morphology during ischemic stroke and reperfusion

(2013) Helena W Morrison et al.   Journal of Neuroinflammation

Ferritin light chain interacts with PEN-2 and affects γ-secretase activity

(2013) Xinxin Li et al.   NEUROSCIENCE LETTERS

Kinetic studies of inhibition of the amyloid beta (1–42) aggregation using a ferrocene-tagged β-sheet breaker peptide

(2012) Lin Zhang et al.   ANALYTICAL BIOCHEMISTRY

Three-Dimensional Atlas of Iron, Copper, and Zinc in the Mouse Cerebrum and Brainstem

(2012) Dominic J. Hare et al.   ANALYTICAL CHEMISTRY

Multimodal MRI Analysis of the Corpus Callosum Reveals White Matter Differences in Presymptomatic and Early Huntington's Disease

(2012) M. Di Paola et al.   CEREBRAL CORTEX

Interplay between α-, β-, and γ-Secretases Determines Biphasic Amyloid-β Protein Level in the Presence of a γ-Secretase Inhibitor

(2012) Fernando Ortega et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain

(2012) Chuang Guo et al.   NEUROCHEMISTRY INTERNATIONAL

Structural Basis for Increased Toxicity of Pathological Aβ42:Aβ40Ratios in Alzheimer Disease

(2011) Kris Pauwels et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased cellular iron levels affect matrix metalloproteinase expression and phagocytosis in activated microglia

(2011) Nootchanat Mairuae et al.   NEUROSCIENCE LETTERS

Three-dimensional elemental bio-imaging of Fe, Zn, Cu, Mn and P in a 6-hydroxydopamine lesioned mouse brain

(2010) Dominic J. Hare et al.   Metallomics

Increased brain iron coincides with early plaque formation in a mouse model of Alzheimer's disease

(2010) Andreana C. Leskovjan et al.   NEUROIMAGE

MRI and histological analysis of beta-amyloid plaques in both human Alzheimer's disease and APP/PS1 transgenic mice

(2009) Mark D. Meadowcroft et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING