IRE1α inhibition decreased TXNIP/NLRP3 inflammasome activation through miR-17-5p after neonatal hypoxic–ischemic brain injury in rats

Intranasal Administration of Interferon Beta Attenuates Neuronal Apoptosis via the JAK1/STAT3/BCL-2 Pathway in a Rat Model of Neonatal Hypoxic-Ischemic Encephalopathy

(2016) Brandon J. Dixon et al.   ASN Neuro

Endoplasmic reticulum pathology and stress response in neurons precede programmed necrosis after neonatal hypoxia-ischemia

(2016) Raul Chavez-Valdez et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

MicroRNA-17 regulates autophagy to promote hepatic ischemia/reperfusion injury via suppression of signal transductions and activation of transcription-3 expression

(2016) Shipeng Li et al.   LIVER TRANSPLANTATION

IRE1α pathway of endoplasmic reticulum stress induces neuronal apoptosis in the locus coeruleus of rats under single prolonged stress

(2016) Wei Zhao et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Upregulated miR-17 Regulates Hypoxia-Mediated Human Pulmonary Artery Smooth Muscle Cell Proliferation and Apoptosis by Targeting Mitofusin 2

(2016) Zheng Lu et al.   MEDICAL SCIENCE MONITOR

G-CSF ameliorates neuronal apoptosis through GSK-3β inhibition in neonatal hypoxia–ischemia in rats

(2015) Li Li et al.   EXPERIMENTAL NEUROLOGY

Activation of Dopamine D2 Receptor Suppresses Neuroinflammation Through αB-Crystalline by Inhibition of NF-κB Nuclear Translocation in Experimental ICH Mice Model

(2015) Yang Zhang et al.   STROKE

By Targeting Stat3 microRNA-17-5p Promotes Cardiomyocyte Apoptosis in Response to Ischemia Followed by Reperfusion

(2014) Weijie Du et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Increased autophagy reduces endoplasmic reticulum stress after neonatal hypoxia–ischemia: Role of protein synthesis and autophagic pathways

(2014) Silvia Carloni et al.   EXPERIMENTAL NEUROLOGY

Delayed Remote Ischemic Postconditioning Improves Long Term Sensory Motor Deficits in a Neonatal Hypoxic Ischemic Rat Model

(2014) Pradilka N. Drunalini Perera et al.   PLoS One

The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease

(2013) E Mogilyansky et al.   CELL DEATH AND DIFFERENTIATION

mir-17–92 Cluster Is Required for and Sufficient to Induce Cardiomyocyte Proliferation in Postnatal and Adult Hearts

(2013) Jinghai Chen et al.   CIRCULATION RESEARCH

Computed microtomography visualization and quantification of mouse ischemic brain lesion by nonionic radio contrast agents

(2013) Marina Dobrivojević et al.   CROATIAN MEDICAL JOURNAL

MiR-17-92 cluster is a novel regulatory gene of cardiac ischemic/reperfusion injury

(2013) Mi Zhou et al.   MEDICAL HYPOTHESES

Activation of the miR-17 Family and miR-21 During Murine Kidney Ischemia-Reperfusion Injury

(2013) Tamás Kaucsár et al.   Nucleic Acid Therapeutics

MicroRNA Cluster miR-17-92 Regulates Neural Stem Cell Expansion and Transition to Intermediate Progenitors in the Developing Mouse Neocortex

(2013) Shan Bian et al.   Cell Reports

TXNIP Deficiency Exacerbates Endotoxic Shock via the Induction of Excessive Nitric Oxide Synthesis

(2013) Young-Jun Park et al.   PLoS Pathogens

MicroRNAs Regulate the Chaperone Network in Cerebral Ischemia

(2013) Yi-Bing Ouyang et al.   Translational Stroke Research

Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome

(2012) Christine M. Oslowski et al.   Cell Metabolism

TXNIP Switches Tracks toward a Terminal UPR

(2012) Tracy G. Anthony et al.   Cell Metabolism

IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

(2012) Alana G. Lerner et al.   Cell Metabolism

Prognostic significance of serum miR-17-5p in lung cancer

(2012) Qun Chen et al.   MEDICAL ONCOLOGY

MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles

(2012) Eva van Rooij et al.   NATURE REVIEWS DRUG DISCOVERY

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

IRE1  Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2

(2012) J.-P. Upton et al.   SCIENCE

Granulocyte-colony Stimulating Factor in Combination with Stem Cell Factor Confers Greater Neuroprotection after Hypoxic–Ischemic Brain Damage in the Neonatal Rats than a Solitary Treatment

(2012) Desislava Doycheva et al.   Translational Stroke Research

Splenic Immune Cells in Experimental Neonatal Hypoxia–Ischemia

(2012) Nancy Fathali et al.   Translational Stroke Research

Vascular Endothelial Growth Factors A and C are Induced in the SVZ Following Neonatal Hypoxia–Ischemia and Exert Different Effects on Neonatal Glial Progenitors

(2012) Jennifer M. Bain et al.   Translational Stroke Research

Amino-Functionalized Polystyrene Nanoparticles Activate the NLRP3 Inflammasome in Human Macrophages

(2011) Oleg Lunov et al.   ACS Nano

Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation

(2011) S. Jiang et al.   BLOOD

Transmembrane protein 166 regulates autophagic and apoptotic activities following focal cerebral ischemic injury in rats

(2011) Li Li et al.   EXPERIMENTAL NEUROLOGY

MicroRNA networks surrounding APP and amyloid-β metabolism — Implications for Alzheimer's disease

(2011) Nicole Schonrock et al.   EXPERIMENTAL NEUROLOGY

The developing oligodendrocyte: key cellular target in brain injury in the premature infant

(2011) Joseph J. Volpe et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Perinatal Acidosis and Hypoxic-Ischemic Encephalopathy in Preterm Infants of 33 to 35 Weeks’ Gestation

(2011) Lina F. Chalak et al.   JOURNAL OF PEDIATRICS

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Modulating stress responses by the UPRosome: A matter of life and death

(2011) Ute Woehlbier et al.   TRENDS IN BIOCHEMICAL SCIENCES

Prolonged Exposure to Isoflurane Ameliorates Infarction Severity in the Rat Pup Model of Neonatal Hypoxia-Ischemia

(2011) Hank Chen et al.   Translational Stroke Research

Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma

(2010) I. Papandreou et al.   BLOOD

Cyclooxygenase-2 inhibition provides lasting protection against neonatal hypoxic-ischemic brain injury*

(2010) Nancy Fathali et al.   CRITICAL CARE MEDICINE

Long-term evaluation of granulocyte-colony stimulating factor on hypoxic-ischemic brain damage in infant rats

(2010) Nancy Fathali et al.   INTENSIVE CARE MEDICINE

microRNAs in Inflammation

(2010) Enikö Sonkoly et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Vitamin D3Up-regulated Protein 1(VDUP1) Is Regulated by FOXO3A and miR-17-5p at the Transcriptional and Post-transcriptional Levels, Respectively, in Senescent Fibroblasts

(2010) De Xiang Zhuo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

MicroRNAs miR-17 and miR-20a Inhibit T Cell Activation Genes and Are Under-Expressed in MS Whole Blood

(2010) Mathew B. Cox et al.   PLoS One

Isoflurane Posttreatment Reduces Neonatal Hypoxic–Ischemic Brain Injury in Rats by the Sphingosine-1-Phosphate/Phosphatidylinositol-3-Kinase/Akt Pathway

(2010) Yilin Zhou et al.   STROKE

Remote Limb Ischemic Postconditioning Protects Against Neonatal Hypoxic–Ischemic Brain Injury in Rat Pups by the Opioid Receptor/Akt Pathway

(2010) Yilin Zhou et al.   STROKE

The MicroRNAs and Stroke: No Need to be Coded to be Counted

(2010) Raghu Vemuganti   Translational Stroke Research

MicroRNAs in Cerebral Ischemia

(2010) Kai-Ying Lim et al.   Translational Stroke Research

Glibenclamide improves neurological function in neonatal hypoxia–ischemia in rats

(2009) Yilin Zhou et al.   BRAIN RESEARCH

IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates

(2009) Dan Han et al.   CELL

Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis

(2009) Hong-li Yan et al.   EMBO JOURNAL

Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening

(2009) E K O Ng et al.   GUT

Matrix metalloproteinases inhibition provides neuroprotection against hypoxia-ischemia in the developing brain

(2009) Wanqiu Chen et al.   JOURNAL OF NEUROCHEMISTRY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Hypoxic-Ischemic Encephalopathy in Preterm Infants: Antecedent Factors, Brain Imaging, and Outcome

(2009) Pavithra Logitharajah et al.   PEDIATRIC RESEARCH

Antagomir-17-5p Abolishes the Growth of Therapy-Resistant Neuroblastoma through p21 and BIM

(2008) Laura Fontana et al.   PLoS One

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations

(2008) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cognitive maturation in preterm and term born adolescents

(2007) M Allin et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY