Article
Biophysics
Jihye Lee, Sandra Casale, Jessem Landoulsi, Clement Guibert
Summary: Despite decades of study, the process of calcium phosphate (CaP) biomineralisation is still not well understood due to its complex pathways regulated by biological parameters that are difficult to replicate. This study investigates the catalytic activity of enzymes in directing CaP crystallisation, inspired by the control of CaP biomineralisation in vivo through matrix vesicles (MVs) involving various proteins, including enzymes. The researchers demonstrate how enzymatic control influences the release of phosphate ions, enabling better manipulation of mineral formation, and how it offers insights into the role of magnesium ions as a crystallisation inhibitor.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Review
Engineering, Biomedical
Jue Wang, Zhihui Liu, Bingyu Ren, Qian Wang, Jia Wu, Nan Yang, Xin Sui, Lingfeng Li, Meihui Li, Xiao Zhang, Xinyue Li, Bowei Wang
Summary: Caries and dental erosion are common oral diseases. Biomimetic mineralisation is an ideal approach for restoring enamel, forming a new mineral layer that is tightly attached to the surface. This review highlights the application of various techniques in biomimetic mineralisation for enamel restoration.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2021)
Article
Engineering, Biomedical
Venkata Avadhanam, Ganesh Ingavle, Yishan Zheng, Sandeep Kumar, Christopher Liu, Susan Sandeman
Summary: A hydrogel polymer composite was developed as a synthetic substitute for the OOKP skirt, mimicking the alveo-dental lamina by incorporating nano-crystalline hydroxyapatite (nHAp) coated PLGA microspheres. The IPN hydrogel combinations supported cell adhesion and proliferation, while also showing non-inflammatory potential, making them promising materials for OOKP skirt substitutes.
JOURNAL OF BIOMATERIALS APPLICATIONS
(2021)
Review
Biochemistry & Molecular Biology
Krzysztof Stafin, Pawel Sliwa, Marek Piatkowski
Summary: The alveolar bone is a unique type of bone, and bone tissue engineering aims to develop methods for its regeneration. 3D-printed polycaprolactone (PCL) scaffolds, modified with hydroxyapatite (HA), type I collagen (CGI), or chitosan (CS), show high osteoinductive potential and can serve as alternatives to bone autografts.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Polymer Science
Fathia Rahmani, Omar Larbi Bouamrane, Amina Ben Bouabdallah, Leonard I. Atanase, Abdelkader Hellal, Aurelian Nichita Apintiliesei
Summary: Chitosan films coated with calcium phosphate were studied to mimic the formation of nanohydroxyapatite. Various testing methods confirmed the induction and control of the calcium phosphate coating. In addition, the antimicrobial activity of the phosphorylated derivatives of chitosan was evaluated, showing potential use as dental substitute materials.
Review
Engineering, Biomedical
Furqan A. Shah
Summary: Whitlockite, a unique calcium phosphate, is mainly found in pathological calcification of soft tissues. Despite claims in the synthetic bioceramics community, evidence suggests that it is exclusively a pathological biomineral and does not constitute a biomimetic strategy for bone repair.
ACTA BIOMATERIALIA
(2021)
Article
Materials Science, Multidisciplinary
S. Brahimi, A. Ressler, K. Boumchedda, M. Hamidouche, A. Kenzour, R. Djafar, M. Antunovic, L. Bauer, P. Hvizdos, H. Ivankovic
Summary: This study prepared highly porous chitosan/hydroxyapatite biocomposite scaffolds using the freeze-gelation method, demonstrating good biocompatibility and potential for use as scaffolding materials in bone tissue engineering.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Chemistry, Applied
Joao P. Ribeiro, Rui M. A. Domingues, Pedro S. Babo, Liebert P. Nogueira, Janne E. Reseland, Rui L. Reis, Manuel Gomez-Florit, Manuela E. Gomes
Summary: Mineralized nanocomposite scaffolds can mimic bone ECM properties and have the potential to promote both osteogenesis and angiogenesis.
CARBOHYDRATE POLYMERS
(2022)
Article
Engineering, Biomedical
Julia B. Cassel, Matheus C. Tronco, Beatriz A. de Melo, Fernanda dos Santos de Oliveira, Luis A. L. dos Santos
Summary: Bone defects in patients have become increasingly important in the development of disability in recent decades, affecting their quality of life. Surgical intervention is often necessary for large bone defects that have a low chance of self-repair. The use of α-TCP-based cements in minimally invasive procedures is being studied as a potential solution. However, these cements lack adequate mechanical properties for most orthopedic applications.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Physiology
Michael J. Hubbard, Jonathan E. Mangum, Vidal A. Perez, Rebecca Williams
Summary: Molar hypomineralisation, also known as chalky teeth, affects over 1-in-5 children worldwide and is associated with childhood illness. Recent biochemical studies have provided insights into the pathomechanism of this condition, offering potential for improved clinical management and prevention strategies. This breakthrough opens up new avenues for research into the causation and pathogenesis of MH, with the aim of ultimately leading to medical prevention and significant reductions in childhood tooth decay globally.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Pradhyut Rajkumar, Bimal K. Sarma
Summary: The crystal growth and manipulation of hydroxyapatite films on different substrates were studied. It was found that the structure and morphology of the hydroxyapatite films depended on the growth duration, substrate type, and post-deposition annealing of the substrates. Titanium induced greater crystallinity in hydroxyapatite, while sputtered ZnO thin films caused reduced crystallinity. The thickness of hydroxyapatite increased with deposition time regardless of the substrate.
MATERIALS CHARACTERIZATION
(2022)
Article
Chemistry, Physical
Jooseong Kim, Sukyoung Kim, Inhwan Song
Summary: This study compared the bone regeneration capacity of OCP products with two commonly used materials and found that OCP showed significantly higher resorption and new bone formation. OCP bone substitutes can enhance bone regeneration significantly by activating osteoblasts and a rapid phase transition of OCP crystals to biological apatite crystals (mineralization), as well as providing additional space for new bone formation by rapid resorption.
Article
Polymer Science
Ziyu Gao, Layla Hassouneh, Xuebin Yang, Juan Pang, Paul D. Thornton, Giuseppe Tronci
Summary: A non-toxic and simple acellular method was reported to generate specific hydrogen phosphate interactions within the polymer network of cystamine-crosslinked hyaluronic acid hydrogels. The reinforced dual crosslinked hydrogel networks after 4-week incubation in disodium phosphate-supplemented solutions notably enabled the mineralisation of hydroxyapatite crystals across the entire hydrogel structure. The presence of hydrogen phosphate-cystamine-crosslinked hyaluronic acid hydrogen bond interactions proved to be crucial for acellular hydrogel mineralisation in simulated body fluid, showcasing significant potential for accelerated hard tissue repair in vivo.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Engineering, Biomedical
Meadhbha Brennan, David S. Monahan, Benedicte Brulin, Sara Gallinetti, Paul Humbert, Christina Tringides, Cristina Canal, Maria Pau Ginebra, Pierre Layrolle
Summary: In this study, the healing capacity of CDHA administering MSCs to bone defects was evaluated for the first time and compared with sintered beta-TCP constructs. Greater cell infiltration occurred in CDHA scaffolds, and after 8 weeks in vivo, MSC engraftment was higher in CDHA compared to beta-TCP, as was bone in-growth.
ACTA BIOMATERIALIA
(2021)
Article
Biology
Caroline C. C. Mather, Heta M. M. Lampinen, Maurice Tucker, Matthias Leopold, Shawan Dogramaci, Mark Raven, Robert J. J. Gilkes
Summary: Microbial extracellular polymeric substances (EPS) and certain clay minerals can catalyze dolomite precipitation. This study found that EPS acts as a nucleation site for dolomite and clay minerals in groundwater dolocrete profiles, suggesting that similar mineralization processes may have occurred to form these dolocretes. These findings are important for understanding the microbial influence on mineralization in the environment.
Article
Geosciences, Multidisciplinary
Bin Zhang, Jiaqi Liu, Wen Chen, Zhiliang Zhang, Li Yang, Lei Zhang, Zeyang Zhu, Chunqing Sun, Zhihao Sun
Summary: The eastern Tibetan Plateau is a region with unique topography and active tectonics, making it crucial for studying geodynamics and lithosphere-atmosphere interaction. By integrating new and reported thermochronological data, as well as paleo-crustal thickness reconstruction, this study sheds light on the tectonic deformation, climate-tectonic coupling, and geodynamics of the area.
Article
Geosciences, Multidisciplinary
Zhenhua Tian, Shangwen Zhou, Songtao Wu, Sai Xu, Junping Zhou, Jianchao Cai
Summary: This paper presents a modified method for calculating the lost gas content of shale by analyzing the coring and on-site desorption processes. The method accurately depicts the loss characteristics of free and adsorbed gas and identifies parameters that influence the calculation of in-situ shale gas content. The results demonstrate that the method shows satisfactory applicability in gas loss curve prediction and in-situ gas content estimation.
Article
Geosciences, Multidisciplinary
Pengcheng Li, Jaffar Abbas, Daniel Balsalobre-Lorente, Qingren Wang, Qianxiao Zhang, Syed Ale Raza Shah
Summary: This study explores the factors contributing to sustainability in Pakistan from 1974 to 2018 and finds that emissions from industrial and agriculture sectors have significantly decreased, while the financial sector has not effectively reduced environmental pressure. Therefore, Pakistan needs to adjust its economic policies and ensure the green allocation of financial resources.
Article
Geosciences, Multidisciplinary
Shi Zhou, Ting Zhou, Duo Guan, Yong Yao, Huimin Sun, Ahmed Ali Mosa, Yajie Zuo, Xianqiang Yin
Summary: Graphitic carbon nitride (g-C3N4) has been widely used due to its excellent optical properties and physicochemical stability. The risk of g-C3N4 transport in the environment has been overlooked, but this study investigated its transport behavior in various media. The results showed that flow rate and ionic strength influenced the transport, and the presence of lead (Pb) affected the outflow of g-C3N4. The unique structure of g-C3N4 particles allowed them to deposit in certain media and act as carriers for Pb release.
Article
Geosciences, Multidisciplinary
Xiaolong Qiao, Muntasir Murshed, Mohammad Mahtab Alam, Narasingha Das, Kurshid Khudoykulov, Salman Tariq
Summary: This study examines how macroeconomic factors influence India's carbon emission intensity levels and confirms the impact of factors such as foreign remittance receipts, energy consumption, urbanization, and technological progress. The findings provide policy recommendations for India's carbon emission reduction targets.
Article
Geosciences, Multidisciplinary
Wei Liu, Bo Wan
Summary: Magmatic-hydrothermal systems play a crucial role in transporting materials and potentially affecting Earth's long-term environment. This study investigates the duration of prograde metamorphism induced by fluid infiltration and the amount of carbon released by skarn ore deposits. The findings reveal that skarn ore deposits can efficiently decarbonize CO2 at a high rate, surpassing volcanism in different tectonic settings. The CO2 flux of skarn deposits increases over time and reaches a maximum value at the J/K boundary, providing an important previously unquantified source of outgassing in the subduction zone.
Article
Geosciences, Multidisciplinary
Haikuan Nie, Pei Li, Qing Chen, Zhijun Jin, Quanyou Liu, Wei Dang, Qian Chen, Jianghui Ding, Changbo Zhai
Summary: This study investigates the shale quality and shale gas potential in the upper Ordovician to lower Silurian formations in the Sichuan Basin of southern China. The distribution and characteristics of organic-rich shale are analyzed, aiding in the assessment of shale gas potential and identification of sweet spots.
Article
Geosciences, Multidisciplinary
Najia Saqib, Shujaat Abbas, Ilhan Ozturk, Muntasir Murshed, Malgorzata Tarczynska-Luniewska, Mohammad Mahtab Alam, Waldemar Tarczynski
Summary: This study examines the impact of economic growth, financial development, eco-friendly ICT, renewable energy, and human capital on lowering carbon footprint in the world's top polluting economies from 1993 to 2020. The findings suggest that eco-friendly ICT has the potential to effectively alleviate pollution, and financial development, renewable energy, and environmental technology are proposed as potential solutions for reducing carbon emissions.
Article
Geosciences, Multidisciplinary
Hikmat Salam, Syed Ali Turab, Asghar Ali, M. Qasim Jan, Norasiah Sulaiman, Mohd Basril Iswadi Basori
Summary: The Kahi melange complex in NW Pakistan is an important record of the tectonic evolution between the Indian plate and the Afghan block, consisting of highly dismembered ophiolitic and sedimentary units.
Article
Geosciences, Multidisciplinary
Er-Kun Xue, Wei Wang, David Chew, Manoj K. Pandit, Xin Deng, Yang Tian, Xi-Run Tong, Jun-Hong Zhao
Summary: The study reveals the presence of water-fluxed melting during the Wuyi-Yunkai Orogeny in South China. These water-fluxed melting quartzo-feldspathic migmatites formed during the early Paleozoic and were melted through reactions involving water-saturated quartz, feldspar, biotite, and K-feldspar. The findings highlight the significance of water-fluxed anatexis in the differentiation of the continental crust during orogenesis.
Article
Geosciences, Multidisciplinary
Hadi Shafaii Moghadam, Qiu-Li Li, William L. Griffin, Xian-Hua Li, Orhan Karsli, Christopher J. Spencer, Jose F. Santos, Maria Kirchenbaur, Sobhi Nasir, Suzanne Y. O'Reilly
Summary: Understanding the crustal growth, reworking, and geodynamics of the northern continental margin of Gondwana during the Ediacaran to Silurian times is crucial for the paleogeographic reconstruction of Gondwana. This study uses various analytical methods to evaluate the magmatic history of this region and obtain relevant detrital zircon data. The results provide valuable insights into the crustal evolution and tectonic activities in the northern Gondwana region.
Article
Geosciences, Multidisciplinary
Laura Petrescu, Felix Borleanu, Emanuel Kaestle, Randell Stephenson, Anica Placinta, Oleksandr Ivanovich Liashchuk
Summary: This study investigates the seismic structure of the Eastern European lithosphere and the transition from Precambrian to Phanerozoic Europe. The results show that the crust thickens across the Trans European Suture Zone boundary and the mantle is seismically faster beneath younger terranes. The Precambrian building blocks exhibit contrasting seismic fabrics, with the Baltic orogens characterized by uniform crust and the Sarmatia region showing alternating high and low velocity layers.
Article
Geosciences, Multidisciplinary
Dongya Zou, Hongfu Zhang
Summary: This study analyzes the U-Pb-Hf-O isotopes of zircons in felsic granulite xenoliths from the Fuxin late Cretaceous basalts in the North China Craton to evaluate the role of magma underplating in modifying the Archean lower crust. The results show that long-lived magma underplating occurred beneath the Fuxin region during the Mesozoic, with underplated magmas originating from the lithospheric mantle and later from the depleted asthenospheric mantle. This study concludes that magma underplating not only provided heat for remelting, but also added exotic material and weakened the lower crust, leading to its destruction.
Article
Geosciences, Multidisciplinary
Yu Han, Yingchang Cao, Chao Liang, Keyu Liu, Fang Hao
Summary: A paleoclimate reconstruction based on high-resolution records from lacustrine shale in the Bohai Bay Basin reveals a shift in orbital variability and a humidification event at -41.9 Ma in East Asia. The intensification of the East Asian monsoons at this time was likely a response to the elevated atmospheric pCO2 during the concurrent global warming.
Article
Geosciences, Multidisciplinary
Francesca Innocenzi, Sara Ronca, Stephen Foley, Samuele Agostini, Michele Lustrino
Summary: This study investigates two volcanic provinces in the western branch of the East African Rift and finds that the volcanic products show wide variability in chemical and mineralogical characteristics. Petrographic and geochemical analysis reveals enriched and heterogeneous sub-lithospheric mantle sources. The differences in isotopic features between the two volcanic provinces may indicate changes in the composition, mineralogy, and depth of melting in the lithospheric mantle source.