Contribution of Adipose-Derived Factor D/Adipsin to Complement Alternative Pathway Activation: Lessons from Lipodystrophy

Analysis of Factor D Isoforms in Malpuech–Michels–Mingarelli–Carnevale Patients Highlights the Role of MASP-3 as a Maturase in the Alternative Pathway of Complement

(2017) Rasmus Pihl et al.   JOURNAL OF IMMUNOLOGY

The Alternative Pathway of Complement and the Evolving Clinical-Pathophysiological Spectrum of Atypical Hemolytic Uremic Syndrome

(2016) Bruce E. Berger   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Small-molecule factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome

(2016) Xuan Yuan et al.   HAEMATOLOGICA

Small-molecule factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome

(2016) Xuan Yuan et al.   HAEMATOLOGICA

MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked

(2016) József Dobó et al.   Scientific Reports

Rare genetic variants in the CFI gene are associated with advanced age-related macular degeneration and commonly result in reduced serum factor I levels

(2015) D. Kavanagh et al.   HUMAN MOLECULAR GENETICS

MASP-1 and MASP-2 Do Not Activate Pro–Factor D in Resting Human Blood, whereas MASP-3 Is a Potential Activator: Kinetic Analysis Involving Specific MASP-1 and MASP-2 Inhibitors

(2015) Gábor Oroszlán et al.   JOURNAL OF IMMUNOLOGY

What's the matter with MAT? Marrow adipose tissue, metabolism, and skeletal health

(2014) Erica L. Scheller et al.   Annals of the New York Academy of Sciences

Adipsin Is an Adipokine that Improves β Cell Function in Diabetes

(2014) James C. Lo et al.   CELL

Properdin Plays a Protective Role in Polymicrobial Septic Peritonitis

(2014) C. M. Stover et al.   JOURNAL OF IMMUNOLOGY

Genetic variants in the complement system predisposing to age-related macular degeneration: A review

(2014) Elizabeth C. Schramm et al.   MOLECULAR IMMUNOLOGY

A PHASE IA DOSE-ESCALATION STUDY OF THE ANTI-FACTOR D MONOCLONAL ANTIBODY FRAGMENT FCFD4514S IN PATIENTS WITH GEOGRAPHIC ATROPHY

(2013) Diana V. Do et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Transcriptional Control of Adipose Lipid Handling by IRF4

(2011) Jun Eguchi et al.   Cell Metabolism

DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes

(2011) Charles A. Harris et al.   JOURNAL OF LIPID RESEARCH

Essential role of Mannose-binding lectin-associated serine protease-1 in activation of the complement factor D

(2009) Minoru Takahashi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

(2009) Chunlei Wu et al.   GENOME BIOLOGY

A Functional Peroxisome Proliferator-activated Receptor-γ Ligand-binding Domain Is Not Required for Adipogenesis

(2008) Christopher J. Walkey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY