REDD1/Autophagy Pathway Is Associated with Neutrophil-Driven IL-1β Inflammatory Response in Active Ulcerative Colitis

Inflammatory hypoxia induces syndecan-2 expression through IL-1β–mediated FOXO3a activation in colonic epithelia

(2017) Sojoong Choi et al.   FASEB JOURNAL

Regulated in development and DNA damage responses 1 (REDD1) links stress with IL-1β–mediated familial Mediterranean fever attack through autophagy-driven neutrophil extracellular traps

(2017) Panagiotis Skendros et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 2: Current Management

(2017) Marcus Harbord et al.   Journal of Crohns & Colitis

Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, Diagnosis, Extra-intestinal Manifestations, Pregnancy, Cancer Surveillance, Surgery, and Ileo-anal Pouch Disorders

(2017) Fernando Magro et al.   Journal of Crohns & Colitis

Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome

(2017) Viola Neudecker et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interferon lambda1/IL-29 and inorganic polyphosphate are novel regulators of neutrophil-driven thromboinflammation

(2017) Akrivi Chrysanthopoulou et al.   JOURNAL OF PATHOLOGY

Ulcerative colitis

(2017) Ryan Ungaro et al.   LANCET

Erratum: Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor–neutralizing therapy in patients with inflammatory bowel disease

(2017) Nathaniel R West et al.   NATURE MEDICINE

An emerging role for neutrophil extracellular traps in noninfectious disease

(2017) Selina K Jorch et al.   NATURE MEDICINE

NETopathies? Unraveling the Dark Side of Old Diseases through Neutrophils

(2017) Alexandros Mitsios et al.   Frontiers in Immunology

Implication of REDD1 in the activation of inflammatory pathways

(2017) Faustine Pastor et al.   Scientific Reports

Histological Disease Activity as a Predictor of Clinical Relapse Among Patients With Ulcerative Colitis: Systematic Review and Meta-Analysis

(2016) Sunhee Park et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Psychological stress promotes neutrophil infiltration in colon tissue through adrenergic signaling in DSS-induced colitis model

(2016) Que Deng et al.   BRAIN BEHAVIOR AND IMMUNITY

Autophagy: controlling cell fate in rheumatic diseases

(2016) Jason S. Rockel et al.   Nature Reviews Rheumatology

Is REDD1 a Metabolic Éminence Grise ?

(2016) Christopher Lipina et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Flow cytometric assay for direct quantification of neutrophil extracellular traps in blood samples

(2015) Mathilde Gavillet et al.   AMERICAN JOURNAL OF HEMATOLOGY

Expression of functional tissue factor by neutrophil extracellular traps in culprit artery of acute myocardial infarction

(2015) Dimitrios A. Stakos et al.   EUROPEAN HEART JOURNAL

The gut microbiota and host health: a new clinical frontier

(2015) Julian R Marchesi et al.   GUT

Neutrophil Extracellular Traps in Ulcerative Colitis

(2015) Tue Bjerg Bennike et al.   INFLAMMATORY BOWEL DISEASES

Immunopathogenesis of IBD: current state of the art

(2015) Heitor S. P. de Souza et al.   Nature Reviews Gastroenterology & Hepatology

A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity

(2015) Shuxi Qiao et al.   Nature Communications

Neutrophil extracellular traps regulate IL-1β-mediated inflammation in familial Mediterranean fever

(2014) Eirini Apostolidou et al.   ANNALS OF THE RHEUMATIC DISEASES

Comparing histological activity indexes in UC

(2014) Aude Bressenot et al.   GUT

C5a and TNF-  Up-Regulate the Expression of Tissue Factor in Intra-Alveolar Neutrophils of Patients with the Acute Respiratory Distress Syndrome

(2014) K. Kambas et al.   JOURNAL OF IMMUNOLOGY

Clinical significance of expression of tissue factor and tissue factor pathway inhibitor in ulcerative colitis

(2014) Hao-Lan He   WORLD JOURNAL OF GASTROENTEROLOGY

Inflammatory bowel disease and thromboembolism

(2014) Petros Zezos   WORLD JOURNAL OF GASTROENTEROLOGY

Tissue factor expression in neutrophil extracellular traps and neutrophil derived microparticles in antineutrophil cytoplasmic antibody associated vasculitis may promote thromboinflammation and the thrombophilic state associated with the disease

(2013) Konstantinos Kambas et al.   ANNALS OF THE RHEUMATIC DISEASES

The Role of Polymorphonuclear Leukocyte Trafficking in the Perpetuation of Inflammation During Inflammatory Bowel Disease

(2013) Jennifer C. Brazil et al.   INFLAMMATORY BOWEL DISEASES

Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury

(2012) Axelle Caudrillier et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil Extracellular Traps: Double-Edged Swords of Innate Immunity

(2012) M. J. Kaplan et al.   JOURNAL OF IMMUNOLOGY

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

Neutrophil Extracellular Traps Directly Induce Epithelial and Endothelial Cell Death: A Predominant Role of Histones

(2012) Mona Saffarzadeh et al.   PLoS One

Long pentraxin 3 (PTX3) expression and release by neutrophils in vitro and in ulcerative colitis

(2011) Alexander S. Savchenko et al.   PATHOLOGY INTERNATIONAL

The multivalent activity of the tissue factor–thrombin pathway in thrombotic and non-thrombotic disorders as a target for therapeutic intervention

(2010) Ioannis Mitroulis et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

TNF  is a key mediator of the pronociceptive effects of mucosal supernatant from human ulcerative colitis on colonic DRG neurons

(2010) C. Ibeakanma et al.   GUT

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Hypoxia regulates TSC1/2 mTOR signaling and tumor suppression through REDD1-mediated 14 3 3 shuttling

(2008) M. P. DeYoung et al.   GENES & DEVELOPMENT