Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome

Interleukin 1β Mediates Intestinal Inflammation in Mice and Patients With Interleukin 10 Receptor Deficiency

(2016) Dror S. Shouval et al.   GASTROENTEROLOGY

Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis

(2015) Roni Nowarski et al.   CELL

Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury

(2015) Sang-Uk Seo et al.   IMMUNITY

Assessment of Circulating MicroRNAs for the Diagnosis and Disease Activity Evaluation in Patients with Ulcerative Colitis by Using the Nanostring Technology

(2015) Christos Polytarchou et al.   INFLAMMATORY BOWEL DISEASES

Neutrophil IL-1β Processing Induced by Pneumolysin Is Mediated by the NLRP3/ASC Inflammasome and Caspase-1 Activation and Is Dependent on K+Efflux

(2015) Mausita Karmakar et al.   JOURNAL OF IMMUNOLOGY

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

MicroRNA-223 Regulates the Differentiation and Function of Intestinal Dendritic Cells and Macrophages by Targeting C/EBPβ

(2015) Haibo Zhou et al.   Cell Reports

Inflammasome activation has an important role in the development of spontaneous colitis

(2014) J Zhang et al.   Mucosal Immunology

Non-redundant properties of IL-1α and IL-1β during acute colon inflammation in mice

(2013) Marina Bersudsky et al.   GUT

The Role of Polymorphonuclear Leukocyte Trafficking in the Perpetuation of Inflammation During Inflammatory Bowel Disease

(2013) Jennifer C. Brazil et al.   INFLAMMATORY BOWEL DISEASES

MicroRNA-223 controls susceptibility to tuberculosis by regulating lung neutrophil recruitment

(2013) Anca Dorhoi et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-223: infection, inflammation and cancer

(2013) M. Haneklaus et al.   JOURNAL OF INTERNAL MEDICINE

Nlrp3 activation in the intestinal epithelium protects against a mucosal pathogen

(2013) G X Song-Zhao et al.   Mucosal Immunology

Treatment of HCV Infection by Targeting MicroRNA

(2013) Harry L.A. Janssen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease

(2013) Loris R. Lopetuso et al.   Frontiers in Immunology

New insights into the dichotomous role of innate cytokines in gut homeostasis and inflammation

(2012) Giorgos Bamias et al.   CYTOKINE

Ly6Chi Monocytes in the Inflamed Colon Give Rise to Proinflammatory Effector Cells and Migratory Antigen-Presenting Cells

(2012) Ehud Zigmond et al.   IMMUNITY

Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver

(2012) Shu-hao Hsu et al.   JOURNAL OF CLINICAL INVESTIGATION

NLRP3 Inflammasome Activity Is Negatively Controlled by miR-223

(2012) F. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: miR-223 and EBV miR-BART15 Regulate the NLRP3 Inflammasome and IL-1  Production

(2012) M. Haneklaus et al.   JOURNAL OF IMMUNOLOGY

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

(2012) Jorge Henao-Mejia et al.   NATURE

The mammalian microRNA response to bacterial infections

(2012) Ana Eulalio et al.   RNA Biology

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils

(2011) Arun K. Mankan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Selective Upregulation of microRNA Expression in Peripheral Blood Leukocytes in IL-10-/- Mice Precedes Expression in the Colon

(2011) J. S. Schaefer et al.   JOURNAL OF IMMUNOLOGY

Interleukin 37 expression protects mice from colitis

(2011) E. N. McNamee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Nlrp3 inflammasome: contributions to intestinal homeostasis

(2011) Md. Hasan Zaki et al.   TRENDS IN IMMUNOLOGY

Enhand secretion of tumour necrosis factor-alpha, IL-6, and IL-1β by isolated lamina ropria monouclear cells from patients with ulcretive cilitis and Crohn's disease

(2010) H.-C. REINECKER et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

(2010) C. Bauer et al.   GUT

The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis

(2010) Md. Hasan Zaki et al.   IMMUNITY

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

(2010) Irving C. Allen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MicroRNAs modulate the noncanonical transcription factor NF-κB pathway by regulating expression of the kinase IKKα during macrophage differentiation

(2010) Tao Li et al.   NATURE IMMUNOLOGY

Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia

(2009) J. A. Pulikkan et al.   BLOOD

Novel model of TH2-polarized chronic ileitis: The SAMP1 mouse

(2009) Eoin N. McNamee et al.   INFLAMMATORY BOWEL DISEASES

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

(2008) Jonathan B. Johnnidis et al.   NATURE

Stable knockdown of microRNA in vivo by lentiviral vectors

(2008) Bernhard Gentner et al.   NATURE METHODS