The long and the short of it – a perspective on peptidergic regulation of circuits and behaviour

New techniques, applications and perspectives in neuropeptide research

(2018) Kellen DeLaney et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Evolution of neuropeptide signalling systems

(2018) Maurice R. Elphick et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Hidden female physiological resistance to male accessory gland substances in a simultaneous hermaphrodite

(2017) Monica Lodi et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Spike and Neuropeptide-Dependent Mechanisms Control GnRH Neuron Nerve Terminal Ca 2+ over Diverse Time Scales

(2017) Karl J. Iremonger et al.   JOURNAL OF NEUROSCIENCE

IL-17 is a neuromodulator of Caenorhabditis elegans sensory responses

(2017) Changchun Chen et al.   NATURE

Temporally precise labeling and control of neuromodulatory circuits in the mammalian brain

(2017) Dongmin Lee et al.   NATURE METHODS

A molecular census of arcuate hypothalamus and median eminence cell types

(2017) John N Campbell et al.   NATURE NEUROSCIENCE

Functional consequences of neuropeptide and small-molecule co-transmission

(2017) Michael P. Nusbaum et al.   NATURE REVIEWS NEUROSCIENCE

Renal neuroendocrine control of desiccation and cold tolerance by Drosophila suzukii

(2017) Selim Terhzaz et al.   PEST MANAGEMENT SCIENCE

Evolutionarily conserved TRH neuropeptide pathway regulates growth inCaenorhabditis elegans

(2017) Elien Van Sinay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic and peptidergic connectome of a neurosecretory center in the annelid brain

(2017) Elizabeth A Williams et al.   eLife

Control of Neuropeptide Expression by Parallel Activity-dependent Pathways in Caenorhabditis elegans

(2017) Teresa Rojo Romanos et al.   Scientific Reports

An oxytocin-dependent social interaction between larvae and adult C. elegans

(2017) Euan Scott et al.   Scientific Reports

Identification of a neuropeptide precursor protein that gives rise to a “cocktail” of peptides that bind Cu(II) and generate metal-linked dimers

(2016) Christopher E. Jones et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

A Cortical Circuit for Sexually Dimorphic Oxytocin-Dependent Anxiety Behaviors

(2016) Kun Li et al.   CELL

Identification of a Peptidergic Pathway Critical to Satiety Responses in Drosophila

(2016) Soohong Min et al.   CURRENT BIOLOGY

Oxytocin mediated behavior in invertebrates: An evolutionary perspective

(2016) Meghan A. Lockard et al.   Developmental Neurobiology

A “Love” Dart Allohormone Identified in the Mucous Glands of Hermaphroditic Land Snails

(2016) Michael J. Stewart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

60 YEARS OF POMC: Biosynthesis, trafficking, and secretion of pro-opiomelanocortin-derived peptides

(2016) Niamh X Cawley et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Neuropeptide Y Impairs Retrieval of Extinguished Fear and Modulates Excitability of Neurons in the Infralimbic Prefrontal Cortex

(2016) L. L. Vollmer et al.   JOURNAL OF NEUROSCIENCE

Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes

(2016) Roman A Romanov et al.   NATURE NEUROSCIENCE

Adult mouse cortical cell taxonomy revealed by single cell transcriptomics

(2016) Bosiljka Tasic et al.   NATURE NEUROSCIENCE

Oxytocin Enhances Social Recognition by Modulating Cortical Control of Early Olfactory Processing

(2016) Lars-Lennart Oettl et al.   NEURON

Urbilaterian origin of paralogous GnRH and corazonin neuropeptide signalling pathways

(2016) Shi Tian et al.   Scientific Reports

Ionotropic Chemosensory Receptors Mediate the Taste and Smell of Polyamines

(2016) Ashiq Hussain et al.   PLOS BIOLOGY

Neuropeptides Modulate Female Chemosensory Processing upon Mating in Drosophila

(2016) Ashiq Hussain et al.   PLOS BIOLOGY

The Multilayer Connectome of Caenorhabditis elegans

(2016) Barry Bentley et al.   PLoS Computational Biology

Stereotyped responses of Drosophila peptidergic neuronal ensemble depend on downstream neuromodulators

(2016) Wilson Mena et al.   eLife

Synaptic transmission parallels neuromodulation in a central food-intake circuit

(2016) Philipp Schlegel et al.   eLife

The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cyclic Regulation of Sensory Perception by a Female Hormone Alters Behavior

(2015) Sandeepa Dey et al.   CELL

A Higher Brain Circuit for Immediate Integration of Conflicting Sensory Information in Drosophila

(2015) Laurence P.C. Lewis et al.   CURRENT BIOLOGY

Positional RNA-Seq identifies candidate genes for phenotypic engineering of sexual traits

(2015) Roberto Arbore et al.   Frontiers in Zoology

High-throughput spatial mapping of single-cell RNA-seq data to tissue of origin

(2015) Kaia Achim et al.   NATURE BIOTECHNOLOGY

Isoform-specific expression of the neuropeptide orcokinin in Drosophila melanogaster

(2015) Ji Chen et al.   PEPTIDES

Monoaminergic tone supports conductance correlations and stabilizes activity features in pattern generating neurons of the lobster, Panulirus interruptus

(2015) Wulf-Dieter Krenz et al.   Frontiers in Neural Circuits

Large-Scale Combinatorial Deorphanization of Platynereis Neuropeptide GPCRs

(2015) Philipp Bauknecht et al.   Cell Reports

Inter-individual stereotypy of the Platynereis larval visual connectome

(2015) Nadine Randel et al.   eLife

A serial multiplex immunogold labeling method for identifying peptidergic neurons in connectomes

(2015) Réza Shahidi et al.   eLife

Starvation promotes concerted modulation of appetitive olfactory behavior via parallel neuromodulatory circuits

(2015) Kang I Ko et al.   eLife

Male Seminal Fluid Substances Affect Sperm Competition Success and Female Reproductive Behavior in a Seed Beetle

(2015) Takashi Yamane et al.   PLoS One

The comprehensive analysis of DEG/ENaC subunits in Hydra reveals a large variety of peptide-gated channels, potentially involved in neuromuscular transmission

(2014) Marc Assmann et al.   BMC BIOLOGY

Oxytocin Modulates Female Sociosexual Behavior through a Specific Class of Prefrontal Cortical Interneurons

(2014) Miho Nakajima et al.   CELL

Receipt of Seminal Fluid Proteins Causes Reduction of Male Investment in a Simultaneous Hermaphrodite

(2014) Yumi Nakadera et al.   CURRENT BIOLOGY

Context-dependent modulation reconfigures interactive sensory-mediated microcircuits in Caenorhabditis elegans

(2014) Richard Komuniecki et al.   CURRENT OPINION IN NEUROBIOLOGY

Alternative delivery of male accessory gland products

(2014) Z Zizzari et al.   Frontiers in Zoology

Sphingosine-1-phosphate receptor 1 reporter mice reveal receptor activation sites in vivo

(2014) Mari Kono et al.   JOURNAL OF CLINICAL INVESTIGATION

Control of Food Intake and Energy Expenditure by Nos1 Neurons of the Paraventricular Hypothalamus

(2014) A. K. Sutton et al.   JOURNAL OF NEUROSCIENCE

A Homeostatic Sleep-Stabilizing Pathway in Drosophila Composed of the Sex Peptide Receptor and Its Ligand, the Myoinhibitory Peptide

(2014) Yangkyun Oh et al.   PLOS BIOLOGY

Relaxin-3/RXFP3 networks: an emerging target for the treatment of depression and other neuropsychiatric diseases?

(2014) Craig M. Smith et al.   Frontiers in Pharmacology

Family of FLP Peptides in Caenorhabditis elegans and Related Nematodes

(2014) Chris Li et al.   Frontiers in Endocrinology

The neuropeptide complement of the marine annelid Platynereis dumerilii

(2013) Markus Conzelmann et al.   BMC GENOMICS

Dopaminergic tone regulates transient potassium current maximal conductance through a translational mechanism requiring D1Rs, cAMP/PKA, Erk and mTOR

(2013) Edmund W Rodgers et al.   BMC NEUROSCIENCE

Serotonin and the Neuropeptide PDF Initiate and Extend Opposing Behavioral States in C. elegans

(2013) Steven W. Flavell et al.   CELL

Oxytocin Reduces Reward-Driven Food Intake in Humans

(2013) V. Ott et al.   DIABETES

Cortical interneurons that specialize in disinhibitory control

(2013) Hyun-Jae Pi et al.   NATURE

From the connectome to brain function

(2013) Cornelia I Bargmann et al.   NATURE METHODS

Endogenous mammalian RF-amide peptides, including PrRP, kisspeptin and 26RFa, modulate nociception and morphine analgesia via NPFF receptors

(2013) Khadija Elhabazi et al.   NEUROPHARMACOLOGY

Molecular evolution of peptidergic signaling systems in bilaterians

(2013) O. Mirabeau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cephalo-traumatic secretion transfer in a hermaphrodite sea slug

(2013) R. Lange et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The seminal symphony: how to compose an ejaculate

(2013) Jennifer C. Perry et al.   TRENDS IN ECOLOGY & EVOLUTION

Activation of high and low affinity dopamine receptors generates a closed loop that maintains a conductance ratio and its activity correlate

(2013) Wulf-Dieter C. Krenz et al.   Frontiers in Neural Circuits

Beyond the connectome: How neuromodulators shape neural circuits

(2012) Cornelia I. Bargmann   BIOESSAYS

Molecular Profiling of Activated Neurons by Phosphorylated Ribosome Capture

(2012) Zachary A. Knight et al.   CELL

Visualizing Neuromodulation In Vivo: TANGO-Mapping of Dopamine Signaling Reveals Appetite Control of Sugar Sensing

(2012) Hidehiko K. Inagaki et al.   CELL

Leptin and insulin pathways in POMC and AgRP neurons that modulate energy balance and glucose homeostasis

(2012) Luis Varela et al.   EMBO REPORTS

High Identification Rates of Endogenous Neuropeptides from Mouse Brain

(2012) Xiaozhe Zhang et al.   JOURNAL OF PROTEOME RESEARCH

The animal and human neuroendocrinology of social cognition, motivation and behavior

(2012) Cade McCall et al.   NATURE NEUROSCIENCE

Homeodomain Protein Otp and Activity-Dependent Splicing Modulate Neuronal Adaptation to Stress

(2012) Liat Amir-Zilberstein et al.   NEURON

Peptide Neuromodulation in Invertebrate Model Systems

(2012) Paul H. Taghert et al.   NEURON

Neuropeptide Transmission in Brain Circuits

(2012) Anthony N. van den Pol   NEURON

Evoked Axonal Oxytocin Release in the Central Amygdala Attenuates Fear Response

(2012) H. Sophie Knobloch et al.   NEURON

Neuromodulation by Oxytocin and Vasopressin

(2012) Ron Stoop   NEURON

Neuromodulation of Neuronal Circuits: Back to the Future

(2012) Eve Marder   NEURON

Long-Range-Projecting GABAergic Neurons Modulate Inhibition in Hippocampus and Entorhinal Cortex

(2012) S. Melzer et al.   SCIENCE

Vasopressin/Oxytocin-Related Signaling Regulates Gustatory Associative Learning in C. elegans

(2012) I. Beets et al.   SCIENCE

Oxytocin/Vasopressin-Related Peptides Have an Ancient Role in Reproductive Behavior

(2012) J. L. Garrison et al.   SCIENCE

Whole-body gene expression pattern registration in Platynereis larvae

(2012) Albina Asadulina et al.   EvoDevo

More than two decades of research on insect neuropeptide GPCRs: an overview

(2012) Jelle Caers et al.   Frontiers in Endocrinology

G Protein–Coupled Receptor Deorphanizations

(2011) Olivier Civelli et al.   Annual Review of Pharmacology and Toxicology

Genetics of Sleep and Sleep Disorders

(2011) Amita Sehgal et al.   CELL

Presynaptic Facilitation by Neuropeptide Signaling Mediates Odor-Driven Food Search

(2011) Cory M. Root et al.   CELL

Olfactory networks: from sensation to perception

(2011) Sarah G Leinwand et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Presynaptic modulation of early olfactory processing in Drosophila

(2011) Jing W. Wang   Developmental Neurobiology

Vasopressin, oxytocin, and social odor recognition

(2011) Douglas W. Wacker et al.   HORMONES AND BEHAVIOR

Agonist-directed Interactions with Specific β-Arrestins Determine μ-Opioid Receptor Trafficking, Ubiquitination, and Dephosphorylation

(2011) Chad E. Groer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Resource of Cre Driver Lines for Genetic Targeting of GABAergic Neurons in Cerebral Cortex

(2011) Hiroki Taniguchi et al.   NEURON

Parasite neuropeptide biology: Seeding rational drug target selection?

(2011) Paul McVeigh et al.   International Journal for Parasitology-Drugs and Drug Resistance

Understanding wiring and volume transmission

(2010) Luigi F. Agnati et al.   BRAIN RESEARCH REVIEWS

A review of FMRFamide- and RFamide-like peptides in metazoa

(2010) Robert J. Walker et al.   INVERTEBRATE NEUROSCIENCE

Three Homologous Subunits Form a High Affinity Peptide-gated Ion Channel inHydra

(2010) Stefan Dürrnagel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Evolution of the Thyrotrophin-Releasing Hormone Precursor in Vertebrates: Insights From Comparative Genomics

(2010) M. Wallis   JOURNAL OF NEUROENDOCRINOLOGY

Neuropeptide feedback modifies odor-evoked dynamics in Caenorhabditis elegans olfactory neurons

(2010) Sreekanth H Chalasani et al.   NATURE NEUROSCIENCE

Unique biological function of cathepsin L in secretory vesicles for biosynthesis of neuropeptides

(2010) Lydiane Funkelstein et al.   NEUROPEPTIDES

Human kisspeptins activate neuropeptide FF2 receptor

(2010) Y. Lyubimov et al.   NEUROSCIENCE

Ghrelin Stimulation of Growth Hormone-Releasing Hormone Neurons Is Direct in the Arcuate Nucleus

(2010) Guillaume Osterstock et al.   PLoS One

Male Accessory Gland Protein Reduces Egg Laying in a Simultaneous Hermaphrodite

(2010) Joris M. Koene et al.   PLoS One

Activation of Neuropeptide FF Receptors by Kisspeptin Receptor Ligands

(2010) Shinya Oishi et al.   ACS Medicinal Chemistry Letters

Neuro-endocrine control of reproduction in hermaphroditic freshwater snails: mechanisms and evolution

(2010) Joris M. Joris M. Koene   Frontiers in Behavioral Neuroscience

Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways

(2009) Jeffrey J. Kovacs et al.   DEVELOPMENTAL CELL

Prolactin-releasing peptide effects in the rat brain are mediated through the Neuropeptide FF receptor

(2009) Li Ma et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

NGFFFamide and echinotocin: structurally unrelated myoactive neuropeptides derived from neurophysin-containing precursors in sea urchins

(2009) M. R. Elphick et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

An in vivo biosensor for neurotransmitter release and in situ receptor activity

(2009) Quoc-Thang Nguyen et al.   NATURE NEUROSCIENCE

PINP: A New Method of Tagging Neuronal Populations for Identification during In Vivo Electrophysiological Recording

(2009) Susana Q. Lima et al.   PLoS One

Presynaptic peptidergic modulation of olfactory receptor neurons in Drosophila

(2009) R. Ignell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sorting of neuropeptides and neuropeptide receptors into secretory pathways

(2009) Xu Zhang et al.   PROGRESS IN NEUROBIOLOGY

Proteases for Processing Proneuropeptides into Peptide Neurotransmitters and Hormones

(2008) Vivian Hook et al.   Annual Review of Pharmacology and Toxicology

Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addiction

(2008) M J Christie   BRITISH JOURNAL OF PHARMACOLOGY

Regulatory peptides in fruit fly midgut

(2008) Jan A. Veenstra et al.   CELL AND TISSUE RESEARCH

Prothyrotropin-releasing Hormone Targets Its Processing Products to Different Vesicles of the Secretory Pathway

(2008) Mario Perello et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Tissue-Specific Processing of Pro-Opiomelanocortin

(2008) A. B. Bicknell   JOURNAL OF NEUROENDOCRINOLOGY

FMRFamide neuropeptides and acetylcholine synergistically inhibit egg-laying by C. elegans

(2008) Niels Ringstad et al.   NATURE NEUROSCIENCE