Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway
出版年份 2018 全文链接
标题
Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway
作者
关键词
FL3, PHB, Urothelial carcinoma of the bladder, GADD45α, Cell cycle
出版物
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume 37, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-02-07
DOI
10.1186/s13046-018-0695-5
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Combinatorial therapy with adenoviral-mediated PTEN and a PI3K inhibitor suppresses malignant glioma cell growth in vitro and in vivo by regulating the PI3K/AKT signaling pathway
- (2017) Yang Nan et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- The Potential Value of the PI3K/Akt/mTOR Signaling Pathway for Assessing Prognosis in Cervical Cancer and as a Target for Therapy
- (2017) Afsane Bahrami et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Targeting prohibitins with chemical ligands inhibits KRAS-mediated lung tumours
- (2017) H Yurugi et al. ONCOGENE
- The PI3K/AKT Pathway as a Target for Cancer Treatment
- (2016) Ingrid A. Mayer et al. Annual Review of Medicine
- Cancer statistics in China, 2015
- (2016) Wanqing Chen et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Prohibitin in Adipose and Immune Functions
- (2016) Sudharsana R. Ande et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Identification of novel biomarkers associated with poor patient outcomes in invasive breast carcinoma
- (2016) Renata A. Canevari et al. TUMOR BIOLOGY
- Multifaceted role of prohibitin in cell survival and apoptosis
- (2015) Ya-Ting Peng et al. APOPTOSIS
- Unveiling the potential of prohibitin in cancer
- (2015) Sarah Koushyar et al. CANCER LETTERS
- Prohibitin (PHB) roles in granulosa cell physiology
- (2015) Indrajit Chowdhury et al. CELL AND TISSUE RESEARCH
- Estradiol Inhibits Th17 Cell Differentiation through Inhibition ofRORγTTranscription by Recruiting the ERα/REA Complex to Estrogen Response Elements of theRORγTPromoter
- (2015) Rong-Yi Chen et al. JOURNAL OF IMMUNOLOGY
- Prohibitin 1 gene delivery promotes functional recovery in rats with spinal cord injury
- (2015) L. Li et al. NEUROSCIENCE
- FL3, a Synthetic Flavagline and Ligand of Prohibitins, Protects Cardiomyocytes via STAT3 from Doxorubicin Toxicity
- (2015) Rehana Qureshi et al. PLoS One
- Cancer treatment and survivorship statistics, 2014
- (2014) Carol E. DeSantis et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Flavaglines target primitive leukemia cells and enhance anti-leukemia drug activity
- (2014) K P Callahan et al. LEUKEMIA
- Targeting the prohibitin scaffold-CRAF kinase interaction in RAS-ERK-driven pancreatic ductal adenocarcinoma
- (2014) Zhou Luan et al. Molecular Cancer
- Fucoidan Inhibits the Proliferation of Human Urinary Bladder Cancer T24 Cells by Blocking Cell Cycle Progression and Inducing Apoptosis
- (2014) Hye Park et al. MOLECULES
- A novel CyclinE/CyclinA-CDK Inhibitor targets p27Kip1 degradation, cell cycle progression and cell survival: Implications in cancer therapy
- (2013) Lu Dai et al. CANCER LETTERS
- Prohibitin Ligands in Cell Death and Survival: Mode of Action and Therapeutic Potential
- (2013) Frédéric Thuaud et al. CHEMISTRY & BIOLOGY
- Flavaglines: potent anticancer drugs that target prohibitins and the helicase eIF4A
- (2013) Christine Basmadjian et al. Future Medicinal Chemistry
- Prohibitins Role in Cellular Survival Through Ras-Raf-MEK-ERK Pathway
- (2013) Indrajit Chowdhury et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Signaling pathways of prohibitin and its role in diseases
- (2013) Tian-Biao Zhou et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- The Natural Anticancer Compounds Rocaglamides Inhibit the Raf-MEK-ERK Pathway by Targeting Prohibitin 1 and 2
- (2012) Gernot Polier et al. CHEMISTRY & BIOLOGY
- Flavaglines as Potent Anticancer and Cytoprotective Agents
- (2012) Nigel Ribeiro et al. JOURNAL OF MEDICINAL CHEMISTRY
- Current chemotherapeutic strategies against bladder cancer
- (2011) Yozo Mitsui et al. INTERNATIONAL UROLOGY AND NEPHROLOGY
- Prohibitin interacts with phosphatidylinositol 3,4,5-triphosphate (PIP3) and modulates insulin signaling
- (2009) Sudharsana R. Ande et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Synthetic Analogue of Rocaglaol Displays a Potent and Selective Cytotoxicity in Cancer Cells: Involvement of Apoptosis Inducing Factor and Caspase-12
- (2009) Frédéric Thuaud et al. JOURNAL OF MEDICINAL CHEMISTRY
- Prohibitin: a potential biomarker for tissue-based detection of gastric cancer
- (2008) Xiangdong Kang et al. JOURNAL OF GASTROENTEROLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now