FL3, a Synthetic Flavagline and Ligand of Prohibitins, Protects Cardiomyocytes via STAT3 from Doxorubicin Toxicity

P53 inhibition exacerbates late-stage anthracycline cardiotoxicity

(2014) Wuqiang Zhu et al.   CARDIOVASCULAR RESEARCH

miR-361-regulated prohibitin inhibits mitochondrial fission and apoptosis and protects heart from ischemia injury

(2014) K Wang et al.   CELL DEATH AND DIFFERENTIATION

Prohibitin 1 modulates mitochondrial function of Stat3

(2014) Jie Han et al.   CELLULAR SIGNALLING

The aberrant expression and localization of prohibitin during apoptosis of human cholangiocarcinoma Mz-ChA-1 cells

(2014) Wei Song et al.   FEBS LETTERS

Prevention of Anthracycline-Induced Cardiotoxicity

(2014) Pimprapa Vejpongsa et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The traditional Chinese medical compound Rocaglamide protects nonmalignant primary cells from DNA damage-induced toxicity by inhibition of p53 expression

(2014) M S Becker et al.   Cell Death & Disease

Prohibitin (PHB) inhibits apoptosis in rat granulosa cells (GCs) through the extracellular signal-regulated kinase 1/2 (ERK1/2) and the Bcl family of proteins

(2013) Indrajit Chowdhury et al.   APOPTOSIS

Prohibitin Ligands in Cell Death and Survival: Mode of Action and Therapeutic Potential

(2013) Frédéric Thuaud et al.   CHEMISTRY & BIOLOGY

Flavaglines: potent anticancer drugs that target prohibitins and the helicase eIF4A

(2013) Christine Basmadjian et al.   Future Medicinal Chemistry

Prohibitins Role in Cellular Survival Through Ras-Raf-MEK-ERK Pathway

(2013) Indrajit Chowdhury et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Interleukin 6 protects H2O2-induced cardiomyocytes injury through upregulation of prohibitin via STAT3 phosphorylation

(2012) Yuhua Jia et al.   CELL BIOCHEMISTRY AND FUNCTION

The Natural Anticancer Compounds Rocaglamides Inhibit the Raf-MEK-ERK Pathway by Targeting Prohibitin 1 and 2

(2012) Gernot Polier et al.   CHEMISTRY & BIOLOGY

Flavaglines as Potent Anticancer and Cytoprotective Agents

(2012) Nigel Ribeiro et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cardiac phosphoproteome reveals cell signaling events involved in doxorubicin cardiotoxicity

(2012) Séverine Gratia et al.   Journal of Proteomics

Mitochondrial–Nuclear Communication by Prohibitin Shuttling under Oxidative Stress

(2011) Srinivas R. Sripathi et al.   BIOCHEMISTRY

The role and therapeutic potential of prohibitin in disease

(2011) Arianne L. Theiss et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Erythropoietin Preserves the Endothelial Differentiation Capacity of Cardiac Progenitor Cells and Reduces Heart Failure during Anticancer Therapies

(2011) Melanie Hoch et al.   Cell Stem Cell

Prohibitin (PHB) acts as a potent survival factor against ceramide induced apoptosis in rat granulosa cells

(2011) Indrajit Chowdhury et al.   LIFE SCIENCES

Cytoprotection by the modulation of mitochondrial electron transport chain: The emerging role of mitochondrial STAT3

(2011) Karol Szczepanek et al.   MITOCHONDRION

Flavaglines Alleviate Doxorubicin Cardiotoxicity: Implication of Hsp27

(2011) Yohann Bernard et al.   PLoS One

Therapeutic Activation of Signal Transducer and Activator of Transcription 3 by Interleukin-11 Ameliorates Cardiac Fibrosis After Myocardial Infarction

(2010) Masanori Obana et al.   CIRCULATION

Prohibitin is expressed in pancreatic β-cells and protects against oxidative and proapoptotic effects of ethanol

(2009) Jong Han Lee et al.   FEBS Journal

Synthetic Analogue of Rocaglaol Displays a Potent and Selective Cytotoxicity in Cancer Cells: Involvement of Apoptosis Inducing Factor and Caspase-12

(2009) Frédéric Thuaud et al.   JOURNAL OF MEDICINAL CHEMISTRY

Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans

(2009) Marta Artal-Sanz et al.   NATURE

The PGE2-Stat3 interaction in doxorubicin-induced myocardial apoptosis

(2008) M. A. Frias et al.   CARDIOVASCULAR RESEARCH

Prohibitin protects against oxidative stress-induced cell injury in cultured neonatal cardiomyocyte

(2008) XiaoHua Liu et al.   CELL STRESS & CHAPERONES

β-Adrenergic Receptor Mediated Protection against Doxorubicin-Induced Apoptosis in Cardiomyocytes: The Impact of High Ambient Glucose

(2008) Naohiro Yano et al.   ENDOCRINOLOGY

The myocardial JAK/STAT pathway: From protection to failure

(2008) K BOENGLER et al.   PHARMACOLOGY & THERAPEUTICS

Suppression of Tumor Growth and Angiogenesis by a Specific Antagonist of the Cell-Surface Expressed Nucleolin

(2008) Damien Destouches et al.   PLoS One