Chemokines and Chemokine Receptors as Therapeutic Targets in Inflammatory Bowel Disease; Pitfalls and Promise
出版年份 2018 全文链接
标题
Chemokines and Chemokine Receptors as Therapeutic Targets in Inflammatory Bowel Disease; Pitfalls and Promise
作者
关键词
-
出版物
Journal of Crohns & Colitis
Volume -, Issue -, Pages -
出版商
Oxford University Press (OUP)
发表日期
2017-10-28
DOI
10.1093/ecco-jcc/jjx145
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Tissue Drug Concentrations of Anti-tumor Necrosis Factor Agents Are Associated with the Long-term Outcome of Patients with Crohnʼs Disease
- (2017) Takeo Yoshihara et al. INFLAMMATORY BOWEL DISEASES
- Eldelumab [anti-interferon-γ-inducible protein-10 antibody] Induction Therapy for Active Crohn’s Disease: a Randomised, Double-blind, Placebo-controlled Phase IIa Study
- (2017) William J. Sandborn et al. Journal of Crohns & Colitis
- A novel function of CXCL10 in mediating monocyte production of proinflammatory cytokines
- (2017) Qihong Zhao et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis
- (2017) Deepak A. Rao et al. NATURE
- A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15
- (2017) Borja Ocón et al. Frontiers in Immunology
- CitH3: a reliable blood biomarker for diagnosis and treatment of endotoxic shock
- (2017) Baihong Pan et al. Scientific Reports
- Impact of patient characteristics on the clinical efficacy of mongersen (GED-0301), an oral Smad7 antisense oligonucleotide, in active Crohn's disease
- (2016) G. Monteleone et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Chemokine and cytokine levels in inflammatory bowel disease patients
- (2016) Udai P. Singh et al. CYTOKINE
- Prevalence of Sclerosing Cholangitis Detected by Magnetic Resonance Cholangiography in Patients With Long-term Inflammatory Bowel Disease
- (2016) Aida Kapic Lunder et al. GASTROENTEROLOGY
- Leukocyte Trafficking to the Small Intestine and Colon
- (2016) Aida Habtezion et al. GASTROENTEROLOGY
- Intestinal CCL25 expression is increased in colitis and correlates with inflammatory activity
- (2016) Palak J. Trivedi et al. JOURNAL OF AUTOIMMUNITY
- Glucocorticoids Suppress CCR9-Mediated Chemotaxis, Calcium Flux, and Adhesion to MAdCAM-1 in Human T Cells
- (2016) Emily Wendt et al. JOURNAL OF IMMUNOLOGY
- Role of chemokine receptors and intestinal epithelial cells in the mucosal inflammation and tolerance
- (2016) Neeraja Kulkarni et al. JOURNAL OF LEUKOCYTE BIOLOGY
- A New Series of Orally Bioavailable Chemokine Receptor 9 (CCR9) Antagonists; Possible Agents for the Treatment of Inflammatory Bowel Disease
- (2016) S. Barret Kalindjian et al. JOURNAL OF MEDICINAL CHEMISTRY
- Randomised clinical trial: vercirnon, an oral CCR9 antagonist, vs. placebo as induction therapy in active Crohn's disease
- (2015) B. G. Feagan et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Targeting chemokines: Pathogens can, why can’t we?
- (2015) Amanda E.I. Proudfoot et al. CYTOKINE
- The association of tissue anti-TNF drug levels with serological and endoscopic disease activity in inflammatory bowel disease: the ATLAS study
- (2015) Andres J Yarur et al. GUT
- Eldelumab [Anti-IP-10] Induction Therapy for Ulcerative Colitis: A Randomised, Placebo-Controlled, Phase 2b Study
- (2015) William J. Sandborn et al. Journal of Crohns & Colitis
- CCR9 Antagonists in the Treatment of Ulcerative Colitis
- (2015) Pirow Bekker et al. MEDIATORS OF INFLAMMATION
- Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
- (2015) Jimmy Z Liu et al. NATURE GENETICS
- Mongersen, an Oral SMAD7 Antisense Oligonucleotide, and Crohn’s Disease
- (2015) Giovanni Monteleone et al. NEW ENGLAND JOURNAL OF MEDICINE
- The microbiota regulates type 2 immunity through ROR t+ T cells
- (2015) C. Ohnmacht et al. SCIENCE
- Expression of CCL20 and Its Corresponding Receptor CCR6 Is Enhanced in Active Inflammatory Bowel Disease, and TLR3 Mediates CCL20 Expression in Colonic Epithelial Cells
- (2015) Helene Kolstad Skovdahl et al. PLoS One
- The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer
- (2014) S T Ward et al. BRITISH JOURNAL OF CANCER
- T-Cell Trafficking and Anti-Adhesion Strategies in Inflammatory Bowel Disease: Current and Future Prospects
- (2014) Mahmoud H. Mosli et al. DRUGS
- CCL25/CCR9 Interactions Are Not Essential for Colitis Development but Are Required for Innate Immune Cell Protection from Chronic Experimental Murine Colitis
- (2014) Marc-André Wurbel et al. INFLAMMATORY BOWEL DISEASES
- Chemokine Cooperativity Is Caused by Competitive Glycosaminoglycan Binding
- (2014) F. Verkaar et al. JOURNAL OF IMMUNOLOGY
- Role and species-specific expression of colon T cell homing receptor GPR15 in colitis
- (2014) Linh P Nguyen et al. NATURE IMMUNOLOGY
- CCL25/CCR9 Interactions Regulate the Function of iNKT Cells in Oxazolone-Induced Colitis in Mice
- (2014) Siying Zhu et al. PLoS One
- The Role of CXCR3 in DSS-Induced Colitis
- (2014) Belal Chami et al. PLoS One
- Treatment of inflammatory bowel disease by chemokine receptor-targeted leukapheresis
- (2013) Michael Eberhardson et al. CLINICAL IMMUNOLOGY
- Anti-IP-10 antibody (BMS-936557) for ulcerative colitis: a phase II randomised study
- (2013) Lloyd Mayer et al. GUT
- Clinical disease activity, C-reactive protein normalisation and mucosal healing in Crohn's disease in the SONIC trial
- (2013) Laurent Peyrin-Biroulet et al. GUT
- Mucosal immunity in liver autoimmunity: A comprehensive review
- (2013) Palak J. Trivedi et al. JOURNAL OF AUTOIMMUNITY
- TLR1-induced chemokine production is critical for mucosal immunity against Yersinia enterocolitica
- (2013) Y Sugiura et al. Mucosal Immunology
- A Randomized Controlled Trial of the Efficacy and Safety of CCX282-B, an Orally-Administered Blocker of Chemokine Receptor CCR9, for Patients with Crohn’s Disease
- (2013) Satish Keshav et al. PLoS One
- Whole Genome Gene Expression Meta-Analysis of Inflammatory Bowel Disease Colon Mucosa Demonstrates Lack of Major Differences between Crohn's Disease and Ulcerative Colitis
- (2013) Atle van Beelen Granlund et al. PLoS One
- GPR15-Mediated Homing Controls Immune Homeostasis in the Large Intestine Mucosa
- (2013) S. V. Kim et al. SCIENCE
- A phase 1 open-label trial shows that smad7 antisense oligonucleotide (GED0301) does not increase the risk of small bowel strictures in Crohn's disease
- (2012) F. Zorzi et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Skin- and gut-homing molecules on human circulating γδ T cells and their dysregulation in inflammatory bowel disease
- (2012) E. R. Mann et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- CCL25 induces α4β7integrin-dependent migration of IL-17+γδ T lymphocytes during an allergic reaction
- (2012) Maria F. S. Costa et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Plasmacytoid Dendritic Cells Transport Peripheral Antigens to the Thymus to Promote Central Tolerance
- (2012) Husein Hadeiba et al. IMMUNITY
- CCR9+ plasmacytoid dendritic cells in the small intestine suppress development of intestinal inflammation in mice
- (2012) Shinta Mizuno et al. IMMUNOLOGY LETTERS
- Enhanced Expression of CXCL10 in Inflammatory Bowel Disease
- (2012) Ann E. Østvik et al. INFLAMMATORY BOWEL DISEASES
- Chemokine 25–induced signaling suppresses colon cancer invasion and metastasis
- (2012) Huanhuan Joyce Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Phase I Clinical Trial of Smad7 Knockdown Using Antisense Oligonucleotide in Patients With Active Crohn's Disease
- (2012) Giovanni Monteleone et al. MOLECULAR THERAPY
- HLA-DRhi and CCR9 Define a Pro-Inflammatory Monocyte Subset in IBD
- (2012) Ludvig Linton et al. Clinical and Translational Gastroenterology
- Smad7 Expression in T cells Prevents Colitis-Associated Cancer
- (2011) A. Rizzo et al. CANCER RESEARCH
- The Chemokine Receptor CCR9 Is Required for the T-Cell–Mediated Regulation of Chronic Ileitis in Mice
- (2011) Joshua D. Wermers et al. GASTROENTEROLOGY
- CCL17 Promotes Intestinal Inflammation in Mice and Counteracts Regulatory T Cell–Mediated Protection From Colitis
- (2011) Alexander F. Heiseke et al. GASTROENTEROLOGY
- Control of TH17 cells occurs in the small intestine
- (2011) Enric Esplugues et al. NATURE
- CCL25/CCR9 Interactions Regulate Large Intestinal Inflammation in a Murine Model of Acute Colitis
- (2011) Marc-Andre Wurbel et al. PLoS One
- Characterization of CCX282-B, an Orally Bioavailable Antagonist of the CCR9 Chemokine Receptor, for Treatment of Inflammatory Bowel Disease
- (2010) M. J. Walters et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Epithelial decision makers: in search of the 'epimmunome'
- (2010) Mahima Swamy et al. NATURE IMMUNOLOGY
- Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
- (2009) Ivaylo I. Ivanov et al. CELL
- CCL25 and CCL28 promote α4β7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow
- (2008) Alice Miles et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Role of β7 Integrin and the Chemokine/Chemokine Receptor Pair CCL25/CCR9 in Modeled TNF-Dependent Crohn's Disease
- (2008) Maria Apostolaki et al. GASTROENTEROLOGY
- Smad7 Controls Resistance of Colitogenic T Cells to Regulatory T Cell-Mediated Suppression
- (2008) Massimo C. Fantini et al. GASTROENTEROLOGY
- Lymphocyte homing and its role in the pathogenesis of IBD
- (2008) Bertus Eksteen et al. INFLAMMATORY BOWEL DISEASES
- CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease
- (2008) Husein Hadeiba et al. NATURE IMMUNOLOGY
- Maraviroc for Previously Treated Patients with R5 HIV-1 Infection
- (2008) Roy M. Gulick et al. NEW ENGLAND JOURNAL OF MEDICINE
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