The Autoimmune Lymphoproliferative Syndrome with Defective FAS or FAS-Ligand Functions

Somatic STAT5b gain-of-function mutations in early onset nonclonal eosinophilia, urticaria, dermatitis, and diarrhea

(2016) Chi A. Ma et al.   BLOOD

Disturbed B-lymphocyte selection in autoimmune lymphoproliferative syndrome

(2016) A. Janda et al.   BLOOD

CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice

(2016) Amanda Poissonnier et al.   IMMUNITY

Autoimmune lymphoproliferative syndrome due to somatic FAS mutation (ALPS-sFAS) combined with a germline caspase-10 (CASP10) variation

(2016) Ana Martínez-Feito et al.   IMMUNOBIOLOGY

Caspase-8 Deficiency Presenting as Late-Onset Multi-Organ Lymphocytic Infiltration with Granulomas in two Adult Siblings

(2015) Julie Niemela et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Defective anti-polysaccharide response and splenic marginal zone disorganization in ALPS patients

(2014) B. Neven et al.   BLOOD

Abnormally differentiated CD4+ or CD8+ T cells with phenotypic and genetic features of double negative T cells in human Fas deficiency

(2014) A. Rensing-Ehl et al.   BLOOD

Natural history of autoimmune lymphoproliferative syndrome associated withFASgene mutations

(2014) Susan Price et al.   BLOOD

A novel homozygous Fas ligand mutation leads to early protein truncation, abrogation of death receptor and reverse signaling and a severe form of the autoimmune lymphoproliferative syndrome

(2014) Schafiq Nabhani et al.   CLINICAL IMMUNOLOGY

Autoimmunity by haploinsufficiency

(2014) F. Rieux-Laucat et al.   SCIENCE

CD95L Cell Surface Cleavage Triggers a Prometastatic Signaling Pathway in Triple-Negative Breast Cancer

(2013) M. Malleter et al.   CANCER RESEARCH

The chains of death

(2013) Kolja Schleich et al.   CELL CYCLE

Investigation of common variable immunodeficiency patients and healthy individuals using autoimmune lymphoproliferative syndrome biomarkers

(2013) C.A. Roberts et al.   HUMAN IMMUNOLOGY

Diagnosis of autoimmune lymphoproliferative syndrome caused by FAS deficiency in adults

(2012) O. Lambotte et al.   HAEMATOLOGICA

Autoimmune lymphoproliferative syndrome caused by a homozygous null FAS ligand (FASLG) mutation

(2012) Aude Magerus-Chatinet et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A survey of 90 patients with autoimmune lymphoproliferative syndrome related to TNFRSF6 mutation

(2011) B. Neven et al.   BLOOD

How I treat autoimmune lymphoproliferative syndrome

(2011) V. K. Rao et al.   BLOOD

Regulation of CD95/Fas signaling at the DISC

(2011) I N Lavrik et al.   CELL DEATH AND DIFFERENTIATION

Familial Mediterranean fever and related periodic fever syndromes/autoinflammatory diseases

(2011) Sinisa Savic et al.   CURRENT OPINION IN RHEUMATOLOGY

Whole-Exome-Sequencing-Based Discovery of Human FADD Deficiency

(2010) Alexandre Bolze et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Somatic FAS mutations are common in patients with genetically undefined autoimmune lymphoproliferative syndrome

(2010) K. C. Dowdell et al.   BLOOD

Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop

(2010) J. B. Oliveira et al.   BLOOD

Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain

(2010) K. Luckerath et al.   BLOOD

Clinical and immunological overlap between autoimmune lymphoproliferative syndrome and common variable immunodeficiency

(2010) A. Rensing-Ehl et al.   CLINICAL IMMUNOLOGY

Using biomarkers to predict the presence of FAS mutations in patients with features of the autoimmune lymphoproliferative syndrome

(2010) Iusta Caminha et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Onset of autoimmune lymphoproliferative syndrome (ALPS) in humans as a consequence of genetic defect accumulation

(2010) Aude Magerus-Chatinet et al.   JOURNAL OF CLINICAL INVESTIGATION

FAS-L, IL-10, and double-negative CD4-CD8- TCR  / + T cells are reliable markers of autoimmune lymphoproliferative syndrome (ALPS) associated with FAS loss of function

(2009) A. Magerus-Chatinet et al.   BLOOD

FasL cross-linking inhibits activation of human peripheral T cells

(2009) M. Paulsen et al.   INTERNATIONAL IMMUNOLOGY

Yes and PI3K Bind CD95 to Signal Invasion of Glioblastoma

(2008) Susanne Kleber et al.   CANCER CELL