Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling

p53/microRNA-374b/AKT1 regulates colorectal cancer cell apoptosis in response to DNA damage

(2017) Hangjun Gong et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Curcumin inhibits urothelial tumor development by suppressing IGF2 and IGF2-mediated PI3K/AKT/mTOR signaling pathway

(2017) Binqiang Tian et al.   JOURNAL OF DRUG TARGETING

The Essential Medicinal Chemistry of Curcumin

(2017) Kathryn M. Nelson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Enhanced apoptosis, survivin down-regulation and assisted immunochemotherapy by curcumin loaded amphiphilic mixed micelles for subjugating endometrial cancer

(2017) Animesh Kumar et al.   Nanomedicine-Nanotechnology Biology and Medicine

miR-600 inhibits cell proliferation, migration and invasion by targeting p53 in mutant p53-expressing human colorectal cancer cell lines

(2017) Peili Zhang et al.   Oncology Letters

Curcumin induces G2/M cell cycle arrest and apoptosis of head and neck squamous cell carcinoma in vitro and in vivo through ATM/Chk2/p53-dependent pathway

(2017) An Hu et al.   Oncotarget

Early detection of gastric cancer using global, genome-wide and IRF4, ELMO1, CLIP4 and MSC DNA methylation in endoscopic biopsies

(2017) Francesca Pirini et al.   Oncotarget

Lectin-like oxidized low-density lipoprotein receptor-1 facilitates metastasis of gastric cancer through driving epithelial-mesenchymal transition and PI3K/Akt/GSK3β activation

(2017) Can Li et al.   Scientific Reports

P53 Regulation-Association Long Non-Coding RNA (LncRNA PRAL) Inhibits Cell Proliferation by Regulation of P53 in Human Lung Cancer

(2017) Pengxiao Su et al.   MEDICAL SCIENCE MONITOR

Gastric cancer

(2016) Eric Van Cutsem et al.   LANCET

Taxanes in the Treatment of Advanced Gastric Cancer

(2016) Byung Kang et al.   MOLECULES

Curcumin inhibits cell growth and induces cell apoptosis through upregulation of miR-33b in gastric cancer

(2016) Qianqian Sun et al.   TUMOR BIOLOGY

Curcumin sensitizes human gastric cancer cells to 5-fluorouracil through inhibition of the NFκB survival-signaling pathway

(2016) Yanting Kang et al.   OncoTargets and Therapy

Activation of PPARγ/P53 signaling is required for curcumin to induce hepatic stellate cell senescence

(2016) H Jin et al.   Cell Death & Disease

Prognostic Significance of p53 in Gastric Cancer: a Meta-Analysis

(2015) Mustafa Yildirim et al.   Asian Pacific Journal of Cancer Prevention

NEDD4 ubiquitin ligase is a putative oncogene in endometrial cancer that activates IGF-1R/PI3K/Akt signaling

(2015) Yuping Zhang et al.   GYNECOLOGIC ONCOLOGY

Fra-1 is upregulated in gastric cancer tissues and affects the PI3K/Akt and p53 signaling pathway in gastric cancer

(2015) JUNYU HE et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Safety and Efficacy of Buparlisib (BKM120) in Patients with PI3K Pathway-Activated Non-Small Cell Lung Cancer

(2015) Johan F. Vansteenkiste et al.   Journal of Thoracic Oncology

Selective killing of gastric cancer cells by a small molecule targeting ROS-mediated ER stress activation

(2015) Peng Zou et al.   MOLECULAR CARCINOGENESIS

Berberine and Curcumin Target Survivin and STAT3 in Gastric Cancer Cells and Synergize Actions of Standard Chemotherapeutic 5-Fluorouracil

(2015) Arvind Pandey et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Curcumin inhibits proliferation of gastric cancer cells by impairing ATP-sensitive potassium channel opening

(2015) Xiaohong Liu et al.   World Journal of Surgical Oncology

The PI3K/mTOR dual inhibitor P7170 demonstrates potent activity against endocrine-sensitive and endocrine-resistant ER+ breast cancer

(2014) Jennifer R. Bean et al.   BREAST CANCER RESEARCH AND TREATMENT

Curcumin inhibits the invasion of thyroid cancer cells via down-regulation of PI3K/Akt signaling pathway

(2014) XiaoBo Xu et al.   GENE

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Ras/ERK signaling pathway is involved in curcumin-induced cell cycle arrest and apoptosis in human gastric carcinoma AGS cells

(2014) Ai-Li Cao et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance

(2014) Oscar Tapia et al.   VIRCHOWS ARCHIV

Hepatocyte Nuclear Factor 6 Suppresses the Migration and Invasive Growth of Lung Cancer Cells through p53 and the Inhibition of Epithelial-Mesenchymal Transition

(2013) Xin-Wang Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Curcumin Induces the Differentiation of Myeloid-Derived Suppressor Cells and Inhibits Their Interaction with Cancer Cells and Related Tumor Growth

(2011) S. P. Tu et al.   Cancer Prevention Research

Phase IIa Clinical Trial of Curcumin for the Prevention of Colorectal Neoplasia

(2011) R. E. Carroll et al.   Cancer Prevention Research

Curcumin suppresses proliferation and invasion in human gastric cancer cells by down-regulation of PAK1 activity and cyclin D1 expression

(2010) Xin-Ze Cai et al.   CANCER BIOLOGY & THERAPY

The emerging mechanisms of isoform-specific PI3K signalling

(2010) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Capecitabine/cisplatin versus 5-fluorouracil/cisplatin as first-line therapy in patients with advanced gastric cancer: a randomised phase III noninferiority trial

(2009) Y.-K. Kang et al.   ANNALS OF ONCOLOGY

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

Curcumin as an Anti-Cancer Agent: Review of the Gap Between Basic and Clinical Applications

(2009) G. Bar-Sela et al.   CURRENT MEDICINAL CHEMISTRY

Diphenyl Difluoroketone: A Curcumin Derivative with Potent In vivo Anticancer Activity

(2008) D. Subramaniam et al.   CANCER RESEARCH

Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer

(2008) N. Dhillon et al.   CLINICAL CANCER RESEARCH