How cells sense their own shape – mechanisms to probe cell geometry and their implications in cellular organization and function

Planar cell polarity in development and disease

(2017) Mitchell T. Butler et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TRACMIT: An effective pipeline for tracking and analyzing cells on micropatterns through mitosis

(2017) Olivier Burri et al.   PLoS One

The Unsolved Problem of How Cells Sense Micron-Scale Curvature

(2017) Kevin S. Cannon et al.   TRENDS IN BIOCHEMICAL SCIENCES

Cell shape information is transduced through tension-independent mechanisms

(2017) Amit Ron et al.   Nature Communications

Dynactin binding to tyrosinated microtubules promotes centrosome centration in C. elegans by enhancing dynein-mediated organelle transport

(2017) Daniel J. Barbosa et al.   PLoS Genetics

Mechanical strain sensing implicated in cell shape recovery in Escherichia coli

(2017) Felix Wong et al.   Nature Microbiology

Relative Rates of Surface and Volume Synthesis Set Bacterial Cell Size

(2016) Leigh K. Harris et al.   CELL

How do cells know what shape they are?

(2016) Hui Kang et al.   CURRENT GENETICS

Pattern formation on membranes and its role in bacterial cell division

(2016) Simon Kretschmer et al.   CURRENT OPINION IN CELL BIOLOGY

Generic Theoretical Models to Predict Division Patterns of Cleaving Embryos

(2016) Anaëlle Pierre et al.   DEVELOPMENTAL CELL

Identification of clinically predictive metagenes that encode components of a network coupling cell shape to transcription by image-omics

(2016) Heba Z. Sailem et al.   GENOME RESEARCH

Micron-scale plasma membrane curvature is recognized by the septin cytoskeleton

(2016) Andrew A. Bridges et al.   JOURNAL OF CELL BIOLOGY

Shape–motion relationships of centering microtubule asters

(2016) Hirokazu Tanimoto et al.   JOURNAL OF CELL BIOLOGY

A theoretical model of cytokinesis implicates feedback between membrane curvature and cytoskeletal organization in asymmetric cytokinetic furrowing

(2016) Jonas F. Dorn et al.   MOLECULAR BIOLOGY OF THE CELL

Sensing a bud in the yeast morphogenesis checkpoint: a role for Elm1

(2016) Hui Kang et al.   MOLECULAR BIOLOGY OF THE CELL

Centrosome centering and decentering by microtubule network rearrangement

(2016) Gaëlle Letort et al.   MOLECULAR BIOLOGY OF THE CELL

Epithelial tricellular junctions act as interphase cell shape sensors to orient mitosis

(2016) Floris Bosveld et al.   NATURE

A force-generating machinery maintains the spindle at the cell center during mitosis

(2016) C. Garzon-Coral et al.   SCIENCE

Front–Rear Polarization by Mechanical Cues: From Single Cells to Tissues

(2016) Benoit Ladoux et al.   TRENDS IN CELL BIOLOGY

Microtubule organization is determined by the shape of epithelial cells

(2016) Juan Manuel Gomez et al.   Nature Communications

F-actin mechanics control spindle centring in the mouse zygote

(2016) Agathe Chaigne et al.   Nature Communications

Actin-Based Transport Adapts Polarity Domain Size to Local Cellular Curvature

(2015) Daria Bonazzi et al.   CURRENT BIOLOGY

Scaling, Selection, and Evolutionary Dynamics of the Mitotic Spindle

(2015) Reza Farhadifar et al.   CURRENT BIOLOGY

Septin Form and Function at the Cell Cortex

(2015) Andrew A. Bridges et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The contractile ring coordinates curvature-dependent septum assembly during fission yeast cytokinesis

(2015) Zhou Zhou et al.   MOLECULAR BIOLOGY OF THE CELL

Cell shape and the microenvironment regulate nuclear translocation of NF- B in breast epithelial and tumor cells

(2015) J. E. Sero et al.   Molecular Systems Biology

Active diffusion positions the nucleus in mouse oocytes

(2015) Maria Almonacid et al.   NATURE CELL BIOLOGY

Myosin II controls cellular branching morphogenesis and migration in three dimensions by minimizing cell-surface curvature

(2015) Hunter Elliott et al.   NATURE CELL BIOLOGY

Symmetry and scale orient Min protein patterns in shaped bacterial sculptures

(2015) Fabai Wu et al.   Nature Nanotechnology

Emergence of homeostatic epithelial packing and stress dissipation through divisions oriented along the long cell axis

(2015) Tom P. J. Wyatt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biological Scaling Problems and Solutions in Amphibians

(2015) Daniel L. Levy et al.   Cold Spring Harbor Perspectives in Biology

Cell-Size Control

(2015) Amanda A. Amodeo et al.   Cold Spring Harbor Perspectives in Biology

Probing Yeast Polarity with Acute, Reversible, Optogenetic Inhibition of Protein Function

(2015) Anna Payne-Tobin Jost et al.   ACS Synthetic Biology

How and why cells grow as rods

(2014) Fred Chang et al.   BMC BIOLOGY

The Interdependence of Membrane Shape and Cellular Signal Processing

(2014) Malte Schmick et al.   CELL

Interplay of Cell Shape and Division Orientation Promotes Robust Morphogenesis of Developing Epithelia

(2014) Fengzhu Xiong et al.   CELL

Symmetry Breaking in Spore Germination Relies on an Interplay between Polar Cap Stability and Spore Wall Mechanics

(2014) Daria Bonazzi et al.   DEVELOPMENTAL CELL

Exploring the Function of Cell Shape and Size during Mitosis

(2014) Clotilde Cadart et al.   DEVELOPMENTAL CELL

Effects of polymerization and nucleotide identity on the conformational dynamics of the bacterial actin homolog MreB

(2014) Alexandre Colavin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rod-like bacterial shape is maintained by feedback between cell curvature and cytoskeletal localization

(2014) T. S. Ursell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electrochemical Regulation of Budding Yeast Polarity

(2014) Armin Haupt et al.   PLOS BIOLOGY

Reconstitution of self-organizing protein gradients as spatial cues in cell-free systems

(2014) Katja Zieske et al.   eLife

Decoding Information in Cell Shape

(2013) Padmini Rangamani et al.   CELL

Mitotic Rounding Alters Cell Geometry to Ensure Efficient Bipolar Spindle Formation

(2013) Oscar M. Lancaster et al.   DEVELOPMENTAL CELL

Tension-oriented cell divisions limit anisotropic tissue tension in epithelial spreading during zebrafish epiboly

(2013) Pedro Campinho et al.   NATURE CELL BIOLOGY

Cargo Transport by Cytoplasmic Dynein Can Center Embryonic Centrosomes

(2013) Rafael A. Longoria et al.   PLoS One

Modulation of macrophage phenotype by cell shape

(2013) F. Y. McWhorter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Model of Fission Yeast Cell Shape Driven by Membrane-Bound Growth Factors and the Cytoskeleton

(2013) Tyler Drake et al.   PLoS Computational Biology

Mitotic spindle scaling during Xenopus development by kif2a and importin α

(2013) Jeremy D Wilbur et al.   eLife

Growth in width and FtsZ ring longitudinal positioning in a gammaproteobacterial symbiont

(2012) Nikolaus Leisch et al.   CURRENT BIOLOGY

Microfabricated devices for cell biology: all for one and one for all

(2012) Franziska Lautenschläger et al.   CURRENT OPINION IN CELL BIOLOGY

Growth, interaction, and positioning of microtubule asters in extremely large vertebrate embryo cells

(2012) Timothy Mitchison et al.   Cytoskeleton

The transition from meiotic to mitotic spindle assembly is gradual during early mammalian development

(2012) Aurélien Courtois et al.   JOURNAL OF CELL BIOLOGY

Reprogramming cell shape with laser nano-patterning

(2012) T. Vignaud et al.   JOURNAL OF CELL SCIENCE

Cylindrical cellular geometry ensures fidelity of division site placement in fission yeast

(2012) M. Mishra et al.   JOURNAL OF CELL SCIENCE

Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation

(2012) Tomomi Kiyomitsu et al.   NATURE CELL BIOLOGY

Geometry sensing by self-organized protein patterns

(2012) J. Schweizer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Centrosome in Cells and Organisms

(2012) M. Bornens   SCIENCE

Predicting division plane position and orientation

(2012) Nicolas Minc et al.   TRENDS IN CELL BIOLOGY

The mother-bud neck as a signaling platform for the coordination between spindle position and cytokinesis in budding yeast

(2011) Laura Merlini et al.   BIOLOGICAL CHEMISTRY

Control of the Mitotic Cleavage Plane by Local Epithelial Topology

(2011) William T. Gibson et al.   CELL

Influence of Cell Geometry on Division-Plane Positioning

(2011) Nicolas Minc et al.   CELL

Mechanisms for maintaining cell shape in rod-shaped Gram-negative bacteria

(2011) Leon Furchtgott et al.   MOLECULAR MICROBIOLOGY

External forces control mitotic spindle positioning

(2011) Jenny Fink et al.   NATURE CELL BIOLOGY

De Novo Growth Zone Formation from Fission Yeast Spheroplasts

(2011) Felice D. Kelly et al.   PLoS One

Neocortical Interneurons: From Diversity, Strength

(2010) Christopher I. Moore et al.   CELL

How does a millimeter-sized cell find its center?

(2010) Martin Wühr et al.   CELL CYCLE

A Model for Cleavage Plane Determination in Early Amphibian and Fish Embryos

(2010) Martin Wühr et al.   CURRENT BIOLOGY

Finding the Cell Center by a Balance of Dynein and Myosin Pulling and Microtubule Pushing: A Computational Study

(2010) Jie Zhu et al.   MOLECULAR BIOLOGY OF THE CELL

Intracellular organelles mediate cytoplasmic pulling force for centrosome centration in the Caenorhabditis elegans early embryo

(2010) K. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Geometric cues for directing the differentiation of mesenchymal stem cells

(2010) K. A. Kilian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Lineage Reconstruction of Early Zebrafish Embryos Using Label-Free Nonlinear Microscopy

(2010) N. Olivier et al.   SCIENCE

A Septin Diffusion Barrier at the Base of the Primary Cilium Maintains Ciliary Membrane Protein Distribution

(2010) Q. Hu et al.   SCIENCE

A Polarised Population of Dynamic Microtubules Mediates Homeostatic Length Control in Animal Cells

(2010) Remigio Picone et al.   PLOS BIOLOGY

Local Cortical Tension by Myosin II Guides 3D Endothelial Cell Branching

(2009) Robert S. Fischer et al.   CURRENT BIOLOGY

Effects of Confinement on the Self-Organization of Microtubules and Motors

(2009) M. Pinot et al.   CURRENT BIOLOGY

Establishing New Sites of Polarization by Microtubules

(2009) Nicolas Minc et al.   CURRENT BIOLOGY

Positioning cytokinesis

(2009) S. Oliferenko et al.   GENES & DEVELOPMENT

Shaping Fission Yeast with Microtubules

(2009) F. Chang et al.   Cold Spring Harbor Perspectives in Biology

Physical Mechanisms Redirecting Cell Polarity and Cell Shape in Fission Yeast

(2008) Courtney R. Terenna et al.   CURRENT BIOLOGY

Get round and stiff for mitosis

(2008) Manuel Théry et al.   HFSP Journal

Self-organization in cell biology: a brief history

(2008) Eric Karsenti   NATURE REVIEWS MOLECULAR CELL BIOLOGY