C6orf106 is a novel inhibitor of the interferon-regulatory factor 3–dependent innate antiviral response

Lipid droplet density alters the early innate immune response to viral infection

(2018) Ebony A. Monson et al.   PLoS One

Cellular FLIP long isoform (cFLIPL)–IKKα interactions inhibit IRF7 activation, representing a new cellular strategy to inhibit IFNα expression

(2017) Lauren T. Gates-Tanzer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

cFLIPLInterrupts IRF3–CBP–DNA Interactions To Inhibit IRF3-Driven Transcription

(2016) Lauren T. Gates et al.   JOURNAL OF IMMUNOLOGY

Varicella-Zoster Virus Activates CREB, and Inhibition of the pCREB-p300/CBP Interaction Inhibits Viral ReplicationIn Vitroand Skin PathogenesisIn Vivo

(2016) Sylvie François et al.   JOURNAL OF VIROLOGY

Fas-Associated Factor 1 Negatively Regulates the Antiviral Immune Response by Inhibiting Translocation of Interferon Regulatory Factor 3 to the Nucleus

(2016) Soonhwa Song et al.   MOLECULAR AND CELLULAR BIOLOGY

Genome-wide siRNA Screening at Biosafety Level 4 Reveals a Crucial Role for Fibrillarin in Henipavirus Infection

(2016) Celine Deffrasnes et al.   PLoS Pathogens

C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn

(2015) Xiupeng Zhang et al.   TUMOR BIOLOGY

A novel biomarker C6orf106 promotes the malignant progression of breast cancer

(2015) Guiyang Jiang et al.   TUMOR BIOLOGY

The immunomodulating V and W proteins of Nipah virus determine disease course

(2015) Benjamin A. Satterfield et al.   Nature Communications

TRIM26 Negatively Regulates Interferon-β Production and Antiviral Response through Polyubiquitination and Degradation of Nuclear IRF3

(2015) Peng Wang et al.   PLoS Pathogens

Phosphorylation of p300 increases its protein degradation to enhance the lung cancer progression

(2014) Shao-An Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection

(2014) Roberto Ferrari et al.   Cell Host & Microbe

USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase

(2014) Yihui Fan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TRIF and IRF-3 Binding to the TNF Promoter Results in Macrophage TNF Dysregulation and Steatosis Induced by Chronic Ethanol

(2014) X.-J. Zhao et al.   JOURNAL OF IMMUNOLOGY

cAMP signalling decreases p300 protein levels by promoting its ubiquitin/proteasome dependent degradation via Epac and p38 MAPK in lung cancer cells

(2013) Min-Jae Jeong et al.   FEBS LETTERS

FoxO1 Negatively Regulates Cellular Antiviral Response by Promoting Degradation of IRF3

(2013) Cao-Qi Lei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of T-cell function by type I interferon

(2012) David F Tough   IMMUNOLOGY AND CELL BIOLOGY

A Novel Nuclear Trafficking Module Regulates the Nucleocytoplasmic Localization of the Rabies Virus Interferon Antagonist, P Protein

(2012) Sibil Oksayan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Visualisation of direct interaction of MDA5 and the dsRNA replicative intermediate form of positive strand RNA viruses

(2012) K. Triantafilou et al.   JOURNAL OF CELL SCIENCE

Cedar Virus: A Novel Henipavirus Isolated from Australian Bats

(2012) Glenn A. Marsh et al.   PLoS Pathogens

Antiviral responses induced by the TLR3 pathway

(2011) Misako Matsumoto et al.   REVIEWS IN MEDICAL VIROLOGY

Interferon-stimulated genes and their antiviral effector functions

(2011) John W Schoggins et al.   Current Opinion in Virology

Hip2 interacts with cyclin B1 and promotes its degradation through the ubiquitin proteasome pathway

(2010) Yoonhee Bae et al.   FEBS LETTERS

The Ubiquitin E3 Ligase RAUL Negatively Regulates Type I Interferon through Ubiquitination of the Transcription Factors IRF7 and IRF3

(2010) Yanxing Yu et al.   IMMUNITY

Negative Role of RIG-I Serine 8 Phosphorylation in the Regulation of Interferon-β Production

(2010) Estanislao Nistal-Villán et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3

(2008) Min Zhang et al.   CELL RESEARCH

poly(I:C) and LPS induce distinct IRF3 and NF-κB signaling during type-I IFN and TNF responses in human macrophages

(2008) Thornik Reimer et al.   JOURNAL OF LEUKOCYTE BIOLOGY