Reassignment of the human aldehyde dehydrogenase ALDH8A1 (ALDH12) to the kynurenine pathway in tryptophan catabolism

α-Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of De Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis

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Kynurenines: Tryptophan’s metabolites in exercise, inflammation, and mental health

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A Pitcher-and-Catcher Mechanism Drives Endogenous Substrate Isomerization by a Dehydrogenase in Kynurenine Metabolism

(2016) Yu Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

What is the tryptophan kynurenine pathway and why is it important to neurotherapeutics?

(2015) Ian Davis et al.   Expert Review of Neurotherapeutics

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

Crystallographic and spectroscopic snapshots reveal a dehydrogenase in action

(2015) Lu Huo et al.   Nature Communications

What is the tryptophan kynurenine pathway and why is it important to neurotherapeutics?

(2015) Ian Davis et al.   Expert Review of Neurotherapeutics

Human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD): A structural and mechanistic unveiling

(2014) Lu Huo et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structure and mechanism of kynureninase

(2013) Robert S. Phillips   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Structural Basis for a Cofactor-dependent Oxidation Protection and Catalysis of Cyanobacterial Succinic Semialdehyde Dehydrogenase

(2013) Jinseo Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Power of Two

(2013) Lu Huo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for a Dual Role of an Active Site Histidine in α-Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase

(2012) Lu Huo et al.   BIOCHEMISTRY

Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

(2012) L. Pilotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Formyl Kynurenine Formamidase and Kynurenine Aminotransferase fromSaccharomyces cerevisiaeUsing Crystallographic, Bioinformatic and Biochemical Evidence‡

(2008) Mark Wogulis et al.   BIOCHEMISTRY

NAD Biosynthesis Evolution in Bacteria: Lateral Gene Transfer of Kynurenine Pathway in Xanthomonadales and Flavobacteriales

(2008) W. C. Lima et al.   MOLECULAR BIOLOGY AND EVOLUTION

mMass data miner: an open source alternative for mass spectrometric data analysis

(2008) Martin Strohalm et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY