Dysregulation and Dislocation of SFPQ Disturbed DNA Organization in Alzheimer’s Disease and Frontotemporal Dementia

Opening up the DNA methylome of dementia

(2017) R Delgado-Morales et al.   MOLECULAR PSYCHIATRY

Non-nuclear Pool of Splicing Factor SFPQ Regulates Axonal Transcripts Required for Normal Motor Development

(2017) Swapna Thomas-Jinu et al.   NEURON

Altered Tau Isoform Ratio Caused by Loss of FUS and SFPQ Function Leads to FTLD-like Phenotypes

(2017) Shinsuke Ishigaki et al.   Cell Reports

Tau physiology and pathomechanisms in frontotemporal lobar degeneration

(2016) Liviu-Gabriel Bodea et al.   JOURNAL OF NEUROCHEMISTRY

SFPQ•NONO and XLF function separately and together to promote DNA double-strand break repair via canonical nonhomologous end joining

(2016) Lahcen Jaafar et al.   NUCLEIC ACIDS RESEARCH

The DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffold

(2016) Gavin J. Knott et al.   NUCLEIC ACIDS RESEARCH

PSF: nuclear busy-body or nuclear facilitator?

(2015) Christopher A. Yarosh et al.   Wiley Interdisciplinary Reviews-RNA

Structure and Function of Centromeric and Pericentromeric Heterochromatin in Arabidopsis thaliana

(2015) Lauriane Simon et al.   Frontiers in Plant Science

DNA methylation map of mouse and human brain identifies target genes in Alzheimer’s disease

(2013) Jose V. Sanchez-Mut et al.   BRAIN

Remodelling of a polypyrimidine tract-binding protein complex during apoptosis activates cellular IRESs

(2013) H A King et al.   CELL DEATH AND DIFFERENTIATION

The RNA/DNA-binding protein PSF relocates to cell membrane and contributes cells' sensitivity to antitumor drug, doxorubicin

(2013) Simei Ren et al.   CYTOMETRY PART A

Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β

(2013) Elsa Suberbielle et al.   NATURE NEUROSCIENCE

What Renders TAU Toxic

(2013) Jürgen Götz et al.   Frontiers in Neurology

Tau-Mediated Nuclear Depletion and Cytoplasmic Accumulation of SFPQ in Alzheimer's and Pick's Disease

(2012) Yazi Ke et al.   PLoS One

Annexin A2 and PSF proteins interact with p53 IRES and regulate translation of p53 mRNA

(2012) Arandkar Sharathchandra et al.   RNA Biology

PSF Suppresses Tau Exon 10 Inclusion by Interacting with a Stem-Loop Structure Downstream of Exon 10

(2011) Payal Ray et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Phosphorylation-Dependent Regulation of PSF by GSK3 Controls CD45 Alternative Splicing

(2010) Florian Heyd et al.   MOLECULAR CELL

The splicing-factor related protein SFPQ/PSF interacts with RAD51D and is necessary for homology-directed repair and sister chromatid cohesion

(2010) Changanamkandath Rajesh et al.   NUCLEIC ACIDS RESEARCH

Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution

(2009) Irina Solovei et al.   CELL

BRK phosphorylates PSF promoting its cytoplasmic localization and cell cycle arrest

(2009) Kiven E. Lukong et al.   CELLULAR SIGNALLING

Human PSF binds to RAD51 and modulates its homologous-pairing and strand-exchange activities

(2009) Y. Morozumi et al.   NUCLEIC ACIDS RESEARCH