SFPQ•NONO and XLF function separately and together to promote DNA double-strand break repair via canonical nonhomologous end joining

Structure, Dynamics, and Interaction of p54nrb/NonO RRM1 with 5′ Splice Site RNA Sequence

(2016) Jean-Baptiste Duvignaud et al.   BIOCHEMISTRY

Two-Stage Synapsis of DNA Ends during Non-homologous End Joining

(2016) Thomas G.W. Graham et al.   MOLECULAR CELL

The DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffold

(2016) Gavin J. Knott et al.   NUCLEIC ACIDS RESEARCH

Characterization of DNA binding and pairing activities associated with the native SFPQ·NONO DNA repair protein complex

(2015) Durga Udayakumar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

XRCC4/XLF Interaction Is Variably Required for DNA Repair and Is Not Required for Ligase IV Stimulation

(2015) Sunetra Roy et al.   MOLECULAR AND CELLULAR BIOLOGY

Mutations in NONO lead to syndromic intellectual disability and inhibitory synaptic defects

(2015) Dennis Mircsof et al.   NATURE NEUROSCIENCE

The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation

(2015) Mihwa Lee et al.   NUCLEIC ACIDS RESEARCH

Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair

(2015) Dylan A. Reid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caenorhabditis elegansNONO-1: Insights into DBHS protein structure, architecture, and function

(2015) Gavin J. Knott et al.   PROTEIN SCIENCE

PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

(2015) T. Ochi et al.   SCIENCE

Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway

(2015) Mengtan Xing et al.   Nature Communications

PSF: nuclear busy-body or nuclear facilitator?

(2015) Christopher A. Yarosh et al.   Wiley Interdisciplinary Reviews-RNA

Looping Back to Leap Forward: Transcription Enters a New Era

(2014) Michael Levine et al.   CELL

Structural insights into NHEJ: Building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time

(2014) Gareth J. Williams et al.   DNA REPAIR

Nonhomologous end joining: A good solution for bad ends

(2014) Crystal A. Waters et al.   DNA REPAIR

The spatial organization of non-homologous end joining: From bridging to end joining

(2014) Takashi Ochi et al.   DNA REPAIR

A role for XLF in DNA repair and recombination in human somatic cells

(2014) Farjana Jahan Fattah et al.   DNA REPAIR

Effects of a Novel Long Noncoding RNA, lncUSMycN, on N-Myc Expression and Neuroblastoma Progression

(2014) Pei Y. Liu et al.   JNCI-Journal of the National Cancer Institute

Double-strand break repair deficiency in NONO knockout murine embryonic fibroblasts and compensation by spontaneous upregulation of the PSPC1 paralog

(2014) Shuyi Li et al.   NUCLEIC ACIDS RESEARCH

Type II restriction endonucleases—a historical perspective and more

(2014) Alfred Pingoud et al.   NUCLEIC ACIDS RESEARCH

Cooperative Assembly of a Protein-DNA Filament for Nonhomologous End Joining

(2013) Chun J. Tsai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A noncatalytic function of the ligation complex during nonhomologous end joining

(2013) Jessica Cottarel et al.   JOURNAL OF CELL BIOLOGY

PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks

(2012) Jana Krietsch et al.   NUCLEIC ACIDS RESEARCH

A human XRCC4–XLF complex bridges DNA

(2012) Sara N. Andres et al.   NUCLEIC ACIDS RESEARCH

Structure of the heterodimer of human NONO and paraspeckle protein component 1 and analysis of its role in subnuclear body formation

(2012) D. M. Passon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p54nrb is a new regulator of progression of malignant melanoma

(2011) S. Schiffner et al.   CARCINOGENESIS

Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response

(2011) Maayan Salton et al.   CELL CYCLE

XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair

(2011) Michal Hammel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human PSF concentrates DNA and stimulates duplex capture in DMC1-mediated homologous pairing

(2011) Yuichi Morozumi et al.   NUCLEIC ACIDS RESEARCH

Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining

(2011) V. Ropars et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequences in PSF/SFPQ mediate radioresistance and recruitment of PSF/SFPQ-containing complexes to DNA damage sites in human cells

(2010) Kyungsoo Ha et al.   DNA REPAIR

Use of a microscope stage-mounted Nickel-63 microirradiator for real-time observation of the DNA double-strand break response

(2010) Zhen Cao et al.   NUCLEIC ACIDS RESEARCH

The splicing-factor related protein SFPQ/PSF interacts with RAD51D and is necessary for homology-directed repair and sister chromatid cohesion

(2010) Changanamkandath Rajesh et al.   NUCLEIC ACIDS RESEARCH

Ku70 Corrupts DNA Repair in the Absence of the Fanconi Anemia Pathway

(2010) P. Pace et al.   SCIENCE

XLF Regulates Filament Architecture of the XRCC4·Ligase IV Complex

(2010) Michal Hammel et al.   STRUCTURE

Ku and DNA-dependent Protein Kinase Dynamic Conformations and Assembly Regulate DNA Binding and the Initial Non-homologous End Joining Complex

(2009) Michal Hammel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human PSF binds to RAD51 and modulates its homologous-pairing and strand-exchange activities

(2009) Y. Morozumi et al.   NUCLEIC ACIDS RESEARCH

Involvement of p54(nrb), a PSF partner protein, in DNA double-strand break repair and radioresistance

(2009) Shuyi Li et al.   NUCLEIC ACIDS RESEARCH

Cellular responses to DNA double-strand breaks after low-dose γ-irradiation

(2009) Aroumougame Asaithamby et al.   NUCLEIC ACIDS RESEARCH