Contemporary Considerations for Constructing a Genetic Risk Score: An Empirical Approach

Incremental value of a genetic risk score for the prediction of new vascular events in patients with clinically manifest vascular disease

(2015) Maaike Weijmans et al.   ATHEROSCLEROSIS

Detection and replication of epistasis influencing transcription in humans

(2014) Gibran Hemani et al.   NATURE

Simple, standardized incorporation of genetic risk into non-genetic risk prediction tools for complex traits: coronary heart disease as an example

(2014) Benjamin A. Goldstein et al.   Frontiers in Genetics

Strategies for Developing Prediction Models From Genome-Wide Association Studies

(2013) Jincao Wu et al.   GENETIC EPIDEMIOLOGY

Integration of genomics into the electronic health record: mapping terra incognita

(2013) Joseph L. Kannry et al.   GENETICS IN MEDICINE

Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies

(2013) Nilanjan Chatterjee et al.   NATURE GENETICS

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Testing for improvement in prediction model performance

(2013) Margaret Sullivan Pepe et al.   STATISTICS IN MEDICINE

Five Years of GWAS Discovery

(2012) Peter M. Visscher et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Genetic Risk Score Is Associated With Incident Cardiovascular Disease and Coronary Artery Calcium

(2012) George Thanassoulis et al.   Circulation-Cardiovascular Genetics

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

(2012) Eli A Stahl et al.   NATURE GENETICS

Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

(2012) Bryan Howie et al.   NATURE GENETICS

Misuse of DeLong test to compare AUCs for nested models

(2012) Olga V. Demler et al.   STATISTICS IN MEDICINE

Recent methods for polygenic analysis of genome-wide data implicate an important effect of common variants on cardiovascular disease risk

(2011) Matthew A Simonson et al.   BMC Medical Genetics

Genetic risk prediction in complex disease

(2011) Luke Jostins et al.   HUMAN MOLECULAR GENETICS

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

(2011) Heribert Schunkert et al.   NATURE GENETICS

Using multiple genetic variants as instrumental variables for modifiable risk factors

(2011) Tom M Palmer et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Synthetic Associations Created by Rare Variants Do Not Explain Most GWAS Results

(2011) Naomi R. Wray et al.   PLOS BIOLOGY

An application of Random Forests to a genome-wide association dataset: Methodological considerations & new findings

(2010) Benjamin A Goldstein et al.   BMC GENETICS

Genetic Cardiovascular Risk Prediction

(2010) George Thanassoulis et al.   CIRCULATION

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

(2010) Yun Li et al.   GENETIC EPIDEMIOLOGY

Genetic Scoring Analysis: a way forward in Genome Wide Association Studies?

(2009) Najaf Amin et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score

(2009) Philip L De Jager et al.   LANCET NEUROLOGY

Data and Theory Point to Mainly Additive Genetic Variance for Complex Traits

(2008) William G. Hill et al.   PLoS Genetics