Simple, standardized incorporation of genetic risk into non-genetic risk prediction tools for complex traits: coronary heart disease as an example

Assessing calibration of prognostic risk scores

(2016) Cynthia S Crowson et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Multilocus Genetic Risk Scores for Coronary Heart Disease Prediction

(2013) Andrea Ganna et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk

(2013) David C. Goff et al.   CIRCULATION

Comment on the Reports of Over-estimation of ASCVD Risk Using the 2013 AHA/ACC Risk Equation

(2013) Paul Muntner et al.   CIRCULATION

Response to Comment on the Reports of Over-estimation of ASCVD Risk Using the 2013 AHA/ACC Risk Equation

(2013) Nancy R. Cook et al.   CIRCULATION

Net Reclassification Indices for Evaluating Risk Prediction Instruments

(2013) Kathleen F. Kerr et al.   EPIDEMIOLOGY

Clinical genomics in the world of the electronic health record

(2013) Keith Marsolo et al.   GENETICS IN MEDICINE

Practical challenges in integrating genomic data into the electronic health record

(2013) Abel N. Kho et al.   GENETICS IN MEDICINE

The Electronic Medical Records and Genomics (eMERGE) Network: past, present and future

(2013) Omri Gottesman et al.   GENETICS IN MEDICINE

More Than a Billion People Taking Statins?

(2013) John P. A. Ioannidis   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies

(2012) Ariel Brautbar et al.   ATHEROSCLEROSIS

Randomized Trial of Personal Genomics for Preventive Cardiology

(2012) Joshua W. Knowles et al.   Circulation-Cardiovascular Genetics

Personalized Genetic Risk Counseling to Motivate Diabetes Prevention: A randomized trial

(2012) R. W. Grant et al.   DIABETES CARE

Preferences for opt-in and opt-out enrollment and consent models in biobank research: a national survey of Veterans Administration patients

(2012) David Kaufman et al.   GENETICS IN MEDICINE

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

(2012) Bryan Howie et al.   NATURE GENETICS

Large-scale association analysis identifies new risk loci for coronary artery disease

(2012) Panos Deloukas et al.   NATURE GENETICS

Genetic Markers Enhance Coronary Risk Prediction in Men: The MORGAM Prospective Cohorts

(2012) Maria F. Hughes et al.   PLoS One

Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm

(2011) Thomas J. Hoffmann et al.   GENOMICS

Next generation genome-wide association tool: Design and coverage of a high-throughput European-optimized SNP array

(2011) Thomas J. Hoffmann et al.   GENOMICS

What Makes a Good Predictor?

(2010) John P. A. Ioannidis et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score

(2009) Philip L De Jager et al.   LANCET NEUROLOGY