Role of Microenvironment in Glioma Invasion: What We Learned from In Vitro Models

Endothelium-induced three-dimensional invasion of heterogeneous glioma initiating cells in a microfluidic coculture platform

(2017) Yuta Chonan et al.   Integrative Biology

Tissue-engineered 3D microvessel and capillary network models for the study of vascular phenomena

(2017) Max I. Bogorad et al.   MICROCIRCULATION

Recent advances in the use of PI3K inhibitors for glioblastoma multiforme: current preclinical and clinical development

(2017) Hua-fu Zhao et al.   Molecular Cancer

An NF-κB signature predicts low-grade glioma prognosis: a precision medicine approach based on patient-derived stem cells

(2017) Tamara Ius et al.   NEURO-ONCOLOGY

Tumor microenvironment in treatment of glioma

(2017) Guijie Li et al.   Open Medicine

Molecular and Microenvironmental Determinants of Glioma Stem-Like Cell Survival and Invasion

(2017) Alison Roos et al.   Frontiers in Oncology

Guidelines for the selection of functional assays to evaluate the hallmarks of cancer

(2016) Otília Menyhárt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Acidosis Acts through HSP90 in a PHD/VHL-Independent Manner to Promote HIF Function and Stem Cell Maintenance in Glioma

(2016) Alina Filatova et al.   CANCER RESEARCH

A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo

(2016) Christopher G. Hubert et al.   CANCER RESEARCH

Interstitial flow differentially increases patient-derived glioblastoma stem cell invasion via CXCR4, CXCL12, and CD44-mediated mechanisms

(2016) Kathryn M. Kingsmore et al.   Integrative Biology

Effect of matrix metalloproteinase-mediated matrix degradation on glioblastoma cell behavior in 3D PEG-based hydrogels

(2016) Christine Wang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Glioma Stem Cells but Not Bulk Glioma Cells Upregulate IL-6 Secretion in Microglia/Brain Macrophages via Toll-like Receptor 4 Signaling

(2016) Omar Dildar a Dzaye et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

N-cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells

(2016) Brian D. Cosgrove et al.   NATURE MATERIALS

The angiogenic switch leads to a metabolic shift in human glioblastoma

(2016) Krishna M. Talasila et al.   NEURO-ONCOLOGY

Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer

(2016) Caroline Wigerup et al.   PHARMACOLOGY & THERAPEUTICS

Glioma cell invasion is significantly enhanced in composite hydrogel matrices composed of chondroitin 4- and 4,6-sulfated glycosaminoglycans

(2016) Meghan T. Logun et al.   Journal of Materials Chemistry B

Glioblastoma Stem-Like Cells: Characteristics, Microenvironment, and Therapy

(2016) Yang Yi et al.   Frontiers in Pharmacology

Coculture Assays to Study Macrophage and Microglia Stimulation of Glioblastoma Invasion

(2016) Salvatore Coniglio et al.   Jove-Journal of Visualized Experiments

Modeling tumor microenvironments using custom-designed biomaterial scaffolds

(2016) Zen Liu et al.   Current Opinion in Chemical Engineering

Differential response of patient-derived primary glioblastoma cells to environmental stiffness

(2016) Thomas James Grundy et al.   Scientific Reports

Fluvoxamine, an anti-depressant, inhibits human glioblastoma invasion by disrupting actin polymerization

(2016) Keiichiro Hayashi et al.   Scientific Reports

Strategies of Mesenchymal Invasion of Patient-derived Brain Tumors: Microenvironmental Adaptation

(2016) Junghwa Cha et al.   Scientific Reports

Hypoxia-mediated cancer stem cells in pseudopalisades with activation of hypoxia-inducible factor-1α/Akt axis in glioblastoma

(2015) Madoka Inukai et al.   HUMAN PATHOLOGY

Review: in vitro microvessel models

(2015) Max I. Bogorad et al.   LAB ON A CHIP

An artificial blood vessel implanted three-dimensional microsystem for modeling transvascular migration of tumor cells

(2015) Xue-Ying Wang et al.   LAB ON A CHIP

Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

(2015) Wenchao Zhou et al.   NATURE CELL BIOLOGY

ADAM-9 is a novel mediator of tenascin-C-stimulated invasiveness of brain tumor–initiating cells

(2015) Susobhan Sarkar et al.   NEURO-ONCOLOGY

Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 Pathway

(2015) Anwar Hossain et al.   STEM CELLS

The role of astrocytes in the progression of brain cancer: complicating the picture of the tumor microenvironment

(2015) Amanda L. Placone et al.   TUMOR BIOLOGY

A synthetic hydrogel for the high-throughput study of cell–ECM interactions

(2015) Andrew D. Rape et al.   Nature Communications

Role of tenascins in the ECM of gliomas

(2015) Nicole Brösicke et al.   Cell Adhesion & Migration

Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis

(2015) Xi Feng et al.   Oncotarget

Coculture with astrocytes reduces the radiosensitivity of glioblastoma stem-like cells and identifies additional targets for radiosensitization

(2015) Barbara H. Rath et al.   Cancer Medicine

Spherical Cancer Models in Tumor Biology

(2015) Louis-Bastien Weiswald et al.   NEOPLASIA

Microglia Activate Migration of Glioma Cells through a Pyk2 Intracellular Pathway

(2015) Kimberleve Rolón-Reyes et al.   PLoS One

Tie2/TEK Modulates the Interaction of Glioma and Brain Tumor Stem Cells with Endothelial Cells and Promotes an Invasive Phenotype

(2015)   Oncotarget

Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells

(2015) Genevieve L. Weber et al.   Oncotarget

Engineering strategies to mimic the glioblastoma microenvironment

(2014) Andrew Rape et al.   ADVANCED DRUG DELIVERY REVIEWS

Spatially Gradated Hydrogel Platform as a 3D Engineered Tumor Microenvironment

(2014) Sara Pedron et al.   ADVANCED MATERIALS

Bioengineered Scaffolds for 3D Analysis of Glioblastoma Proliferation and Invasion

(2014) John M. Heffernan et al.   ANNALS OF BIOMEDICAL ENGINEERING

Proliferation and enrichment of CD133+ glioblastoma cancer stem cells on 3D chitosan-alginate scaffolds

(2014) Forrest M. Kievit et al.   BIOMATERIALS

A composite hydrogel platform for the dissection of tumor cell migration at tissue interfaces

(2014) Andrew D. Rape et al.   BIOMATERIALS

Three-dimensional in vitro tumor models for cancer research and drug evaluation

(2014) Xian Xu et al.   BIOTECHNOLOGY ADVANCES

Live-Cell Imaging of Invasion and Intravasation in an Artificial Microvessel Platform

(2014) Andrew D. Wong et al.   CANCER RESEARCH

HMMR Maintains the Stemness and Tumorigenicity of Glioblastoma Stem-like Cells

(2014) J. Tilghman et al.   CANCER RESEARCH

Upregulation of NHE1 protein expression enables glioblastoma cells to escape TMZ-mediated toxicity via increased H+extrusion, cell migration and survival

(2014) Damin Cong et al.   CARCINOGENESIS

Osteopontin-CD44 Signaling in the Glioma Perivascular Niche Enhances Cancer Stem Cell Phenotypes and Promotes Aggressive Tumor Growth

(2014) Alexander Pietras et al.   Cell Stem Cell

Modeling Tumor Microenvironments In Vitro

(2014) Mingming Wu et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

A co-culture model with brain tumor-specific bioluminescence demonstrates astrocyte-induced drug resistance in glioblastoma

(2014) Ning Yang et al.   Journal of Translational Medicine

Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

(2014) Roger Stupp et al.   LANCET ONCOLOGY

CD44-Mediated Adhesion to Hyaluronic Acid Contributes to Mechanosensing and Invasive Motility

(2014) Yushan Kim et al.   MOLECULAR CANCER RESEARCH

Glycogen Synthase Kinase 3  Sustains Invasion of Glioblastoma via the Focal Adhesion Kinase, Rac1, and c-Jun N-Terminal Kinase-Mediated Pathway

(2014) Y. Chikano et al.   MOLECULAR CANCER THERAPEUTICS

Bioengineered 3D Brain Tumor Model To Elucidate the Effects of Matrix Stiffness on Glioblastoma Cell Behavior Using PEG-Based Hydrogels

(2014) Christine Wang et al.   MOLECULAR PHARMACEUTICS

A neurocentric perspective on glioma invasion

(2014) Vishnu Anand Cuddapah et al.   NATURE REVIEWS NEUROSCIENCE

Microenvironmental Stiffness Enhances Glioma Cell Proliferation by Stimulating Epidermal Growth Factor Receptor Signaling

(2014) Vaibhavi Umesh et al.   PLoS One

Investigation of Adhesion and Mechanical Properties of Human Glioma Cells by Single Cell Force Spectroscopy and Atomic Force Microscopy

(2014) Laura Andolfi et al.   PLoS One

Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration

(2014) J. Pignatelli et al.   Science Signaling

Disruption of astrocyte–vascular coupling and the blood–brain barrier by invading glioma cells

(2014) Stacey Watkins et al.   Nature Communications

Glioblastoma Behaviors in Three-Dimensional Collagen-Hyaluronan Composite Hydrogels

(2013) Shreyas S. Rao et al.   ACS Applied Materials & Interfaces

Mimicking white matter tract topography using core–shell electrospun nanofibers to examine migration of malignant brain tumors

(2013) Shreyas S. Rao et al.   BIOMATERIALS

Porous chitosan-hyaluronic acid scaffolds as a mimic of glioblastoma microenvironment ECM

(2013) Stephen J. Florczyk et al.   BIOMATERIALS

Regulation of glioma cell phenotype in 3D matrices by hyaluronic acid

(2013) Sara Pedron et al.   BIOMATERIALS

ADAM17 promotes U87 glioblastoma stem cell migration and invasion

(2013) Xiangrong Chen et al.   BRAIN RESEARCH

Tenascin-C is expressed by human glioma in vivo and shows a strong association with tumor blood vessels

(2013) Nicole Brösicke et al.   CELL AND TISSUE RESEARCH

Identifying new small molecule anti-invasive compounds for glioma treatment

(2013) Jennifer Munson et al.   CELL CYCLE

Ex vivo cultures of glioblastoma in three-dimensional hydrogel maintain the original tumor growth behavior and are suitable for preclinical drug and radiation sensitivity screening

(2013) Carine Jiguet Jiglaire et al.   EXPERIMENTAL CELL RESEARCH

Impact of the biophysical features of a 3D gelatin microenvironment on glioblastoma malignancy

(2013) S. Pedron et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Bradykinin-Induced Chemotaxis of Human Gliomas Requires the Activation of KCa3.1 and ClC-3

(2013) V. A. Cuddapah et al.   JOURNAL OF NEUROSCIENCE

Microfluidics embedded within extracellular matrix to define vascular architectures and pattern diffusive gradients

(2013) Brendon M. Baker et al.   LAB ON A CHIP

Inhibition of NF- B Signaling Ablates the Invasive Phenotype of Glioblastoma

(2013) M.-A. Westhoff et al.   MOLECULAR CANCER RESEARCH

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2006-2010

(2013) Q. T. Ostrom et al.   NEURO-ONCOLOGY

Astrocytes Enhance the Invasion Potential of Glioblastoma Stem-Like Cells

(2013) Barbara H. Rath et al.   PLoS One

Astrocytes Directly Influence Tumor Cell Invasion and Metastasis In Vivo

(2013) Ling Wang et al.   PLoS One

Recruited Brain Tumor-Derived Mesenchymal Stem Cells Contribute to Brain Tumor Progression

(2013) Jinan Behnan et al.   STEM CELLS

Glioma-Associated Stem Cells: A Novel Class of Tumor-Supporting Cells Able to Predict Prognosis of Human Low-Grade Gliomas

(2013) Evgenia Bourkoula et al.   STEM CELLS

Glioblastoma cancer stem cells: Role of the microenvironment and therapeutic targeting

(2012) Luca Persano et al.   BIOCHEMICAL PHARMACOLOGY

A Genetic Strategy for the Dynamic and Graded Control of Cell Mechanics, Motility, and Matrix Remodeling

(2012) Joanna L. MacKay et al.   BIOPHYSICAL JOURNAL

Interstitial Flow in a 3D Microenvironment Increases Glioma Invasion by a CXCR4-Dependent Mechanism

(2012) J. M. Munson et al.   CANCER RESEARCH

Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells

(2012) Jian Chen et al.   CELL

The regulation of cysteine cathepsins and cystatins in human gliomas

(2012) Boris Gole et al.   INTERNATIONAL JOURNAL OF CANCER

Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF- 1 Signaling Pathway

(2012) X.-z. Ye et al.   JOURNAL OF IMMUNOLOGY

Low-grade glioma surgery in eloquent areas: volumetric analysis of extent of resection and its impact on overall survival. A single-institution experience in 190 patients

(2012) Tamara Ius et al.   JOURNAL OF NEUROSURGERY

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(2012) Salvatore Coniglio et al.   MOLECULAR MEDICINE

In vitro cell migration and invasion assays

(2012) Nina Kramer et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues

(2012) Jordan S. Miller et al.   NATURE MATERIALS

Independent regulation of tumor cell migration by matrix stiffness and confinement

(2012) A. Pathak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

(2012) I. K. Zervantonakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-Invasive Adjuvant Therapy with Imipramine Blue Enhances Chemotherapeutic Efficacy Against Glioma

(2012) J. M. Munson et al.   Science Translational Medicine

Mechanosignaling to the Cell Nucleus and Gene Regulation

(2011) G.V. Shivashankar   Annual Review of Biophysics

Addressing Diffuse Glioma as a Systemic Brain Disease With Single-Cell Analysis

(2011) David Capper   ARCHIVES OF NEUROLOGY

Downregulation of Akt and FAK phosphorylation reduces invasion of glioblastoma cells by impairment of MT1-MMP shuttling to lamellipodia and downregulates MMPs expression

(2011) Aneta Kwiatkowska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform

(2011) Badriprasad Ananthanarayanan et al.   BIOMATERIALS

Microfluidics-based devices: New tools for studying cancer and cancer stem cell migration

(2011) Yu Huang et al.   Biomicrofluidics

Minocycline reduces glioma expansion and invasion by attenuating microglial MT1-MMP expression

(2011) D.S. Markovic et al.   BRAIN BEHAVIOR AND IMMUNITY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway

(2011) L Qiang et al.   CELL DEATH AND DIFFERENTIATION

Deadly Teamwork: Neural Cancer Stem Cells and the Tumor Microenvironment

(2011) Justin D. Lathia et al.   Cell Stem Cell

The brain tumor microenvironment

(2011) Nikki A. Charles et al.   GLIA

RhoA and RhoC have distinct roles in migration and invasion by acting through different targets

(2011) Francisco M. Vega et al.   JOURNAL OF CELL BIOLOGY

Hydrodynamic Cellular Volume Changes Enable Glioma Cell Invasion

(2011) S. Watkins et al.   JOURNAL OF NEUROSCIENCE

Bradykinin Promotes the Chemotactic Invasion of Primary Brain Tumors

(2011) V. Montana et al.   JOURNAL OF NEUROSCIENCE

Interstitial guidance of cancer invasion

(2011) Pavlo G. Gritsenko et al.   JOURNAL OF PATHOLOGY

Contributions of talin-1 to glioma cell-matrix tensional homeostasis

(2011) S. Sen et al.   Journal of the Royal Society Interface

The stem cell potential of glia: lessons from reactive gliosis

(2011) Stefanie Robel et al.   NATURE REVIEWS NEUROSCIENCE

Pathway inhibition: emerging molecular targets for treating glioblastoma

(2011) W. Wick et al.   NEURO-ONCOLOGY

Fluid Shear Stress Regulates the Invasive Potential of Glioma Cells via Modulation of Migratory Activity and Matrix Metalloproteinase Expression

(2011) Henry Qazi et al.   PLoS One

Recruited Cells Can Become Transformed and Overtake PDGF-Induced Murine Gliomas In Vivo during Tumor Progression

(2011) Elena I. Fomchenko et al.   PLoS One

Retaining cell-cell contact enables preparation and culture of spheroids composed of pure primary cancer cells from colorectal cancer

(2011) J. Kondo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extra-Neural Metastases of Malignant Gliomas: Myth or Reality?

(2011) Patrick Beauchesne   Cancers

The Utility and Limitations of Neurosphere Assay, CD133 Immunophenotyping and Side Population Assay in Glioma Stem Cell Research

(2010) Feng Wan et al.   BRAIN PATHOLOGY

A Hierarchy of Self-Renewing Tumor-Initiating Cell Types in Glioblastoma

(2010) Ruihuan Chen et al.   CANCER CELL

Inhibition of the Sodium-Potassium-Chloride Cotransporter Isoform-1 Reduces Glioma Invasion

(2010) B. R. Haas et al.   CANCER RESEARCH

Caffeine-Mediated Inhibition of Calcium Release Channel Inositol 1,4,5-Trisphosphate Receptor Subtype 3 Blocks Glioblastoma Invasion and Extends Survival

(2010) S. S. Kang et al.   CANCER RESEARCH

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

(2010) John M. Heddleston et al.   CELL CYCLE

Acidic stress promotes a glioma stem cell phenotype

(2010) A B Hjelmeland et al.   CELL DEATH AND DIFFERENTIATION

Guidelines on management of low-grade gliomas: report of an EFNS-EANO* Task Force

(2010) R. Soffietti et al.   EUROPEAN JOURNAL OF NEUROLOGY

Hallmarks of cancer: Interactions with the tumor stroma

(2010) Kristian Pietras et al.   EXPERIMENTAL CELL RESEARCH

The perivascular astroglial sheath provides a complete covering of the brain microvessels: An electron microscopic 3D reconstruction

(2010) Thomas Misje Mathiisen et al.   GLIA

Biological applications of microfluidic gradient devices

(2010) Sudong Kim et al.   Integrative Biology

Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer

(2010) Johanna Chiche et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Glioma-initiating cells: A predominant role in microglia/macrophages tropism to glioma

(2010) Liang Yi et al.   JOURNAL OF NEUROIMMUNOLOGY

Actomyosin Contraction at the Cell Rear Drives Nuclear Translocation in Migrating Cortical Interneurons

(2010) F. J. Martini et al.   JOURNAL OF NEUROSCIENCE

Knock down of HIF-1α in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres

(2010) Olga Méndez et al.   Molecular Cancer

Probing Cellular Traction Forces by Micropillar Arrays: Contribution of Substrate Warping to Pillar Deflection

(2010) Ingmar Schoen et al.   NANO LETTERS

Role of hyaluronan in glioma invasion

(2010) Jong Bae Park et al.   Cell Adhesion & Migration

Studying the Effects of Matrix Stiffness on Cellular Function using Acrylamide-based Hydrogels

(2010) Alexandra Cretu et al.   Jove-Journal of Visualized Experiments

Control of 3-dimensional collagen matrix polymerization for reproducible human mammary fibroblast cell culture in microfluidic devices

(2009) Kyung Eun Sung et al.   BIOMATERIALS

Probing cellular mechanobiology in three-dimensional culture with collagen–agarose matrices

(2009) Theresa A. Ulrich et al.   BIOMATERIALS

A novel asymmetric 3D in-vitro assay for the study of tumor cell invasion

(2009) Vera Brekhman et al.   BMC CANCER

Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

(2009) Zhizhong Li et al.   CANCER CELL

The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells

(2009) T. A. Ulrich et al.   CANCER RESEARCH

Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens

(2009) Steven M. Pollard et al.   Cell Stem Cell

Astrocytoma derived short-term cell cultures retain molecular signatures characteristic of the tumour in situ

(2009) Nicola E. Potter et al.   EXPERIMENTAL CELL RESEARCH

Elastin-derived peptides: Matrikines critical for glioblastoma cell aggressiveness in a 3-D system

(2009) Bérénice Coquerel et al.   GLIA

Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin

(2009) A. M. LeBeau et al.   MOLECULAR CANCER THERAPEUTICS

Quantifying the Traction Force of a Single Cell by Aligned Silicon Nanowire Array

(2009) Zhou Li et al.   NANO LETTERS

Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro

(2009) Gabriele D. Maurer et al.   NEURO-ONCOLOGY

Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α

(2009) A Soeda et al.   ONCOGENE

Isoform-Specific Contributions of α-Actinin to Glioma Cell Mechanobiology

(2009) Shamik Sen et al.   PLoS One

Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion

(2009) D. S. Markovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell migration in the normal and pathological postnatal mammalian brain

(2009) Myriam Cayre et al.   PROGRESS IN NEUROBIOLOGY

Cancer associated fibroblasts in cancer pathogenesis

(2009) Omar E. Franco et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression

(2009) Masayuki Shimoda et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Molecular biology of cancer-associated fibroblasts: Can these cells be targeted in anti-cancer therapy?

(2009) Tamas A. Gonda et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Quantitative Analysis of Complex Glioma Cell Migration on Electrospun Polycaprolactone Using Time-Lapse Microscopy

(2009) Jed Johnson et al.   TISSUE ENGINEERING PART C-METHODS

Glioma stem cells are more aggressive in recurrent tumors with malignant progression than in the primary tumor, and both can be maintained long-term in vitro

(2008) Qiang Huang et al.   BMC CANCER

Extracellular matrix of the central nervous system: from neglect to challenge

(2008) Dieter R. Zimmermann et al.   HISTOCHEMISTRY AND CELL BIOLOGY

An efficient method for derivation and propagation of glioblastoma cell lines that conserves the molecular profile of their original tumours

(2008) Talal M. Fael Al-Mayhani et al.   JOURNAL OF NEUROSCIENCE METHODS

Epidermal Growth Factor–induced Enhancement of Glioblastoma Cell Migration in 3D Arises from an Intrinsic Increase in Speed But an Extrinsic Matrix- and Proteolysis-dependent Increase in Persistence

(2008) Hyung-Do Kim et al.   MOLECULAR BIOLOGY OF THE CELL

The Role of Myosin II in Glioma Invasion of the Brain

(2008) Christopher Beadle et al.   MOLECULAR BIOLOGY OF THE CELL

Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain

(2008) A. Buffo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch signaling mediates hypoxia-induced tumor cell migration and invasion

(2008) C. Sahlgren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Co-evolution of tumor cells and their microenvironment

(2008) Kornelia Polyak et al.   TRENDS IN GENETICS