Interstitial flow differentially increases patient-derived glioblastoma stem cell invasion via CXCR4, CXCL12, and CD44-mediated mechanisms

The role of microglia and macrophages in glioma maintenance and progression

(2016) Dolores Hambardzumyan et al.   NATURE NEUROSCIENCE

Cancer stem cells in glioblastoma

(2015) Justin D. Lathia et al.   GENES & DEVELOPMENT

Agent-based model of angiogenesis simulates capillary sprout initiation in multicellular networks

(2015) J. Walpole et al.   Integrative Biology

Interstitial flows promote amoeboid over mesenchymal motility of breast cancer cells revealed by a three dimensional microfluidic model

(2015) Yu Ling Huang et al.   Integrative Biology

Agent-based computational model investigates muscle-specific responses to disuse-induced atrophy

(2015) Kyle S. Martin et al.   JOURNAL OF APPLIED PHYSIOLOGY

The Evidence of Glioblastoma Heterogeneity

(2015) Akio Soeda et al.   Scientific Reports

CD44 Acts as a Signaling Platform Controlling Tumor Progression and Metastasis

(2015) Véronique Orian-Rousseau   Frontiers in Immunology

A Mathematical Model of Collective Cell Migration in a Three-Dimensional, Heterogeneous Environment

(2015) David P. Stonko et al.   PLoS One

A mesenchymal glioma stem cell profile is related to clinical outcome

(2014) A Balbous et al.   Oncogenesis

Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma

(2013) Krishna P.L. Bhat et al.   CANCER CELL

Cancer cell glycocalyx mediates mechanotransduction and flow-regulated invasion

(2013) Henry Qazi et al.   Integrative Biology

Glioblastoma and Other Malignant Gliomas

(2013) Antonio Omuro   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Astrocytes Enhance the Invasion Potential of Glioblastoma Stem-Like Cells

(2013) Barbara H. Rath et al.   PLoS One

Expression and Functional Heterogeneity of Chemokine Receptors CXCR4 and CXCR7 in Primary Patient-Derived Glioblastoma Cells

(2013) Che Liu et al.   PLoS One

Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3

(2013) P. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CXCR4/CXCL12 Axis in Non Small Cell Lung Cancer (NSCLC) Pathologic Roles and Therapeutic Potential

(2013) Ori Wald et al.   Theranostics

Targeting a cornerstone of radiation resistance: Cancer stem cell

(2012) Coralie Moncharmont et al.   CANCER LETTERS

Interstitial Flow in a 3D Microenvironment Increases Glioma Invasion by a CXCR4-Dependent Mechanism

(2012) J. M. Munson et al.   CANCER RESEARCH

Resistance of Glioblastoma-Initiating Cells to Radiation Mediated by the Tumor Microenvironment Can Be Abolished by Inhibiting Transforming Growth Factor-β

(2012) Matthew E. Hardee et al.   CANCER RESEARCH

CXCR4-Positive Subset of Glioma Is Enriched for Cancer Stem Cells

(2012) Xuesheng Zheng et al.   ONCOLOGY RESEARCH

CD44 in human glioma correlates with histopathological grade and cell migration

(2012) Tsuneyasu Yoshida et al.   PATHOLOGY INTERNATIONAL

Anti-Invasive Adjuvant Therapy with Imipramine Blue Enhances Chemotherapeutic Efficacy Against Glioma

(2012) J. M. Munson et al.   Science Translational Medicine

Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform

(2011) Badriprasad Ananthanarayanan et al.   BIOMATERIALS

Shear Stress Regulates Adhesion and Rolling of CD44+ Leukemic and Hematopoietic Progenitor Cells on Hyaluronan

(2011) Christof Christophis et al.   BIOPHYSICAL JOURNAL

Tumor Cell Invasion Is Promoted by Interstitial Flow-Induced Matrix Priming by Stromal Fibroblasts

(2011) A. C. Shieh et al.   CANCER RESEARCH

Migration dynamics of breast cancer cells in a tunable 3D interstitial flow chamber

(2011) Ulrike Haessler et al.   Integrative Biology

Fluid Shear Stress Regulates the Invasive Potential of Glioma Cells via Modulation of Migratory Activity and Matrix Metalloproteinase Expression

(2011) Henry Qazi et al.   PLoS One

Dendritic cell chemotaxis in 3D under defined chemokine gradients reveals differential response to ligands CCL21 and CCL19

(2011) U. Haessler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interstitial flow influences direction of tumor cell migration through competing mechanisms

(2011) W. J. Polacheck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor morphological evolution: directed migration and gain and loss of the self-metastatic phenotype

(2010) Heiko Enderling et al.   Biology Direct

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Astrocyte Elevated Gene-1 Upregulates Matrix Metalloproteinase-9 and Induces Human Glioma Invasion

(2010) Liping Liu et al.   CANCER RESEARCH

CD44 Attenuates Activation of the Hippo Signaling Pathway and Is a Prime Therapeutic Target for Glioblastoma

(2010) Y. Xu et al.   CANCER RESEARCH

An Agent-Based Model of Signal Transduction in Bacterial Chemotaxis

(2010) Jameson Miller et al.   PLoS One

Migration rules: tumours are conglomerates of self-metastases

(2009) H Enderling et al.   BRITISH JOURNAL OF CANCER

Quantitative Analysis of Complex Glioma Cell Migration on Electrospun Polycaprolactone Using Time-Lapse Microscopy

(2009) Jed Johnson et al.   TISSUE ENGINEERING PART C-METHODS

Agent-Based Model of Therapeutic Adipose-Derived Stromal Cell Trafficking during Ischemia Predicts Ability To Roll on P-Selectin

(2009) Alexander M. Bailey et al.   PLoS Computational Biology

A mathematical model for brain tumor response to radiation therapy

(2008) R. Rockne et al.   JOURNAL OF MATHEMATICAL BIOLOGY

CXCR4 Expression is Elevated in Glioblastoma Multiforme and Correlates with an Increase in Intensity and Extent of Peritumoral T2-weighted Magnetic Resonance Imaging Signal Abnormalities

(2008) Charles B. Stevenson et al.   NEUROSURGERY