Targeting the Adenosinergic Axis in Chronic Lymphocytic Leukemia: A Way to Disrupt the Tumor Niche?
出版年份 2018 全文链接
标题
Targeting the Adenosinergic Axis in Chronic Lymphocytic Leukemia: A Way to Disrupt the Tumor Niche?
作者
关键词
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出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 4, Pages 1167
出版商
MDPI AG
发表日期
2018-04-13
DOI
10.3390/ijms19041167
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Hypoxia-induced miR-214 expression promotes tumour cell proliferation and migration by enhancing the Warburg effect in gastric carcinoma cells
- (2018) Liuqing Yang et al. CANCER LETTERS
- The Hypoxia–Adenosine Link during Intestinal Inflammation
- (2018) Jessica L. Bowser et al. JOURNAL OF IMMUNOLOGY
- Activating adenosine A1 receptor accelerates PC12 cell injury via ADORA1/PKC/KATP pathway after intermittent hypoxia exposure
- (2018) Hong-Fang Mei et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- New drug discovery approaches targeting recurrent mutations in chronic lymphocytic leukemia
- (2017) Rupal Tripathi et al. Expert Opinion on Drug Discovery
- The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets
- (2017) Bertrand Allard et al. IMMUNOLOGICAL REVIEWS
- Involvement of adenosine A3 receptors in the chemotactic navigation of macrophages towards apoptotic cells
- (2017) Gergely Joós et al. IMMUNOLOGY LETTERS
- Emergence of CD26+ Cancer Stem Cells with Metastatic Properties in Colorectal Carcinogenesis
- (2017) Alvin Cheung et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- mRNA overexpression of the hypoxia inducible factor 1 alpha subunit gene (HIF1A): An independent predictor of poor overall survival in chronic lymphocytic leukemia
- (2017) Christos K. Kontos et al. LEUKEMIA RESEARCH
- The potential of P2X7 receptors as a therapeutic target, including inflammation and tumour progression
- (2017) Geoffrey Burnstock et al. Purinergic Signalling
- The adenosine A2b receptor promotes tumor progression of bladder urothelial carcinoma by enhancing MAPK signaling pathway
- (2017) Yihong Zhou et al. Oncotarget
- Accomplices of the Hypoxic Tumor Microenvironment Compromising Antitumor Immunity: Adenosine, Lactate, Acidosis, Vascular Endothelial Growth Factor, Potassium Ions, and Phosphatidylserine
- (2017) Peter Vaupel et al. Frontiers in Immunology
- Prostaglandin EP2 receptor signaling protects human trabecular meshwork cells from apoptosis induced by ER stress through down-regulation of p53
- (2016) Georges Kalouche et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- HIF-1 regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment
- (2016) R. Valsecchi et al. BLOOD
- Abstract 1476: A therapeutic antibody that inhibits CD73 activity by dual mechanisms
- (2016) Bryan C. Barnhart et al. CANCER RESEARCH
- Adenosine 2B Receptor Expression on Cancer Cells Promotes Metastasis
- (2016) D. Mittal et al. CANCER RESEARCH
- Immunosuppressive activities of adenosine in cancer
- (2016) Bertrand Allard et al. CURRENT OPINION IN PHARMACOLOGY
- CD73–adenosine: a next-generation target in immuno-oncology
- (2016) David Allard et al. Immunotherapy
- The prognostic significance of surface dipeptidylpeptidase IV (CD26) expression in B-cell chronic lymphocytic leukemia
- (2016) Magdalena Matuszak et al. LEUKEMIA RESEARCH
- Extracellular purines, purinergic receptors and tumor growth
- (2016) F Di Virgilio et al. ONCOGENE
- Prognostic factors and risk stratification in chronic lymphocytic leukemia
- (2016) Sameer A. Parikh et al. SEMINARS IN ONCOLOGY
- HPLC-based Assay to Monitor Extracellular Nucleotide/Nucleoside Metabolism in Human Chronic Lymphocytic Leukemia Cells
- (2016) Sara Serra et al. Jove-Journal of Visualized Experiments
- Targeting CD73 in the tumor microenvironment with MEDI9447
- (2016) Carl M. Hay et al. OncoImmunology
- Understanding the roles of the P2X7 receptor in solid tumour progression and therapeutic perspectives
- (2015) Sébastien Roger et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Mechanisms of PD-L1/PD-1-mediated CD8 T-cell dysfunction in the context of aging-related immune defects in the E -TCL1 CLL mouse model
- (2015) F. McClanahan et al. BLOOD
- CD49d and CD26 are independent prognostic markers for disease progression in patients with chronic lymphocytic leukemia
- (2015) Lamia Ibrahem et al. BLOOD CELLS MOLECULES AND DISEASES
- Emerging Roles of P2X Receptors in Cancer
- (2015) Elena Adinolfi et al. CURRENT MEDICINAL CHEMISTRY
- Metabolic plasticity in CLL: adaptation to the hypoxic niche
- (2015) K M Koczula et al. LEUKEMIA
- Depletion of CLL-associated patrolling monocytes and macrophages controls disease development and repairs immune dysfunction in vivo
- (2015) B S Hanna et al. LEUKEMIA
- Nurse like cells: chronic lymphocytic leukemia associated macrophages
- (2015) Frédéric Boissard et al. LEUKEMIA & LYMPHOMA
- Glycolysis controls the induction of human regulatory T cells by modulating the expression of FOXP3 exon 2 splicing variants
- (2015) Veronica De Rosa et al. NATURE IMMUNOLOGY
- Adenosine Receptor 2A Blockade Increases the Efficacy of Anti–PD-1 through Enhanced Antitumor T-cell Responses
- (2015) Paul A. Beavis et al. Cancer Immunology Research
- Predicting Prognosis in Chronic Lymphocytic Leukemia in the Contemporary Era
- (2015) Chadi Nabhan et al. JAMA Oncology
- Host A2B Adenosine Receptors Promote Carcinoma Growth
- (2015) Sergey Ryzhov et al. NEOPLASIA
- Blockade of A2b Adenosine Receptor Reduces Tumor Growth and Immune Suppression Mediated by Myeloid-Derived Suppressor Cells in a Mouse Model of Melanoma
- (2015) Raffaella Iannone et al. NEOPLASIA
- Atorvastatin prevents ATP-driven invasiveness via P2X7 and EHBP1 signaling in PTEN-expressing prostate cancer cells
- (2014) Aram Ghalali et al. CARCINOGENESIS
- Enzymes involved in metabolism of extracellular nucleotides and nucleosides: Functional implications and measurement of activities
- (2014) Gennady G. Yegutkin CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Inhibition of T cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (Review)
- (2014) David Hoskin et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- CD73 Participates in Cellular Multiresistance Program and Protects against TRAIL-Induced Apoptosis
- (2014) A. Mikhailov et al. JOURNAL OF IMMUNOLOGY
- Ectonucleoside triphosphate diphosphohydrolase-1 (E-NTPDase1/CD39) as a new prognostic marker in chronic lymphocytic leukemia
- (2014) Nashwa Khairat Abousamra et al. LEUKEMIA & LYMPHOMA
- NOTCH1, SF3B1, BIRC3andTP53mutations in patients with chronic lymphocytic leukemia undergoing first-line treatment: correlation with biological parameters and response to treatment
- (2014) Sabina Chiaretti et al. LEUKEMIA & LYMPHOMA
- Moonlighting Adenosine Deaminase: A Target Protein for Drug Development
- (2014) Antoni Cortés et al. MEDICINAL RESEARCH REVIEWS
- Targeting Cancer-Derived Adenosine:New Therapeutic Approaches
- (2014) A. Young et al. Cancer Discovery
- Hostile, Hypoxia-A2-Adenosinergic Tumor Biology as the Next Barrier to Overcome for Tumor Immunologists
- (2014) M. V. Sitkovsky et al. Cancer Immunology Research
- Targeting CD73 Enhances the Antitumor Activity of Anti-PD-1 and Anti-CTLA-4 mAbs
- (2013) B. Allard et al. CLINICAL CANCER RESEARCH
- Anti-CD73 therapy impairs tumor angiogenesis
- (2013) Bertrand Allard et al. INTERNATIONAL JOURNAL OF CANCER
- HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
- (2013) Gregg L. Semenza JOURNAL OF CLINICAL INVESTIGATION
- Adenosine A2A Receptor as a Drug Discovery Target
- (2013) Manuel de Lera Ruiz et al. JOURNAL OF MEDICINAL CHEMISTRY
- Targeting the hypoxia-adenosinergic signaling pathway to improve the adoptive immunotherapy of cancer
- (2013) Michail Sitkovsky et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Microenvironmental regulation of tumor progression and metastasis
- (2013) Daniela F Quail et al. NATURE MEDICINE
- CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer
- (2013) S. Loi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Blockade of A2Areceptors potently suppresses the metastasis of CD73+tumors
- (2013) Paul A. Beavis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Purinergic signalling and cancer
- (2013) Geoffrey Burnstock et al. Purinergic Signalling
- The microenvironment in chronic lymphocytic leukemia (CLL) and other B cell malignancies: Insight into disease biology and new targeted therapies
- (2013) Jan A. Burger et al. SEMINARS IN CANCER BIOLOGY
- CD39 and CD73 in immunity and inflammation
- (2013) Luca Antonioli et al. TRENDS IN MOLECULAR MEDICINE
- Increased CD39 expression on CD4+ T lymphocytes has clinical and prognostic significance in chronic lymphocytic leukemia
- (2012) Chava Perry et al. ANNALS OF HEMATOLOGY
- Immunogenic Cell Death in Cancer Therapy
- (2012) Guido Kroemer et al. Annual Review of Immunology
- CD73-Deficient Mice Are Resistant to Carcinogenesis
- (2012) J. Stagg et al. CANCER RESEARCH
- Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies
- (2012) I. Verbrugge et al. CANCER RESEARCH
- CD73 and adenosine generation in the creation of regulatory microenvironments
- (2012) F. S. Regateiro et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Impairment of adenosine A3 receptor activity disrupts neutrophil migratory capacity and impacts innate immune function in vivo
- (2012) Matt Butler et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Regulation of CLL survival by hypoxia-inducible factor and its target genes
- (2012) Idit Shachar et al. FEBS LETTERS
- Macrophage plasticity and polarization: in vivo veritas
- (2012) Antonio Sica et al. JOURNAL OF CLINICAL INVESTIGATION
- Transcriptional control of adenosine signaling by hypoxia-inducible transcription factors during ischemic or inflammatory disease
- (2012) Jens M. Poth et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function
- (2012) D J DiLillo et al. LEUKEMIA
- ENTPD1/CD39 is a promising therapeutic target in oncology
- (2012) J Bastid et al. ONCOGENE
- Adenosine as an endogenous immunoregulator in cancer pathogenesis: where to go?
- (2012) V. Kumar Purinergic Signalling
- CD73: a potent suppressor of antitumor immune responses
- (2012) Paul. A. Beavis et al. TRENDS IN IMMUNOLOGY
- CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death
- (2011) S. Serra et al. BLOOD
- Enhancement of tumor immunotherapy by deletion of the A2A adenosine receptor
- (2011) Adam T. Waickman et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- CD73-Deficient Mice Have Increased Antitumor Immunity and Are Resistant to Experimental Metastasis
- (2011) J. Stagg et al. CANCER RESEARCH
- CD39 Expression on T Lymphocytes Correlates With Severity of Disease in Patients With Chronic Lymphocytic Leukemia
- (2011) Dianne Pulte et al. Clinical Lymphoma Myeloma & Leukemia
- CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice
- (2011) Long Wang et al. JOURNAL OF CLINICAL INVESTIGATION
- Adenosine A2B Receptor Blockade Slows Growth of Bladder and Breast Tumors
- (2011) C. Cekic et al. JOURNAL OF IMMUNOLOGY
- Activation and Regulation of Purinergic P2X Receptor Channels
- (2011) C. Coddou et al. PHARMACOLOGICAL REVIEWS
- Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice
- (2011) M. Michaud et al. SCIENCE
- Adenosine receptors and cancer
- (2010) Stefania Gessi et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Soluble CD14 is a novel monocyte-derived survival factor for chronic lymphocytic leukemia cells, which is induced by CLL cells in vitro and present at abnormally high levels in vivo
- (2010) M. Seiffert et al. BLOOD
- CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression
- (2010) D. Jin et al. CANCER RESEARCH
- Adenosine A2A receptor activation protects CD4+ T lymphocytes against activation-induced cell death
- (2010) Leonóra Himer et al. FASEB JOURNAL
- CD39/ENTPD1 Expression by CD4+Foxp3+ Regulatory T Cells Promotes Hepatic Metastatic Tumor Growth in Mice
- (2010) Xiaofeng Sun et al. GASTROENTEROLOGY
- Monoclonal antibody–assisted stimulation of adenosine A2A receptors induces simultaneous downregulation of CXCR4 and CCR5 on CD4+ T-cells
- (2010) Youlet By et al. HUMAN IMMUNOLOGY
- Much Ado about Adenosine: Adenosine Synthesis and Function in Regulatory T Cell Biology
- (2010) P. B. Ernst et al. JOURNAL OF IMMUNOLOGY
- Extracellular adenosine triphosphate and adenosine in cancer
- (2010) J Stagg et al. ONCOGENE
- Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis
- (2010) J. Stagg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD38 as a molecular compass guiding topographical decisions of chronic lymphocytic leukemia cells
- (2010) Silvia Deaglio et al. SEMINARS IN CANCER BIOLOGY
- Abnormal expression of P2X family receptors in Chinese pediatric acute leukemias
- (2009) Jing-Hui Chong et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia
- (2009) C. Calissano et al. BLOOD
- Serum level of CD26 predicts time to first treatment in early B-chronic lymphocytic leukemia
- (2009) Stefano Molica et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- CD26 expression in mature B-cell neoplasia: its possible role as a new prognostic marker in B-CLL
- (2009) Lilla Cro et al. HEMATOLOGICAL ONCOLOGY
- Human Follicular Lymphoma CD39+-Infiltrating T Cells Contribute to Adenosine-Mediated T Cell Hyporesponsiveness
- (2009) S. P. Hilchey et al. JOURNAL OF IMMUNOLOGY
- Enhanced formation and survival of CD4+CD25hiFoxp3+T-cells in chronic lymphocytic leukemia
- (2009) Margot Jak et al. LEUKEMIA & LYMPHOMA
- Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
- (2009) Michael R. Elliott et al. NATURE
- E -TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction
- (2009) G. Gorgun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Extracellular ATP in the Immune System: More Than Just a "Danger Signal"
- (2009) A. Trautmann Science Signaling
- Signaling at Purinergic P2X Receptors
- (2008) Annmarie Surprenant et al. Annual Review of Physiology
- Hypoxia-Adenosinergic Immunosuppression: Tumor Protection by T Regulatory Cells and Cancerous Tissue Hypoxia
- (2008) M. V. Sitkovsky et al. CLINICAL CANCER RESEARCH
- Novel Insights in Chronic Lymphocytic Leukemia: Are We Getting Closer to Understanding the Pathogenesis of the Disease?
- (2008) Federico Caligaris-Cappio et al. JOURNAL OF CLINICAL ONCOLOGY
- Adenosine receptors: therapeutic aspects for inflammatory and immune diseases
- (2008) György Haskó et al. NATURE REVIEWS DRUG DISCOVERY
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