The Modulatory Roles of N-glycans in T-Cell-Mediated Autoimmune Diseases

Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation

(2017) Lindsey Araujo et al.   eLife

Core Fucosylation on T Cells, Required for Activation of T-Cell Receptor Signaling and Induction of Colitis in Mice, Is Increased in Patients With Inflammatory Bowel Disease

(2016) Hironobu Fujii et al.   GASTROENTEROLOGY

Glycobiology simplified: diverse roles of glycan recognition in inflammation

(2016) Ronald L. Schnaar   JOURNAL OF LEUKOCYTE BIOLOGY

Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis

(2016) Haik Mkhikian et al.   eLife

Pancreatic β-Cells Limit Autoimmune Diabetes via an Immunoregulatory Antimicrobial Peptide Expressed under the Influence of the Gut Microbiota

(2015) Jia Sun et al.   IMMUNITY

Glucosamine Modulates T Cell Differentiation through Down-regulatingN-Linked Glycosylation of CD25

(2015) Ming-Wei Chien et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutrophil-related factors as biomarkers in EAE and MS

(2015) Julie M. Rumble et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Family studies of type 1 diabetes reveal additive and epistatic effects between MGAT1 and three other polymorphisms

(2014) Z Yu et al.   GENES AND IMMUNITY

N-glycosylation bidirectionally extends the boundaries of thymocyte positive selection by decoupling Lck from Ca2+ signaling

(2014) Raymond W Zhou et al.   NATURE IMMUNOLOGY

Glucosamine-Induced OGT Activation Mediates Glucose Production Through Cleaved Notch1 and FoxO1, Which Coordinately Contributed to the Regulation of Maintenance of Self-Renewal in Mouse Embryonic Stem Cells

(2014) Ji Hoon Jeon et al.   STEM CELLS AND DEVELOPMENT

Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology

(2013) Catharina Steentoft et al.   EMBO JOURNAL

Dysregulation of T cell receptor N-glycosylation: a molecular mechanism involved in ulcerative colitis

(2013) Ana M. Dias et al.   HUMAN MOLECULAR GENETICS

Mucin-typeO-Glycosylation during Development

(2013) Duy T. Tran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IFN-γ receptor deficiency prevents diabetes induction by diabetogenic CD4+, but not CD8+, T cells

(2012) Zuoan Yi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inducible colitis-associated glycome capable of stimulating the proliferation of memory CD4+T cells

(2012) Atsushi Nishida et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Glycosylation, galectins and cellular signaling

(2011) Cecile Boscher et al.   CURRENT OPINION IN CELL BIOLOGY

Control of mucin-type O-glycosylation: A classification of the polypeptide GalNAc-transferase gene family

(2011) E. P. Bennett et al.   GLYCOBIOLOGY

N-Acetylglucosamine Inhibits T-helper 1 (Th1)/T-helper 17 (Th17) Cell Responses and Treats Experimental Autoimmune Encephalomyelitis

(2011) Ani Grigorian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Murine Models of Systemic Lupus Erythematosus

(2011) Daniel Perry et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport

(2011) Kazuaki Ohtsubo et al.   NATURE MEDICINE

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Glucosamine Improved Atopic Dermatitis-like Skin Lesions in NC/Nga Mice by Inhibition of Th2 Cell Development

(2011) C.-H. Kim et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis

(2011) Haik Mkhikian et al.   Nature Communications

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

Animal models of IBD: linkage to human disease

(2010) Atsushi Mizoguchi et al.   CURRENT OPINION IN PHARMACOLOGY

Therapeutic Strategies for SLE Involving Cytokines: Mechanism-Oriented Therapies Especially IFN- Targeting Gene Therapy

(2010) Toshiharu Hayashi   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Cytokines and Their Roles in the Pathogenesis of Systemic Lupus Erythematosus: From Basics to Recent Advances

(2010) Desmond Yat Hin Yap et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Cosmc is an essential chaperone for correct protein O-glycosylation

(2010) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4+ T Cells

(2010) J. J. O'Shea et al.   SCIENCE

Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O-GlcNAcase

(2009) Matthew S. Macauley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: Implications for Th17-mediated inflammation in auto-immunity

(2008) Chun Kwok Wong et al.   CLINICAL IMMUNOLOGY

Galectins: structure, function and therapeutic potential

(2008) Ri-Yao Yang et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Immunocytochemical analysis for intracellular dynamics of C1GalT associated with molecular chaperone, Cosmc

(2007) Yoshiki Narimatsu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS