NSC 95397 Suppresses Proliferation and Induces Apoptosis in Colon Cancer Cells through MKP-1 and the ERK1/2 Pathway

DUSP1 inhibits cell proliferation, metastasis and invasion and angiogenesis in gallbladder cancer

(2017) Jiliang Shen et al.   Oncotarget

p21(WAF1) Mediates Cell-Cycle Inhibition, Relevant to Cancer Suppression and Therapy

(2016) Wafik S. El-Deiry   CANCER RESEARCH

Stimulation of Suicidal Erythrocyte Death by the CDC25 Inhibitor NSC-95397

(2016) Mohamed Jemaà et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Disruption of a regulatory loop between DUSP1 and p53 contributes to hepatocellular carcinoma development and progression

(2015) Pei-Pei Hao et al.   JOURNAL OF HEPATOLOGY

Ailanthone Inhibits Huh7 Cancer Cell Growth via Cell Cycle Arrest and Apoptosis In Vitro and In Vivo

(2015) Zhenjian Zhuo et al.   Scientific Reports

Dual-specificity phosphatases: critical regulators with diverse cellular targets

(2015) Kate I. Patterson et al.   BIOCHEMICAL JOURNAL

FOXF1 mediates mesenchymal stem cell fusion-induced reprogramming of lung cancer cells

(2015) Hong-Jian Wei et al.   Oncotarget

Novel anti-inflammatory function of NSC95397 by the suppression of multiple kinases

(2014) Yanyan Yang et al.   BIOCHEMICAL PHARMACOLOGY

DUSP1 Phosphatase Regulates the Proinflammatory Milieu in Head and Neck Squamous Cell Carcinoma

(2014) X. Zhang et al.   CANCER RESEARCH

Involvement of MAPK Phosphatase-1 in Dexamethasone-Induced Chemoresistance in Lung Cancer

(2014) Jian Huang et al.   JOURNAL OF CHEMOTHERAPY

DUSP1 Is a Novel Target for Enhancing Pancreatic Cancer Cell Sensitivity to Gemcitabine

(2014) Fang Liu et al.   PLoS One

Hinokitiol Induces DNA Damage and Autophagy followed by Cell Cycle Arrest and Senescence in Gefitinib-Resistant Lung Adenocarcinoma Cells

(2014) Lan-Hui Li et al.   PLoS One

Drug Resistance in Cancer: An Overview

(2014) Genevieve Housman et al.   Cancers

Mitogen-activated protein kinase phosphatase-1 inhibition and sustained extracellular signal-regulated kinase 1/2 activation in camptothecin-induced human colon cancer cell death

(2013) Minyoung Lee et al.   CANCER BIOLOGY & THERAPY

Hinokitiol Inhibits Cell Growth through Induction of S-Phase Arrest and Apoptosis in Human Colon Cancer Cells and Suppresses Tumor Growth in a Mouse Xenograft Experiment

(2013) Youn-Sun Lee et al.   JOURNAL OF NATURAL PRODUCTS

Cellular Mechanisms Controlling Caspase Activation and Function

(2013) A. B. Parrish et al.   Cold Spring Harbor Perspectives in Biology

Enhancement of Cisplatin-Mediated Apoptosis in Ovarian Cancer Cells through Potentiating G2/M Arrest and p21 Upregulation by Combinatorial Epigallocatechin Gallate and Sulforaphane

(2013) Huaping Chen et al.   Journal of Oncology

Mitogen-activated protein kinase phosphatase-1 (MKP-1) impairs the response to anti-epidermal growth factor receptor (EGFR) antibody cetuximab in metastatic colorectal cancer patients

(2010) C Montagut et al.   BRITISH JOURNAL OF CANCER

DUSP1/MKP1 promotes angiogenesis, invasion and metastasis in non-small-cell lung cancer

(2010) V Moncho-Amor et al.   ONCOGENE

ERK and cell death: Mechanisms of ERK-induced cell death - apoptosis, autophagy and senescence

(2009) Sebastien Cagnol et al.   FEBS Journal

Dual-Specificity Phosphatase 1 Ubiquitination in Extracellular Signal-Regulated Kinase-Mediated Control of Growth in Human Hepatocellular Carcinoma

(2008) D. F. Calvisi et al.   CANCER RESEARCH

Involvement of miltefosine-mediated ERK activation in glioma cell apoptosis through Fas regulation

(2008) Richa Tewari et al.   JOURNAL OF NEUROCHEMISTRY

A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells

(2008) A. Vogt et al.   MOLECULAR CANCER THERAPEUTICS