Article
Environmental Sciences
Shruti Bindal, Saurabh Kadyan, Meenu Saini, Rani Gupta
Summary: This study utilizes keratinolytic microbes and their enzymes for the degradation of animal hair waste and the production of value-added products. The results show that protease production can be enhanced through medium optimization strategies. The developed enzymatic method allows for lime and sulfite-free hide dehairing and conversion of hair waste into valuable products.
WASTE AND BIOMASS VALORIZATION
(2022)
Article
Biotechnology & Applied Microbiology
Jinfang Zhang, Baoyue Zhu, Xinyue Li, Xiaojian Xu, Dengke Li, Fang Zeng, Cuixia Zhou, Yihan Liu, Yu Li, Fuping Lu
Summary: Bacillus amyloliquefaciens is a microorganism with great potential for the production of heterologous proteins. In this study, the key modules affecting the production of alkaline proteases were identified as the sporulation germination module, extracellular protease synthesis module, and extracellular polysaccharide synthesis module. Mutations in these modules significantly increased the production of alkaline proteases.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Rong-Xian Zhang, Zhong-Wei Wu, Hai-Yang Cui, Ying-Nan Chai, Cheng-Wei Hua, Peng Wang, Lan Li, Tian-You Yang
Summary: With the improvement of medium components and culture conditions, the production of keratinase by Bacillus cereus YQ15 was increased, and the keratinase showed excellent stability and high efficiency in detergent.
Article
Biotechnology & Applied Microbiology
Nonso E. Nnolim, Anthony I. Okoh, Uchechukwu U. Nwodo
Summary: This study utilized Bacillus sp. Okoh-K1 isolated from a municipal waste dumpsite to produce keratinase, optimized the production conditions, and characterized the enzyme. The keratinase exhibited excellent catalytic activity and stability, showing great potential for biotechnology and industrial applications.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2021)
Article
Biotechnology & Applied Microbiology
Polson Mahakhan, Patapee Apiso, Kannika Srisunthorn, Kanit Vichitphan, Sukanda Vichitphan, Sukrita Punyauppa-path, Jutaporn Sawaengkaew
Summary: Protease is a widely used enzyme in the detergent industry. This research aimed to isolate alkaline protease-producing bacteria and characterize them as laundry detergent additives. The highest alkaline protease-producing bacterium, identified as Bacillus gibsonii, exhibited stability at a pH range of 7.0-12.0 and a temperature of 45 degrees C. The alkaline protease from B. gibsonii showed efficiency in blood stain removal and could be used as a detergent additive with potential applications in various industries.
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Multidisciplinary Sciences
Ge Zhang, Fan Wang, Shuaijun Deng, Guoqiang Chen, Haobao Liu, Haibo Zhang
Summary: This study aimed to obtain a strain capable of producing pectate lyase with good pH stability. Bacillus altitudinis CAS-WZS-08, producing pectate lyase with good pH stability, was isolated. The optimal fermentation conditions for pectate lyase production were determined, and the purified protein was identified as pectate lyase with excellent juice extraction ability.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Jinfang Zhang, Xiaojian Xu, Xinyue Li, Xuejia Chen, Cuixia Zhou, Yihan Liu, Yu Li, Fuping Lu
Summary: By deleting specific genes, autolysis in Bacillus amyloliquefaciens during extracellular protein production can be reduced, leading to increased yield. This systematic deletion of multiple peptidoglycan hydrolases provides a useful strategy for manipulating the genomes of other B. amyloliquefaciens chassis hosts.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Fabian Falkenberg, Jade Rahba, David Fischer, Michael Bott, Johannes Bongaerts, Petra Siegert
Summary: The study characterized a high-alkaline subtilisin and found that it retains good activity under high salt concentrations and high temperatures. It also demonstrated high oxidative stability to hydrogen peroxide, making it a promising candidate for biotechnological applications.
Article
Biotechnology & Applied Microbiology
Douglas A. S. Grahame, John H. Dupuis, Brian C. Bryksa, Takuji Tanaka, Rickey Y. Yada
Summary: The study aimed to determine the structural determinants of aspartic protease stability and activity at high pH levels. It revealed that certain mutants showed increased activity and maintained native-like structure at elevated pH, concluding that reducing electrostatic repulsions and understanding the hydrogen bonding network of the characteristic 13-barrel are crucial for alkaline stabilization of pepsin.
ENZYME AND MICROBIAL TECHNOLOGY
(2021)
Article
Engineering, Biomedical
Mohamed Lamine Talbi, Philippe Ravier
Summary: This paper proposes a flexible modeling technique for ECG signals, where the cardiac cycle is modeled by a weighted summation of elementary functions representing each waveform component. The study shows that alpha-stable modeling outperforms Gaussian modeling in terms of modeling precision and achieves good performance in ECG signal compression.
MEDICAL ENGINEERING & PHYSICS
(2022)
Article
Engineering, Electrical & Electronic
Shengyang Luan, Minglong Zhao, Yinrui Gao, Zhaojun Zhang, Tianshuang Qiu
Summary: Direction of arrival (DOA) estimation is a crucial technique applied in engineering applications, with multiple signal classification (MUSIC) gaining attention for its high resolution. The generalized covariance (GC) concept is proposed to handle noise, with different nonlinear functions introduced for GC and BNC to suppress outliers effectively. By comparing performances with other algorithms, GC-MUSIC and BNC-MUSIC show superiority under Alpha-stable distributed noise through Monte-Carlo simulations.
DIGITAL SIGNAL PROCESSING
(2021)
Article
Environmental Sciences
Bahri Devrim Ozcan, Elif Dikkaya, Makbule Baylan, Gamze Mazi
Summary: In this study, a Bacillus strain FEB5 producing alpha-amylase was isolated from soil samples collected at Cukurova University campus area. The strain was identified as Bacillus pacificus based on 16S rDNA nucleotide sequence analysis. The alpha-amylase from B. pacificus FEB5 showed maximum activity at pH 11.0 and 40 degrees C. The enzyme retained activity after pre-incubation at 40 degrees C, but lost activity gradually above 70 degrees C. The enzyme reached its highest activity level 24 hours after inoculation. SDS-PAGE and zymogram analysis revealed two alpha-amylase bands with molecular weights of 16.5 and 8.3 kDa.
FRESENIUS ENVIRONMENTAL BULLETIN
(2022)
Article
Engineering, Marine
Chunlong Huang, Wenwen Zhou, Qian Cheng, Ran Cao
Summary: This paper investigates the amplitude distribution characteristics of water entry sound to develop a detection method based on probability distribution function change. The results show that water entry sound exhibits significant non-Gaussian characteristics, and the stable distribution model is more suitable than the normal distribution model for water entry noise. The characteristic exponent a plays a crucial role in describing the probability distribution function of water entry sound.
Article
Fisheries
Yuting Lu, Yilin Zhang, Peijun Zhang, Jia Liu, Bo Wang, Xianglu Bu, Qianyan Wei, Shaojun Liu, Yuehong Li
Summary: Salinity and alkalinity are important indicators of the aquatic environment. Probiotic supplementation with Bacillus subtilis can enhance immunity and antioxidant ability, and reduce tissue damage in fish exposed to saline-alkali stress.
AQUACULTURE INTERNATIONAL
(2022)
Article
Biotechnology & Applied Microbiology
Nihan Arabaci, Tuna Karaytug
Summary: This study successfully isolated an alkaline thermophilic protease from a Bacillus strain, and investigated its usability as a detergent bio-additive. The protease showed high activity and stability, and was able to effectively remove protein-based stains. Therefore, it has the potential to be used as a biological additive in laundry detergents.
INDIAN JOURNAL OF MICROBIOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Amal Hammami, Ahmed Bayoudh, Ola Abdelhedi, Moncef Nasri
ANNALS OF MICROBIOLOGY
(2018)
Article
Chemistry, Multidisciplinary
Rim Nasri, Ola Abdelhedi, Ines Jemil, Ikram Ben Amor, Abdelfattah Elfeki, Jalel Gargouri, Ahmed Boualga, Maha Karra-Chaabouni, Moncef Nasri
Article
Chemistry, Applied
Ola Abdelhedi, Mourad Jridi, Rim Nasri, Leticia Mora, Fidel Toldra, Moncef Nasri
FOOD HYDROCOLLOIDS
(2019)
Article
Biochemistry & Molecular Biology
Mourad Jridi, Rim Nasri, Zeineb Marzougui, Ola Abdelhedi, Marwa Hamdi, Moncef Nasri
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2019)
Article
Chemistry, Medicinal
Ola Abdelhedi, Hana Khemakhem, Rim Nasri, Mourad Jridi, Leticia Mora, Ikram Ben Amor, Kamel Jamoussi, Fidel Toldra, Jalel Gargouri, Moncef Nasri
Article
Biotechnology & Applied Microbiology
Fatma Rmili, Neila Achouri, Nabil Smichi, Najeh Krayem, Ahmed Bayoudh, Youssef Gargouri, Mohamed Chamkha, Ahmed Fendri
BIOTECHNOLOGY PROGRESS
(2019)
Article
Chemistry, Applied
Mourad Jridi, Ola Abdelhedi, Nacim Zouari, Nahed Fakhfakh, Moncef Nasri
FOOD HYDROCOLLOIDS
(2019)
Review
Food Science & Technology
Ola Abdelhedi, Moncef Nasri
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2019)
Article
Food Science & Technology
Mourad Jridi, Soumaya Boughriba, Ola Abdelhedi, Hend Nciri, Rim Nasri, Hela Kchaou, Murat Kaya, Hichem Sebai, Nacim Zouari, Moncef Nasri
FOOD PACKAGING AND SHELF LIFE
(2019)
Article
Food Science & Technology
Mourad Jridi, Ola Abdelhedi, Hela Kchaou, Lotfi Msaddak, Moncef Nasri, Nacim Zouari, Nahed Fakhfakh
Article
Biotechnology & Applied Microbiology
Aural Hammami, Ahmed Bayoudh, Bilel Hadrich, Ola Abdelhedi, Mourad Jridi, Moncef Nasri
BIOTECHNOLOGY PROGRESS
(2020)
Article
Food Science & Technology
Ola Abdelhedi, Ali Salem, Nabil Souissi, Rim Nasri, Moncef Nasri, Mourad Jridi
Article
Chemistry, Applied
Mourad Jridi, Ola Abdelhedi, Ali Salem, Hela Kechaou, Moncef Nasri, Yosra Menchari
FOOD HYDROCOLLOIDS
(2020)
Article
Biochemistry & Molecular Biology
Ali Salem, Nahed Fakhfakh, Mourad Jridi, Ola Abdelhedi, Moncef Nasri, Frederic Debeaufort, Nacim Zouari
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2020)
Article
Chemistry, Multidisciplinary
Nabil Souissi, Soumaya Boughriba, Ola Abdelhedi, Marwa Hamdi, Mourad Jridi, Suming Li, Moncef Nasri
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)