Article
Biochemistry & Molecular Biology
Piyachat Chuysinuan, Patcharakamon Nooeaid, Thanyaluck Thanyacharoen, Supanna Techasakul, Prasit Pavasant, Kavita Kanjanamekanant
Summary: The study demonstrates the potential use of synthetic HA-incorporated fibroin-alginate hydrogel as a scaffold for bone regeneration in dentistry, showing good biocompatibility. The hydrogel exhibits high swelling ratio and degradation properties in vitro, but further in vivo studies are needed to validate its clinical application potential.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Materials Science, Ceramics
Sikta Panda, Chandan Kumar Biswas, Subhankar Paul
Summary: Hydroxyapatite has been widely used in bone tissue engineering due to its similarity to human bone, with the possibility of enhancing its properties by replacing calcium with other dopants. The review discusses various coating agents and methods for HAP, as well as different doping materials, effects, and applications in medical procedures. Research articles are analyzed to provide a detailed overview of the topic.
CERAMICS INTERNATIONAL
(2021)
Article
Biochemistry & Molecular Biology
Yunfei Tan, Lei Ma, Xiangyu Chen, Yaqin Ran, Qiulan Tong, Liwen Tang, Xudong Li
Summary: The interfacial mismatch between rigid hydroxyapatite and soft polysaccharide phase in natural polysaccharide/hydroxyapatite hydrogels remains a challenge in bone tissue engineering. In this study, hyaluronic acid was used as a template for biological mineralization to synthesize hyaluronic acid/hydroxyapatite hybrid particles. These particles were then introduced into hydroxyapatite composite hydrogels, which showed increased storage modulus and excellent cytocompatibility. The self-healing hydrogels, suitable for cell encapsulation, hold promise for bone defect repair.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Engineering, Biomedical
Mahsa Janmohammadi, Zahra Nazemi, Amin Orash Mahmoud Salehi, Amir Seyfoori, Johnson John, Mohammad Sadegh Nourbakhsh, Mohsen Akbari
Summary: Cellulose-based scaffolds have great potential in bone tissue engineering due to their non-toxicity, biocompatibility, renewable nature, and low cost. They can deliver growth factors and antibiotics directly to the site of impaired bone tissue to promote tissue repair. This review focuses on the various types of cellulose-based composite scaffolds used for bone drug delivery systems and bone regeneration, highlighting their physicochemical, mechanical, and biological properties.
BIOACTIVE MATERIALS
(2023)
Article
Polymer Science
Diana-Elena Radulescu, Ionela Andreea Neacsu, Alexandru-Mihai Grumezescu, Ecaterina Andronescu
Summary: In recent years, tissue engineering has focused on developing materials to improve osseointegration and biologic activity for bone replacements. Combining polymers and ceramics to meet complex requirements, especially to overcome the drawbacks of polymers, is seen as the optimal pathway to increase mechanical stability and mineralization. Ceramic materials, such as hydroxyapatite, obtained from natural sources are preferred for their bioactivity and similarity to native hydroxyapatite in human bone composition.
Article
Materials Science, Ceramics
Melike Nur Ozder, Fatih Ciftci, Ozge Rencuzogullari, Elif Damla Arisan, Cem Bulent Ustundag
Summary: This study investigates the properties of in situ synthesis of graphene oxide-hydroxyapatite (GO/HA) nanocomposite materials with different doping ratios for bone tissue support applications. The results show that scaffolds containing 0.5% and 1% GO (w/w) exhibit excellent cell proliferation and adhesion, making them promising materials for bone support applications.
CERAMICS INTERNATIONAL
(2023)
Article
Materials Science, Ceramics
Hossein Jodati, Aysen Tezcaner, Ammar Z. Alshemary, Volkan Sahin, Zafer Evis
Summary: Ion doping, specifically boron (B) doping, was used to modify the size, crystallinity, hardness, and biodegradability of hydroxyapatite (HA) nanoparticles in this study. The results showed that increasing B content led to reduced particle size, decreased crystallinity, and improved biodegradability and cell proliferation. However, high concentrations of B release did not have a positive effect on the osteogenic activity of cells.
CERAMICS INTERNATIONAL
(2022)
Article
Polymer Science
Mark-Jefferson Buer Boyetey, Selorm Torgbo, Prakit Sukyai
Summary: Bio-based biomaterials, such as bacterial cellulose (BC) and hydroxyapatite (HA), show promise for bone tissue engineering due to their renewable nature and bioactivity. This review discusses the biosynthesis and modification of BC, as well as the use of bioceramics like HA to enhance its properties. The application of growth factors and immobilization strategies are also explored for their potential in improving bioactivity. Additionally, the development of modern additive manufacturing techniques like 3D bioprinting holds great potential for tailor-made materials in tissue engineering.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Materials Science, Multidisciplinary
Amir Kahaie Khosrowshahi, Ali Baradar Khoshfetrat, Younes Beygi Khosrowshahi, Hossein Maleki-Ghaleh
Summary: The study found that a cobalt content of 1.25% in the Co-HA scaffold resulted in optimal osteogenic activity, while higher concentrations may lead to cytotoxic effects. Additionally, apatite growth was observed in the LCo-HA scaffold, and alkaline phosphatase activity and calcium deposition of osteoblastic cells cultured on the LCo-HA scaffold were in line with characterization and cytotoxicity results compared to the HA scaffold and control sample.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Engineering, Environmental
Laraib Abbas, Farzana Nazir, Asma Gulzar, Laiba Maryam, Asima Tayyeb, Mudassir Iqbal
Summary: This report elucidates the structure-activity relationship of nano-hydroxyapatite (nHA) and whitlockite (nWH) nanocomposites in bone tissue regeneration using Poly-Caprolactone (PCL) and Microcrystalline cellulose (MCC) composite. The study systematically evaluates the morphology, crystallinity, thermal properties, degradation, mechanical properties, and in vitro and in vivo biocompatibility of the composites. The findings suggest that the addition of nHA and nWH improves the crystallinity and mechanical strength of the composite and enhances its osteoconductivity and osteoinductivity.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2023)
Article
Chemistry, Medicinal
Bilal Aslam, Aleksandra Augustyniak, Susan A. Clarke, Helena Mcmahon
Summary: Bone tissue engineering is a promising treatment for bone loss. In this study, a tricomposite biomimetic scaffold consisting of chitosan, fucoidan, and hydroxyapatite (HA) was evaluated for its effects on the proliferation and differentiation of human mesenchymal stem cells (MSCs). The tricomposite scaffold had a uniform porous structure and promoted cell migration, proliferation, and vascularisation. HA and fucoidan increased cell mineralisation, while the tricomposite scaffold enhanced cell differentiation.
Article
Chemistry, Applied
Syrine Dimassi, Nicolas Tabary, Feng Chai, Cedric Zobrist, Jean-Christophe Hornez, Frederic Cazaux, Nicolas Blanchemain, Bernard Martel
Summary: This study investigates the influence of treatment time of electrospun chitosan nanofibers in dopamine bath on polydopamine coating and biomimetic deposition of hydroxyapatite. The scaffolds showed promising cytocompatibility and induced biomineralization in vitro, making them potential candidates for bone regeneration applications. Characterization by FTIR, SEM, XRD, and SEM-EDS confirmed the formation of apatitic phase particles on the surface of the scaffolds.
CARBOHYDRATE POLYMERS
(2022)
Article
Biochemistry & Molecular Biology
Nafiseh Jirofti, Maryam Hashemi, Ali Moradi, Fatemeh Kalalinia
Summary: This study developed a 3D printed crocin-loaded scaffold and demonstrated its good biocompatibility and mechanical properties through analysis of its structure, in vitro performance, and mechanical properties. It holds promise for applications in bone tissue engineering.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Ceramics
Mojtaba Mansoorianfar, Khashayar Shahin, Mariam Marlen Mirstrom, Dagang Li
Summary: This study developed a bioglass nanoparticle composite fabric with BG nanoparticles embedded between CNF layers. By enhancing osseoconductivity and increasing the Young's modulus of the fabric, it showed superior osteogenic potential and improved mechanical strength and structural stability.
CERAMICS INTERNATIONAL
(2021)
Article
Nanoscience & Nanotechnology
Mohan Wang, Zheyuan Gu, Beibei Li, Jingyi Zhang, Lu Yang, Xianyu Zheng, Faming Pan, Jiacai He
Summary: This study prepared and characterized chitosan-hydroxyapatite microsponges using a combination of microfluidic emulsion, freezing, and in situ thawing methods. The microsponges showed a porous structure and demonstrated good bioactivity and osteogenic differentiation potential. These microsponges have the potential to be used as bone substitute materials for bone tissue engineering.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Reza Barbaz-Isfahani, Saeed Saber-Samandari, Manouchehr Salehi
Summary: In this study, a novel method was used to synthesize microcapsules containing both epoxy and hardener healing agents in a single microcapsule. The microcapsule shell made of sodium alginate was enhanced with three types of nanoparticles. The addition of nanoparticles significantly improved the mechanical properties of microcapsule shells.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Materials Science, Composites
Reza Barbaz-Isfahani, Saeed Saber-Samandari, Manouchehr Salehi
Summary: This study investigates the effect of enhancing multicore microcapsules with various nanoparticles on the healing efficiency of microcapsule-based self-healing polymers. The results show that increasing the volume fraction of microcapsules can enhance the healing efficiency, while increasing the strength of microcapsules can decrease the healing efficiency.
JOURNAL OF REINFORCED PLASTICS AND COMPOSITES
(2023)
Article
Materials Science, Multidisciplinary
Huixing Liang, Maryam Sadat Mirinejad, Azadeh Asefnejad, Hadi Baharifar, Xiang Li, Saeed Saber-Samandari, Davood Toghraie, Amirsalar Khandan
Summary: Wound healing is a complex process that sometimes requires external stimuli. The use of biological agents in wound dressings can modify the healing process and promote better recovery. In this study, a bio-nanocomposite wound dressing containing different weight percentages of AgO-TiO2 nanoparticles was fabricated and characterized for its physical and chemical properties, as well as bioactivity and biodegradability.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Materials Science, Multidisciplinary
M. Mohammadzadeh Rad, S. Saber-Samandari, D. Olegovich Bokov, Wanich Suksatan, Mh Malekipour Esfahani, M. Y. P. M. Yusof, A. S. El-Shafay
Summary: In this study, nanocrystalline-Hydroxyapatite (n-HA) was combined with Polymethyl Methacrylate (PMMA) bone cement-Elastin (ELN) to produce a bone cement for orthopedic applications. The adaptability, weight loss, and pH change of the bone cement were evaluated using simulated body fluid (SBF) and phosphate-buffered saline (PBS). The morphology and microchemical analysis of the bone cement materials were examined using Field Emission Scanning Electron Microscopy (FE-SEM) and Energy-dispersive X-ray Spectroscopy (EDX). The mechanical properties, such as elastic modulus and impact strength, were measured using tensile test and Charpy impact test. The study found that the bone cement had low water absorption and porosity, and exhibited proper mechanical performance. This research is significant for the development of bone application materials.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Materials Science, Multidisciplinary
Huixing Liang, S. Niazi Angili, M. Morovvati, Xiang Li, S. Saber-Samandari, M. Y. P. M. Yusof, A. Khandan, D. Toghraie
Summary: The use of space holder method in the fabrication of composite scaffolds with calcium silicate bioceramic (Wollastonite) and titanium particles (TiO2-TiNP) has resulted in improved mechanical properties and potential biomedical applications.
MATERIALS SCIENCE AND ENGINEERING B-ADVANCED FUNCTIONAL SOLID-STATE MATERIALS
(2022)
Article
Electrochemistry
P. Bagheri, S. Saber-Samandari, A. Sadeghi, S. Akhtarian, A. Doostmohammadi
Summary: In this research, hydroxyapatite powder particles were coated on a Ti-6Al-4V alloy substrate using the plasma spraying method. The study aimed to take advantage of titanium's mechanical properties and hydroxyapatite's biological properties to create bone implants. Preheating the substrate was found to improve adhesion and reduce residual stress, however, it also resulted in the formation of an amorphous phase in the coating, leading to weaker mechanical properties.
TRANSACTIONS OF THE INSTITUTE OF METAL FINISHING
(2023)
Article
Engineering, Biomedical
Fatemeh Karami, Saeed Saber-Samandari
Summary: In this study, a multifunctional wound dressing based on carboxymethyl chitosan/sodium alginate hydrogel containing a nanostructured lipid carrier (NLC) was prepared. The dressing showed appropriate properties for absorbing exudates and maintaining wound moisture. It displayed excellent antibacterial activity and high biocompatibility, and had the ability to release the loaded drug slowly over a prolonged period of time. The results suggest that this novel nanocomposite could be a promising candidate as a wound dressing for treating various chronic wounds in skin tissues.
BIOMEDICAL MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Azin Rashidy Ahmady, Kavoos Razmjooee, Vida Nazar, Saeed Saber-Samandari
Summary: This study compared alginate microparticles and nanoparticles as thymol delivery systems. The results showed that thymol-loaded alginate nanoparticles released thymol in a more sustainable and controllable manner, and both carriers exhibited good cell viability and antibacterial properties.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Chemistry, Physical
Azin Rashidy Ahmady, Atefeh Solouk, Saeed Saber-Samandari, Somaye Akbari, Hadi Ghanbari, Bogumil E. Brycki
Summary: Nano-in-nano delivery technique is explored to address the limitations of most nanostructures used for drug delivery. This study investigated the release behavior of a novel nanoparticles-in-nanofibers delivery system composed of capsaicin-loaded alginate nanoparticles embedded in polycaprolactone-chitosan nanofiber mats. The results showed that embedding capsaicin-loaded alginate nanoparticles in polycaprolactone-chitosan nanofibers prolonged capsaicin release and effectively inhibited the proliferation of MCF-7 human breast cells.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Materials Science, Composites
Sina Shayanfar, Majid Nikkhah, Saeed Saber-Samandari, Manouchehr Salehi
Summary: This study aimed to investigate the behavior and failure resistance of composite materials, as well as the effect of nanoparticles on their flexural properties. Different weight percentages of nano-clay and nano-silica were added to a hybrid composite to analyze their effect. The addition of nanoparticles up to 1 wt.% improved flexural strength and modulus, and the samples containing nanoparticles were more resistant to damage growth.
JOURNAL OF COMPOSITE MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Saeed Saber-Samandari, Davood Toghraie
Summary: A new nanocomposite scaffold was successfully synthesized in this study, which exhibited high porosity and the ability to induce bone-like apatite formation by incorporating carbon nanotubes and montmorillonite nanoparticles in a gelatin network. After soaking in simulated body fluid for 14 days, the scaffold surface successfully deposited Ca2+, CO32-, and PO43- ions. In addition, the introduction of nanoparticles significantly improved the mechanical properties of the scaffold and reduced the enzymatic degradation rate. The scaffold showed good biocompatibility and high photothermal efficiency, making it suitable for tissue engineering applications.
MATERIALS SCIENCE AND ENGINEERING B-ADVANCED FUNCTIONAL SOLID-STATE MATERIALS
(2023)
Article
Multidisciplinary Sciences
Reza Barbaz-Isfahani, Hooman Dadras, Saeed Saber-Samandari, Alireza Taherzadeh-Fard, Gholamhossein Liaghat
Summary: This study investigates the effects of incorporating various types of nanoparticles, both singularly and in hybrid form, on the low-velocity impact (LVI) response of glass fiber reinforced polymer (GFRP) composites. The experimental results reveal that specimens with a single loading of MWCNT or nano-clay have a lower maximum contact force compared to pure specimens with fully rebounding behavior. Furthermore, incorporating more MWCNTs results in stiffer behavior and more brittleness.
Article
Materials Science, Composites
Maysam Alinia, Saeed Saber-Samandari, Seyyed Ali Sadough Vanini
Summary: The purpose of this study is to investigate the effects of adding nano-clay and nano-silica particles on the vibrational characteristics of composite cylindrical panels in corrosive environments. The study finds that adding nanoparticles can significantly improve the mechanical properties and natural frequencies of the composites, with nano-clay being more effective.
JOURNAL OF REINFORCED PLASTICS AND COMPOSITES
(2023)
Article
Materials Science, Multidisciplinary
Guoqi Guo, As'ad Alizadeh, Saeed Saber-Samandari, Maboud Hekmatifar, Jun Li, Mohammed Al-Bahrani, Navid Nasajpour-Esfahani, Mahmoud Shamsborhan, Davood Toghraie
Summary: Bullets are used as projectiles in firearms for various purposes. They also have industrial applications such as precision drilling, cutting, and shaping of hard materials. Different industries, such as automotive and aerospace, use fibers and fabrics with high toughness and tensile strength to resist impact and projectiles. In a recent study, the impact of external force on the strength of Kevlar nanofibers reinforced with silicon dioxide nanoparticles and ethylene glycol was investigated. The findings suggest that optimizing the external force is crucial for an effective collision process.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2023)
Article
Materials Science, Multidisciplinary
Farshad Rahmani, Reza Barbaz-Isfahani, Saeed Saber-Samandari, Manouchehr Salehi
Summary: The aim of this study is to investigate the critical buckling force of a sandwich structure with the addition of nanoparticles to composite faces in an acidic environment. The addition of 3 wt% nanoclay shows better performance in improving the durability of the structure against changes in the length and mass of the composite specimens. The immersion in 5% sulfuric acid for 30 days significantly reduces the critical buckling force of composite sandwiches.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)