Article
Chemistry, Analytical
Lucas Vinicius de Faria, Thalles Pedrosa Lisboa, Guilherme Figueira Alves, Maria Auxiliadora Costa Matos, Rodrigo Alejandro Abarza Munoz, Renato Camargo Matos
Summary: This study investigated the electrochemical response of chloramphenicol using modified electrodes and proposed a new analytical method. The results showed that the modified electrode exhibited advantages in sensitivity and reduction potential for chloramphenicol detection, indicating promising potential for monitoring chloramphenicol residues.
ANALYTICAL METHODS
(2021)
Article
Biophysics
Anabel Villalonga, Itziar Estabiel, Ana M. Perez-Calabuig, Beatriz Mayol, Concepcion Parrado, Reynaldo Villalonga
Summary: The novel amperometric aptasensor constructed for the specific detection of cardiac troponin I (cTnI) showed high sensitivity, specificity, and wide applicability for detecting the cardiac biomarker in a broad concentration range. It utilized a sandwich-type structure for detection and provided a detection limit of 0.6 pg/mL, along with high reproducibility and stability for quantifying cTnI in reconstituted human serum samples.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Analytical
Anderson M. Santos, Ademar Wong, Thiago M. Prado, Elson L. Fava, Orlando Fatibello-Filho, Maria D. P. T. Sotomayor, Fernando C. Moraes
Summary: A sensitive and selective method for ethinylestradiol detection was developed using a magnetic nanoparticle coated with molecularly imprinted polymers sensor, with significant increase in peak current magnitude observed. The sensor showed good repeatability and no interference from different compounds, with successful application in environmental and biological samples for ethinylestradiol detection, demonstrating recovery rates between 96 to 105% and 97-104%, respectively.
Article
Biochemical Research Methods
Lucas Vinicius de Faria, Davi Marques de Farias, Thalles Pedrosa Lisboa, Maria Auxiliadora Costa Matos, Rodrigo Alejandro Abarza Munoz, Renato Camargo Matos
Summary: The study utilized a batch injection analysis system with reduced graphene oxide as a modifier for the amperometric detection of levofloxacin and ciprofloxacin in pharmaceutical formulations, synthetic urine, and milk. The developed methods showed excellent analytical performance with high recovery rates and a minimum sample preparation requirement, making them suitable for routine analysis and quality control.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Edson R. Santana, Eduardo C. Martins, Almir Spinelli
Summary: A sensitive electroanalytical tool was developed for the detection of triclocarban by modifying a glassy carbon substrate with nitrogen-doped graphene quantum dots immobilized in chitosan, showing excellent oxidation current responses. The calibration plot for triclocarban in phosphate buffer solution ranged from 0.05 to 8.0 mu mol L-1, with detection and quantification limits of 17.0 and 57.0 nmol L-1, respectively. The modified electrode achieved accurate quantification of triclocarban in personal care products with recovery data ranging from 90 to 109%.
MICROCHEMICAL JOURNAL
(2021)
Article
Biochemistry & Molecular Biology
Liang Yan, Chaoyan Zhang, Fengna Xi
Summary: In this work, a portable and highly sensitive disposable electrochemical immunosensing platform was developed for the detection of prostate-specific antigen (PSA). The platform was based on a chitosan-graphene-modified indium tin oxide (ITO) electrode and showed high selectivity, reproducibility, and good storage stability.
Article
Engineering, Electrical & Electronic
Nesli Yagmurcukardes, Abdullah Bayram, Hasan Aydin, Mustafa Can, Serafettin Demic, Yaser Acikbas, Cem Celebi
Summary: In this study, the NH3 sensing capabilities of graphene films were improved by modifying self-assembled monolayers. The modified graphene films showed a two-fold increase in NH3 uptake compared to the unmodified films. This suggests that self-assembled monolayers can enhance NH3 adsorption and improve the detection response.
IEEE SENSORS JOURNAL
(2023)
Article
Electrochemistry
Sinan Mithat Muhammet
Summary: A sensitive and selective amperometric sensor for hydrogen peroxide was developed by mixing graphene oxide and alizarin red and coating it onto a glassy carbon electrode. The activated sensor exhibited high electrocatalytic activity and reversible redox ability, with high sensitivity and selectivity for hydrogen peroxide measurement.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Maria Pilo, Sylwia Baluta, Anna C. Loria, Gavino Sanna, Nadia Spano
Summary: This study presents a method for immobilizing glucose oxidase using an electrogenerated conducting film and enhancing the analytical performance of glucose detection by modifying it with graphene oxide. The biosensor with graphene oxide exhibited satisfactory values of linear dynamic range, limit of detection, and sensitivity.
Article
Spectroscopy
Xi-Qiong Mu, Dan Wang, Ling-Yu Meng, Yin-Quan Wang, Juan Chen
Summary: In this study, a novel fluorescent sensor based on glutathione-functionalized graphene quantum dots (GQDs@GSH) was developed to detect organophosphorus pesticide residues in Radix Angelica Sinensis. The sensor showed excellent sensitivity and accuracy through a fluorescence off-on-off-on mechanism, making it a promising tool for the detection of organophosphorus pesticide residues in traditional Chinese medicine and agricultural products.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Applied
Reena K. Sajwan, Pratima R. Solanki
Summary: A rapid and sensitive hybrid nanosensor using graphene quantum dots and gold nanoparticles was developed for detecting gentamicin in milk and egg samples. The nanosensor showed excellent recovery efficiency and can be used as a promising tool for speedy monitoring of food quantity.
Article
Chemistry, Analytical
Ming Pan, Peipei Guo, Haifeng Liu, Jiawei Lu, Qiubo Xie
Summary: This study developed a rapid detection method based on an electrochemical sensor, successfully detecting the residue of ciprofloxacin in food by modifying a carbon electrode with graphene oxide. Under optimal conditions, the method showed high linearity and stability, suitable for the analysis of CIP in milk samples.
JOURNAL OF ANALYTICAL SCIENCE AND TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Fatemeh Ershadian, Shahla Elhami
Summary: In this study, a carbon paste electrode was modified with a nanocomposite of reduced graphene oxide-graphene quantum dots-Fe3O4 for dopamine detection. The modified electrodes were characterized using field emission scanning electron microscopy-energy dispersive spectroscopy (FESEM/EDX) and transmission electron microscopy (TEM). Cyclic voltammetry results showed a significant increase in peak current for the modified electrode. The efficiency of the modified electrode for dopamine determination was examined using cyclic voltammetry and differential pulse voltammetry methods, showing a linear relationship between dopamine concentration and peak current.
Article
Agriculture, Multidisciplinary
Raquel G. Rocha, Lucas V. de Faria, Vanessa F. Silva, Rodrigo A. A. Munoz, Eduardo M. Richter
Summary: A low-cost and portable electrochemical method for detecting sulfanilamide residues in honey was developed using a 3D-printed disposable device. The method demonstrated linear concentration ranges, a low detection limit, and suitable RSD values, and it was selective for sulfanilamide in honey samples. The results obtained by the proposed method were statistically similar to those obtained by HPLC, indicating the accuracy and absence of matrix interference in the analysis.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Review
Chemistry, Analytical
Preeyaporn Reanpang, Pijika Mool-am-kha, Jantima Upan, Jaroon Jakmunee
Summary: A simple, rapid, and cost-effective flow injection amperometric sensor was developed for sensitive determination of uric acid, utilizing a new combination of carbon black and graphene oxide modified screen-printed carbon electrode. The modified electrode showed enhanced sensitivity, stability, and automation for uric acid detection. The system achieved good selectivity, repeatability, and stability, with a detection limit of 0.01 µM and a throughput of 25 injections per hour.
Review
Chemistry, Analytical
Carlos Adelantado, Mohammed Zougagh, Angel Rios
Summary: This paper presents an overview of the increasing role of capillary electrophoresis in the characterization and direct analysis of nanomaterials. Capillary electrophoretic approaches have been shown to be highly relevant and useful in the analysis of nonmetallic, metal, metal oxide nanoparticles, and quantum dots, with the potential to increase selectivity and sensitivity. By optimizing parameters, nanomaterials can be identified based on their size, shape, or associations with binding agents. The quickness and usefulness of capillary electrophoresis in quantifying or screening ultra-small particles make it an excellent technique for the analysis of synthesized nanostructures in research or routine laboratories.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Book Review
Biochemical Research Methods
Angel Rios
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Manuel Bartolome, Ana M. Contento, Maria J. Villasenor, Angel Rios
Summary: The study developed a quick and highly sensitive plasmonic sensor for the qualitative and quantitative assessment of all proteinogenic amino acids in nutritional supplements using citrate coated gold nanoparticles as an optical probe. The sensor allowed for both simple visual screening and quantitative confirmation of amino acid content.
Article
Obstetrics & Gynecology
Angel R. Gonzalez Rios, Israel Zighelboim, James Anasti, Joseph Merola, Jill Stoltzfus, Vincent Lucente
Summary: The objective of this study was to evaluate factors associated with obstetric anal sphincter injury and identify modifiable risks. The study found that episiotomy and operative delivery were modifiable risks, and even a short second stage of labor was associated with a significant risk of injury.
FEMALE PELVIC MEDICINE AND RECONSTRUCTIVE SURGERY
(2022)
Article
Biochemistry & Molecular Biology
Marwa Louleb, Ismael Galvan, Latifa Latrous, Nicholas M. Justyn, Geoffrey E. Hill, Angel Rios, Mohammed Zougagh
Summary: Unlike humans, some animals have the ability to deposit porphyrins in their skin and hair. In this study, we developed a simple and efficient analytical method for quantifying porphyrins in the hair of the Southern flying squirrel. This method offers higher simplicity, precision, selectivity, and sensitivity compared to previous methods, and has the potential to become the standard technique for porphyrin analysis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Yassine Benmassaoud, Khaled Murtada, Rachid Salghi, Mohammed Zougagh, Angel Rios
Summary: A rapid and sensitive technique for fraud determination in vanilla flavors was developed using liquid chromatography and electrochemical detection. The method successfully determined six phenolic compounds in vanilla flavors, with high sensitivity and good selectivity, making it suitable for analyzing these compounds in vanilla extract products.
Article
Chemistry, Analytical
Cristina Montes, M. Laura Soriano, M. Jesus Villasenor, Angel Rios
Summary: This study focuses on the characterization and discrimination between free quercetin and quercetin-loaded nanoemulsions (Q-NEs), and the design of a plasmonic metal liquid platform for their quantification. Reproducible synthesis of Q-NEs was achieved using Generally Recognized as Safe (GRAS) components and a low-energy method. The developed plasmonic sensing platform based on tuned gold nanorods-bone shaped structure allowed for the quantification of Q-NEs without altering their native nanostructure. The platform showed good analytical performance characteristics and was validated against commercial nutritional supplements.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Engineering, Environmental
Elena Brinas, Viviana Jehova Gonzalez, Maria Antonia Herrero, Mohammed Zougagh, Angel Rios, Ester Vazquez
Summary: A simple, reproducible, and sensitive method using surface-enhanced Raman spectroscopy (SERS) was developed for the detection of graphene oxide (GO) in water samples at low concentrations. The practical limit of quantification achieved with this method was 0.1 ng mL(-1), which is lower than the predicted concentrations for graphene in effluent water. This optimized procedure has been successfully applied to the determination of ultratraces of GO in water samples.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Chemistry, Applied
Esther Pinilla-Penalver, Beatriz Garcia-Bejar, Ana M. Contento, Angel Rios
Summary: This study investigates the adsorption of resveratrol on graphene quantum dots (GQDs) and its impact on photostability and antioxidant capacity. The results show that GQDs can effectively inhibit the isomerization of resveratrol and enhance its antioxidant properties. The photoprotective effect of GQDs on resveratrol is also demonstrated in food samples.
Article
Chemistry, Analytical
Pablo Montoro-Leal, Mohammed Zougagh, Antonio Sanchez-Ruiz, Angel Rios, Elisa Vereda Alonso
Summary: A modified screen-printed carbon electrode was designed for the determination of malondialdehyde (MDA), an important biomarker of oxidative stress. A novel hybrid nanomaterial (MGO@MIPy) was synthesized by coating magnetic graphene oxide (MGO) with a molecularly imprinted polypyrrole (MIPy). The nanocomposite exhibited magnetic properties for separation and manipulation of analyte, and the electroactive molecule MDA-DAN was used as a template for synthesis. The developed electrochemical sensor demonstrated excellent analytical performance for the routine monitoring of MDA in serum samples.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Cristina Montes, Natalia Villamayor, M. Jesus Villasenor, Angel Rios
Summary: A selective and sensitive fluorescent nanoprobe (S,N-GQDs) was designed for detection and discrimination between free and quercetin-loaded nanoemulsion in food samples. The method showed high sensitivity, a wide linear dynamic range, and accurate discrimination between different forms of quercetin.
ANALYTICA CHIMICA ACTA
(2022)
Editorial Material
Biochemical Research Methods
Angel Rios, Wolfgang J. Parak
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Francesca Ferraris, Carlos Adelantado, Andrea Raggi, Sara Savini, Mohammed Zougagh, Angel Rios, Francesco Cubadda
Summary: A method using ICP-MS and microwave-assisted acid digestion was developed for the determination of total titanium in food and food supplements. The method was successfully validated and enables rapid screening of food samples for the presence of TiO2 particles.
Article
Chemistry, Multidisciplinary
Esther Pinilla-Penalver, Adrian Esteban-Arranz, Ana M. Contento, Angel Rios
Summary: A novel fluorescent sensor based on the competitive interactions between riboflavin, catechin, and graphene oxide (GO) has been proposed in this study. The sensor shows sensitivity and selectivity, making it suitable for environmental analysis control and determination of catechin in food samples.