标题
Architecture and hydration of the arginine-binding site of neuropilin-1
作者
关键词
-
出版物
FEBS Journal
Volume 285, Issue 7, Pages 1290-1304
出版商
Wiley
发表日期
2018-02-12
DOI
10.1111/febs.14405
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- NRPa-308, a new neuropilin-1 antagonist, exerts in vitro anti-angiogenic and anti-proliferative effects and in vivo anti-cancer effects in a mouse xenograft model
- (2018) Wang-Qing Liu et al. CANCER LETTERS
- Conformational latitude - activity relationship of KPPR tetrapeptide analogues toward their ability to inhibit binding of vascular endothelial growth factor 165 to neuropilin-1
- (2017) Bartlomiej Fedorczyk et al. JOURNAL OF PEPTIDE SCIENCE
- Structure-activity relationship study of tetrapeptide inhibitors of the Vascular Endothelial Growth Factor A binding to Neuropilin-1
- (2017) Dagmara Tymecka et al. PEPTIDES
- Carbohydrate-based peptidomimetics targeting neuropilin-1: Synthesis, molecular docking study and in vitro biological activities
- (2016) Mylène Richard et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Ablation of Neuropilin 1 from glioma-associated microglia and macrophages slows tumor progression
- (2016) Jeremy T. Miyauchi et al. Oncotarget
- Immunoglobulin Fc-fused, neuropilin-1-specific peptide shows efficient tumor tissue penetration and inhibits tumor growth via anti-angiogenesis
- (2015) Ye-Jin Kim et al. JOURNAL OF CONTROLLED RELEASE
- Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity
- (2015) Gerald J Prud'homme et al. Oncotarget
- Discovery of novel inhibitors of vascular endothelial growth factor-A–Neuropilin-1 interaction by structure-based virtual screening
- (2014) Anna Starzec et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Structure-based discovery of a small non-peptidic Neuropilins antagonist exerting in vitro and in vivo anti-tumor activity on breast cancer model
- (2014) Lucia Borriello et al. CANCER LETTERS
- N-Terminal Modification of VEGF-A C Terminus-Derived Peptides Delineates Structural Features Involved in Neuropilin-1 Binding and Functional Activity
- (2014) Haiyan Jia et al. CHEMBIOCHEM
- Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis
- (2014) A. Fantin et al. DEVELOPMENT
- Design of a Cyclotide Antagonist of Neuropilin-1 and -2 That Potently Inhibits Endothelial Cell Migration
- (2013) Jennifer A. Getz et al. ACS Chemical Biology
- Hydration Properties of Ligands and Drugs in Protein Binding Sites: Tightly-Bound, Bridging Water Molecules and Their Effects and Consequences on Molecular Design Strategies
- (2013) Alfonso T. García-Sosa Journal of Chemical Information and Modeling
- Stability and function of regulatory T cells is maintained by a neuropilin-1–semaphorin-4a axis
- (2013) Greg M. Delgoffe et al. NATURE
- Neuropilin 1 guides regulatory T cells into VEGF-producing melanoma
- (2013) Wiebke Hansen OncoImmunology
- Structural Basis for Selective Vascular Endothelial Growth Factor-A (VEGF-A) Binding to Neuropilin-1
- (2012) Matthew W. Parker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rapid and Accurate Prediction and Scoring of Water Molecules in Protein Binding Sites
- (2012) Gregory A. Ross et al. PLoS One
- REFMAC5 for the refinement of macromolecular crystal structures
- (2011) Garib N. Murshudov et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Overview of theCCP4 suite and current developments
- (2011) Martyn D. Winn et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Neuropilins are positive regulators of Hedgehog signal transduction
- (2011) R. T. Hillman et al. GENES & DEVELOPMENT
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Sugar-based peptidomimetics as potential inhibitors of the vascular endothelium growth factor binding to neuropilin-1
- (2010) Alexandre Novoa et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity
- (2010) H Jia et al. BRITISH JOURNAL OF CANCER
- Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-β signaling in hepatic stellate cells
- (2010) Sheng Cao et al. JOURNAL OF CLINICAL INVESTIGATION
- Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction
- (2010) Ashley Jarvis et al. JOURNAL OF MEDICINAL CHEMISTRY
- Calculation of Local Water Densities in Biological Systems: A Comparison of Molecular Dynamics Simulations and the 3D-RISM-KH Molecular Theory of Solvation
- (2010) Martin C. Stumpe et al. JOURNAL OF PHYSICAL CHEMISTRY B
- xia2: an expert system for macromolecular crystallography data reduction
- (2009) G. Winter JOURNAL OF APPLIED CRYSTALLOGRAPHY
- Energetics of Displacing Water Molecules from Protein Binding Sites: Consequences for Ligand Optimization
- (2009) Julien Michel et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration
- (2009) T. Teesalu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neuropilins: structure, function and role in disease
- (2008) Caroline Pellet-Many et al. BIOCHEMICAL JOURNAL
- Neuropilin-1 is a receptor for transforming growth factor β-1, activates its latent form, and promotes regulatory T cell activity
- (2008) Yelena Glinka et al. JOURNAL OF LEUKOCYTE BIOLOGY
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