Exploring oxidative modifications of tyrosine: An update on mechanisms of formation, advances in analysis and biological consequences

Oxidative Post-Translational Modifications Develop LONP1 Dysfunction in Pressure Overload Heart Failure

(2014) Atsushi Hoshino et al.   Circulation-Heart Failure

Thiol Peroxidase Deficiency Leads to Increased Mutational Load and Decreased Fitness in Saccharomyces cerevisiae

(2014) A. Kaya et al.   GENETICS

Structural and Molecular Basis of the Peroxynitrite-mediated Nitration and Inactivation ofTrypanosoma cruziIron-Superoxide Dismutases (Fe-SODs) A and B

(2014) Alejandra Martinez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Emerging Immunological Role of Post-Translational Modifications by Reactive Nitrogen Species in Cancer Microenvironment

(2014) Francesco De Sanctis et al.   Frontiers in Immunology

Reversible, Long-Range Radical Transfer in E. coli Class Ia Ribonucleotide Reductase

(2013) Ellen C. Minnihan et al.   ACCOUNTS OF CHEMICAL RESEARCH

Oxidation and nitration of α-synuclein and their implications in neurodegenerative diseases

(2013) Cecilia Chavarría et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Formation of a tyrosine adduct involved in lignin degradation byTrametopsis cervinalignin peroxidase: a novel peroxidase activation mechanism

(2013) Yuta Miki et al.   BIOCHEMICAL JOURNAL

The Role of Cysteine Proteinases and their Inhibitors in the Host-Pathogen Cross Talk

(2013) Natasa Kopitar-Jerala   CURRENT PROTEIN & PEPTIDE SCIENCE

Oxidative damage and cellular defense mechanisms in sea urchin models of aging

(2013) Colin Du et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reporter ion-based mass spectrometry approaches for the detection of non-enzymatic protein modifications in biological samples

(2013) Karina Tveen-Jensen et al.   Journal of Proteomics

The use of the methods of radiolysis to explore the mechanisms of free radical modifications in proteins

(2013) Chantal Houée-Levin et al.   Journal of Proteomics

Oxidative stress and mitochondrial protein quality control in aging

(2013) Eirini Lionaki et al.   Journal of Proteomics

Mass spectrometry analysis of nitrotyrosine-containing proteins

(2013) Xianquan Zhan et al.   MASS SPECTROMETRY REVIEWS

Pituitary Adenoma Nitroproteomics: Current Status and Perspectives

(2013) Xianquan Zhan et al.   Oxidative Medicine and Cellular Longevity

Obstructive Sleep Apnea and Diabetic Neuropathy

(2012) Abd A. Tahrani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ubiquitin and Proteasomes in Transcription

(2012) Fuqiang Geng et al.   Annual Review of Biochemistry

Tyrosine Modifications in Aging

(2012) Maria B. Feeney et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Active Thiol Sensors of Oxidative and Nitrosative Stress

(2012) Andrés Vázquez-Torres   ANTIOXIDANTS & REDOX SIGNALING

Molecular basis of intramolecular electron transfer in proteins during radical-mediated oxidations: Computer simulation studies in model tyrosine–cysteine peptides in solution

(2012) Ariel A. Petruk et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Redox signalling via the cellular thiolstat

(2012) Claus Jacob   BIOCHEMICAL SOCIETY TRANSACTIONS

FTIR spectroscopy of the reaction center of Chloroflexus aurantiacus: Photooxidation of the primary electron donor

(2012) A. A. Zabelin et al.   BIOCHEMISTRY-MOSCOW

Cooperation between proteolytic systems in cardiomyocyte recycling

(2012) O. Yamaguchi et al.   CARDIOVASCULAR RESEARCH

Immunoglobulins Against Tyrosine-Nitrated Epitopes in Coronary Artery Disease

(2012) Leonor Thomson et al.   CIRCULATION

Reactivity of chlorine dioxide with amino acids, peptides, and proteins

(2012) Virender K. Sharma et al.   Environmental Chemistry Letters

Fast repair of protein radicals by urate

(2012) Anastasia S. Domazou et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fluorogenic tagging of protein 3-nitrotyrosine with 4-(aminomethyl)benzene sulfonate in tissues: A useful alternative to Immunohistochemistry for fluorescence microscopy imaging of protein nitration

(2012) V.S. Sharov et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protein S-nitrosylation: What's going on in plants?

(2012) Jéremy Astier et al.   FREE RADICAL BIOLOGY AND MEDICINE

Kinetics of oxidation of tyrosine by a model alkoxyl radical

(2012) Lisa K. Folkes et al.   FREE RADICAL RESEARCH

Role of the Tyr-Cys Cross-link to the Active Site Properties of Galactose Oxidase

(2012) Dalia Rokhsana et al.   INORGANIC CHEMISTRY

Proton-Coupled Electron Transfer and Redox-Active Tyrosines: Structure and Function of the Tyrosyl Radicals in Ribonucleotide Reductase and Photosystem II

(2012) Bridgette A. Barry et al.   Journal of Physical Chemistry Letters

Selective tau tyrosine nitration in non-AD tauopathies

(2011) Juan F. Reyes et al.   ACTA NEUROPATHOLOGICA

Tyrosine Nitration within the Proline-Rich Region of Tau in Alzheimer's Disease

(2011) Juan F. Reyes et al.   AMERICAN JOURNAL OF PATHOLOGY

A methodology for simultaneous fluorogenic derivatization and boronate affinity enrichment of 3-nitrotyrosine-containing peptides

(2011) Elena S. Dremina et al.   ANALYTICAL BIOCHEMISTRY

Electron Transfer in Peptides: The Influence of Charged Amino Acids

(2011) Jian Gao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Peroxynitrite-Induced Nitrative and Oxidative Modifications Alter Tau Filament Formation

(2011) Laurel Vana et al.   BIOCHEMISTRY

Nitration of tyrosines 46 and 48 induces the specific degradation of cytochrome c upon change of the heme iron state to high-spin

(2011) Irene Díaz-Moreno et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Kinetics of 3-Chlorotyrosine Formation and Loss due to Hypochlorous Acid and Chloramines

(2011) Matthew P. Curtis et al.   CHEMICAL RESEARCH IN TOXICOLOGY

A copper–hydrogen peroxide redox system induces dityrosine cross-links and chemokine oligomerisation

(2011) Helen J. MacGregor et al.   CYTOKINE

Smoking, COPD, and 3-Nitrotyrosine Levels of Plasma Proteins

(2011) Hongjun Jin et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Cardiac calcium pump inactivation and nitrosylation in senescent rat myocardium are not attenuated by long-term treadmill training

(2011) Melissa M. Thomas et al.   EXPERIMENTAL GERONTOLOGY

Vascular peroxidase-1 is rapidly secreted, circulates in plasma, and supports dityrosine cross-linking reactions

(2011) Guangjie Cheng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Peroxidase catalysed cross-linking of an intrinsically unstructured protein via dityrosine bonds in the oocyst wall of the apicomplexan parasite, Eimeria maxima

(2011) Kelly Mai et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

In vivo protein tyrosine nitration in Arabidopsis thaliana

(2011) Jorge Lozano-Juste et al.   JOURNAL OF EXPERIMENTAL BOTANY

Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells

(2011) Barbara Molon et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The free amino acid tyrosine enhances the chlorinating activity of human myeloperoxidase

(2011) Irina I. Vlasova et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Epitope motif of an anti-nitrotyrosine antibody specific for tyrosine-nitrated peptides revealed by a combination of affinity approaches and mass spectrometry

(2011) Mihaela Drǎguşanu et al.   JOURNAL OF PEPTIDE SCIENCE

Confident identification of 3-nitrotyrosine modifications in mass spectral data across multiple mass spectrometry platforms

(2011) Bensheng Li et al.   Journal of Proteomics

Selective Chemoprecipitation and Subsequent Release of Tagged Species for the Analysis of Nitropeptides by Liquid Chromatography–Tandem Mass Spectrometry

(2011) Katalin Prokai-Tatrai et al.   MOLECULAR & CELLULAR PROTEOMICS

Photo-oxidation of proteins

(2011) David I. Pattison et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Loss of CD4 T-cell-dependent tolerance to proteins with modified amino acids

(2011) V. Gauba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A stringent approach to improve the quality of nitrotyrosine peptide identifications

(2011) Bart Ghesquière et al.   PROTEOMICS

Oxidative protein damage and the proteasome

(2010) S. Grimm et al.   AMINO ACIDS

Protein oxidation: role in signalling and detection by mass spectrometry

(2010) Corinne M. Spickett et al.   AMINO ACIDS

Top-Down Mass Analysis of Protein Tyrosine Nitration: Comparison of Electron Capture Dissociation with “Slow-Heating” Tandem Mass Spectrometry Methods

(2010) Victor A. Mikhailov et al.   ANALYTICAL CHEMISTRY

Selective Enrichment and Mass Spectrometric Identification of Nitrated Peptides Using Fluorinated Carbon Tags

(2010) Jae Kyung Kim et al.   ANALYTICAL CHEMISTRY

Intramolecular Electron Transfer in the Photooxidized Peptides Tyrosine-Histidine and Histidine-Tyrosine: A Time-Resolved CIDNP Study

(2010) Olga B. Morozova et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Redox Control Systems in the Nucleus: Mechanisms and Functions

(2010) Young-Mi Go et al.   ANTIOXIDANTS & REDOX SIGNALING

Kinetics of reduction of tyrosine phenoxyl radicals by glutathione

(2010) Lisa K. Folkes et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Mitochondrial Complex I Activity and Oxidative Damage to Mitochondrial Proteins in the Prefrontal Cortex of Patients With Bipolar Disorder

(2010) Ana C. Andreazza et al.   ARCHIVES OF GENERAL PSYCHIATRY

Efficient Identification and Quantification of Peptides Containing Nitrotyrosine by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry after Derivatization

(2010) Hiroki Tsumoto et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Myeloperoxidase: An Oxidative Pathway for Generating Dysfunctional High-Density Lipoprotein

(2010) Baohai Shao et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Lipid Peroxyl Radicals Mediate Tyrosine Dimerization and Nitration in Membranes

(2010) Silvina Bartesaghi et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Myeloperoxidase-antineutrophil cytoplasmic antibody-associated crescentic glomerulonephritis with rheumatoid arthritis: a comparison of patients without rheumatoid arthritis

(2010) Noriaki Kurita et al.   Clinical and Experimental Nephrology

Targeting the redox regulation of SERCA in vascular physiology and disease

(2010) XiaoYong Tong et al.   CURRENT OPINION IN PHARMACOLOGY

New Therapeutic and Biomarker Discovery for Peripheral Diabetic Neuropathy: PARP Inhibitor, Nitrotyrosine, and Tumor Necrosis Factor-α

(2010) Viktor R. Drel et al.   ENDOCRINOLOGY

Neutrophil-mediated oxidation of enkephalins via myeloperoxidase-dependent addition of superoxide

(2010) Péter Nagy et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactions of superoxide with the myoglobin tyrosyl radical

(2010) Andrew B. Das et al.   FREE RADICAL BIOLOGY AND MEDICINE

Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome

(2010) Michelle Gracanin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention

(2010) Michael J. Davies   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Natural IgM Antibodies Against Oxidation-Specific Epitopes

(2010) Christoph J. Binder   JOURNAL OF CLINICAL IMMUNOLOGY

The First Global Screening of Protein Substrates Bearing Protein-Bound 3,4-Dihydroxyphenylalanine inEscherichia coliand Human Mitochondria

(2010) Sangkyu Lee et al.   JOURNAL OF PROTEOME RESEARCH

Tyrosine−Lipid Peroxide Adducts from Radical Termination: Para Coupling and Intramolecular Diels−Alder Cyclization

(2010) Roman Shchepin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Endogenous 3,4-Dihydroxyphenylalanine and Dopaquinone Modifications on Protein Tyrosine

(2010) Xu Zhang et al.   MOLECULAR & CELLULAR PROTEOMICS

Nitration of the Egg-Allergen Ovalbumin Enhances Protein Allergenicity but Reduces the Risk for Oral Sensitization in a Murine Model of Food Allergy

(2010) Eva Untersmayr et al.   PLoS One

Chemical Biology of Peroxynitrite: Kinetics, Diffusion, and Radicals

(2009) Gerardo Ferrer-Sueta et al.   ACS Chemical Biology

Chemical Approach for Specific Enrichment and Mass Analysis of Nitrated Peptides

(2009) Jung Rok Lee et al.   ANALYTICAL CHEMISTRY

Electron Transfer in Peptides with Cysteine and Methionine as Relay Amino Acids

(2009) Min Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nitroproteomics of Peripheral Blood Mononuclear Cells from Patients and a Rat Model of ALS

(2009) Giovanni Nardo et al.   ANTIOXIDANTS & REDOX SIGNALING

Mechanisms of Peroxynitrite-Mediated Nitration of Tyrosine

(2009) Hakan Gunaydin et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Autophagy: links with the proteasome

(2009) Trond Lamark et al.   CURRENT OPINION IN CELL BIOLOGY

Efficient repair of protein radicals by ascorbate

(2009) Anastasia S. Domazou et al.   FREE RADICAL BIOLOGY AND MEDICINE

Superoxide-mediated Formation of Tyrosine Hydroperoxides and Methionine Sulfoxide in Peptides through Radical Addition and Intramolecular Oxygen Transfer

(2009) Péter Nagy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Preparation and Characterization of a Polyclonal Antibody against Brominated Protein

(2009) Yasuhiro Kambayashi et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Efficiency of methemoglobin, hemin and ferric citrate in catalyzing protein tyrosine nitration, protein oxidation and lipid peroxidation in a bovine serum albumin–liposome system: Influence of pH

(2009) Pingzhang Gao et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Electron Relay Race in Peptides

(2009) Bernd Giese et al.   JOURNAL OF ORGANIC CHEMISTRY

Protein Tyrosine Nitration: Selectivity, Physicochemical and Biological Consequences, Denitration, and Proteomics Methods for the Identification of Tyrosine-Nitrated Proteins

(2009) Nicolas Abello et al.   JOURNAL OF PROTEOME RESEARCH

Electron capture dissociation mass spectrometry of tyrosine nitrated peptides

(2009) Andrew W. Jones et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

In Vitroandin VivoProtein-bound Tyrosine Nitration Characterized by Diagonal Chromatography

(2009) Bart Ghesquière et al.   MOLECULAR & CELLULAR PROTEOMICS

The proteasomal system

(2009) Tobias Jung et al.   MOLECULAR ASPECTS OF MEDICINE

Characterization of Detergent-Insoluble Proteins in ALS Indicates a Causal Link between Nitrative Stress and Aggregation in Pathogenesis

(2009) Manuela Basso et al.   PLoS One

PTMap—A sequence alignment software for unrestricted, accurate, and full-spectrum identification of post-translational modification sites

(2009) Yue Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of novel mass spectrometric methods for identifying HOCl-induced modifications to proteins

(2009) Laetitia Mouls et al.   PROTEOMICS

Quantitative identification of protein nitration sites

(2009) Giovanni Chiappetta et al.   PROTEOMICS

Impact of Peroxynitrite Modification on Structure and Immunogenicity of H2A Histone

(2009) M. A. Khan et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Chemical labeling and enrichment of nitrotyrosine-containing peptides

(2009) Nicolas Abello et al.   TALANTA

Influence of Amino Acid Side Chains on Long-Distance Electron Transfer in Peptides: Electron Hopping via “Stepping Stones”

(2008) Meike Cordes et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mammalian Heme Peroxidases: From Molecular Mechanisms to Health Implications

(2008) Michael J. Davies et al.   ANTIOXIDANTS & REDOX SIGNALING

The effect of neighboring methionine residue on tyrosine nitration and oxidation in peptides treated with MPO, H 2 O 2 , and NO 2 − or peroxynitrite and bicarbonate: Role of intramolecular electron transfer mechanism?

(2008) Hao Zhang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Protein tyrosine nitration—An update

(2008) Harry Ischiropoulos   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Kinetics of Tyrosyl Radical Reduction by Selenocysteine

(2008) Daniel Steinmann et al.   BIOCHEMISTRY

Cross-Link Formation of the Cysteine 228−Tyrosine 272 Catalytic Cofactor of Galactose Oxidase Does Not Require Dioxygen†‡

(2008) Melanie S. Rogers et al.   BIOCHEMISTRY

The role of TyrD in the electron transfer kinetics in Photosystem II

(2008) Malwina Szczepaniak et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Proteomic analysis of protein tyrosine nitration after ischemia reperfusion injury: Mitochondria as the major target

(2008) Bin Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Denitration of L-type calcium channel

(2008) Minho Kang et al.   FEBS LETTERS

Chlorine dioxide reaction with selected amino acids in water

(2008) Sergio Navalon et al.   JOURNAL OF HAZARDOUS MATERIALS

Proteomic identification of nitrated brain proteins in traumatic brain-injured rats treated postinjury with gamma-glutamylcysteine ethyl ester: Insights into the role of elevation of glutathione as a potential therapeutic strategy for traumatic brain injury

(2008) Tanea T. Reed et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Direct Observation of NH2•Reactions with Oxygen, Amino Acids, and Melanins

(2008) K. Clarke et al.   JOURNAL OF PHYSICAL CHEMISTRY A

The Carbonate Radical: Its Reactivity with Oxygen, Ammonia, Amino Acids, and Melanins

(2008) K. Clarke et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Factors That Contribute to the Misidentification of Tyrosine Nitration by Shotgun Proteomics

(2008) Stanley M. Stevens et al.   MOLECULAR & CELLULAR PROTEOMICS

Peptizer, a Tool for Assessing False Positive Peptide Identifications and Manually Validating Selected Results

(2008) Kenny Helsens et al.   MOLECULAR & CELLULAR PROTEOMICS

Nitrotyrosine-modified SERCA2: a cellular sensor of reactive nitrogen species

(2008) Diana J. Bigelow   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Raman, IR, UV–vis and EPR characterization of two copper dioxolene complexes derived from L-dopa and dopamine

(2008) Wagner J. Barreto et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

H2O2/Nitrite-Induced Post-translational Modifications of Human Hemoglobin Determined by Mass Spectrometry: Redox Regulation of Tyrosine Nitration and 3-Nitrotyrosine Reduction by Antioxidants

(2007) Hauh-Jyun Candy Chen et al.   CHEMBIOCHEM

Effect ofortho-SR Groups on O−H Bond Strength and H-Atom Donating Ability of Phenols:  A Possible Role for the Tyr-Cys Link in Galactose Oxidase Active Site?

(2007) Riccardo Amorati et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY