标题
Hidden features: exploring the non-canonical functions of metabolic enzymes
作者
关键词
-
出版物
Disease Models & Mechanisms
Volume 11, Issue 8, Pages dmm033365
出版商
The Company of Biologists
发表日期
2018-07-06
DOI
10.1242/dmm.033365
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy
- (2017) Xinjian Li et al. MOLECULAR CELL
- Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination
- (2017) Sharanya Sivanand et al. MOLECULAR CELL
- Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory
- (2017) Philipp Mews et al. NATURE
- Decreased Expression of Fructose-1,6-bisphosphatase Associates with Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma
- (2016) H. Hirata et al. CANCER RESEARCH
- Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton
- (2016) Hai Hu et al. CELL
- PKM2, cancer metabolism, and the road ahead
- (2016) Talya L Dayton et al. EMBO REPORTS
- Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma
- (2016) Talya L. Dayton et al. GENES & DEVELOPMENT
- Non-metabolic functions of glycolytic enzymes in tumorigenesis
- (2016) X Yu et al. ONCOGENE
- Metabolic Enzymes Moonlighting in the Nucleus: Metabolic Regulation of Gene Transcription
- (2016) Aristeidis E. Boukouris et al. TRENDS IN BIOCHEMICAL SCIENCES
- PKM2 and cancer: The function of PKM2 beyond glycolysis
- (2016) GAOCHAO DONG et al. Oncology Letters
- ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch
- (2016) Steven Zhao et al. Cell Reports
- Aerobic glycolysis tunes YAP/TAZ transcriptional activity
- (2015) E. Enzo et al. EMBO JOURNAL
- Increased Expression of the Autocrine Motility Factor is Associated With Poor Prognosis in Patients With Clear Cell–Renal Cell Carcinoma
- (2015) Giuseppe Lucarelli et al. MEDICINE
- Serine and SAM Responsive Complex SESAME Regulates Histone Modification Crosstalk by Sensing Cellular Metabolism
- (2015) Shanshan Li et al. MOLECULAR CELL
- Pyruvate Kinase Isoform Expression Alters Nucleotide Synthesis to Impact Cell Proliferation
- (2015) Sophia Y. Lunt et al. MOLECULAR CELL
- Lack of Evidence for PKM2 Protein Kinase Activity
- (2015) Aaron M. Hosios et al. MOLECULAR CELL
- Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation
- (2015) Yuhui Jiang et al. NATURE CELL BIOLOGY
- Joined at the hip: kinetochores, microtubules, and spindle assembly checkpoint signaling
- (2015) Carlos Sacristan et al. TRENDS IN CELL BIOLOGY
- The Acetate/ACSS2 Switch Regulates HIF-2 Stress Signaling in the Tumor Cell Microenvironment
- (2015) Rui Chen et al. PLoS One
- Nuclear lactate dehydrogenase modulates histone modification in human hepatocytes
- (2014) Zachary Castonguay et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Fructose bisphosphate aldolase is involved in the control of RNA polymerase III-directed transcription
- (2014) Małgorzata Cieśla et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Targeting ABL1-Mediated Oxidative Stress Adaptation in Fumarate Hydratase-Deficient Cancer
- (2014) Carole Sourbier et al. CANCER CELL
- A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation
- (2014) Gopinath Sutendra et al. CELL
- Akt-Dependent Metabolic Reprogramming Regulates Tumor Cell Histone Acetylation
- (2014) Joyce V. Lee et al. Cell Metabolism
- SAICAR Induces Protein Kinase Activity of PKM2 that Is Necessary for Sustained Proliferative Signaling of Cancer Cells
- (2014) Kirstie E. Keller et al. MOLECULAR CELL
- Fructose-1,6-bisphosphatase opposes renal carcinoma progression
- (2014) Bo Li et al. NATURE
- An acetate switch regulates stress erythropoiesis
- (2014) Min Xu et al. NATURE MEDICINE
- Caloric restriction mimetics: towards a molecular definition
- (2014) Frank Madeo et al. NATURE REVIEWS DRUG DISCOVERY
- How do glycolytic enzymes favour cancer cell proliferation by nonmetabolic functions?
- (2014) H Lincet et al. ONCOGENE
- 6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27
- (2014) A Yalcin et al. Cell Death & Disease
- PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells
- (2014) Yuhui Jiang et al. Nature Communications
- Nuclear localization of aldolase A correlates with cell proliferation
- (2013) Piotr Mamczur et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer
- (2013) Chenfang Dong et al. CANCER CELL
- Influence of Metabolism on Epigenetics and Disease
- (2013) William G. Kaelin et al. CELL
- PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells
- (2013) William J. Israelsen et al. CELL
- microRNA-7 Suppresses the Invasive Potential of Breast Cancer Cells and Sensitizes Cells to DNA Damages by Targeting Histone Methyltransferase SET8
- (2013) Na Yu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Akt inhibition promotes hexokinase 2 redistribution and glucose uptake in cancer cells
- (2013) Catherine L. Neary et al. JOURNAL OF CELLULAR PHYSIOLOGY
- PKM2 Regulates Chromosome Segregation and Mitosis Progression of Tumor Cells
- (2013) Yuhui Jiang et al. MOLECULAR CELL
- Mammalian DNA repair: HATs and HDACs make their mark through histone acetylation
- (2013) Fade Gong et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Double-strand break repair: 53BP1 comes into focus
- (2013) Stephanie Panier et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1 -mediated glucose metabolism
- (2013) H.-J. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Acetyl-CoA induces transcription of the key G1 cyclin CLN3 to promote entry into the cell division cycle in Saccharomyces cerevisiae
- (2013) L. Shi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Mitochondrial Nucleoid: Integrating Mitochondrial DNA into Cellular Homeostasis
- (2013) R. Gilkerson et al. Cold Spring Harbor Perspectives in Biology
- A BRISC-SHMT Complex Deubiquitinates IFNAR1 and Regulates Interferon Responses
- (2013) Hui Zheng et al. Cell Reports
- PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis
- (2012) Weiwei Yang et al. CELL
- Metabolic Regulation of Epigenetics
- (2012) Chao Lu et al. Cell Metabolism
- The Acetylase/Deacetylase Couple CREB-binding Protein/Sirtuin 1 Controls Hypoxia-inducible Factor 2 Signaling
- (2012) Rui Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting of Several Glycolytic Enzymes Using RNA Interference Reveals Aldolase Affects Cancer Cell Proliferation through a Non-glycolytic Mechanism
- (2012) Carolyn Ritterson Lew et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis
- (2012) Weiwei Yang et al. MOLECULAR CELL
- Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase
- (2012) Xueliang Gao et al. MOLECULAR CELL
- Serine is a natural ligand and allosteric activator of pyruvate kinase M2
- (2012) Barbara Chaneton et al. NATURE
- ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
- (2012) Weiwei Yang et al. NATURE CELL BIOLOGY
- Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
- (2012) Dimitrios Anastasiou et al. Nature Chemical Biology
- M2 isoform of pyruvate kinase is dispensable for tumor maintenance and growth
- (2012) M. Cortes-Cros et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death
- (2012) E. C. Cheung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcriptional integration of mitochondrial biogenesis
- (2012) Richard C. Scarpulla et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- An Antioxidant Response Phenotype Shared between Hereditary and Sporadic Type 2 Papillary Renal Cell Carcinoma
- (2011) Aikseng Ooi et al. CANCER CELL
- Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling
- (2011) Julie Adam et al. CANCER CELL
- Phosphoglucose Isomerase/Autocrine Motility Factor Mediates Epithelial-Mesenchymal Transition Regulated by miR-200 in Breast Cancer Cells
- (2011) A. Ahmad et al. CANCER RESEARCH
- Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
- (2011) Weibo Luo et al. CELL
- Autocrine motility factor/phosphoglucose isomerase regulates ER stress and cell death through control of ER calcium release
- (2011) M Fu et al. CELL DEATH AND DIFFERENTIATION
- Methionine Adenosyltransferase II Serves as a Transcriptional Corepressor of Maf Oncoprotein
- (2011) Yasutake Katoh et al. MOLECULAR CELL
- Acetyl-CoA Induces Cell Growth and Proliferation by Promoting the Acetylation of Histones at Growth Genes
- (2011) Ling Cai et al. MOLECULAR CELL
- Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation
- (2011) Weiwei Yang et al. NATURE
- The Polycomb complex PRC2 and its mark in life
- (2011) Raphaël Margueron et al. NATURE
- Promoter Hypermethylation Mediated Downregulation of FBP1 in Human Hepatocellular Carcinoma and Colon Cancer
- (2011) Mingquan Chen et al. PLoS One
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining
- (2010) S. Fnu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fumarase: A Mitochondrial Metabolic Enzyme and a Cytosolic/Nuclear Component of the DNA Damage Response
- (2010) Ohad Yogev et al. PLOS BIOLOGY
- Succinyl-CoA Synthetase Is a Phosphate Target for the Activation of Mitochondrial Metabolism
- (2009) Darci Phillips et al. BIOCHEMISTRY
- Phosphoglucose Isomerase/Autocrine Motility Factor Mediates Epithelial and Mesenchymal Phenotype Conversions in Breast Cancer
- (2009) Tatsuyoshi Funasaka et al. CANCER RESEARCH
- LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast Cancer
- (2009) Yan Wang et al. CELL
- A nucleocytoplasmic malate dehydrogenase regulates p53 transcriptional activity in response to metabolic stress
- (2009) S M Lee et al. CELL DEATH AND DIFFERENTIATION
- Nuclear Targeting of 6-Phosphofructo-2-kinase (PFKFB3) Increases Proliferation via Cyclin-dependent Kinases
- (2009) Abdullah Yalcin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- GOSPEL: A Neuroprotective Protein that Binds to GAPDH upon S-Nitrosylation
- (2009) Nilkantha Sen et al. NEURON
- ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
- (2009) K. E. Wellen et al. SCIENCE
- Improved Identification of von Hippel-Lindau Gene Alterations in Clear Cell Renal Tumors
- (2008) M. L. Nickerson et al. CLINICAL CANCER RESEARCH
- The Activated Notch1 Receptor Cooperates with -Enolase and MBP-1 in Modulating c-myc Activity
- (2008) K.-W. Hsu et al. MOLECULAR AND CELLULAR BIOLOGY
- The Multifunctional Protein Glyceraldehyde-3-Phosphate Dehydrogenase Is Both Regulated and Controls Colony-Stimulating Factor-1 Messenger RNA Stability in Ovarian Cancer
- (2008) Y. Zhou et al. MOLECULAR CANCER RESEARCH
- Pyruvate kinase M2 is a phosphotyrosine-binding protein
- (2008) Heather R. Christofk et al. NATURE
- The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
- (2008) Heather R. Christofk et al. NATURE
- Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis
- (2008) Nilkantha Sen et al. NATURE CELL BIOLOGY
- Hexokinase II Detachment from Mitochondria Triggers Apoptosis through the Permeability Transition Pore Independent of Voltage-Dependent Anion Channels
- (2008) Federica Chiara et al. PLoS One
- Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription
- (2007) Jungwoon Lee et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now