Searching for the gut microbial contributing factors to social behavior in rodent models of autism spectrum disorder

Infant Gut Microbiome Associated With Cognitive Development

(2018) Alexander L. Carlson et al.   BIOLOGICAL PSYCHIATRY

The microbiome regulates amygdala-dependent fear recall

(2017) A E Hoban et al.   MOLECULAR PSYCHIATRY

Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring

(2017) Sangdoo Kim et al.   NATURE

An intra-amygdala circuit specifically regulates social fear learning

(2017) Robert C Twining et al.   NATURE NEUROSCIENCE

Transmission of the gut microbiota: spreading of health

(2017) Hilary P. Browne et al.   NATURE REVIEWS MICROBIOLOGY

Input-Timing-Dependent Plasticity in the Hippocampal CA2 Region and Its Potential Role in Social Memory

(2017) Felix Leroy et al.   NEURON

Maternal Immune Activation Causes Behavioral Impairments and Altered Cerebellar Cytokine and Synaptic Protein Expression

(2017) Gurudutt Pendyala et al.   NEUROPSYCHOPHARMACOLOGY

Effects of ω-3 fatty acids on stereotypical behavior and social interactions in Wistar rats prenatally exposed to lipopolysaccarides

(2017) Jucélia Jeremias Fortunato et al.   NUTRITION

Sex-specific gene–environment interactions underlying ASD-like behaviors

(2017) Sara M. Schaafsma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gating of social reward by oxytocin in the ventral tegmental area

(2017) Lin W. Hung et al.   SCIENCE

Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior

(2017) Sophie Leclercq et al.   Nature Communications

Sex-related alterations of gut microbiota composition in the BTBR mouse model of autism spectrum disorder

(2017) Lorena Coretti et al.   Scientific Reports

Microbiota regulates visceral pain in the mouse

(2017) Pauline Luczynski et al.   eLife

Vitamin D treatment during pregnancy prevents autism-related phenotypes in a mouse model of maternal immune activation

(2017) Stephanie Vuillermot et al.   Molecular Autism

Environmental risk factors for autism: an evidence-based review of systematic reviews and meta-analyses

(2017) Amirhossein Modabbernia et al.   Molecular Autism

Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment

(2017) D Mattei et al.   Translational Psychiatry

Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study

(2017) Dae-Wook Kang et al.   Microbiome

Serotonin rebalances cortical tuning and behavior linked to autism symptoms in 15q11-13 CNV mice

(2017) Nobuhiro Nakai et al.   Science Advances

Microbiota-related Changes in Bile Acid & Tryptophan Metabolism are Associated with Gastrointestinal Dysfunction in a Mouse Model of Autism

(2017) Anna V. Golubeva et al.   EBioMedicine

Effect of Lactobacillus rhamnosus HN001 in Pregnancy on Postpartum Symptoms of Depression and Anxiety: A Randomised Double-blind Placebo-controlled Trial

(2017) R.F. Slykerman et al.   EBioMedicine

Ketogenic diet improves behaviors in a maternal immune activation model of autism spectrum disorder

(2017) David N. Ruskin et al.   PLoS One

Bifidobacterium in the gut microbiota confer resilience to chronic social defeat stress in mice

(2017) Chun Yang et al.   Scientific Reports

Absence of gut microbiota influences lipopolysaccharide-induced behavioral changes in mice

(2016) Alline C. Campos et al.   BEHAVIOURAL BRAIN RESEARCH

Widespread alterations in the synaptic proteome of the adolescent cerebral cortex following prenatal immune activation in rats

(2016) Balázs A. Györffy et al.   BRAIN BEHAVIOR AND IMMUNITY

Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication

(2016) Esther E. Fröhlich et al.   BRAIN BEHAVIOR AND IMMUNITY

Dorsal Raphe Dopamine Neurons Represent the Experience of Social Isolation

(2016) Gillian A. Matthews et al.   CELL

Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring

(2016) Shelly A. Buffington et al.   CELL

Adult microbiota-deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus

(2016) Pauline Luczynski et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Long-term safety assessment in children who received hydrolyzed protein formulas with Lactobacillus rhamnosus GG: a 5-year follow-up

(2016) DMF Scalabrin et al.   EUROPEAN JOURNAL OF PEDIATRICS

Metabolomic Modeling To Monitor Host Responsiveness to Gut Microbiota Manipulation in the BTBRT+tf/j Mouse

(2016) Matthias S. Klein et al.   JOURNAL OF PROTEOME RESEARCH

Targeted activation of the hippocampal CA2 area strongly enhances social memory

(2016) A S Smith et al.   MOLECULAR PSYCHIATRY

The bacterial peptidoglycan-sensing molecule Pglyrp2 modulates brain development and behavior

(2016) T Arentsen et al.   MOLECULAR PSYCHIATRY

Oxytocin Enhances Social Recognition by Modulating Cortical Control of Early Olfactory Processing

(2016) Lars-Lennart Oettl et al.   NEURON

Chemogenetic and Optogenetic Activation of Gαs Signaling in the Basolateral Amygdala Induces Acute and Social Anxiety-Like States

(2016) Edward R Siuda et al.   NEUROPSYCHOPHARMACOLOGY

Maternal gut and fetal brain connection: Increased anxiety and reduced social interactions in Wistar rat offspring following peri-conceptional antibiotic exposure

(2016) Stéphanie Degroote et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Dietary docosahexaenoic acid alleviates autistic-like behaviors resulting from maternal immune activation in mice

(2016) Michael J. Weiser et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Maternal immune activation: Implications for neuropsychiatric disorders

(2016) M. L. Estes et al.   SCIENCE

The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring

(2016) G. B. Choi et al.   SCIENCE

Ventral CA1 neurons store social memory

(2016) T. Okuyama et al.   SCIENCE

Cospeciation of gut microbiota with hominids

(2016) A. H. Moeller et al.   SCIENCE

The transgenerational inheritance of autism-like phenotypes in mice exposed to valproic acid during pregnancy

(2016) Chang Soon Choi et al.   Scientific Reports

Microbiota Modulates Behavior and Protein Kinase C mediated cAMP response element-binding protein Signaling

(2016) Li Zeng et al.   Scientific Reports

The early infant gut microbiome varies in association with a maternal high-fat diet

(2016) Derrick M. Chu et al.   Genome Medicine

Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior

(2016) Mar Gacias et al.   eLife

Ketogenic diet modifies the gut microbiota in a murine model of autism spectrum disorder

(2016) Christopher Newell et al.   Molecular Autism

Maternal high-fat diet prevents developmental programming by early-life stress

(2016) M Rincel et al.   Translational Psychiatry

Regulation of prefrontal cortex myelination by the microbiota

(2016) A E Hoban et al.   Translational Psychiatry

Administration of Non-Absorbable Antibiotics to Pregnant Mice to Perturb the Maternal Gut Microbiota Is Associated with Alterations in Offspring Behavior

(2016) Shiro Tochitani et al.   PLoS One

Adult Hippocampal Neurogenesis Is Regulated by the Microbiome

(2015) Ebere S. Ogbonnaya et al.   BIOLOGICAL PSYCHIATRY

Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour

(2015) Lieve Desbonnet et al.   BRAIN BEHAVIOR AND IMMUNITY

Microbes & neurodevelopment – Absence of microbiota during early life increases activity-related transcriptional pathways in the amygdala

(2015) Roman M. Stilling et al.   BRAIN BEHAVIOR AND IMMUNITY

The interaction between maternal immune activation and alpha 7 nicotinic acetylcholine receptor in regulating behaviors in the offspring

(2015) Wei-Li Wu et al.   BRAIN BEHAVIOR AND IMMUNITY

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

The Vomeronasal System Mediates Sick Conspecific Avoidance

(2015) Madlaina Boillat et al.   CURRENT BIOLOGY

Maternal high-fat diet programming of the neuroendocrine system and behavior

(2015) Elinor L. Sullivan et al.   HORMONES AND BEHAVIOR

A catalog of the mouse gut metagenome

(2015) Liang Xiao et al.   NATURE BIOTECHNOLOGY

Stress and the social brain: behavioural effects and neurobiological mechanisms

(2015) Carmen Sandi et al.   NATURE REVIEWS NEUROSCIENCE

A possible link between early probiotic intervention and the risk of neuropsychiatric disorders later in childhood: a randomized trial

(2015) Anna Pärtty et al.   PEDIATRIC RESEARCH

Microbiota and host determinants of behavioural phenotype in maternally separated mice

(2015) G. De Palma et al.   Nature Communications

Social networks predict gut microbiome composition in wild baboons

(2015) Jenny Tung et al.   eLife

Dietary supplementation with n-3 fatty acids from weaning limits brain biochemistry and behavioural changes elicited by prenatal exposure to maternal inflammation in the mouse model

(2015) Q Li et al.   Translational Psychiatry

Natural Neural Projection Dynamics Underlying Social Behavior

(2014) Lisa A. Gunaydin et al.   CELL

Dietary intervention rescues maternal obesity induced behavior deficits and neuroinflammation in offspring

(2014) Silvia S Kang et al.   Journal of Neuroinflammation

Amygdala Inputs to the Ventral Hippocampus Bidirectionally Modulate Social Behavior

(2014) A. C. Felix-Ortiz et al.   JOURNAL OF NEUROSCIENCE

The hippocampal CA2 region is essential for social memory

(2014) Frederick L. Hitti et al.   NATURE

Maternal immune activation and abnormal brain development across CNS disorders

(2014) Irene Knuesel et al.   Nature Reviews Neurology

Subchronic Treatment of Donepezil Rescues Impaired Social, Hyperactive, and Stereotypic Behavior in Valproic Acid-Induced Animal Model of Autism

(2014) Ji-Woon Kim et al.   PLoS One

Maternal Obesity Is Associated with Alterations in the Gut Microbiome in Toddlers

(2014) Jeffrey D. Galley et al.   PLoS One

Absence of the gut microbiota enhances anxiety-like behavior and neuroendocrine response to acute stress in rats

(2014) Michèle Crumeyrolle-Arias et al.   PSYCHONEUROENDOCRINOLOGY

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

High-fat maternal diet during pregnancy persistently alters the offspring microbiome in a primate model

(2014) Jun Ma et al.   Nature Communications

Friends with social benefits: host-microbe interactions as a driver of brain evolution and development?

(2014) Roman M. Stilling et al.   Frontiers in Cellular and Infection Microbiology

Reversal of autism-like behaviors and metabolism in adult mice with single-dose antipurinergic therapy

(2014) J C Naviaux et al.   Translational Psychiatry

Maternal Dietary Fat Intake in Association With Autism Spectrum Disorders

(2013) Kristen Lyall et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Inhibition of histone deacetylase in utero causes sociability deficits in postnatal mice

(2013) Randal X. Moldrich et al.   BEHAVIOURAL BRAIN RESEARCH

Psychobiotics: A Novel Class of Psychotropic

(2013) Timothy G. Dinan et al.   BIOLOGICAL PSYCHIATRY

Intestinal inflammation in a murine model of autism spectrum disorders

(2013) Caroline G.M. de Theije et al.   BRAIN BEHAVIOR AND IMMUNITY

Altered gut microbiota and activity in a murine model of autism spectrum disorders

(2013) Caroline G.M. de Theije et al.   BRAIN BEHAVIOR AND IMMUNITY

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

Probiotic Lactobacillus reuteri Attenuates the Stressor-Enhanced Severity of Citrobacter rodentium Infection

(2013) Amy R. Mackos et al.   INFECTION AND IMMUNITY

Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism

(2013) Jakob Christensen et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs

(2013) R. L. Bromley et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Microbiota is essential for social development in the mouse

(2013) L Desbonnet et al.   MOLECULAR PSYCHIATRY

Reduced Incidence of Prevotella and Other Fermenters in Intestinal Microflora of Autistic Children

(2013) Dae-Wook Kang et al.   PLoS One

Fecal Microbiota and Metabolome of Children with Autism and Pervasive Developmental Disorder Not Otherwise Specified

(2013) Maria De Angelis et al.   PLoS One

Common polymorphism in the oxytocin receptor gene (OXTR) is associated with human social recognition skills

(2013) David H. Skuse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Symbiotic bacteria appear to mediate hyena social odors

(2013) K. R. Theis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Hologenomic Basis of Speciation: Gut Bacteria Cause Hybrid Lethality in the Genus Nasonia

(2013) R. M. Brucker et al.   SCIENCE

The Evolution of Social Monogamy in Mammals

(2013) D. Lukas et al.   SCIENCE

Maternal immune activation and strain specific interactions in the development of autism-like behaviors in mice

(2013) J J Schwartzer et al.   Translational Psychiatry

Psychoactive bacteria Lactobacillus rhamnosus (JB-1) elicits rapid frequency facilitation in vagal afferents

(2012) Azucena Perez-Burgos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Gastrointestinal Dysfunction in Autism: Parental Report, Clinical Evaluation, and Associated Factors

(2012) Phillip Gorrindo et al.   Autism Research

Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism

(2012) Natalia V. Malkova et al.   BRAIN BEHAVIOR AND IMMUNITY

Maternal immune activation causes age- and region-specific changes in brain cytokines in offspring throughout development

(2012) Paula A. Garay et al.   BRAIN BEHAVIOR AND IMMUNITY

Does the Human Gut Microbiota Contribute to the Etiology of Autism Spectrum Disorders?

(2012) Petra Louis   DIGESTIVE DISEASES AND SCIENCES

Hypoactivity of the central dopaminergic system and autistic-like behavior induced by a single early prenatal exposure to lipopolysaccharide

(2012) Thiago B. Kirsten et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

(2012) G Clarke et al.   MOLECULAR PSYCHIATRY

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Neural mechanisms of social risk for psychiatric disorders

(2012) Andreas Meyer-Lindenberg et al.   NATURE NEUROSCIENCE

Maternal Metabolic Conditions and Risk for Autism and Other Neurodevelopmental Disorders

(2012) P. Krakowiak et al.   PEDIATRICS

Gastrointestinal Conditions in Children With Autism Spectrum Disorder: Developing a Research Agenda

(2012) Daniel L. Coury et al.   PEDIATRICS

Modeling an autism risk factor in mice leads to permanent immune dysregulation

(2012) E. Y. Hsiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A bacterial sulfonolipid triggers multicellular development in the closest living relatives of animals

(2012) Rosanna A Alegado et al.   eLife

State of the art; microbiology in health and disease. Intestinal bacterial flora in autism

(2011) Sydney M. Finegold   ANAEROBE

Biology and evolution of sexual transmission

(2011) Janis Antonovics et al.   Annals of the New York Academy of Sciences

Gastrointestinal flora and gastrointestinal status in children with autism – comparisons to typical children and correlation with autism severity

(2011) James B Adams et al.   BMC GASTROENTEROLOGY

Remote Control of Neuronal Signaling

(2011) S. C. Rogan et al.   PHARMACOLOGICAL REVIEWS

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

(2011) J. A. Bravo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Socially transmitted gut microbiota protect bumble bees against an intestinal parasite

(2011) H. Koch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normal gut microbiota modulates brain development and behavior

(2011) R. D. Heijtz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal infection and immune involvement in autism

(2011) Paul H. Patterson   TRENDS IN MOLECULAR MEDICINE

Prenatal Interaction of Mutant DISC1 and Immune Activation Produces Adult Psychopathology

(2010) Bagrat Abazyan et al.   BIOLOGICAL PSYCHIATRY

Effects of prenatal infection on brain development and behavior: A review of findings from animal models

(2010) Patricia Boksa   BRAIN BEHAVIOR AND IMMUNITY

Exposure to a social stressor alters the structure of the intestinal microbiota: Implications for stressor-induced immunomodulation

(2010) Michael T. Bailey et al.   BRAIN BEHAVIOR AND IMMUNITY

Chronic Gastrointestinal Inflammation Induces Anxiety-Like Behavior and Alters Central Nervous System Biochemistry in Mice

(2010) Premysl Bercik et al.   GASTROENTEROLOGY

Reduced scent marking and ultrasonic vocalizations in the BTBR T+tf/J mouse model of autism

(2010) M. Wöhr et al.   GENES BRAIN AND BEHAVIOR

Bacterial infection causes stress-induced memory dysfunction in mice

(2010) M. G. Gareau et al.   GUT

The Australian Brain and Cognition and Antiepileptic Drugs Study: IQ in School-Aged Children Exposed to Sodium Valproate and Polytherapy

(2010) Caroline Nadebaum et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Reduced anxiety-like behavior and central neurochemical change in germ-free mice

(2010) K. M. Neufeld et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The Challenge of Translation in Social Neuroscience: A Review of Oxytocin, Vasopressin, and Affiliative Behavior

(2010) Thomas R. Insel   NEURON

Behavioral and molecular changes in the mouse in response to prenatal exposure to the anti-epileptic drug valproic acid

(2010) F.I. Roullet et al.   NEUROSCIENCE

Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report

(2010) Timothy Buie et al.   PEDIATRICS

Commensal bacteria play a role in mating preference of Drosophila melanogaster

(2010) G. Sharon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The critical period of valproate exposure to induce autistic symptoms in Sprague–Dawley rats

(2010) Ki Chan Kim et al.   TOXICOLOGY LETTERS

Autism: The Empathizing-Systemizing (E-S) Theory

(2009) Simon Baron-Cohen   Annals of the New York Academy of Sciences

Behavior and serotonergic disorders in rats exposed prenatally to valproate: A model for autism

(2009) Diane Dufour-Rainfray et al.   NEUROSCIENCE LETTERS

Epidemiology-driven neurodevelopmental animal models of schizophrenia

(2009) Urs Meyer et al.   PROGRESS IN NEUROBIOLOGY

Immune involvement in schizophrenia and autism: Etiology, pathology and animal models

(2008) Paul H. Patterson   BEHAVIOURAL BRAIN RESEARCH

Early Life Stress Alters Behavior, Immunity, and Microbiota in Rats: Implications for Irritable Bowel Syndrome and Psychiatric Illnesses

(2008) Siobhain M. O'Mahony et al.   BIOLOGICAL PSYCHIATRY

Unusual Repertoire of Vocalizations in the BTBR T+tf/J Mouse Model of Autism

(2008) Maria Luisa Scattoni et al.   PLoS One

Campylobacter jejuni infection increases anxiety-like behavior in the holeboard: Possible anatomical substrates for viscerosensory modulation of exploratory behavior

(2007) Lisa E. Goehler et al.   BRAIN BEHAVIOR AND IMMUNITY

Autism-like behavioral phenotypes in BTBR T+tf/J mice

(2007) H. G. McFarlane et al.   GENES BRAIN AND BEHAVIOR