期刊
DALTON TRANSACTIONS
卷 47, 期 12, 页码 4017-4026出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8dt00089a
关键词
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资金
- Science and Technology Foundation of Shenzhen [JCYJ20170302144346218]
- National Natural Science Foundation of China (NSFC) [21701113]
- NSFC [21671137]
Chiral natural biological molecules, such as nucleic acids and proteins, guide the research of chiral compounds. Chiral metal-based drugs are currently an interesting and rapidly growing field in anticancer research. This perspective focuses on chiral metal compounds with application in cancer chemotherapy. The different chiral metal-based anticancer agents and the extent to which the chiral resolution affects their biological properties are discussed. This perspective will aid the design of new potent and efficient chiral metal-based anticancer drugs that exploit their unique properties combined with their potential selectivity toward targeted chiral biomolecules.
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